Click here to switch to the map view.

The map label for this gene is galE [C]

Identifier: 158338849

GI number: 158338849

Start: 5842516

End: 5843529

Strand: Direct

Name: galE [C]

Synonym: AM1_5762

Alternate gene names: 158338849

Gene position: 5842516-5843529 (Clockwise)

Preceding gene: 158338848

Following gene: 158338850

Centisome position: 89.83

GC content: 42.9

Gene sequence:

>1014_bases
ATGGAATTATCAGGCAAGCGAGTATTAGTTATTGGGGGAGCAGGTTTGATTGGCTCCCATACTGTTGATACTCTTCTTAA
AGAGGATGTTGAAGAAGTACGAATTTTTGATAATTTTACTCGAGGCAGCCGTGAAAACCTCTCAGAAGCACTCAAAGATC
CACGATGTAATATTTTTCCCCTAGGTGGGGAGTTGATGCATCGCGACCTTTTGGATGCTGCAATGAAAGGCATTGATGGG
GTTTTCCATTTTGCGGCTATGTGGTTATTGCATTGTTACAACTTTCCCAGATCTGCCTTTGAAGTCAACATTGGTGGAAC
CTTTAACGTATTGGAAGCTTGCATCAACAATGGTGTTCAGCGTTTAGTGTTCTCATCTTCTGCTTCGGTTTATGGGGATG
CCGTTACGGAACCAATGACCGAAGATCATCCTTATAACAATCAAACCTTTTACGGAGCAACAAAGATTGCAGGGGAGCAC
ATGTGTCATTCCCTCTATCACCGCTATAAAGACACTGATCAACATTTTGACTATGTTGGTTTGCGCTACATGAATGTCTT
TGGTCCGCGGCAAGACTATCAAGGGACCTATATTGCAGTCATTATGAAAATTCTCGATCGGTTAGATCAGGGATTGCCAC
CCATTATCTATGGTGATGGATCTCAAGCGTACGATTTTGTTTACGTTGAAGACTGTGCTCAAGCTAATGTTTGCGCGATG
AAGGCTCAGGCCACTGATGCTTTTTACAATGTCGGTACTGGTATTAAAACCTCATTAAAAGAGTTAACGGAGTTGATCCT
AGAGATCACAGGTTCTTCACAACAAATTCAGTACGAGCCAAGTGGACAAACGTTTGTGAAAAATCGAGTGGGATGTCCCC
TGAAGGCAGAAGAAGAAATCAGCTTCAAAGCTAAAGTCCAACTTCGCGAAGGATTAGAGCGGTTAATTGTTTGGCGGAAC
CAGCATAAAGAGATTGTGGCCCAAAAACGAGAACATGCAGGAGTATTGGGATGA

Upstream 100 bases:

>100_bases
AATTAATCAGCAATGGAAAAACAGGTAAAAATTAGCCTGCATTCAATCTGTTTAAGTCCTCTTCAAATATCACTAAATGA
TGTAAAGGAAAACAATATCA

Downstream 100 bases:

>100_bases
CAGAGCACCGCAATATTCCCATCTCACTACCATCAACGGGTGAAGAAGAATGGTTAGCGTTGAAAGAGCCTCTACTGTCT
GGTTGGTTAACTCAAGGCCC

Product: NAD dependent epimerase/dehydratase protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MELSGKRVLVIGGAGLIGSHTVDTLLKEDVEEVRIFDNFTRGSRENLSEALKDPRCNIFPLGGELMHRDLLDAAMKGIDG
VFHFAAMWLLHCYNFPRSAFEVNIGGTFNVLEACINNGVQRLVFSSSASVYGDAVTEPMTEDHPYNNQTFYGATKIAGEH
MCHSLYHRYKDTDQHFDYVGLRYMNVFGPRQDYQGTYIAVIMKILDRLDQGLPPIIYGDGSQAYDFVYVEDCAQANVCAM
KAQATDAFYNVGTGIKTSLKELTELILEITGSSQQIQYEPSGQTFVKNRVGCPLKAEEEISFKAKVQLREGLERLIVWRN
QHKEIVAQKREHAGVLG

Sequences:

>Translated_337_residues
MELSGKRVLVIGGAGLIGSHTVDTLLKEDVEEVRIFDNFTRGSRENLSEALKDPRCNIFPLGGELMHRDLLDAAMKGIDG
VFHFAAMWLLHCYNFPRSAFEVNIGGTFNVLEACINNGVQRLVFSSSASVYGDAVTEPMTEDHPYNNQTFYGATKIAGEH
MCHSLYHRYKDTDQHFDYVGLRYMNVFGPRQDYQGTYIAVIMKILDRLDQGLPPIIYGDGSQAYDFVYVEDCAQANVCAM
KAQATDAFYNVGTGIKTSLKELTELILEITGSSQQIQYEPSGQTFVKNRVGCPLKAEEEISFKAKVQLREGLERLIVWRN
QHKEIVAQKREHAGVLG
>Mature_337_residues
MELSGKRVLVIGGAGLIGSHTVDTLLKEDVEEVRIFDNFTRGSRENLSEALKDPRCNIFPLGGELMHRDLLDAAMKGIDG
VFHFAAMWLLHCYNFPRSAFEVNIGGTFNVLEACINNGVQRLVFSSSASVYGDAVTEPMTEDHPYNNQTFYGATKIAGEH
MCHSLYHRYKDTDQHFDYVGLRYMNVFGPRQDYQGTYIAVIMKILDRLDQGLPPIIYGDGSQAYDFVYVEDCAQANVCAM
KAQATDAFYNVGTGIKTSLKELTELILEITGSSQQIQYEPSGQTFVKNRVGCPLKAEEEISFKAKVQLREGLERLIVWRN
QHKEIVAQKREHAGVLG

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=317, Percent_Identity=28.7066246056782, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI7657641, Length=334, Percent_Identity=29.940119760479, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56237023, Length=349, Percent_Identity=29.512893982808, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI56118217, Length=349, Percent_Identity=29.512893982808, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI189083684, Length=349, Percent_Identity=29.512893982808, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI193211614, Length=252, Percent_Identity=30.1587301587302, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI8393516, Length=252, Percent_Identity=30.1587301587302, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786974, Length=352, Percent_Identity=27.5568181818182, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790049, Length=330, Percent_Identity=24.5454545454545, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788365, Length=301, Percent_Identity=24.9169435215947, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=25.2124645892351, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788353, Length=356, Percent_Identity=26.685393258427, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=25.3086419753086, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17568069, Length=288, Percent_Identity=30.2083333333333, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=354, Percent_Identity=27.1186440677966, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=25.5384615384615, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19923002, Length=365, Percent_Identity=28.4931506849315, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37780; Mature: 37780

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSGKRVLVIGGAGLIGSHTVDTLLKEDVEEVRIFDNFTRGSRENLSEALKDPRCNIFP
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LGGELMHRDLLDAAMKGIDGVFHFAAMWLLHCYNFPRSAFEVNIGGTFNVLEACINNGVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCHH
RLVFSSSASVYGDAVTEPMTEDHPYNNQTFYGATKIAGEHMCHSLYHRYKDTDQHFDYVG
HHHHCCCCCCCCHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LRYMNVFGPRQDYQGTYIAVIMKILDRLDQGLPPIIYGDGSQAYDFVYVEDCAQANVCAM
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCEEE
KAQATDAFYNVGTGIKTSLKELTELILEITGSSQQIQYEPSGQTFVKNRVGCPLKAEEEI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCCCC
SFKAKVQLREGLERLIVWRNQHKEIVAQKREHAGVLG
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MELSGKRVLVIGGAGLIGSHTVDTLLKEDVEEVRIFDNFTRGSRENLSEALKDPRCNIFP
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEE
LGGELMHRDLLDAAMKGIDGVFHFAAMWLLHCYNFPRSAFEVNIGGTFNVLEACINNGVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCHH
RLVFSSSASVYGDAVTEPMTEDHPYNNQTFYGATKIAGEHMCHSLYHRYKDTDQHFDYVG
HHHHCCCCCCCCHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LRYMNVFGPRQDYQGTYIAVIMKILDRLDQGLPPIIYGDGSQAYDFVYVEDCAQANVCAM
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCEEE
KAQATDAFYNVGTGIKTSLKELTELILEITGSSQQIQYEPSGQTFVKNRVGCPLKAEEEI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCCCCCCCCCC
SFKAKVQLREGLERLIVWRNQHKEIVAQKREHAGVLG
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]