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The map label for this gene is atoS [H]

Identifier: 158338274

GI number: 158338274

Start: 5233698

End: 5234930

Strand: Direct

Name: atoS [H]

Synonym: AM1_5170

Alternate gene names: 158338274

Gene position: 5233698-5234930 (Clockwise)

Preceding gene: 158338268

Following gene: 158338276

Centisome position: 80.47

GC content: 48.42

Gene sequence:

>1233_bases
ATGTCTCAACCCCACAATCAGTCTCTTTTGACCTCTCCCCTATCGAATGAGCCTCCTCCTCGCGATCTCGCATTAGAAAT
CCTCTGGCAACACCATCAACTGATTCTCGACGCCATTGGTGAAGGGGTATATGGTCTAGATATTGAAGGCAATGTCACCT
TTGTTAATCCCGCGGCAGCCAAAATGATTGGCTGGTCCACCGCCGAGCTGATCGGTCAACCCATGCATGCGGTGCTCCAT
CACTCCCACCCCAACGGCAGCCATTACCCAAAAGAAAACTGCCCCATCTATGCCGCCTTTCGCGATGGGAAGGTCTATCG
GGTGACCGATGAGGTGTTTTGGCGTCGGGACGGTACCTGCTTTCCTGTGGAATATATCAGTACGCCTATCCATGATGAAC
AGGGCCAGATTGTAGGCGCAGTGGTCACCTTTTGCGATATCACCCAGCGTCAATGGGCTGAATCTGTTCTCAAACAAACC
AATGAAGTCTTAGAGTCAAAAGTCCGAGAACGCACCGCCGAATTAGAACAGGTCAATCAGCAACTGCAAGAGCTAAGCGC
TCTCAAATCACGATTTGTGGCGATGGTCTGCCATGAGTTCCGCAATCCTCTCAATAATATTGCCCTATCGATTTCGTCCT
TAAATCGCTATCACTCAAGGTTAACGGTTCGACAACAGTCCGAATATTTGGCAGGCATTGCCGAGAATGTCGAGCGCATG
ACGGAGATGATTGATGACATCCTCGTCATCGGCAAATTGGATGCAAAACGGATGGAGCTGAAATCGGCAGAGGTGGATCT
CGTGGCATTTTGCCAAGATTTAGTCGCCGAGGTGCAGTCAATGGCTCCTCATCATGTCGTTTTACTCATCTGTCGGCATC
GGCAGTTAATCACCCCTATAGATGTCCAACTTCTCCGGTCAATTTTGACGAATATTTTACACAATGCGATTCGCTATTCC
CCCGAGGATGGGGAGATCCAATTCAAGGTTTCACGCCGAAAGCATATCATTACGTTTCAAATTTCTGACCAAGGGATGGG
GGTTTCGCCTGAAGAGCAGTCCCTTATTTTTGATCCATTTTATCGTGGCAAAAATGTCAGTAATGTACCAGGAACGGGAT
TGGGATTGAGTATTGTCAAACAGTTTGTGGAGCTACTACAGGGCACGATTACTTTAGATAGCAGGATTGGCGTAGGAACA
ACCTTTACAGTCCGATTGCCCTGTAGTCGTTAG

Upstream 100 bases:

>100_bases
AATCTGTACGTTGTTGCCAACCCTAGAGTAGTGTCCTGGAATACAGTCTGAAGAGAGGTACCCCACGGAAGATGCAGATC
GGCACTGATTCTGCATGTAT

Downstream 100 bases:

>100_bases
ATAGACTTTGGGCCTTATTGACACACGGTCCTAACCATTAAGTCCGTTGCAGCCGATCGAGGATAGTGGCGTTGCTGTTC
TGGGTAAGTTATCCAGGATA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSQPHNQSLLTSPLSNEPPPRDLALEILWQHHQLILDAIGEGVYGLDIEGNVTFVNPAAAKMIGWSTAELIGQPMHAVLH
HSHPNGSHYPKENCPIYAAFRDGKVYRVTDEVFWRRDGTCFPVEYISTPIHDEQGQIVGAVVTFCDITQRQWAESVLKQT
NEVLESKVRERTAELEQVNQQLQELSALKSRFVAMVCHEFRNPLNNIALSISSLNRYHSRLTVRQQSEYLAGIAENVERM
TEMIDDILVIGKLDAKRMELKSAEVDLVAFCQDLVAEVQSMAPHHVVLLICRHRQLITPIDVQLLRSILTNILHNAIRYS
PEDGEIQFKVSRRKHIITFQISDQGMGVSPEEQSLIFDPFYRGKNVSNVPGTGLGLSIVKQFVELLQGTITLDSRIGVGT
TFTVRLPCSR

Sequences:

>Translated_410_residues
MSQPHNQSLLTSPLSNEPPPRDLALEILWQHHQLILDAIGEGVYGLDIEGNVTFVNPAAAKMIGWSTAELIGQPMHAVLH
HSHPNGSHYPKENCPIYAAFRDGKVYRVTDEVFWRRDGTCFPVEYISTPIHDEQGQIVGAVVTFCDITQRQWAESVLKQT
NEVLESKVRERTAELEQVNQQLQELSALKSRFVAMVCHEFRNPLNNIALSISSLNRYHSRLTVRQQSEYLAGIAENVERM
TEMIDDILVIGKLDAKRMELKSAEVDLVAFCQDLVAEVQSMAPHHVVLLICRHRQLITPIDVQLLRSILTNILHNAIRYS
PEDGEIQFKVSRRKHIITFQISDQGMGVSPEEQSLIFDPFYRGKNVSNVPGTGLGLSIVKQFVELLQGTITLDSRIGVGT
TFTVRLPCSR
>Mature_409_residues
SQPHNQSLLTSPLSNEPPPRDLALEILWQHHQLILDAIGEGVYGLDIEGNVTFVNPAAAKMIGWSTAELIGQPMHAVLHH
SHPNGSHYPKENCPIYAAFRDGKVYRVTDEVFWRRDGTCFPVEYISTPIHDEQGQIVGAVVTFCDITQRQWAESVLKQTN
EVLESKVRERTAELEQVNQQLQELSALKSRFVAMVCHEFRNPLNNIALSISSLNRYHSRLTVRQQSEYLAGIAENVERMT
EMIDDILVIGKLDAKRMELKSAEVDLVAFCQDLVAEVQSMAPHHVVLLICRHRQLITPIDVQLLRSILTNILHNAIRYSP
EDGEIQFKVSRRKHIITFQISDQGMGVSPEEQSLIFDPFYRGKNVSNVPGTGLGLSIVKQFVELLQGTITLDSRIGVGTT
FTVRLPCSR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=28.1984334203655, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=26.8, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=26.6375545851528, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=377, Percent_Identity=24.6684350132626, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=25.1063829787234, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=266, Percent_Identity=29.6992481203008, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=30.3643724696356, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=22.9965156794425, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=26.1802575107296, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=26.5917602996255, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=28.75, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=257, Percent_Identity=24.5136186770428, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=25.5060728744939, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=209, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790567, Length=385, Percent_Identity=25.974025974026, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788381, Length=121, Percent_Identity=31.404958677686, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790861, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789403, Length=225, Percent_Identity=27.1111111111111, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790551, Length=249, Percent_Identity=27.710843373494, Blast_Score=62, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322044, Length=77, Percent_Identity=38.961038961039, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46203; Mature: 46071

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPHNQSLLTSPLSNEPPPRDLALEILWQHHQLILDAIGEGVYGLDIEGNVTFVNPAAA
CCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHH
KMIGWSTAELIGQPMHAVLHHSHPNGSHYPKENCPIYAAFRDGKVYRVTDEVFWRRDGTC
HHHCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHCCCCCE
FPVEYISTPIHDEQGQIVGAVVTFCDITQRQWAESVLKQTNEVLESKVRERTAELEQVNQ
EEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQELSALKSRFVAMVCHEFRNPLNNIALSISSLNRYHSRLTVRQQSEYLAGIAENVERM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEMIDDILVIGKLDAKRMELKSAEVDLVAFCQDLVAEVQSMAPHHVVLLICRHRQLITPI
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEEHEEECCCCCCCHH
DVQLLRSILTNILHNAIRYSPEDGEIQFKVSRRKHIITFQISDQGMGVSPEEQSLIFDPF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCEEECCC
YRGKNVSNVPGTGLGLSIVKQFVELLQGTITLDSRIGVGTTFTVRLPCSR
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SQPHNQSLLTSPLSNEPPPRDLALEILWQHHQLILDAIGEGVYGLDIEGNVTFVNPAAA
CCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHH
KMIGWSTAELIGQPMHAVLHHSHPNGSHYPKENCPIYAAFRDGKVYRVTDEVFWRRDGTC
HHHCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEECCEEEEEEHHHHHCCCCCE
FPVEYISTPIHDEQGQIVGAVVTFCDITQRQWAESVLKQTNEVLESKVRERTAELEQVNQ
EEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLQELSALKSRFVAMVCHEFRNPLNNIALSISSLNRYHSRLTVRQQSEYLAGIAENVERM
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEMIDDILVIGKLDAKRMELKSAEVDLVAFCQDLVAEVQSMAPHHVVLLICRHRQLITPI
HHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEEHEEECCCCCCCHH
DVQLLRSILTNILHNAIRYSPEDGEIQFKVSRRKHIITFQISDQGMGVSPEEQSLIFDPF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCEEECCC
YRGKNVSNVPGTGLGLSIVKQFVELLQGTITLDSRIGVGTTFTVRLPCSR
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]