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The map label for this gene is 158421884

Identifier: 158421884

GI number: 158421884

Start: 305401

End: 306096

Strand: Reverse

Name: 158421884

Synonym: AZC_0260

Alternate gene names: NA

Gene position: 306096-305401 (Counterclockwise)

Preceding gene: 158421885

Following gene: 158421883

Centisome position: 5.7

GC content: 71.84

Gene sequence:

>696_bases
GTGCGCCTGCTCGTGACCCGCCCGCAACCGGGCGCCGGCGACACCGCCCGGCGTCTTGCGGCGCTGGGTCACGATGCGAT
CGTGGACCCCATGCTGCGGGTGGCGCAAACCCACGCGCCTTTACCCACCGGCGATTTCACTGCCATCGCCTTCACCAGCG
TGAATGGCGTGAAGGCGCTTGCCGCCCACGCGGAGAAGACCCGTGTACGGCATCTGCCCGCCTTCGCCGTGGGCAGCCGC
ACCGCCCAGGCCGCCCGCGCGGCCGGCTTCGCGGACGTGACCGACTGCGCCGGCGATGTGATCGCGCTCGGCACGGCACT
CAAGGCCCTGCCACCGGGCAGCCGCGTGCTCCATGCGGCAGGCGCGGAGCGGGCGGGCGATCTGGAAGGCGACCTCGCGC
CGGCCGGCATCAGCCTCGCCCTTGCGGTTCTCTACCGCACCCTCCCCGCCGATCAGCTCGCGCCGGAGACGCTCGCCGCC
CTCAAGAGCGGCGCGGTCGCGGCCGCGCTCCATTATTCCGCCCGCACGGTGGAGAGCCTGCTGGAGGCCACCGCACGCGG
GGACGTGACCGGACCCTTTCTTGCGCTGCGGCAGTTATGCCTGTCCCATGCGGTGGCGGCCCCGCTGCGGGCGCTGGGGG
CGACAACAGAGGTCTCACAAACTCCCGATGAGGACGCGCTGCTGACTTTGCTATAA

Upstream 100 bases:

>100_bases
GGACGAGACGGCCCCGGTCTCTGACGCCGCCCGGCTGGGCGCGGACATGGGCGCGCGGTTGCGCGCGACGGCTCCCGCCC
GCGCGCTGGGGCTCTAGGGC

Downstream 100 bases:

>100_bases
GGCTTCTAGGAAACGTGCCGTTCGCTCAGCGAAGGCGGATGAAACAAGGTGGTGAGCGGGCGCCGGCCGCCCCGAAGCCG
CCTGAATCAGAGCGACGGAT

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen III Synthase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRLLVTRPQPGAGDTARRLAALGHDAIVDPMLRVAQTHAPLPTGDFTAIAFTSVNGVKALAAHAEKTRVRHLPAFAVGSR
TAQAARAAGFADVTDCAGDVIALGTALKALPPGSRVLHAAGAERAGDLEGDLAPAGISLALAVLYRTLPADQLAPETLAA
LKSGAVAAALHYSARTVESLLEATARGDVTGPFLALRQLCLSHAVAAPLRALGATTEVSQTPDEDALLTLL

Sequences:

>Translated_231_residues
MRLLVTRPQPGAGDTARRLAALGHDAIVDPMLRVAQTHAPLPTGDFTAIAFTSVNGVKALAAHAEKTRVRHLPAFAVGSR
TAQAARAAGFADVTDCAGDVIALGTALKALPPGSRVLHAAGAERAGDLEGDLAPAGISLALAVLYRTLPADQLAPETLAA
LKSGAVAAALHYSARTVESLLEATARGDVTGPFLALRQLCLSHAVAAPLRALGATTEVSQTPDEDALLTLL
>Mature_231_residues
MRLLVTRPQPGAGDTARRLAALGHDAIVDPMLRVAQTHAPLPTGDFTAIAFTSVNGVKALAAHAEKTRVRHLPAFAVGSR
TAQAARAAGFADVTDCAGDVIALGTALKALPPGSRVLHAAGAERAGDLEGDLAPAGISLALAVLYRTLPADQLAPETLAA
LKSGAVAAALHYSARTVESLLEATARGDVTGPFLALRQLCLSHAVAAPLRALGATTEVSQTPDEDALLTLL

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23535; Mature: 23535

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVTRPQPGAGDTARRLAALGHDAIVDPMLRVAQTHAPLPTGDFTAIAFTSVNGVKAL
CEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHH
AAHAEKTRVRHLPAFAVGSRTAQAARAAGFADVTDCAGDVIALGTALKALPPGSRVLHAA
HHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHC
GAERAGDLEGDLAPAGISLALAVLYRTLPADQLAPETLAALKSGAVAAALHYSARTVESL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LEATARGDVTGPFLALRQLCLSHAVAAPLRALGATTEVSQTPDEDALLTLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC
>Mature Secondary Structure
MRLLVTRPQPGAGDTARRLAALGHDAIVDPMLRVAQTHAPLPTGDFTAIAFTSVNGVKAL
CEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHH
AAHAEKTRVRHLPAFAVGSRTAQAARAAGFADVTDCAGDVIALGTALKALPPGSRVLHAA
HHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHC
GAERAGDLEGDLAPAGISLALAVLYRTLPADQLAPETLAALKSGAVAAALHYSARTVESL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LEATARGDVTGPFLALRQLCLSHAVAAPLRALGATTEVSQTPDEDALLTLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA