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The map label for this gene is pbpG [H]

Identifier: 158421961

GI number: 158421961

Start: 389370

End: 391703

Strand: Reverse

Name: pbpG [H]

Synonym: AZC_0337

Alternate gene names: 158421961

Gene position: 391703-389370 (Counterclockwise)

Preceding gene: 158421963

Following gene: 158421957

Centisome position: 7.29

GC content: 69.11

Gene sequence:

>2334_bases
ATGACGGGACTCTTCATGGCTGGGCGCGGAACGGGCGGGCAGGAACGGCGCGAACCCTCGATGCGCGCAGCATCGGGATC
GCCCGAGCCGTCGTTCGACATCCGGCTCGATCCGGAAGACCGGCCGGGGGGCGGTCGCAAGCCTGCCCGCAAGGCGGACG
CCGCCGGCGGGGGCCGGCCGGCACGGGACCAGCGCGCGCGCGTCGAGCCGAGCCTCGATGGCGACGCCGCGGAAAGCGAG
GACATGGCCGCAGCCCCCCGCCGCAGCAAGACCGAGGGTTCGTCCCGAACCTCCAAGGGCTCCACCTCCTCGGGCGGCCG
CGGCAAGGCGAAATCCGAGCGGCGCCGCAAGCGCGGCTTCTTCTCCCTGTTCGGCCTCATCAAGTGGCTGTTCATCCTGG
GGCTGTGGGCGGCGGTTGGTGTGGGCGCGCTGGTGGCCTATGAGGCCTCCAAGCTGCCGCCCATGCAGACGCTGATGGTG
CCCAAGCGCCCGCCCACCGTCATGATCCAGTCCTTCGACGGCAAGCCTCTGGCCACGCGCGGCGACATGGGCGGGGCGGC
GGTGCCCATCAAGGAACTGCCCGCCTATCTGCCCAAGGCCTTCGTCGCCATCGAGGACCGGCGCTTCTACGACCATTTCG
GCCTCGACATCTGGGGTCTTGCCCGCGCCATGGCCGCCAATGCCGTCTCCCGCCGCGTGCGGCAGGGCGGCTCCACGCTC
ACCCAGCAGCTCGCCAAGAACCTCTTCCTCACGCAGGAGCGCACCTTCTCCCGCAAGATCCAGGAGCTGGTGCTGGCCCT
GTGGCTGGAGAAGAAGTTCACCAAGACCGAGATCCTCGATCTCTATCTGAACCGCGTCTATTTCGGGAACGGCGCCTATG
GCGTCGAGGCGGCGGCGCAGCGCTACTTCAACAAGTCGGCGCGCAACGTCACCCTGTCGGAGGCGGCCATGCTGGCGGGC
CTCGTCAATGCCCCCTCGCGCCTTGCGCCCACGCGCAACCTCAAGGCCGCGCAGGACCGCGCCAATCTCGTGCTCGCCGC
CATGCGCGAGCAGGGCTTCATCACCGAGGACATGGCGAAGGTGGCCCTCGCCCGCCCGGCGACGCTCGCCAAGCCCTCGA
CGCCCGATTCCATCGGCTATGTGGCCGACTGGGTGATGGACCAGCTCGATTCCTACGTGGGCACGCTGCCCGGCGACGTG
ATCGTGCGCACCACCATCGACCCCGTGCTCCAGCAGACGGCGCAGGCCTCGCTCACGGATGCGCTGAACAAGCAGGGCCA
GAAATACGGCGTCGGTCAGGGCGCCGTGGTCTCGCTCGACACGGACGGGGCCGTGAAGGCGCTGGTGGGCGGGCGCTCCT
ATGAGGACAGCCAGTACAACCGCGCCGTCACCGCGCGCCGTCAGCCGGGCTCCTCCTTCAAGCCCTTCATCTATCTCACC
GCGCTGGAAAAGGGCCTGACTCCCGAGACGGTGCGCGAGGACGGGCCGATCCAGCTCAAGGGCTGGAAGCCGGAGAATGC
CAGCCACCAGTATCTCGGCCCTGTTCAGCTCCAGCAGGCGCTCGCCATGTCGCTGAACACGGTCTCCGTGCGCCTCGCGC
TGGAAGTGGGGCCGAAAGCGGTGGTGGCGACCGCCCACCGGCTCGGCATCACCTCGACGCTCGATCCGAACCCGTCCATC
GCGCTCGGCACGTCGGAAGTCTCCGTGCTGGAGCTGGCCTCCGCTTACGTGCCCTTCGCCAATGGCGGCATCGGCGTCAT
CCCCTACGTGATCGAGAGCGTGAAGGGACCGGATGGCAAGATGCTCTATTCCCGCTCCACCTCGGGGCCGGGGCGGGTCA
TCGATCCGGCCTATGTGGGCATGATGAACCATATGCTGGAGCAGACCATCGCGGTGGGCACCGGCCGCCGCGCCGAGCTG
CCCGGCTGGGATGCCGCCGGCAAGACCGGCACCTCGCAGGATTATCGCGACGCCTGGTTCGTGGGCTACACGGCCCGCAT
CGTAACGGCGGTGTGGATCGGCAATGACGATTCCTCCCCCACCAAGAAGGCCTCAGGCGCCAATTTGCCGGCGGAGATCT
GGAGCCGCTACATGAAGGTGGCCCACAAGGACCTGCCGCCCACCGAACTGCCCGGTGCCGGCCGCAGCTATGTGGCCTCC
GGCACCTTCGGCTTCGGCCAGCAGGGCGGCATGCTGCCCCCCGGCCAGGTGCCGGACGAGGCGCCGCCGGCCATCGTCGG
CAACCTCCCGCCCCAGCAGCCGCGCCCGCAGCAGGATGAGCCCATGACGCTCGACCGCTGGTTCGTGGACACCTTCCTCG
GCGGCCGCAGGTGA

Upstream 100 bases:

>100_bases
ACGCCCGCGCGGGAATTGCACCGGCATCGGGGATGATCGGGTAACCGAACCTTAAATGGCCGCAATCGAAGGTCTTTGAG
GGTCTCCTCTCACGCAACGG

Downstream 100 bases:

>100_bases
CCCGGCCACCTCGCACCACCGACGCCTTGCGAGGCGTCGGCAGCGGGGACGTCACCGGCTGCCGACGGCGAGGACGAAGC
CCTTTTCCGTGAGCTGCATC

Product: penicillin-binding protein 1A

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MTGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRPARDQRARVEPSLDGDAAESE
DMAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGFFSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMV
PKRPPTVMIQSFDGKPLATRGDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTL
TQQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQRYFNKSARNVTLSEAAMLAG
LVNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAKVALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDV
IVRTTIDPVLQQTAQASLTDALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLT
ALEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKAVVATAHRLGITSTLDPNPSI
ALGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGKMLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAEL
PGWDAAGKTGTSQDYRDAWFVGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVAS
GTFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR

Sequences:

>Translated_777_residues
MTGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRPARDQRARVEPSLDGDAAESE
DMAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGFFSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMV
PKRPPTVMIQSFDGKPLATRGDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTL
TQQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQRYFNKSARNVTLSEAAMLAG
LVNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAKVALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDV
IVRTTIDPVLQQTAQASLTDALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLT
ALEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKAVVATAHRLGITSTLDPNPSI
ALGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGKMLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAEL
PGWDAAGKTGTSQDYRDAWFVGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVAS
GTFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR
>Mature_776_residues
TGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRPARDQRARVEPSLDGDAAESED
MAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGFFSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMVP
KRPPTVMIQSFDGKPLATRGDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTLT
QQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQRYFNKSARNVTLSEAAMLAGL
VNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAKVALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDVI
VRTTIDPVLQQTAQASLTDALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLTA
LEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKAVVATAHRLGITSTLDPNPSIA
LGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGKMLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAELP
GWDAAGKTGTSQDYRDAWFVGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVASG
TFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=575, Percent_Identity=34.2608695652174, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1788867, Length=580, Percent_Identity=32.5862068965517, Blast_Score=206, Evalue=6e-54,
Organism=Escherichia coli, GI87082258, Length=314, Percent_Identity=36.624203821656, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1789601, Length=165, Percent_Identity=38.7878787878788, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 83549; Mature: 83418

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRP
CCCEEEECCCCCCHHHCCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ARDQRARVEPSLDGDAAESEDMAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGF
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMVPKRPPTVMIQSFDGKPLATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCEEEEECCCCCCCCCC
GDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTL
CCCCCCCCCHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHH
TQQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
RYFNKSARNVTLSEAAMLAGLVNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAK
HHHHHHHCCEEHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
VALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDVIVRTTIDPVLQQTAQASLTD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHH
ALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLT
HHHHCCCEECCCCCCEEEECCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEE
ALEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKA
EHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEEECCCCH
VVATAHRLGITSTLDPNPSIALGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGK
HHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
MLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAELPGWDAAGKTGTSQDYRDAWF
EEEECCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVAS
HHHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
GTFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRP
CCEEEECCCCCCHHHCCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
ARDQRARVEPSLDGDAAESEDMAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGF
CCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMVPKRPPTVMIQSFDGKPLATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCEEEEECCCCCCCCCC
GDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTL
CCCCCCCCCHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHH
TQQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
RYFNKSARNVTLSEAAMLAGLVNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAK
HHHHHHHCCEEHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
VALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDVIVRTTIDPVLQQTAQASLTD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHH
ALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLT
HHHHCCCEECCCCCCEEEECCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEE
ALEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKA
EHHCCCCHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCEEEEEEEEECCCCH
VVATAHRLGITSTLDPNPSIALGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGK
HHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
MLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAELPGWDAAGKTGTSQDYRDAWF
EEEECCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVAS
HHHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEC
GTFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]