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The map label for this gene is ruvC

Identifier: 158422137

GI number: 158422137

Start: 571380

End: 571889

Strand: Direct

Name: ruvC

Synonym: AZC_0513

Alternate gene names: 158422137

Gene position: 571380-571889 (Clockwise)

Preceding gene: 158422136

Following gene: 158422138

Centisome position: 10.64

GC content: 70.78

Gene sequence:

>510_bases
ATGACCAACGGCATGATTCGCATCATCGGCCTCGATCCGGGCCTGCGCCGCACCGGCTGGGGCGTTATTGAGGCCCAGGG
CACGCGGCTCACCTATGTCGCCTGCGGCACCATCCTTCCGCCCGAGAACGCCCCCATGGCCGAGCGGCTCGCCGAGCTGC
ACCGGGGGCTTGCCGAGGTACTGGCCCGCCACGCGCCGGACGAGGCGGCGGTGGAAGAGACGTTCGTCAACATGAACCCG
TCCTCCACCCTCAAGCTCGGGCAGGCGCGCGGCGTCGTCATGCTGGCCCCGGCGCAGGCGGGGCTTTCGGTGGCGGAATA
CGCGCCGCTTCTGGTGAAGAAGACCGTGGTGGGCGCCGGCCGGGCGGAAAAGGCGCAGATCCGCATGATGATCGGCGTGC
TGCTGCCCAAGGCGACGCCGCAGACGGAGGATGCCGCCGACGCGCTGGCGGTGGCGGTGACTCATGCCCATCATCGCGGG
CCTGCTGCACTGCGGCGCGCGGCGCTGTAG

Upstream 100 bases:

>100_bases
AATGGGAAGTGGCCGGCCCGGCCGACGCCACGCCGCGCAAGTCCGCCTCCCGCTGAGGCATCGGGCTGGCGCCCCGGCGC
CGCCGGGGCCAGTTTGGCGC

Downstream 100 bases:

>100_bases
AATGGCGGAACGGGTTCGGCGGAGGGGACCGACATGCTGTGGGGCCAGCTTGCCCTGGTGACCGCGGCCCTGTTCACGGG
GGCCGCCTTCTATATCAATG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MTNGMIRIIGLDPGLRRTGWGVIEAQGTRLTYVACGTILPPENAPMAERLAELHRGLAEVLARHAPDEAAVEETFVNMNP
SSTLKLGQARGVVMLAPAQAGLSVAEYAPLLVKKTVVGAGRAEKAQIRMMIGVLLPKATPQTEDAADALAVAVTHAHHRG
PAALRRAAL

Sequences:

>Translated_169_residues
MTNGMIRIIGLDPGLRRTGWGVIEAQGTRLTYVACGTILPPENAPMAERLAELHRGLAEVLARHAPDEAAVEETFVNMNP
SSTLKLGQARGVVMLAPAQAGLSVAEYAPLLVKKTVVGAGRAEKAQIRMMIGVLLPKATPQTEDAADALAVAVTHAHHRG
PAALRRAAL
>Mature_168_residues
TNGMIRIIGLDPGLRRTGWGVIEAQGTRLTYVACGTILPPENAPMAERLAELHRGLAEVLARHAPDEAAVEETFVNMNPS
STLKLGQARGVVMLAPAQAGLSVAEYAPLLVKKTVVGAGRAEKAQIRMMIGVLLPKATPQTEDAADALAVAVTHAHHRGP
AALRRAAL

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=151, Percent_Identity=44.3708609271523, Blast_Score=107, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_AZOC5 (A8IM96)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523429.1
- ProteinModelPortal:   A8IM96
- SMR:   A8IM96
- GeneID:   5688025
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0513
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- BioCyc:   ACAU438753:AZC_0513-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 17794; Mature: 17663

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGMIRIIGLDPGLRRTGWGVIEAQGTRLTYVACGTILPPENAPMAERLAELHRGLAEV
CCCCEEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LARHAPDEAAVEETFVNMNPSSTLKLGQARGVVMLAPAQAGLSVAEYAPLLVKKTVVGAG
HHHCCCCHHHHHHHHCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC
RAEKAQIRMMIGVLLPKATPQTEDAADALAVAVTHAHHRGPAALRRAAL
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
TNGMIRIIGLDPGLRRTGWGVIEAQGTRLTYVACGTILPPENAPMAERLAELHRGLAEV
CCCEEEEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LARHAPDEAAVEETFVNMNPSSTLKLGQARGVVMLAPAQAGLSVAEYAPLLVKKTVVGAG
HHHCCCCHHHHHHHHCCCCCCCCEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCC
RAEKAQIRMMIGVLLPKATPQTEDAADALAVAVTHAHHRGPAALRRAAL
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA