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The map label for this gene is ftsK [H]

Identifier: 158421720

GI number: 158421720

Start: 111605

End: 114049

Strand: Reverse

Name: ftsK [H]

Synonym: AZC_0096

Alternate gene names: 158421720

Gene position: 114049-111605 (Counterclockwise)

Preceding gene: 158421721

Following gene: 158421719

Centisome position: 2.12

GC content: 69.98

Gene sequence:

>2445_bases
ATGCCCGTCCGCCGTCGTTCCGCGTCTGCACTGACGATGCGCGCGCATGGCGGGGGCATGGACTTCATTCCGGAGAGCGT
CCGCCTCGCCATCCGCCGCCGGTCTTCCGAGATCTGCGGCGTGGTGGTGCTTGGCGCCGCCGCCTTCGCGCTCCTGTCGC
TGATGACCTGGTCGGCCTCCGACCCGAGCCTGTCCAACGCCACCAACGCCAAGGTGAGCAACCTGCTGGGCCGGCCCGGC
GCGGTGCTGGCCGATCTGCTGATGCAGCTCTTCGGCCTCGCCTCGCTCGCCATCATCCTGCCGCTCGCCATCTGGGGCTG
GCGGCTGCTGACCTTCCGCCCGCTCAAGGGCGAGAAGCTGCGCATCGTCGCCCTCACCTTCGGGGCGCTCGGCACCAGCG
CCTTCCTCGGCGCTTTGCCGGCCTTCGGCGCCTGGCCCATGCCCACCGGCCTCGGCGGCGTGATGGGCGATCTCATTCCG
CGCCTGTTCCTGCTGCTCACCGGCAGCTTCGGCTCCTTCCTCGAATCCGCCGTCACCGGCCTTCTCGGTGGCACGCTGGC
GCTCGCCGGCCTCTATGTGGCCTGCCGCCCCAATCCGCCGGAAGACGAGGCGGAAGAGGTGGACGAGCCCTACGACGCCG
AAGAGGTGGAGCGCGGGGCGATGATCTCGCTGGGCGCCCTCACCCACACCTTCCTCTCGCTCAAGGCCCGCCTCTCTGGG
CGCCGCCGGTCGCGCACCTATGTGCCGAGCACGCCGGCCGCGCGCGGGCCGGTCGTCGCCGGCGGCCGCATGGAGCCGCG
CTTCGCGGCGAGCGCCCCCGCGCCCGTGGTGCCCGAAGCGCCCGTGCCCGACGAAGAGACCTATGTGGCGCCGCCCCCGC
GCAGCCGCAGCCACGGCAAGCGCGTGCCGGTGGCCATGCCCGGCCGGCGCGGCTTCTACGAACTGCCCGACCTCGGCCTC
CTCGCCGCGCCTCCCCCCTCCAAGGGGCCGACCATGTCGGCGGAAGCTCTGCAGGACACCGCCAAGCTGCTTGAAAGCAC
GCTGGAGGACTTCGGCGTGCGCGGCGAGATCGTGCAGGTCCGCCCCGGCCCCGTGGTGACGCTCTACGAGCTGGAGCCGG
CGCCCGGCATCAAGTCCTCCCGCGTCATCGGGCTGGCCGACGACATCGCCCGCTCCATGAGCGCCATCTCGGCCCGCGTC
GCCGTGGTGCCCGGCCGCAATGCCATCGGCATCGAGCTGCCCAACCAGCGCCGCGACAAGGTCCTGCTGCGCGAACTGCT
CTCCACCAAGGACTTCTCCGAGAACGGCCAGAAGCTCGCCATCGCGCTCGGCAAGACCATCGGCGGCGAGCCGGTGATCG
TCGATCTCGCCCGCATGCCGCACCTGCTGGTGGCCGGCACCACCGGCTCGGGCAAGTCGGTGGCCATCAACACCATGATC
CTGTCGCTGCTCTACCGGCTGCCGCCGGATCAGTGCCGCCTGATCATGGTGGACCCCAAGATGCTGGAACTCTCCGTCTA
TGACGGCATCCCGCACCTGCTCGCCCCCGTCGTCACCGACCCCAAGAAGGCGGTCGTGGCGCTCAAGTGGGCGGTCCGGG
AGATGGAGGACCGCTACAAGAAGATGTCCAAGCTCGGCGTGCGCAACATCGACGGCTTCAATGCCCGTGTGGCGGATGCC
CAGAAGCGCGGCGAATCGCTGGCCCGCACCGTGCAGACGGGCTTCGACCACGAGACGGGCGAAGCCATCTACGAGCGCGA
GGAGATGGAGCTGGGGCCGCTGCCCTACATCGTCATCATCGTGGACGAGATGGCGGACCTGATGCTGACCGCCGGCAAGG
ACATCGAGGGCGCCATCCAGCGGCTCGCCCAGATGGCCCGCGCCGCCGGCATCCACCTCGTGATGGCGACCCAGCGCCCG
TCCGTGGACGTCATCACCGGCACCATCAAGGCCAATTTCCCCACCCGCATTTCCTTCCAGGTCACGTCGAAGATCGACAG
CCGCACCATCCTCGGCGAGATGGGCGCCGAGCAGCTCCTCGGCCAGGGCGACATGCTCTACATGGCCGGCGGCGGCCGCA
TCAGCCGCGTGCACGGCCCGTTCGTGTCGGACGAGGAAGTCGAGCACGTGGTGCGCCACCTCAAGGCGCAGGGCGCGCCG
GACTATGTGGACGCCGTGACCGCCGACTTCGACGAGGATGGCGACGAGGACGGCGCCGTGTTCGACAAGAGCGGCATGGG
CGAGGGCGGCGACATCTACTCGCAGGCCGTCGCCGTGGTGCTCCGGGACAAGAAGTGCTCCACCTCCTACATCCAGCGGC
GTCTCCAGATCGGCTACAACCGCGCGGCCTCGCTGGTGGAACGGATGGAGAAGGAAGGCCTCGTCGGCCCCGCCAACCAT
GCCGGCAAGCGCGAGATCCTCGTCACCGACGAGGCCGCCGAATAG

Upstream 100 bases:

>100_bases
GGCGAGCCCTACCTGCGCGTCGCCATGGTCCACGATCTCACCACGAGCGAAGAGGTGCTGAACCGCCTCATCGCCGGCCT
GTCCTGAGGAGAGCGCGCTG

Downstream 100 bases:

>100_bases
GCGCCCGGCCCGCTTCCCCGACACAGGATCGCCATAGGGAATGGGTAGCCAGCTCAGGCTGCCACCGCCGGAACCGGCTG
CCCGGCCGATGAAAAGCGGG

Product: FtsK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 814; Mature: 813

Protein sequence:

>814_residues
MPVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSASDPSLSNATNAKVSNLLGRPG
AVLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKLRIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIP
RLFLLLTGSFGSFLESAVTGLLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSG
RRRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGKRVPVAMPGRRGFYELPDLGL
LAAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARV
AVVPGRNAIGIELPNQRRDKVLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMI
LSLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYKKMSKLGVRNIDGFNARVADA
QKRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVIIVDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRP
SVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAP
DYVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYNRAASLVERMEKEGLVGPANH
AGKREILVTDEAAE

Sequences:

>Translated_814_residues
MPVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSASDPSLSNATNAKVSNLLGRPG
AVLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKLRIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIP
RLFLLLTGSFGSFLESAVTGLLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSG
RRRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGKRVPVAMPGRRGFYELPDLGL
LAAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARV
AVVPGRNAIGIELPNQRRDKVLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMI
LSLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYKKMSKLGVRNIDGFNARVADA
QKRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVIIVDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRP
SVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAP
DYVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYNRAASLVERMEKEGLVGPANH
AGKREILVTDEAAE
>Mature_813_residues
PVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSASDPSLSNATNAKVSNLLGRPGA
VLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKLRIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIPR
LFLLLTGSFGSFLESAVTGLLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSGR
RRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGKRVPVAMPGRRGFYELPDLGLL
AAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARVA
VVPGRNAIGIELPNQRRDKVLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMIL
SLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYKKMSKLGVRNIDGFNARVADAQ
KRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVIIVDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRPS
VDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAPD
YVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYNRAASLVERMEKEGLVGPANHA
GKREILVTDEAAE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=495, Percent_Identity=52.9292929292929, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 87215; Mature: 87084

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSAS
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPSLSNATNAKVSNLLGRPGAVLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCE
RIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIPRLFLLLTGSFGSFLESAVTG
EEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSG
HHHHHHHHHCEEEEECCCCCCCHHHHCCCCCCHHHHCCCCEEEHHHHHHHHHHHHHHHCC
RRRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGK
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
RVPVAMPGRRGFYELPDLGLLAAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQV
CCCEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
RPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARVAVVPGRNAIGIELPNQRRDK
CCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEEEEEECCCCEEEEECCCCHHHH
VLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMI
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCEEEEEECCCCCCEEHHHHHH
LSLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYK
HHHHHHCCCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KMSKLGVRNIDGFNARVADAQKRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVII
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEE
VDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRPSVDVITGTIKANFPTRISFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEE
VTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAP
EECCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
DYVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYN
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHH
RAASLVERMEKEGLVGPANHAGKREILVTDEAAE
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSAS
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
DPSLSNATNAKVSNLLGRPGAVLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCE
RIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIPRLFLLLTGSFGSFLESAVTG
EEEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSG
HHHHHHHHHCEEEEECCCCCCCHHHHCCCCCCHHHHCCCCEEEHHHHHHHHHHHHHHHCC
RRRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGK
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
RVPVAMPGRRGFYELPDLGLLAAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQV
CCCEECCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
RPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARVAVVPGRNAIGIELPNQRRDK
CCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHHEEEEEECCCCEEEEECCCCHHHH
VLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMI
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEHHHCCEEEEEECCCCCCEEHHHHHH
LSLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYK
HHHHHHCCCCCEEEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KMSKLGVRNIDGFNARVADAQKRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVII
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEE
VDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRPSVDVITGTIKANFPTRISFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEE
VTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAP
EECCCCCHHHHHHHCHHHHHCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
DYVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYN
HHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHH
RAASLVERMEKEGLVGPANHAGKREILVTDEAAE
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]