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The map label for this gene is lysR [H]

Identifier: 158421870

GI number: 158421870

Start: 288774

End: 289805

Strand: Direct

Name: lysR [H]

Synonym: AZC_0246

Alternate gene names: 158421870

Gene position: 288774-289805 (Clockwise)

Preceding gene: 158421869

Following gene: 158421872

Centisome position: 5.38

GC content: 69.57

Gene sequence:

>1032_bases
TTGCCGTTTCCGTCCGGCGCCGGTTTGTGGTTTCTTCGGCGCGTGTGGTGCGGAGGAATGCGGGTGGCGGAGCCCTTCAA
GAATCTGGCGTGGGATGATTTCCGGCTCATCAAGGCGGTGGCCGATGCGCGCAGTCTGCCGGCGGCGGCGGTGCAGATGG
GGGTGAACCACTCCACCGTGTTCCGCCGCCTGAAGCAGATCGAGGAGGCGCTCGGCGTCGCCTTGTTCGTGCGCCACCGT
ACCGGCTATGCCCTCACCCCCGCCGGCGAGGAAGTGGTGGCGCTGGCAGAAAGGGTGGATGCGGACATCACCTCCGTCAC
CCGCAAGATCGCCGGGCGCGAACTGGCGCCGGCGGGCGAACTGCGCGTCACCACCAACGACAGCCTGCTGGTGCATCTGC
TGATGCCCATGCTTGCCCGCTTCCGCGAAGCCTGCCCGAGCGTGCGGCTGGACGTGGTGCTGGGCAATCAGGCGCTCAAT
CTCTCCAAGCGCGATGCCGATGTGGCGATCCGCGCCAGCGACACGCCGCCGGACAATCTGGTGGGCCGCCGCGTGGCGCG
CATCGGCTGGGCGCTCTATGGACTGGCACGGCGGTTTCCCAGCGCGGACGCTATCGCGCAGATGGACCCGGCGGCCGAGG
ACTGGGTGTCGCTGGGCGATGGCTTCGGCGGCATGAAGGTGGTCAAGGACACCCTTGCGCGCATCCCCCCGGAGCGGATC
GCCTATCGCGTCAACACGGTGTTCGGCCTCGCGGAGGCCATCGAGGCGGGGCTCGGCATCGGCTATGCGCCCTGCTTCAT
CGCCGATCCGCGCCCGGCCCTCGTGCGCCTCGCCCCGCCGGAGCCCGCCTATGCGGCCGATCTCTGGCTGCTCACCCATC
CCGACCTGCGCCACGCCGCCCGCGTGCGCGTGTTCCTCGATTTCATGGCCGGCGAGATCGCCAGATACCGCGTGTTTCTC
GAAGGCGCGGCCGAGGGGGGCGACGCCGTCGCGGAACAGGCACTGGCGTCAGAGGAGGCGGGGGAGGGTTAG

Upstream 100 bases:

>100_bases
TGTGACGCTCTCCGAGCTGATCGGCACCAAGGCGACGCCCCGCGCCGCCTGATCTCTTCCCGCCAGTCATCGGCACCGGG
CCGCGCCTTGAGCGCGGCCT

Downstream 100 bases:

>100_bases
GGCCGCTGGACCCCTGTTGAGGGCACGCCTCTGCCCCCTCCCTATCCCTCCCCCGCAAGCGGGAGAGGGGACTGCGTTCC
GGGGGGCGGAGAGCCTGCAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTVFRRLKQIEEALGVALFVRHR
TGYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGELRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALN
LSKRDADVAIRASDTPPDNLVGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERI
AYRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAARVRVFLDFMAGEIARYRVFL
EGAAEGGDAVAEQALASEEAGEG

Sequences:

>Translated_343_residues
MPFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTVFRRLKQIEEALGVALFVRHR
TGYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGELRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALN
LSKRDADVAIRASDTPPDNLVGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERI
AYRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAARVRVFLDFMAGEIARYRVFL
EGAAEGGDAVAEQALASEEAGEG
>Mature_342_residues
PFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTVFRRLKQIEEALGVALFVRHRT
GYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGELRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALNL
SKRDADVAIRASDTPPDNLVGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERIA
YRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAARVRVFLDFMAGEIARYRVFLE
GAAEGGDAVAEQALASEEAGEG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=152, Percent_Identity=30.9210526315789, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788706, Length=146, Percent_Identity=32.1917808219178, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37158; Mature: 37027

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTV
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
FRRLKQIEEALGVALFVRHRTGYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGE
HHHHHHHHHHHHHHHEEEECCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
LRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALNLSKRDADVAIRASDTPPDNL
EEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCHHH
VGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERI
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
AYRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCCHHEEEEEECCCHHHHH
RVRVFLDFMAGEIARYRVFLEGAAEGGDAVAEQALASEEAGEG
HHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTV
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHH
FRRLKQIEEALGVALFVRHRTGYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGE
HHHHHHHHHHHHHHHEEEECCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
LRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALNLSKRDADVAIRASDTPPDNL
EEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCHHH
VGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERI
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCHHHH
AYRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEECCCCCCCHHEEEEEECCCHHHHH
RVRVFLDFMAGEIARYRVFLEGAAEGGDAVAEQALASEEAGEG
HHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]