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The map label for this gene is sasA [H]

Identifier: 158338176

GI number: 158338176

Start: 5120194

End: 5121903

Strand: Direct

Name: sasA [H]

Synonym: AM1_5068

Alternate gene names: 158338176

Gene position: 5120194-5121903 (Clockwise)

Preceding gene: 158338175

Following gene: 158338179

Centisome position: 78.73

GC content: 47.49

Gene sequence:

>1710_bases
ATGCCTTGGAAGCTCGGTGTCAAATTTAGTGTGTTCTTGGTGCTGATTTTCTTAATCGGCAGTAGCTTGAAAATTTTCAC
CCTCTCACAACATTTCAATTATCAGGCCGAGAAAGCTGTGCAAGAGCGGGCAGAGATCCTGCTAACCACGATGCAGGCCG
TGCGGAACTACACTCAGGACAATATTCAACCGCGACTGGAAGACAGTCCTGAGTGGGATAGCAGTTTCGTATTAGAGAGC
GTCCCCAATTTTGCCGCCCGGACTGTTTTTGAGGATTTTAGGCAATATGCACCAGACTATCAAGCATTTTCCTATAAGGA
AGCGACCCCTAATCCCACCAACCCAGACGATCGCACTGATGAATTTGAAGCTAGCATTTTCAAGCAACTGCAAACCAGGT
CAACGGAGCAGCCCGAACGCTTATCGGGCTACCGAACGTTAGGGGAGACAAAGCTGTTTTATATCGCTCGCCCTTTAATC
ATGACAGATGCCAAATGTTTGAACTGTCATGGAAAGCCAGGCGATGCCCCCCAAAGCCAGATTGAGATGTATGGTGATCA
AAATGGGTTCGGCTGGCAGCTTAATGATGTGATTGCAGCCCAAATGATCTATGTTCCTGCCGACACAATTCTAGACCGGG
GATATCAGAATCTGTGGGCTGTCACCACCATTTTGCTGAGCCTGTTCGGAGCGCTGTTCTTGGTCATTAATCTTTTACTG
TGGCGAACTGTGATTCGCCCGCTTAAAATCCTCACACGCGTTTCGAAGCAAATTAGCAGTTGTTCACTGCAGGATGAACC
GCGCATGAAATTGAATCCATCGCAGGGCTTGGACACGCTAACCAACCGACGGGATGAACCGGGACAATTAGCGAGAGCCT
TTCAGTTTATGCTGCATGTCCTTGGTCAACGGGAGCAAGATCTTCAACTTGCGGTTCAGGAGCGAACCCAATGGCTGGAG
CAGGAAATGCATGAACGCCAAACAGCCCAGGAGTCGCTACAGCTCTATTCCCATGCCATCAACCATGACCTCCGCAACTT
GGTGATGGGTATTTCAAGTGTGGTACAAGGGATCTTATTTCAAACCTTTGGCAAAGATAAAGAGCAGCATTCAACATCAG
AGACTTCTGACGTCATCACCATTGAGCCAGCGGCACTGACCCTGATCCAGACAAGTTGCGATCGCCAACTCAATCTTATG
AATACTCTGATGACAGAAGAATCATCAGACATCTGGCGGGTTGCCCTCCAATTACAAACCATTCATCTTCAAAACCTCAC
AGCGGATCTCCAAAAGTCCTACAAAGCGAAGCTAGCCTCATCCACTATTCACAACTGCATCCCTAACGATTTGCCTCCTA
TTAAAGCCGATCCCAGTCAGCTCCAGCGGGTGTTTGAGAATTTAATTGACAATGCGCTCAAATATAACCCTAACCGCGTT
GATATTACTTTAAACGCTCGTGTTGAGGCCAGTGACTCTCCCATGATCCGTTGCACAGTGCAAGATAATGGTGTTGGTAT
CGACTCTCAAAAAATCAATTCTCTCTTTGGAGTTTACACTCGTGGCCAATCTGATACTTGCGTTACTGGGTATGGTCTTG
GCCTCTACATTTGTCGAAAAATTATTGAAGCTCACGGGGGTACAATTGGCGTTGAAACCTCTGCTGATGGCGGAGCTACA
TTTTGGTTCCTGCTGGAATTGTCCACTTGA

Upstream 100 bases:

>100_bases
CTATCTGGGCTAATTCCGCTGGTGAAGAGACCTCTTCCTTTGCCGTGGCCTAGTAGAATTATCAATTAGACAGACTCTGA
GGGGGATTGCATTACGAACA

Downstream 100 bases:

>100_bases
CTCAGTCAGTCCAGAAGGAGAACATCTGTATATTTTTGCGGGTTTTTACACTGCATTGATTTGAGGTAGCCTGAGCTAAA
GTGTCAGGACTCAGTGACCA

Product: histidine kinase domain-containing protein

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MPWKLGVKFSVFLVLIFLIGSSLKIFTLSQHFNYQAEKAVQERAEILLTTMQAVRNYTQDNIQPRLEDSPEWDSSFVLES
VPNFAARTVFEDFRQYAPDYQAFSYKEATPNPTNPDDRTDEFEASIFKQLQTRSTEQPERLSGYRTLGETKLFYIARPLI
MTDAKCLNCHGKPGDAPQSQIEMYGDQNGFGWQLNDVIAAQMIYVPADTILDRGYQNLWAVTTILLSLFGALFLVINLLL
WRTVIRPLKILTRVSKQISSCSLQDEPRMKLNPSQGLDTLTNRRDEPGQLARAFQFMLHVLGQREQDLQLAVQERTQWLE
QEMHERQTAQESLQLYSHAINHDLRNLVMGISSVVQGILFQTFGKDKEQHSTSETSDVITIEPAALTLIQTSCDRQLNLM
NTLMTEESSDIWRVALQLQTIHLQNLTADLQKSYKAKLASSTIHNCIPNDLPPIKADPSQLQRVFENLIDNALKYNPNRV
DITLNARVEASDSPMIRCTVQDNGVGIDSQKINSLFGVYTRGQSDTCVTGYGLGLYICRKIIEAHGGTIGVETSADGGAT
FWFLLELST

Sequences:

>Translated_569_residues
MPWKLGVKFSVFLVLIFLIGSSLKIFTLSQHFNYQAEKAVQERAEILLTTMQAVRNYTQDNIQPRLEDSPEWDSSFVLES
VPNFAARTVFEDFRQYAPDYQAFSYKEATPNPTNPDDRTDEFEASIFKQLQTRSTEQPERLSGYRTLGETKLFYIARPLI
MTDAKCLNCHGKPGDAPQSQIEMYGDQNGFGWQLNDVIAAQMIYVPADTILDRGYQNLWAVTTILLSLFGALFLVINLLL
WRTVIRPLKILTRVSKQISSCSLQDEPRMKLNPSQGLDTLTNRRDEPGQLARAFQFMLHVLGQREQDLQLAVQERTQWLE
QEMHERQTAQESLQLYSHAINHDLRNLVMGISSVVQGILFQTFGKDKEQHSTSETSDVITIEPAALTLIQTSCDRQLNLM
NTLMTEESSDIWRVALQLQTIHLQNLTADLQKSYKAKLASSTIHNCIPNDLPPIKADPSQLQRVFENLIDNALKYNPNRV
DITLNARVEASDSPMIRCTVQDNGVGIDSQKINSLFGVYTRGQSDTCVTGYGLGLYICRKIIEAHGGTIGVETSADGGAT
FWFLLELST
>Mature_568_residues
PWKLGVKFSVFLVLIFLIGSSLKIFTLSQHFNYQAEKAVQERAEILLTTMQAVRNYTQDNIQPRLEDSPEWDSSFVLESV
PNFAARTVFEDFRQYAPDYQAFSYKEATPNPTNPDDRTDEFEASIFKQLQTRSTEQPERLSGYRTLGETKLFYIARPLIM
TDAKCLNCHGKPGDAPQSQIEMYGDQNGFGWQLNDVIAAQMIYVPADTILDRGYQNLWAVTTILLSLFGALFLVINLLLW
RTVIRPLKILTRVSKQISSCSLQDEPRMKLNPSQGLDTLTNRRDEPGQLARAFQFMLHVLGQREQDLQLAVQERTQWLEQ
EMHERQTAQESLQLYSHAINHDLRNLVMGISSVVQGILFQTFGKDKEQHSTSETSDVITIEPAALTLIQTSCDRQLNLMN
TLMTEESSDIWRVALQLQTIHLQNLTADLQKSYKAKLASSTIHNCIPNDLPPIKADPSQLQRVFENLIDNALKYNPNRVD
ITLNARVEASDSPMIRCTVQDNGVGIDSQKINSLFGVYTRGQSDTCVTGYGLGLYICRKIIEAHGGTIGVETSADGGATF
WFLLELST

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: COG2770

COG function: function code T; FOG: HAMP domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=122, Percent_Identity=37.7049180327869, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789149, Length=370, Percent_Identity=24.0540540540541, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=254, Percent_Identity=23.6220472440945, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=24.6963562753036, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081816, Length=351, Percent_Identity=24.2165242165242, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 64380; Mature: 64249

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWKLGVKFSVFLVLIFLIGSSLKIFTLSQHFNYQAEKAVQERAEILLTTMQAVRNYTQD
CCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIQPRLEDSPEWDSSFVLESVPNFAARTVFEDFRQYAPDYQAFSYKEATPNPTNPDDRTD
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EFEASIFKQLQTRSTEQPERLSGYRTLGETKLFYIARPLIMTDAKCLNCHGKPGDAPQSQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEHHEECHHHHCCHHHHCCCCCCCCCCHHH
IEMYGDQNGFGWQLNDVIAAQMIYVPADTILDRGYQNLWAVTTILLSLFGALFLVINLLL
HHHCCCCCCCCEEHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WRTVIRPLKILTRVSKQISSCSLQDEPRMKLNPSQGLDTLTNRRDEPGQLARAFQFMLHV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
LGQREQDLQLAVQERTQWLEQEMHERQTAQESLQLYSHAINHDLRNLVMGISSVVQGILF
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTFGKDKEQHSTSETSDVITIEPAALTLIQTSCDRQLNLMNTLMTEESSDIWRVALQLQT
HHHCCCHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IHLQNLTADLQKSYKAKLASSTIHNCIPNDLPPIKADPSQLQRVFENLIDNALKYNPNRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
DITLNARVEASDSPMIRCTVQDNGVGIDSQKINSLFGVYTRGQSDTCVTGYGLGLYICRK
EEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHH
IIEAHGGTIGVETSADGGATFWFLLELST
HHHHCCCEEEEECCCCCCCEEEEEEEECC
>Mature Secondary Structure 
PWKLGVKFSVFLVLIFLIGSSLKIFTLSQHFNYQAEKAVQERAEILLTTMQAVRNYTQD
CCCCCCHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NIQPRLEDSPEWDSSFVLESVPNFAARTVFEDFRQYAPDYQAFSYKEATPNPTNPDDRTD
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EFEASIFKQLQTRSTEQPERLSGYRTLGETKLFYIARPLIMTDAKCLNCHGKPGDAPQSQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEHHEECHHHHCCHHHHCCCCCCCCCCHHH
IEMYGDQNGFGWQLNDVIAAQMIYVPADTILDRGYQNLWAVTTILLSLFGALFLVINLLL
HHHCCCCCCCCEEHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WRTVIRPLKILTRVSKQISSCSLQDEPRMKLNPSQGLDTLTNRRDEPGQLARAFQFMLHV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
LGQREQDLQLAVQERTQWLEQEMHERQTAQESLQLYSHAINHDLRNLVMGISSVVQGILF
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTFGKDKEQHSTSETSDVITIEPAALTLIQTSCDRQLNLMNTLMTEESSDIWRVALQLQT
HHHCCCHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IHLQNLTADLQKSYKAKLASSTIHNCIPNDLPPIKADPSQLQRVFENLIDNALKYNPNRV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
DITLNARVEASDSPMIRCTVQDNGVGIDSQKINSLFGVYTRGQSDTCVTGYGLGLYICRK
EEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHH
IIEAHGGTIGVETSADGGATFWFLLELST
HHHHCCCEEEEECCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA