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The map label for this gene is tolQ [H]

Identifier: 158422145

GI number: 158422145

Start: 576408

End: 577253

Strand: Direct

Name: tolQ [H]

Synonym: AZC_0521

Alternate gene names: 158422145

Gene position: 576408-577253 (Clockwise)

Preceding gene: 158422144

Following gene: 158422146

Centisome position: 10.73

GC content: 66.19

Gene sequence:

>846_bases
ATGCCTGCCGCTTTGCGCGGGCCGGGCCAGCCGAGGATTGAAGATGAGACCTGCCATCCGGGCGTGGGGGCGTCGATGAA
GAAGTGGACACCGGCGCTGGCGACGGCGCTCGTGCTTGCGGCCTCCGCGGCCTGGGCACAGGCGGACGTCGGATCGGCCG
CGCTTGCGGCGCCGACCGCCAACATCTCGCTCATCGGGCTGTTTCTCCAGGCGCATTTCGTCGTCAAGCTGGTGATGCTG
GGCCTTGTGGCCGCGTCCATCTGGGTCTGGGCGATCATCATCGACAAGACCCTGCTGTTCACCCGCACCCGCAAGGAAAT
GGACCGCTTCGAGCAGGTCTTCTGGTCGGGCCAGAGCCTTGAGGAACTGTATCGCTCCCTCGCCGGCCGGCCGAACCAGG
CCATGGCCGCGATCTTCGTCGCCGCCATGCGCGAGTGGAAGCGGACCTATGAGGGCGGGGCGAAGTCCCTCACCGGCCTC
AACCAGCGCATCGAGAAGGTAATGGACGTCACCATCTCCCGCGAGGTGGAGGCGCTGGAAAGCAAGCTTCTGGTGCTGGC
CACCGTCGGCTCGGCCGGCCCCTTCATCGGCCTGTTCGGCACGGTGTGGGGCATCATGACCTCGTTCCAGGCCATCGCGG
CGTCCAAGAACACCAATCTGGCGGTTGTGGCACCGGGCATCGCGGAAGCCCTTTTCGCGACCGCCATGGGCCTCATTGCG
GCCATTCCCGCGACCATCTTCTACAACAAGTTCGTCCATCAGGCGTCGCGGCAGGCACAGCGGCTCGAAGGCTTCGCCGA
CGAGTTCTCCGCCATCCTGTCGCGCCAGATCGACGAGCGGGGCTGA

Upstream 100 bases:

>100_bases
CGCCGCCGGCATGCTGCATCGCGGCCGATCGCCCAAGTTTGGACGCACTCCCCCTCGAAAGAGCGGGTGTGCTTCCTGAA
TTTGGAACGACGGACGGGCG

Downstream 100 bases:

>100_bases
ACCATGGGCATGGGCGGCGGCGCCGGAGGCGCATGGCAGAGCCGGCGGTCGCGCCGCCGGCGCAACGGCGGCATGATGGC
CGAGATCAACGTGACGCCCA

Product: TolQ protein precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPAALRGPGQPRIEDETCHPGVGASMKKWTPALATALVLAASAAWAQADVGSAALAAPTANISLIGLFLQAHFVVKLVML
GLVAASIWVWAIIIDKTLLFTRTRKEMDRFEQVFWSGQSLEELYRSLAGRPNQAMAAIFVAAMREWKRTYEGGAKSLTGL
NQRIEKVMDVTISREVEALESKLLVLATVGSAGPFIGLFGTVWGIMTSFQAIAASKNTNLAVVAPGIAEALFATAMGLIA
AIPATIFYNKFVHQASRQAQRLEGFADEFSAILSRQIDERG

Sequences:

>Translated_281_residues
MPAALRGPGQPRIEDETCHPGVGASMKKWTPALATALVLAASAAWAQADVGSAALAAPTANISLIGLFLQAHFVVKLVML
GLVAASIWVWAIIIDKTLLFTRTRKEMDRFEQVFWSGQSLEELYRSLAGRPNQAMAAIFVAAMREWKRTYEGGAKSLTGL
NQRIEKVMDVTISREVEALESKLLVLATVGSAGPFIGLFGTVWGIMTSFQAIAASKNTNLAVVAPGIAEALFATAMGLIA
AIPATIFYNKFVHQASRQAQRLEGFADEFSAILSRQIDERG
>Mature_280_residues
PAALRGPGQPRIEDETCHPGVGASMKKWTPALATALVLAASAAWAQADVGSAALAAPTANISLIGLFLQAHFVVKLVMLG
LVAASIWVWAIIIDKTLLFTRTRKEMDRFEQVFWSGQSLEELYRSLAGRPNQAMAAIFVAAMREWKRTYEGGAKSLTGLN
QRIEKVMDVTISREVEALESKLLVLATVGSAGPFIGLFGTVWGIMTSFQAIAASKNTNLAVVAPGIAEALFATAMGLIAA
IPATIFYNKFVHQASRQAQRLEGFADEFSAILSRQIDERG

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=41.2844036697248, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789381, Length=222, Percent_Identity=36.9369369369369, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30223; Mature: 30092

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAALRGPGQPRIEDETCHPGVGASMKKWTPALATALVLAASAAWAQADVGSAALAAPTA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
NISLIGLFLQAHFVVKLVMLGLVAASIWVWAIIIDKTLLFTRTRKEMDRFEQVFWSGQSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EELYRSLAGRPNQAMAAIFVAAMREWKRTYEGGAKSLTGLNQRIEKVMDVTISREVEALE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLLVLATVGSAGPFIGLFGTVWGIMTSFQAIAASKNTNLAVVAPGIAEALFATAMGLIA
HCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHH
AIPATIFYNKFVHQASRQAQRLEGFADEFSAILSRQIDERG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PAALRGPGQPRIEDETCHPGVGASMKKWTPALATALVLAASAAWAQADVGSAALAAPTA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
NISLIGLFLQAHFVVKLVMLGLVAASIWVWAIIIDKTLLFTRTRKEMDRFEQVFWSGQSL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EELYRSLAGRPNQAMAAIFVAAMREWKRTYEGGAKSLTGLNQRIEKVMDVTISREVEALE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKLLVLATVGSAGPFIGLFGTVWGIMTSFQAIAASKNTNLAVVAPGIAEALFATAMGLIA
HCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHH
AIPATIFYNKFVHQASRQAQRLEGFADEFSAILSRQIDERG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]