Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 158422378

GI number: 158422378

Start: 848578

End: 849558

Strand: Direct

Name: qor [H]

Synonym: AZC_0754

Alternate gene names: 158422378

Gene position: 848578-849558 (Clockwise)

Preceding gene: 158422371

Following gene: 158422382

Centisome position: 15.8

GC content: 69.22

Gene sequence:

>981_bases
ATGAAGGCTGTCCTGTGCGTCCGCCACGCTCCGCCCGAGGCTCTTGAGATCGTGGACCTGCCCGATCCCGTGGCCGGTCC
CGGCGAGGTGGTGGTGGAAGTGGCCGCCGTCGGCCTCAATTTCTTCGACACCCTCATCATCCGCAACCTTTATCAGCAGA
AGCCCGATCTGCCCTTCTCGCCCGGTGGCGAGTTCGCCGGCCGTGTCCTGGCGCTGGGGCCGGGCGTGACCGGGCCGAAG
GTCGGCACCCGCGTCTGCGGCAACGTCGGTTATGGCGCGGCCCGCGAGCGCCTCGTGGTGCGCGCCGACCGGCTTGCGGT
CGTGCCGGACGATCTCGATCTCGTGCGCGCCGCCGGCCTCATCATCACCTATGGCACCAGCCTCTATGCCCTGCGCGACC
GCGGCGAGCTGAAGGCCGGCGAGACGCTGGTGGTCCTGGGAGCCGCTGGCGGCGTCGGTCTCGCGGCGGTGGAACTGGGC
AAGATCCTCGGCGCCCGCGTCATCGCCTGCGCCTCCTCTCCGGACAAGATCGCCTTCGCCCGCAGCCACGGTGCCGATAT
CGGCATCGATTACACCACGGAAAACCTGAAGCTGCGCCTCAAGGAACTCACCGGCGGTGAGGGTGCGGATGTGGTCTACG
ATCCGGTGGGCGGCGACCTCTCCGAACAGGCGCTGCGCTCGCTCGGCTGGTGCGGGCGGCTGCTGGTCATCGGTTTCGCG
GCGGGCGAAATTCCGAAGCTGCCGCTGAACCTGCTGCTGCTCAAGAATTGCGACGCGCGGGGCGTCGCCTTCGGCACGCA
GGCCATGCGCGATCCCGCCTGGCTGACGGCGACCATCACCGAACTCATGGGCTATGCCCGCTCGGGAGCCATCTCCGCCC
ATGTGGACGCGACCTTCCCGCTGGAGCGCTGCGCCGAGGCGCTGGGCGAGATCGCCGGCCGGAAGGTGAAGGGCAAGGTG
GTGCTCACCACCGGCCTGTGA

Upstream 100 bases:

>100_bases
TTTTGATGGGAGCCGGTTCCAGGGTGTGGCGTGCCTGCGGCAGCGCCCGCGTCTGATGGATCAGGGGCGCTCATCCACGG
AAGGGGAGACGAATCGTCCC

Downstream 100 bases:

>100_bases
CCGGCGTCAGCCCTCTCGGGCCCGCCGCAGGGCCTCATCGGCCGCTTCGCGATGGTGCGGCTTGATGTGGTTGGCGAGCA
GCTGGAGCGCGCCGAACAGC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKAVLCVRHAPPEALEIVDLPDPVAGPGEVVVEVAAVGLNFFDTLIIRNLYQQKPDLPFSPGGEFAGRVLALGPGVTGPK
VGTRVCGNVGYGAARERLVVRADRLAVVPDDLDLVRAAGLIITYGTSLYALRDRGELKAGETLVVLGAAGGVGLAAVELG
KILGARVIACASSPDKIAFARSHGADIGIDYTTENLKLRLKELTGGEGADVVYDPVGGDLSEQALRSLGWCGRLLVIGFA
AGEIPKLPLNLLLLKNCDARGVAFGTQAMRDPAWLTATITELMGYARSGAISAHVDATFPLERCAEALGEIAGRKVKGKV
VLTTGL

Sequences:

>Translated_326_residues
MKAVLCVRHAPPEALEIVDLPDPVAGPGEVVVEVAAVGLNFFDTLIIRNLYQQKPDLPFSPGGEFAGRVLALGPGVTGPK
VGTRVCGNVGYGAARERLVVRADRLAVVPDDLDLVRAAGLIITYGTSLYALRDRGELKAGETLVVLGAAGGVGLAAVELG
KILGARVIACASSPDKIAFARSHGADIGIDYTTENLKLRLKELTGGEGADVVYDPVGGDLSEQALRSLGWCGRLLVIGFA
AGEIPKLPLNLLLLKNCDARGVAFGTQAMRDPAWLTATITELMGYARSGAISAHVDATFPLERCAEALGEIAGRKVKGKV
VLTTGL
>Mature_326_residues
MKAVLCVRHAPPEALEIVDLPDPVAGPGEVVVEVAAVGLNFFDTLIIRNLYQQKPDLPFSPGGEFAGRVLALGPGVTGPK
VGTRVCGNVGYGAARERLVVRADRLAVVPDDLDLVRAAGLIITYGTSLYALRDRGELKAGETLVVLGAAGGVGLAAVELG
KILGARVIACASSPDKIAFARSHGADIGIDYTTENLKLRLKELTGGEGADVVYDPVGGDLSEQALRSLGWCGRLLVIGFA
AGEIPKLPLNLLLLKNCDARGVAFGTQAMRDPAWLTATITELMGYARSGAISAHVDATFPLERCAEALGEIAGRKVKGKV
VLTTGL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=29.2993630573248, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=27.7439024390244, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=27.7439024390244, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI28557745, Length=247, Percent_Identity=34.412955465587, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24308257, Length=324, Percent_Identity=26.8518518518519, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI194239676, Length=325, Percent_Identity=26.7692307692308, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI67078404, Length=320, Percent_Identity=26.5625, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67078406, Length=295, Percent_Identity=27.1186440677966, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41872631, Length=278, Percent_Identity=28.7769784172662, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI47519420, Length=334, Percent_Identity=26.6467065868263, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=320, Percent_Identity=33.75, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17507255, Length=325, Percent_Identity=27.3846153846154, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=305, Percent_Identity=27.5409836065574, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=303, Percent_Identity=27.0627062706271, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=316, Percent_Identity=29.1139240506329, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323729, Length=286, Percent_Identity=25.1748251748252, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920632, Length=267, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221330659, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33942; Mature: 33942

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLCVRHAPPEALEIVDLPDPVAGPGEVVVEVAAVGLNFFDTLIIRNLYQQKPDLPFS
CCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PGGEFAGRVLALGPGVTGPKVGTRVCGNVGYGAARERLVVRADRLAVVPDDLDLVRAAGL
CCCHHCCEEEEECCCCCCCCHHHHHHCCCCCCHHHHEEEEEECCEEECCCCHHHHHHCCE
IITYGTSLYALRDRGELKAGETLVVLGAAGGVGLAAVELGKILGARVIACASSPDKIAFA
EEEECCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCEEEE
RSHGADIGIDYTTENLKLRLKELTGGEGADVVYDPVGGDLSEQALRSLGWCGRLLVIGFA
ECCCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
AGEIPKLPLNLLLLKNCDARGVAFGTQAMRDPAWLTATITELMGYARSGAISAHVDATFP
CCCCCCCCEEEEEEECCCCCCEEECHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCC
LERCAEALGEIAGRKVKGKVVLTTGL
HHHHHHHHHHHHCCEECCEEEEEECC
>Mature Secondary Structure
MKAVLCVRHAPPEALEIVDLPDPVAGPGEVVVEVAAVGLNFFDTLIIRNLYQQKPDLPFS
CCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PGGEFAGRVLALGPGVTGPKVGTRVCGNVGYGAARERLVVRADRLAVVPDDLDLVRAAGL
CCCHHCCEEEEECCCCCCCCHHHHHHCCCCCCHHHHEEEEEECCEEECCCCHHHHHHCCE
IITYGTSLYALRDRGELKAGETLVVLGAAGGVGLAAVELGKILGARVIACASSPDKIAFA
EEEECCEEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCCCEEEE
RSHGADIGIDYTTENLKLRLKELTGGEGADVVYDPVGGDLSEQALRSLGWCGRLLVIGFA
ECCCCEEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHCCCCEEEEEEEC
AGEIPKLPLNLLLLKNCDARGVAFGTQAMRDPAWLTATITELMGYARSGAISAHVDATFP
CCCCCCCCEEEEEEECCCCCCEEECHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCCC
LERCAEALGEIAGRKVKGKVVLTTGL
HHHHHHHHHHHHCCEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]