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The map label for this gene is hupT [H]

Identifier: 158422218

GI number: 158422218

Start: 659137

End: 660507

Strand: Direct

Name: hupT [H]

Synonym: AZC_0594

Alternate gene names: 158422218

Gene position: 659137-660507 (Clockwise)

Preceding gene: 158422217

Following gene: 158422219

Centisome position: 12.27

GC content: 68.85

Gene sequence:

>1371_bases
ATGTCCCTTCCGCACGATGATGGCGCTCCGCCCGTGCTCCCGGCCTCTGGCCTCGGGGCGGATGGTGCCGTGCCGGGTGC
CGAAGCCGAGCAGGCGTGGATCTCCGTCATCCAGAAGATGGACGAGACCTATGCCGAATTGCTGGCCCAGCAGGTGGAAC
TGGAGGCCAAGAACGAGGCGCTGGAGGAAGCGCATGCCTTCATCGCCGGCGTGATGGCCTCCATGACCGACGTGCTCATC
GCCTGCGATCTCGCTGGGCGCATCGAGCAAGTGAATGTGGCCGCCGAGCGCCTGTTCGGTCGCCCGGCCAGTGTCCTTCA
GGTGCAGCGCCTCGCCGATCTCATCGCGCCGGAATCTCCGGCCTCCTTCTCCGATGTTCTGACGACCGTCGCGCGGCGCG
AGCGGATCGCGGACCGGGACTTCACCTTCCTCACGCCGGAGGGGCCGCTGCCGGTTTCGGTCAACGGCGCCATCCGCTTT
GATCCGCGCGGGCGGGCCGTGGGCATCACCCTCATGGGCCGGCCGGTGGGCGAGCTGCGCAAGGCCTATAGCGACCTTGC
CGCCGCCCATGAACGTCTGAAGGAAACCCAGCAGCAACTGGTGCAGGCGGAGAAGATGGCCTCTCTCGGCCGTCTGGTGG
CCGGCGTCGCGCACGAGCTGAACAATCCCATCTCGTTCGTCTATGGCAACGCCCACACCATGAAGCGCTATGCCGAGCGC
CTCGCCACCTATCTCGACGCGCTGCATGGCGCCCCGAGCCCGGCCGCCGTCTCGGGCCTGCGCGGTGAGCTGAAGATCGA
CCGCACATTGGCCGAGCTCGGTCCGACGCTCGCCGGCATGCTGGAAGGCGCCGAGCGGGTGCGCGACATCGTGGCGGACC
TGCGCCGCTTCTCGTCCGACCGGCGGCAGGGCGACGAGGCGGTGGACATGGCCGGCCTCGTGCGCTCGGCGCTCGATTGG
GTGGCCAAGGCCCAGCAGCCTGACGTGGCCATCTTCACCGATCTGCCGGACGGGCTGGACGTGACCGGGCATCCGGGGCA
ACTGCATCAGGTGATGATGAACCTCGTCCAGAACGCCCTTGATGCGCTGGAGGGCGCGCCCGTCCGCCGGCTCGAAATCA
CCGGCCGGCGCGAGGGCGAGCGCGTGGTCGTGCGGGTGCGTGACAGTGGCCCCGGCATCGCGCCGGATATTCTCTCGCGG
GTGTTCGATCCCTTCTTCACCACCAAGCCGGTTGGCAAGGGCACGGGCCTCGGCCTGTCCATCTGCTATCGGATCGTCCA
GGAGCACGAGGGCACGCTTGCCGCCGCCAATGCCCCCGAGGGCGGTGCGGTGATGACCCTGAGCCTGCCCGCCGCCGGGA
GCACGCCATGA

Upstream 100 bases:

>100_bases
GTGAGCCGCATCCGAGCGCGCCGCCCACCAACGCGCCGCCCTTGGCGTTCGCCCGCCGGCGGGCGTAGCATGCGGGCCGT
CGCTGCAACCGGTTCCGGTC

Downstream 100 bases:

>100_bases
CGGTCCAATCCCGCGCCCATGGCTTCAACGTGCTCTGGCTGCAATCGGGCGGCTGCGGCGGCTGCACCATGTCGCTGCTC
TGCGCCGAGGCGCCGGACCT

Product: HupT protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSLPHDDGAPPVLPASGLGADGAVPGAEAEQAWISVIQKMDETYAELLAQQVELEAKNEALEEAHAFIAGVMASMTDVLI
ACDLAGRIEQVNVAAERLFGRPASVLQVQRLADLIAPESPASFSDVLTTVARRERIADRDFTFLTPEGPLPVSVNGAIRF
DPRGRAVGITLMGRPVGELRKAYSDLAAAHERLKETQQQLVQAEKMASLGRLVAGVAHELNNPISFVYGNAHTMKRYAER
LATYLDALHGAPSPAAVSGLRGELKIDRTLAELGPTLAGMLEGAERVRDIVADLRRFSSDRRQGDEAVDMAGLVRSALDW
VAKAQQPDVAIFTDLPDGLDVTGHPGQLHQVMMNLVQNALDALEGAPVRRLEITGRREGERVVVRVRDSGPGIAPDILSR
VFDPFFTTKPVGKGTGLGLSICYRIVQEHEGTLAAANAPEGGAVMTLSLPAAGSTP

Sequences:

>Translated_456_residues
MSLPHDDGAPPVLPASGLGADGAVPGAEAEQAWISVIQKMDETYAELLAQQVELEAKNEALEEAHAFIAGVMASMTDVLI
ACDLAGRIEQVNVAAERLFGRPASVLQVQRLADLIAPESPASFSDVLTTVARRERIADRDFTFLTPEGPLPVSVNGAIRF
DPRGRAVGITLMGRPVGELRKAYSDLAAAHERLKETQQQLVQAEKMASLGRLVAGVAHELNNPISFVYGNAHTMKRYAER
LATYLDALHGAPSPAAVSGLRGELKIDRTLAELGPTLAGMLEGAERVRDIVADLRRFSSDRRQGDEAVDMAGLVRSALDW
VAKAQQPDVAIFTDLPDGLDVTGHPGQLHQVMMNLVQNALDALEGAPVRRLEITGRREGERVVVRVRDSGPGIAPDILSR
VFDPFFTTKPVGKGTGLGLSICYRIVQEHEGTLAAANAPEGGAVMTLSLPAAGSTP
>Mature_455_residues
SLPHDDGAPPVLPASGLGADGAVPGAEAEQAWISVIQKMDETYAELLAQQVELEAKNEALEEAHAFIAGVMASMTDVLIA
CDLAGRIEQVNVAAERLFGRPASVLQVQRLADLIAPESPASFSDVLTTVARRERIADRDFTFLTPEGPLPVSVNGAIRFD
PRGRAVGITLMGRPVGELRKAYSDLAAAHERLKETQQQLVQAEKMASLGRLVAGVAHELNNPISFVYGNAHTMKRYAERL
ATYLDALHGAPSPAAVSGLRGELKIDRTLAELGPTLAGMLEGAERVRDIVADLRRFSSDRRQGDEAVDMAGLVRSALDWV
AKAQQPDVAIFTDLPDGLDVTGHPGQLHQVMMNLVQNALDALEGAPVRRLEITGRREGERVVVRVRDSGPGIAPDILSRV
FDPFFTTKPVGKGTGLGLSICYRIVQEHEGTLAAANAPEGGAVMTLSLPAAGSTP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=394, Percent_Identity=26.9035532994924, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790436, Length=256, Percent_Identity=33.59375, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693157, Length=278, Percent_Identity=25.8992805755396, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081816, Length=123, Percent_Identity=40.650406504065, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788393, Length=120, Percent_Identity=35, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=28.8321167883212, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=23.6559139784946, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790300, Length=302, Percent_Identity=25.1655629139073, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=117, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48610; Mature: 48479

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPHDDGAPPVLPASGLGADGAVPGAEAEQAWISVIQKMDETYAELLAQQVELEAKNEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEAHAFIAGVMASMTDVLIACDLAGRIEQVNVAAERLFGRPASVLQVQRLADLIAPESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ASFSDVLTTVARRERIADRDFTFLTPEGPLPVSVNGAIRFDPRGRAVGITLMGRPVGELR
CCHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCEEEECCCCCEEEEEEECCCHHHHH
KAYSDLAAAHERLKETQQQLVQAEKMASLGRLVAGVAHELNNPISFVYGNAHTMKRYAER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LATYLDALHGAPSPAAVSGLRGELKIDRTLAELGPTLAGMLEGAERVRDIVADLRRFSSD
HHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQGDEAVDMAGLVRSALDWVAKAQQPDVAIFTDLPDGLDVTGHPGQLHQVMMNLVQNAL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
DALEGAPVRRLEITGRREGERVVVRVRDSGPGIAPDILSRVFDPFFTTKPVGKGTGLGLS
HHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHH
ICYRIVQEHEGTLAAANAPEGGAVMTLSLPAAGSTP
HHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
SLPHDDGAPPVLPASGLGADGAVPGAEAEQAWISVIQKMDETYAELLAQQVELEAKNEA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEAHAFIAGVMASMTDVLIACDLAGRIEQVNVAAERLFGRPASVLQVQRLADLIAPESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
ASFSDVLTTVARRERIADRDFTFLTPEGPLPVSVNGAIRFDPRGRAVGITLMGRPVGELR
CCHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEECCEEEECCCCCEEEEEEECCCHHHHH
KAYSDLAAAHERLKETQQQLVQAEKMASLGRLVAGVAHELNNPISFVYGNAHTMKRYAER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHH
LATYLDALHGAPSPAAVSGLRGELKIDRTLAELGPTLAGMLEGAERVRDIVADLRRFSSD
HHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQGDEAVDMAGLVRSALDWVAKAQQPDVAIFTDLPDGLDVTGHPGQLHQVMMNLVQNAL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
DALEGAPVRRLEITGRREGERVVVRVRDSGPGIAPDILSRVFDPFFTTKPVGKGTGLGLS
HHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCCCHHH
ICYRIVQEHEGTLAAANAPEGGAVMTLSLPAAGSTP
HHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]