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The map label for this gene is ampG [H]

Identifier: 158422195

GI number: 158422195

Start: 632348

End: 633760

Strand: Reverse

Name: ampG [H]

Synonym: AZC_0571

Alternate gene names: 158422195

Gene position: 633760-632348 (Counterclockwise)

Preceding gene: 158422196

Following gene: 158422190

Centisome position: 11.8

GC content: 69.43

Gene sequence:

>1413_bases
GTGTCGAGCCGCCCGCCGCCCACGGAACAGGACATGAGCGAGAACACCCTCGAAGCCCCGGGCGCCCCCGCGTCGATGCT
CGATGCCGTGAAGGTCTATCTGCGCCCGAGCGTGCTGGTGGTGATCCTGCTCGGCTTCTCCTCGGGCCTGCCGCTGGCGC
TCACCGGCACCACGCTCGCGGTCTGGATGACCGAGCGCAAGGTGGACATCGCCACCATCGGCCTCTTCCATCTGGTCGGC
CTGCCCTACACGCTGAAGTTCCTCTGGGCGCCACTGGTGGATGCCCTCGACGTGCCGCTGCTCTCCCGCTGGCTCGGCCG
GCGGCGCGGCTGGCTGCTGGCCACGCAGCTGCTGCTCGCCGCCGCCATTCTCTATCTGGGCTTTCAGGATCTCGGCTTTG
CCCCTTCCGCCGACGGCACCCGCATGGCGGCGCCCTTCGGGCTCATCGTCGGAGCGGTGCTGGTGGCCTTCCTCTCCGCC
ACACAGGACATCGTGGTGGATGCCTATCGCGTGGAGAAGCTCGACACCTCCGAGCAGGCGGCCGGCATGGCCGGCTATGT
GGCAGCCTATCGCATCGGCATGCTGGTGTCCGGCGCCGGCATCATTGCCCTCGTGGCGTGGTTCGAGTTCAAGGGCCTGC
CGCACGCGCAGGTGTGGGCCTGGGGCTATGGCGTCGCTGCCGCCTGCATGGCGCTCGGCATCTTCGCGACCCTCATCGCC
CGCGAGCCGGACGGCGCACCGCGGGTCGCCCATGAGGGCGGGGCGCTCGGCGCCCTGAAGCGGGTCTTCACCACCGCCTT
CGGCGCCTTCTCCGAGTTCCTGACCCGGAGCCACGCCTTCGCCATCCTCGCCTTCGTCACCCTCTACAAATTCTCCGATG
CGCTGGCGGGCGGGCTCACCGCGTCCTTCGTCATCTCCATCGGCTTCGACAAGGCGACCTACGCCGCCATCGTGAAGGGC
GTCGGCCTCCTCGCGGCCCTGGCGGGCGGCTTTGCCGGCGGCATGCTGGCGCGGGGGCGCTCGCTGGTCACGTGCCTCTG
GATCGGCGGCGTGCTCCAGATGGCCTCCAACCTCGCCTTCTCCGTTCAGGCGATGATCGGGCCCGACGTGGGCTTCCTCA
CCTTCGCGATGATCGTCGAGAACTTCACCGGCGCCATCGGCACGGTGATCTTCGTCGCCTATCTCTCGTCCCTGTGCGGC
GCTCGCGCACACACGGCCACCCAATATGCCCTGCTGACCGCGCTCACCGCCGTCGGCCGCACCGTCCTCGCCTCGGGCGG
CGGCTATATCTATGACGTGACCGGCTGGGCGTGGTTCTTCGTCGTCACGGTCATCGCCGGCCTGCCGGGTCTCGCCCTGC
TCGGCTGGCTTCAGGCGCGCGGCCACTTCCGGGAGCTTGGGGCAAAGGGGTGA

Upstream 100 bases:

>100_bases
CAGCACGGCGGCCGGCTCAACCTCTAAATTAACATGCGCGCGGGCATGATGCCGCCGGCTTTCCCGCGCGGGCCGGCCCG
GCGCAGCCTCCCCGGCGCCA

Downstream 100 bases:

>100_bases
GCCTTACCCCTTGCGAAAGCGCGGGTGGCAGAAGGCCAGAAGGATGAGGGCGAGCGGCAGCGTCAGGTGGTCGGCGACGG
CGCCCGGTGGGGTCGCGGTC

Product: major facilitator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSSRPPPTEQDMSENTLEAPGAPASMLDAVKVYLRPSVLVVILLGFSSGLPLALTGTTLAVWMTERKVDIATIGLFHLVG
LPYTLKFLWAPLVDALDVPLLSRWLGRRRGWLLATQLLLAAAILYLGFQDLGFAPSADGTRMAAPFGLIVGAVLVAFLSA
TQDIVVDAYRVEKLDTSEQAAGMAGYVAAYRIGMLVSGAGIIALVAWFEFKGLPHAQVWAWGYGVAAACMALGIFATLIA
REPDGAPRVAHEGGALGALKRVFTTAFGAFSEFLTRSHAFAILAFVTLYKFSDALAGGLTASFVISIGFDKATYAAIVKG
VGLLAALAGGFAGGMLARGRSLVTCLWIGGVLQMASNLAFSVQAMIGPDVGFLTFAMIVENFTGAIGTVIFVAYLSSLCG
ARAHTATQYALLTALTAVGRTVLASGGGYIYDVTGWAWFFVVTVIAGLPGLALLGWLQARGHFRELGAKG

Sequences:

>Translated_470_residues
MSSRPPPTEQDMSENTLEAPGAPASMLDAVKVYLRPSVLVVILLGFSSGLPLALTGTTLAVWMTERKVDIATIGLFHLVG
LPYTLKFLWAPLVDALDVPLLSRWLGRRRGWLLATQLLLAAAILYLGFQDLGFAPSADGTRMAAPFGLIVGAVLVAFLSA
TQDIVVDAYRVEKLDTSEQAAGMAGYVAAYRIGMLVSGAGIIALVAWFEFKGLPHAQVWAWGYGVAAACMALGIFATLIA
REPDGAPRVAHEGGALGALKRVFTTAFGAFSEFLTRSHAFAILAFVTLYKFSDALAGGLTASFVISIGFDKATYAAIVKG
VGLLAALAGGFAGGMLARGRSLVTCLWIGGVLQMASNLAFSVQAMIGPDVGFLTFAMIVENFTGAIGTVIFVAYLSSLCG
ARAHTATQYALLTALTAVGRTVLASGGGYIYDVTGWAWFFVVTVIAGLPGLALLGWLQARGHFRELGAKG
>Mature_469_residues
SSRPPPTEQDMSENTLEAPGAPASMLDAVKVYLRPSVLVVILLGFSSGLPLALTGTTLAVWMTERKVDIATIGLFHLVGL
PYTLKFLWAPLVDALDVPLLSRWLGRRRGWLLATQLLLAAAILYLGFQDLGFAPSADGTRMAAPFGLIVGAVLVAFLSAT
QDIVVDAYRVEKLDTSEQAAGMAGYVAAYRIGMLVSGAGIIALVAWFEFKGLPHAQVWAWGYGVAAACMALGIFATLIAR
EPDGAPRVAHEGGALGALKRVFTTAFGAFSEFLTRSHAFAILAFVTLYKFSDALAGGLTASFVISIGFDKATYAAIVKGV
GLLAALAGGFAGGMLARGRSLVTCLWIGGVLQMASNLAFSVQAMIGPDVGFLTFAMIVENFTGAIGTVIFVAYLSSLCGA
RAHTATQYALLTALTAVGRTVLASGGGYIYDVTGWAWFFVVTVIAGLPGLALLGWLQARGHFRELGAKG

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI300360496, Length=150, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4757708, Length=150, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786636, Length=426, Percent_Identity=39.906103286385, Blast_Score=252, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI71996375, Length=153, Percent_Identity=30.0653594771242, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536531, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193205020, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536529, Length=153, Percent_Identity=30.0653594771242, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319697, Length=182, Percent_Identity=25.8241758241758, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49286; Mature: 49155

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRPPPTEQDMSENTLEAPGAPASMLDAVKVYLRPSVLVVILLGFSSGLPLALTGTTLA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEECCEEE
VWMTERKVDIATIGLFHLVGLPYTLKFLWAPLVDALDVPLLSRWLGRRRGWLLATQLLLA
EEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHH
AAILYLGFQDLGFAPSADGTRMAAPFGLIVGAVLVAFLSATQDIVVDAYRVEKLDTSEQA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGMAGYVAAYRIGMLVSGAGIIALVAWFEFKGLPHAQVWAWGYGVAAACMALGIFATLIA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REPDGAPRVAHEGGALGALKRVFTTAFGAFSEFLTRSHAFAILAFVTLYKFSDALAGGLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ASFVISIGFDKATYAAIVKGVGLLAALAGGFAGGMLARGRSLVTCLWIGGVLQMASNLAF
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SVQAMIGPDVGFLTFAMIVENFTGAIGTVIFVAYLSSLCGARAHTATQYALLTALTAVGR
EEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TVLASGGGYIYDVTGWAWFFVVTVIAGLPGLALLGWLQARGHFRELGAKG
HHHCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCC
>Mature Secondary Structure 
SSRPPPTEQDMSENTLEAPGAPASMLDAVKVYLRPSVLVVILLGFSSGLPLALTGTTLA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEECCEEE
VWMTERKVDIATIGLFHLVGLPYTLKFLWAPLVDALDVPLLSRWLGRRRGWLLATQLLLA
EEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHH
AAILYLGFQDLGFAPSADGTRMAAPFGLIVGAVLVAFLSATQDIVVDAYRVEKLDTSEQA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AGMAGYVAAYRIGMLVSGAGIIALVAWFEFKGLPHAQVWAWGYGVAAACMALGIFATLIA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
REPDGAPRVAHEGGALGALKRVFTTAFGAFSEFLTRSHAFAILAFVTLYKFSDALAGGLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ASFVISIGFDKATYAAIVKGVGLLAALAGGFAGGMLARGRSLVTCLWIGGVLQMASNLAF
HHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SVQAMIGPDVGFLTFAMIVENFTGAIGTVIFVAYLSSLCGARAHTATQYALLTALTAVGR
EEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TVLASGGGYIYDVTGWAWFFVVTVIAGLPGLALLGWLQARGHFRELGAKG
HHHCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]