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The map label for this gene is luxQ [H]

Identifier: 158338730

GI number: 158338730

Start: 5698390

End: 5700807

Strand: Reverse

Name: luxQ [H]

Synonym: AM1_5638

Alternate gene names: 158338730

Gene position: 5700807-5698390 (Counterclockwise)

Preceding gene: 158338733

Following gene: 158338729

Centisome position: 87.65

GC content: 47.73

Gene sequence:

>2418_bases
TTGAAGTCTGAGATTTGGCATAAACTTCGTCAACCATTAGCCCCACTGAAGCTTGTGGCGCTCCCCAGCTTACTTATACT
GGGCCTAATCCTCGGTGGACGATGGGCAGGAACCTTCCAATCCTGGGAATTGCAAGTCTTAGATCTCTTTCTGAAATATC
AACCGACAGAAACCCAAGACAAACGCATTCTGTTGGTCACGATTGATGAGGATAGTATTCGCTCGATTGGCCGCTATCCC
ATTCCCGATCAATACCTCGCCCAGTCGCTCAACATTCTTCAAGAGCATGAGCCTAGAGCAATTGGTCTGGATTTATTCCG
AGATATCCCCGTAGAACCGGGTTCAGCAGACTTGGCCACCGCCTTTCAGGAGATGGAAAATCTATTTGGTATCGATAAAA
TTCTGGATGAGAATAAGAAAGAACTGGATGAGAACCAATCGGAACGAGTGAATCCTCCCCCCGGCTTACCCCTAGACCGA
GTTGGATTTGCTGATGCCCCTGTCGATCTGGACGGTAGCCAACGTCGGGTCATGCTGGGAACTCAAACGAAAAAACAAGT
CTTCCGATACTCCCTAGCATTACTCCTAGCCGAGAAATTTCTAATTGCCCAAAATATCCATCTAGATAATGGCATCAATG
ATCCCGTAGCCATGAGATTTAAGTCTGCGGAGATTCCTCGAATTCGACCTAATTTTGGGGGCTATATTCGCACCAATACT
GGGAATGCAGATGTCCAAATGCTGCTCAATTTTCGCAACCATCCCAAAGCATTTGAGACTGTCTCATTTCATAAATTACT
ATCAGGCAATGTTTCACCGGATTCAGTCAGAAATCGTATCGTCCTGATTGGCATCACCACCCCTAGCTTCCAGGACTATT
CTCCCGCTGCCATTCCCTCCATCATCTCTCCGAAAGCAAACTGGGTCTATGGCATTGAGATACATGCTCATGCCATTAGT
CAAATTCTGAGTGCAACTTTAGATCAACGACCGCTGATCAGTACTTGGCCAGATTGGATAGAGTACCTCTGTATTTTGGG
CGGCGGTCTAGTGGGCATCATTGTTGCCGCCTATATTCACTCACCTCGGTATACGATACTTGCGATCGCACTCTCCGCAT
TACTGGTATCCGGCATCAGCTATCTAGCACTACTTTGGGGATGGTGGCTACCCGTGGTCCCAACCCTAGCCAGCTTTCTG
CTAATCAGCCTCAGTCTAGATGCCTTCTATCAGTACGATCGCTTCATCCAAACCAAGGTCAAAGCCCAACAACAGACCCT
TCGCATCCTGGAACAGGCCAAAACCGATCTGGAAATTCAGGTTGCCCAACGAACCTCCGAACTTCAGCAATCAAATCTAG
AGCTCAGCCAAGCCAAAGAAGCGGCCGAAATGGCCAGTCGGGCCAAGGGAAAATTTCTCGCCAAAATGAGCCATGAATTA
CGCACGCCCCTCAATGCCATTCTGGGGTTTAGCCAAATGATGGCCCAAGACACCACTCTCTCTGAAGCCAATCACAAACG
CAATCGCTTAATTAACCAAAGTGGCGAACACTTATTAGGACTGATCAACGACATTTTATCTCTAGCCAAACTAGAGTCAG
GAAAACAAGAACTGCGAGAAGGTCCCTTCCAACTCAGTACCTTACTGGAGACCGTAGAAGGCATCTTTCGACTTCGAATC
GAACAAAAAGGATTAGCCTTTCGGGTTAAAGCCACCCCCGATCTCCCACCCTATTTATTCGGAGATGCCCAGAAACTCCG
ACAAGTCCTCATCAACTTGTTGAGCAATGCCCTTAAATTCACCCCGGCCGGACACATCTTTCTCCGCATAGGGAGCATAC
CCACACCAGCAGGTTTGACATTACGGTTTGAAATTGAAGACACAGGCGAAGGAATTGCCGCTTCTGAACTGCACAAATTG
TTTGTTCCTTTTGAACAAACTGAAAGTGGAGAGAAATCGAAAGCTGGCACAGGACTTGGTTTACCCATTAGTCAACAATT
CGCTCAGCTAATGGGTGGGGATATCAAGGTATCCAGCCAAGTCGGGCAAGGGACAACCTTCACCTTTACGGCCCAAGTCA
CCATCGCAGAGTCCGACAGTGACGCCAGTTTACAAAATATTGCAGACGGGGTGGCTCCCCCCCCACCACCAAATGATAGG
GTTGAACCAGAAGCACTCCCCTCAGCCGTCATTAGTTCAGAGATCATTGATCAAGCCTTAGGATCGATGTCCGCCAACTG
GTTAGATGAACTGCACCATGCTGCCCTCCGACTCAAGGGCAAACAAGTGATCCAGCTTTTATCCGAAATGCCACCGGAAT
ATGAATCAGCCTCCCAATATTTGATTGAGCTAGCCGAGAACTATGAATATGCTCATATTACTGAAGTTACGACCAAATTA
ACGCAAGACAAACCTTAA

Upstream 100 bases:

>100_bases
GAGCGTTCAGGTTGATCTTCAAAACGAAATCTAGACCAGAATTCGAGGATTGCAGGGGGAATGGGTTCATATCACATATC
ACGAATTAAGGGGATAAGGA

Downstream 100 bases:

>100_bases
GGTCCGTTTCTATGAGCGACATCGATCATTCCAGTGAACCCATCTTAGAATTTGCAGAAAACTTAATCCTGCAAAAAACG
GACACCTACTGCAGTGAACT

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MKSEIWHKLRQPLAPLKLVALPSLLILGLILGGRWAGTFQSWELQVLDLFLKYQPTETQDKRILLVTIDEDSIRSIGRYP
IPDQYLAQSLNILQEHEPRAIGLDLFRDIPVEPGSADLATAFQEMENLFGIDKILDENKKELDENQSERVNPPPGLPLDR
VGFADAPVDLDGSQRRVMLGTQTKKQVFRYSLALLLAEKFLIAQNIHLDNGINDPVAMRFKSAEIPRIRPNFGGYIRTNT
GNADVQMLLNFRNHPKAFETVSFHKLLSGNVSPDSVRNRIVLIGITTPSFQDYSPAAIPSIISPKANWVYGIEIHAHAIS
QILSATLDQRPLISTWPDWIEYLCILGGGLVGIIVAAYIHSPRYTILAIALSALLVSGISYLALLWGWWLPVVPTLASFL
LISLSLDAFYQYDRFIQTKVKAQQQTLRILEQAKTDLEIQVAQRTSELQQSNLELSQAKEAAEMASRAKGKFLAKMSHEL
RTPLNAILGFSQMMAQDTTLSEANHKRNRLINQSGEHLLGLINDILSLAKLESGKQELREGPFQLSTLLETVEGIFRLRI
EQKGLAFRVKATPDLPPYLFGDAQKLRQVLINLLSNALKFTPAGHIFLRIGSIPTPAGLTLRFEIEDTGEGIAASELHKL
FVPFEQTESGEKSKAGTGLGLPISQQFAQLMGGDIKVSSQVGQGTTFTFTAQVTIAESDSDASLQNIADGVAPPPPPNDR
VEPEALPSAVISSEIIDQALGSMSANWLDELHHAALRLKGKQVIQLLSEMPPEYESASQYLIELAENYEYAHITEVTTKL
TQDKP

Sequences:

>Translated_805_residues
MKSEIWHKLRQPLAPLKLVALPSLLILGLILGGRWAGTFQSWELQVLDLFLKYQPTETQDKRILLVTIDEDSIRSIGRYP
IPDQYLAQSLNILQEHEPRAIGLDLFRDIPVEPGSADLATAFQEMENLFGIDKILDENKKELDENQSERVNPPPGLPLDR
VGFADAPVDLDGSQRRVMLGTQTKKQVFRYSLALLLAEKFLIAQNIHLDNGINDPVAMRFKSAEIPRIRPNFGGYIRTNT
GNADVQMLLNFRNHPKAFETVSFHKLLSGNVSPDSVRNRIVLIGITTPSFQDYSPAAIPSIISPKANWVYGIEIHAHAIS
QILSATLDQRPLISTWPDWIEYLCILGGGLVGIIVAAYIHSPRYTILAIALSALLVSGISYLALLWGWWLPVVPTLASFL
LISLSLDAFYQYDRFIQTKVKAQQQTLRILEQAKTDLEIQVAQRTSELQQSNLELSQAKEAAEMASRAKGKFLAKMSHEL
RTPLNAILGFSQMMAQDTTLSEANHKRNRLINQSGEHLLGLINDILSLAKLESGKQELREGPFQLSTLLETVEGIFRLRI
EQKGLAFRVKATPDLPPYLFGDAQKLRQVLINLLSNALKFTPAGHIFLRIGSIPTPAGLTLRFEIEDTGEGIAASELHKL
FVPFEQTESGEKSKAGTGLGLPISQQFAQLMGGDIKVSSQVGQGTTFTFTAQVTIAESDSDASLQNIADGVAPPPPPNDR
VEPEALPSAVISSEIIDQALGSMSANWLDELHHAALRLKGKQVIQLLSEMPPEYESASQYLIELAENYEYAHITEVTTKL
TQDKP
>Mature_805_residues
MKSEIWHKLRQPLAPLKLVALPSLLILGLILGGRWAGTFQSWELQVLDLFLKYQPTETQDKRILLVTIDEDSIRSIGRYP
IPDQYLAQSLNILQEHEPRAIGLDLFRDIPVEPGSADLATAFQEMENLFGIDKILDENKKELDENQSERVNPPPGLPLDR
VGFADAPVDLDGSQRRVMLGTQTKKQVFRYSLALLLAEKFLIAQNIHLDNGINDPVAMRFKSAEIPRIRPNFGGYIRTNT
GNADVQMLLNFRNHPKAFETVSFHKLLSGNVSPDSVRNRIVLIGITTPSFQDYSPAAIPSIISPKANWVYGIEIHAHAIS
QILSATLDQRPLISTWPDWIEYLCILGGGLVGIIVAAYIHSPRYTILAIALSALLVSGISYLALLWGWWLPVVPTLASFL
LISLSLDAFYQYDRFIQTKVKAQQQTLRILEQAKTDLEIQVAQRTSELQQSNLELSQAKEAAEMASRAKGKFLAKMSHEL
RTPLNAILGFSQMMAQDTTLSEANHKRNRLINQSGEHLLGLINDILSLAKLESGKQELREGPFQLSTLLETVEGIFRLRI
EQKGLAFRVKATPDLPPYLFGDAQKLRQVLINLLSNALKFTPAGHIFLRIGSIPTPAGLTLRFEIEDTGEGIAASELHKL
FVPFEQTESGEKSKAGTGLGLPISQQFAQLMGGDIKVSSQVGQGTTFTFTAQVTIAESDSDASLQNIADGVAPPPPPNDR
VEPEALPSAVISSEIIDQALGSMSANWLDELHHAALRLKGKQVIQLLSEMPPEYESASQYLIELAENYEYAHITEVTTKL
TQDKP

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=40.0793650793651, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081816, Length=264, Percent_Identity=40.530303030303, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=37.0229007633588, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=34.5454545454545, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI1788713, Length=292, Percent_Identity=33.2191780821918, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1786600, Length=296, Percent_Identity=27.3648648648649, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=28.0172413793103, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=30.4878048780488, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=31.0483870967742, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1787894, Length=250, Percent_Identity=26.8, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=26.3392857142857, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786783, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788279, Length=210, Percent_Identity=27.6190476190476, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=147, Percent_Identity=34.0136054421769, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89253; Mature: 89253

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEIWHKLRQPLAPLKLVALPSLLILGLILGGRWAGTFQSWELQVLDLFLKYQPTETQD
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
KRILLVTIDEDSIRSIGRYPIPDQYLAQSLNILQEHEPRAIGLDLFRDIPVEPGSADLAT
CEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCCHHHHH
AFQEMENLFGIDKILDENKKELDENQSERVNPPPGLPLDRVGFADAPVDLDGSQRRVMLG
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
TQTKKQVFRYSLALLLAEKFLIAQNIHLDNGINDPVAMRFKSAEIPRIRPNFGGYIRTNT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCCCCCCCCCCCEEEECC
GNADVQMLLNFRNHPKAFETVSFHKLLSGNVSPDSVRNRIVLIGITTPSFQDYSPAAIPS
CCCCHHHEEECCCCCCHHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCCH
IISPKANWVYGIEIHAHAISQILSATLDQRPLISTWPDWIEYLCILGGGLVGIIVAAYIH
HCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHC
SPRYTILAIALSALLVSGISYLALLWGWWLPVVPTLASFLLISLSLDAFYQYDRFIQTKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQQQTLRILEQAKTDLEIQVAQRTSELQQSNLELSQAKEAAEMASRAKGKFLAKMSHEL
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNAILGFSQMMAQDTTLSEANHKRNRLINQSGEHLLGLINDILSLAKLESGKQELRE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GPFQLSTLLETVEGIFRLRIEQKGLAFRVKATPDLPPYLFGDAQKLRQVLINLLSNALKF
CCHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHC
TPAGHIFLRIGSIPTPAGLTLRFEIEDTGEGIAASELHKLFVPFEQTESGEKSKAGTGLG
CCCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCC
LPISQQFAQLMGGDIKVSSQVGQGTTFTFTAQVTIAESDSDASLQNIADGVAPPPPPNDR
CCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
VEPEALPSAVISSEIIDQALGSMSANWLDELHHAALRLKGKQVIQLLSEMPPEYESASQY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHH
LIELAENYEYAHITEVTTKLTQDKP
HHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSEIWHKLRQPLAPLKLVALPSLLILGLILGGRWAGTFQSWELQVLDLFLKYQPTETQD
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
KRILLVTIDEDSIRSIGRYPIPDQYLAQSLNILQEHEPRAIGLDLFRDIPVEPGSADLAT
CEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCCHHHHH
AFQEMENLFGIDKILDENKKELDENQSERVNPPPGLPLDRVGFADAPVDLDGSQRRVMLG
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
TQTKKQVFRYSLALLLAEKFLIAQNIHLDNGINDPVAMRFKSAEIPRIRPNFGGYIRTNT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEECCCCCCCCCCCCCCEEEECC
GNADVQMLLNFRNHPKAFETVSFHKLLSGNVSPDSVRNRIVLIGITTPSFQDYSPAAIPS
CCCCHHHEEECCCCCCHHHHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCCCCCCCCCH
IISPKANWVYGIEIHAHAISQILSATLDQRPLISTWPDWIEYLCILGGGLVGIIVAAYIH
HCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHC
SPRYTILAIALSALLVSGISYLALLWGWWLPVVPTLASFLLISLSLDAFYQYDRFIQTKV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAQQQTLRILEQAKTDLEIQVAQRTSELQQSNLELSQAKEAAEMASRAKGKFLAKMSHEL
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLNAILGFSQMMAQDTTLSEANHKRNRLINQSGEHLLGLINDILSLAKLESGKQELRE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GPFQLSTLLETVEGIFRLRIEQKGLAFRVKATPDLPPYLFGDAQKLRQVLINLLSNALKF
CCHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHC
TPAGHIFLRIGSIPTPAGLTLRFEIEDTGEGIAASELHKLFVPFEQTESGEKSKAGTGLG
CCCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCCC
LPISQQFAQLMGGDIKVSSQVGQGTTFTFTAQVTIAESDSDASLQNIADGVAPPPPPNDR
CCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
VEPEALPSAVISSEIIDQALGSMSANWLDELHHAALRLKGKQVIQLLSEMPPEYESASQY
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHH
LIELAENYEYAHITEVTTKLTQDKP
HHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]