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The map label for this gene is dapL [H]

Identifier: 158421721

GI number: 158421721

Start: 114063

End: 115271

Strand: Reverse

Name: dapL [H]

Synonym: AZC_0097

Alternate gene names: 158421721

Gene position: 115271-114063 (Counterclockwise)

Preceding gene: 158421722

Following gene: 158421720

Centisome position: 2.15

GC content: 70.14

Gene sequence:

>1209_bases
ATGCCCGACACCATGCCCACATCCGCGACCACACCCTCCGATGACCGCCGGTCGCCCTTCGTGCGCCTCGCGGATCTGCT
CGCCGGTATCGAGCCTGGCCGTCCACCGCTGATCGCGGCCGTGGGCGAACCGCAGCATGCGTTTGCCGACTTCGTGGCGT
CCGCCCTCCACGACACGCTGGAAGGCTTCGGCCGCTATCCGCGCCAGGAGGGCACGCCGGAGTTCCGCGCCGCCGTCGCT
GAATGGCTGGGCAAGCGCTACACCCTCGCCCGCCCCGTCGACCCGGATCGGGAAGTGCTGGCGCTGAACGGCTCGCGCGA
GGGCCTCGTGAGCGCCACCTTCATCGCCCGCCGCCGGGGGCCGGAGCGCAAGGGCGCGCCCATCGTCCTCGTGCCGAACC
CGCTCTATGCCGCCTACCGCGCCGGTGCGGAACTCGCCGGCTGCGAAGTGGTGCCCATGCCCACCACCCGCGAGAGCGGC
TGGCTGCCCGATCTCGACGCGCTGGACCCGGCGCTGCTCGACCGGGCCGTGGTGCTGTTCCTGGCCTCGCCGGCCAATCC
GCAGGGCGCCGTCGCCTCGCGCGAATATCTCACCCGGCTCATGGAGATGACCCGTCGCCACGGCGTCTATCTGTTTGCCG
ACGAATGCTATTCGGAAATCTATCTTGAGGAAGAGAAGCCCACGGGCGTCCTCGAGGTGGCCGAGGGCAATTTCTCCGGC
ATCCTCTCCTTCAACTCGCTGTCCAAGCGCTCGTCGCTGCCGGGCCTGCGCGTCGGCTTCGTGGCCGGCGACCCGGTGTT
CCTGCGCGACTTTCTCGCCTTCCGCGGCATCGCCTGCCCGCAGGTCCCCGAGCCGCTCCAGGCGGTCGCCGTGGCCGCGC
TTCAGGACGAGGCGCACGTGATCGCCTCGCGCATGCTCTACAAGTCCAAGTTCGACATCGCCGACCGCCTCCTCCACAAG
CGCTTCGGATACAAGCGGCCGGACGGCGGCTTCTTCCTGTGGCTCGACGTCTCGGACGCCGGCGGTGGCGAGGCGGCCGC
CCTGCGCCTGTGGAAGGAGCAGGGGCTGCGCACGGTTCCGGGCGGCTATCTCGCCTCCCGCGACCTCACCGGCCACAATC
CCGGCGAGCCCTACCTGCGCGTCGCCATGGTCCACGATCTCACCACGAGCGAAGAGGTGCTGAACCGCCTCATCGCCGGC
CTGTCCTGA

Upstream 100 bases:

>100_bases
TCTCCGATCGGACCGCCCGGTCTGATCGGAGCGTGCCTAACGAACATTGGCCGGGTTAGGCCCCTCTTAACCTTGCCTGA
AGCACTCTCTGGCGAACCTG

Downstream 100 bases:

>100_bases
GGAGAGCGCGCTGATGCCCGTCCGCCGTCGTTCCGCGTCTGCACTGACGATGCGCGCGCATGGCGGGGGCATGGACTTCA
TTCCGGAGAGCGTCCGCCTC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTLEGFGRYPRQEGTPEFRAAVA
EWLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRGPERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESG
WLPDLDALDPALLDRAVVLFLASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSG
ILSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHVIASRMLYKSKFDIADRLLHK
RFGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVPGGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAG
LS

Sequences:

>Translated_402_residues
MPDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTLEGFGRYPRQEGTPEFRAAVA
EWLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRGPERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESG
WLPDLDALDPALLDRAVVLFLASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSG
ILSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHVIASRMLYKSKFDIADRLLHK
RFGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVPGGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAG
LS
>Mature_401_residues
PDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTLEGFGRYPRQEGTPEFRAAVAE
WLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRGPERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESGW
LPDLDALDPALLDRAVVLFLASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSGI
LSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHVIASRMLYKSKFDIADRLLHKR
FGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVPGGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAGL
S

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=383, Percent_Identity=23.4986945169713, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI169881279, Length=383, Percent_Identity=23.4986945169713, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4507369, Length=261, Percent_Identity=23.7547892720307, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788722, Length=301, Percent_Identity=25.2491694352159, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788627, Length=160, Percent_Identity=30.625, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790797, Length=222, Percent_Identity=25.2252252252252, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=300, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=300, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=258, Percent_Identity=25.5813953488372, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=177, Percent_Identity=27.1186440677966, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323118, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28573069, Length=331, Percent_Identity=23.2628398791541, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24646114, Length=331, Percent_Identity=23.2628398791541, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573067, Length=331, Percent_Identity=23.2628398791541, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573065, Length=331, Percent_Identity=23.2628398791541, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859735, Length=284, Percent_Identity=24.2957746478873, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43838; Mature: 43707

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EGFGRYPRQEGTPEFRAAVAEWLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRG
HHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHCC
PERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESGWLPDLDALDPALLDRAVVLF
CCCCCCCEEEECCCHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHEEE
LASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSG
EECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHEECCCCCCCEEEEECCCCEE
ILSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHV
EEEECHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IASRMLYKSKFDIADRLLHKRFGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCC
GGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAGLS
CCCEECCCCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
PDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EGFGRYPRQEGTPEFRAAVAEWLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRG
HHHHCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHCC
PERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESGWLPDLDALDPALLDRAVVLF
CCCCCCCEEEECCCHHHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHCCHHHHHHHHEEE
LASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSG
EECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHEECCCCCCCEEEEECCCCEE
ILSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHV
EEEECHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
IASRMLYKSKFDIADRLLHKRFGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCC
GGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAGLS
CCCEECCCCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA