Click here to switch to the map view.

The map label for this gene is tag [H]

Identifier: 158422026

GI number: 158422026

Start: 454555

End: 455142

Strand: Direct

Name: tag [H]

Synonym: AZC_0402

Alternate gene names: 158422026

Gene position: 454555-455142 (Clockwise)

Preceding gene: 158422025

Following gene: 158422029

Centisome position: 8.47

GC content: 66.67

Gene sequence:

>588_bases
GTGAGCGCTGATCGTATTCTGACGCCGCATAGCGACGGCAAGTGCCGCTGCCCCTGGTGCGGCACCGATCCGCTCTATGT
GGCCTATCACGACACCGAATGGGGCGTGCCCGAGCGCGACTCGCGCGCGCTGTTCGAGAAGCTGCTGCTGGACGGTTTCC
AGGCCGGGCTTGCCTGGATCACCATCCTGCGCAAGCGCGACAATTTCCGCCGCGCCTTCGACGGCTTTGAGCCGGAGGTG
ATCGCCGCCTATGGGCCGGAGAAGGTCGCGGCGCTGATGGCGGACGCCGGCATCGTGCGCAACCGGGCCAAGATCGAAGG
CGCGGTGCTCTCCGCCCGCGCCTATCTGGATCTTCGGGAGAAGGGCATCGCCTTCTCCGATTTCATGTGGGAGGCGGTGG
ACGGCACCGTGCAGGTGAACCGCCCCCGTACCCTCAAGGACATTCCCGCCGAGACGCCTGCCTCCCGCGCGCTCTCCAAG
AAATTGAAGGCGGCGGGCTTCAAATTCTGCGGCCCCACCATCGTCTACGCCGCCATGCAGGCCTGCGGCCTCGTGGACGA
CCATCTGGCGGAGTGCTGGCGGGCTTAG

Upstream 100 bases:

>100_bases
GCGCGGCGGAGGCGAAGGCCAGCGGCCTGCCGCTGTTGGCGGGCGATGTGGAAGTGACCCTGAAGGCGCCCGACTGGGCG
AGCTTCGACATGGAGGGCGT

Downstream 100 bases:

>100_bases
CCCGTTGGCGTGAGCTCGGGTATTGCCCGCTGCGGCCGGAACTGCCGCAAAGCCGCGAGGGCGGCGAGCGTCACCAGAGC
GCAGGCGGTGGCGAGAAGCA

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWITILRKRDNFRRAFDGFEPEV
IAAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLREKGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSK
KLKAAGFKFCGPTIVYAAMQACGLVDDHLAECWRA

Sequences:

>Translated_195_residues
MSADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWITILRKRDNFRRAFDGFEPEV
IAAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLREKGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSK
KLKAAGFKFCGPTIVYAAMQACGLVDDHLAECWRA
>Mature_194_residues
SADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWITILRKRDNFRRAFDGFEPEVI
AAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLREKGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSKK
LKAAGFKFCGPTIVYAAMQACGLVDDHLAECWRA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=177, Percent_Identity=54.2372881355932, Blast_Score=207, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21638; Mature: 21507

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWI
CCCCCCCCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TILRKRDNFRRAFDGFEPEVIAAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLRE
HHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSKKLKAAGFKFCGPTIVYAAMQ
CCCCHHHHHHHHCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ACGLVDDHLAECWRA
HHCCHHHHHHHHHCC
>Mature Secondary Structure 
SADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWI
CCCCCCCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
TILRKRDNFRRAFDGFEPEVIAAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLRE
HHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSKKLKAAGFKFCGPTIVYAAMQ
CCCCHHHHHHHHCCCEEEECCCCCHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ACGLVDDHLAECWRA
HHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]