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The map label for this gene is ubiE [C]

Identifier: 158338190

GI number: 158338190

Start: 5136739

End: 5137707

Strand: Direct

Name: ubiE [C]

Synonym: AM1_5083

Alternate gene names: 158338190

Gene position: 5136739-5137707 (Clockwise)

Preceding gene: 158338189

Following gene: 158338191

Centisome position: 78.98

GC content: 50.67

Gene sequence:

>969_bases
ATGACGTATTTAGAATCCGCAGCAAAGTTTTACAGTCAAGTCGCTGAAACCCCAGAAGTGGGCTTATGTTGTGTCCAAAG
TACTCCTTTGCAACTGCCGGGCCTGGTGGTGCCTCCGCAAATGCAGGAAATGAACTATGGATGTGGTACAACCGTTCATC
CGACAGAATTATCGGGTAACCCTACGGTGCTGTATGTTGGCGTGGGCGGTGGCTTGGAAGCCCTGCAATTTTCCTACTTC
TCCCGTCGCCCCGGCGCTGTGGTTGCAGTAGATCCAGTGGATGAAATGCGCAAAGCGGCTGCCCGCAACCTGGAAATTGC
CGCCAAAGAAAATGAGTGGTTCGATACCAGCTTTGTCACGATTAAAGAAGGCGACGCCTTTGCCCTACCCGTCCCTGATA
ACTCCGTGGATGTTGTCGCTCAAAACTGCCTCTTCAATATTTTTGAGCCAGAAGATCTGTCTCGAGCCCTACACGAAACC
TATCGCGTCCTCAAGCCTGGTGGTCGCTTGGTCATGAGTGACCCCATTTCCACTCGCCCCATTCCAGAGCATCTCCAGCA
GGATGATCGGTTAAGAGCCATGTGTTTGTCTGGTGCCTTAACCTACGAACAATATGTTCAGCGCATTATCCATGCTGGCT
TTGGACAAGTCGAAATTCGTGCCCGTCGCCCCTATCGCCTGCTCGATCAGGAAAACTACAAGCTAGATCAGCATTTGCTA
TTAGAGAGCTTAGACTCCGTTTCCTTTAAGGTAGATATTGCCGATGATGGGGCTTGTGTGTTTACGGGCAAGATGGCGGT
TTATACCGGACCTGAAGAGTATTTTGATGACAAGGCTGGTCACATTTTGAGTTTAGGCATTCCCCTCGCCGTGTGTGACA
AGACGGCAGCCAAACTCGCCAAAGCCCATCCCCAAGCAATTATGATCACCGACTCAACTTGGTACTACGACGGTGGAGGA
TGTTGCTAA

Upstream 100 bases:

>100_bases
CTCAAATCCTCTCGATTGATGTCTTGAAGCTGCAAAAAATAAACAAACATGGCATAGTGCCCATGAATGACCATTCATTA
CAAATCCATCGTTGACCAAT

Downstream 100 bases:

>100_bases
ACGACGCCGTTTGTTGTTGTGGATCGAGCTGTTATGACTGTATCAACTAACTCAACCCTCACCCCGTTTGCCCAAAAGCT
GGTTGCCCCCCTGACGAAGC

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Domain Family; Methyltransferase-Like; UbiE/COQ5 Family Methlytransferase; UbiE/COQ5 Methyltransferase; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; Protein Containing Methyltransferase Domain; ArsR Family Transcriptional Regulator; SAM-Dependent Methyltransferases; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Transcriptional Regulator ArsR Family

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTYLESAAKFYSQVAETPEVGLCCVQSTPLQLPGLVVPPQMQEMNYGCGTTVHPTELSGNPTVLYVGVGGGLEALQFSYF
SRRPGAVVAVDPVDEMRKAAARNLEIAAKENEWFDTSFVTIKEGDAFALPVPDNSVDVVAQNCLFNIFEPEDLSRALHET
YRVLKPGGRLVMSDPISTRPIPEHLQQDDRLRAMCLSGALTYEQYVQRIIHAGFGQVEIRARRPYRLLDQENYKLDQHLL
LESLDSVSFKVDIADDGACVFTGKMAVYTGPEEYFDDKAGHILSLGIPLAVCDKTAAKLAKAHPQAIMITDSTWYYDGGG
CC

Sequences:

>Translated_322_residues
MTYLESAAKFYSQVAETPEVGLCCVQSTPLQLPGLVVPPQMQEMNYGCGTTVHPTELSGNPTVLYVGVGGGLEALQFSYF
SRRPGAVVAVDPVDEMRKAAARNLEIAAKENEWFDTSFVTIKEGDAFALPVPDNSVDVVAQNCLFNIFEPEDLSRALHET
YRVLKPGGRLVMSDPISTRPIPEHLQQDDRLRAMCLSGALTYEQYVQRIIHAGFGQVEIRARRPYRLLDQENYKLDQHLL
LESLDSVSFKVDIADDGACVFTGKMAVYTGPEEYFDDKAGHILSLGIPLAVCDKTAAKLAKAHPQAIMITDSTWYYDGGG
CC
>Mature_321_residues
TYLESAAKFYSQVAETPEVGLCCVQSTPLQLPGLVVPPQMQEMNYGCGTTVHPTELSGNPTVLYVGVGGGLEALQFSYFS
RRPGAVVAVDPVDEMRKAAARNLEIAAKENEWFDTSFVTIKEGDAFALPVPDNSVDVVAQNCLFNIFEPEDLSRALHETY
RVLKPGGRLVMSDPISTRPIPEHLQQDDRLRAMCLSGALTYEQYVQRIIHAGFGQVEIRARRPYRLLDQENYKLDQHLLL
ESLDSVSFKVDIADDGACVFTGKMAVYTGPEEYFDDKAGHILSLGIPLAVCDKTAAKLAKAHPQAIMITDSTWYYDGGGC
C

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=172, Percent_Identity=30.8139534883721, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35451; Mature: 35319

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLESAAKFYSQVAETPEVGLCCVQSTPLQLPGLVVPPQMQEMNYGCGTTVHPTELSGN
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCCHHHCCCCCCCCCCCCCCCCC
PTVLYVGVGGGLEALQFSYFSRRPGAVVAVDPVDEMRKAAARNLEIAAKENEWFDTSFVT
CEEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCEEEEECCCCCCCCEEEE
IKEGDAFALPVPDNSVDVVAQNCLFNIFEPEDLSRALHETYRVLKPGGRLVMSDPISTRP
EECCCEEEEECCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
IPEHLQQDDRLRAMCLSGALTYEQYVQRIIHAGFGQVEIRARRPYRLLDQENYKLDQHLL
CHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCEECCCCCCCCHHHHHH
LESLDSVSFKVDIADDGACVFTGKMAVYTGPEEYFDDKAGHILSLGIPLAVCDKTAAKLA
HHHHCCCEEEEEECCCCEEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHHHHHHH
KAHPQAIMITDSTWYYDGGGCC
HCCCCEEEEECCEEEECCCCCC
>Mature Secondary Structure 
TYLESAAKFYSQVAETPEVGLCCVQSTPLQLPGLVVPPQMQEMNYGCGTTVHPTELSGN
CHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCCHHHCCCCCCCCCCCCCCCCC
PTVLYVGVGGGLEALQFSYFSRRPGAVVAVDPVDEMRKAAARNLEIAAKENEWFDTSFVT
CEEEEEECCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCEEEEECCCCCCCCEEEE
IKEGDAFALPVPDNSVDVVAQNCLFNIFEPEDLSRALHETYRVLKPGGRLVMSDPISTRP
EECCCEEEEECCCCCHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
IPEHLQQDDRLRAMCLSGALTYEQYVQRIIHAGFGQVEIRARRPYRLLDQENYKLDQHLL
CHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCEECCCCCCCCHHHHHH
LESLDSVSFKVDIADDGACVFTGKMAVYTGPEEYFDDKAGHILSLGIPLAVCDKTAAKLA
HHHHCCCEEEEEECCCCEEEEECCEEEEECCHHHHCCCCCCEEEECCCHHHHHHHHHHHH
KAHPQAIMITDSTWYYDGGGCC
HCCCCEEEEECCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA