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The map label for this gene is degU [H]

Identifier: 158338160

GI number: 158338160

Start: 5098782

End: 5099498

Strand: Reverse

Name: degU [H]

Synonym: AM1_5052

Alternate gene names: 158338160

Gene position: 5099498-5098782 (Counterclockwise)

Preceding gene: 158338161

Following gene: 158338159

Centisome position: 78.41

GC content: 50.49

Gene sequence:

>717_bases
ATGACTAAAATTCAGGTTGTTATTATCGAAGACCATGATCTCAGCCGTGTGGGCCTAACCGCCGCGCTCCAGCACAGTGG
GACCGTGGATGTCCTCGGGTCGGCGGCCAATGGTCGCCAGGGTTTGGAGATGATTCAGCAATACAAACCCGATGTTGCCA
TTTTGGATATTGGCTTGCCCGACATCGACGGCATTGAAGTCACCCTACAGCTCAAACAATTCCAGCAAGCGGATGACAGC
TTGCAAACTAAGGTGCTGATGCTGACAGCCAATACCAGTGAAGATGCCGTACTGGCGGCCTTTGCTGCTGGCGCAGATTC
CTACAGCCTCAAGGAAGTTAGTGTCGAGGATTTACTCAGCGCCATTCAGCTGACCCATGAAGGCAATGCTTGGATTGATC
CCAACATTGCTCGGATTGTCTTGCAACAGGCTAAAGCGTCAAAAAAGACTCCTCAAGATGCTGAAACCGACACCACAGTA
ATTAAAGCCACCGATCCGGAATACCAAGCCATCCTAGAAACAGAACCGTTAACGGATCGCGAATTAGAAGTTTTAGAACT
GATTGTGGCAGGATGCAGTAACGCCGTGATTGCAGACAAGCTCTATATTTCCGTCGGCACCGTCAAAACTCACGTGCGCA
GCATTTTGAATAAACTCTGCGCCGATGACCGAACCCAAGCTGCCGTCAGAGCCCTTCGGTCAGGCTTAGTCACTTAA

Upstream 100 bases:

>100_bases
CATTGAAGTCAAACGAACATTCTCCTCTGAACGACCTATCTTTAACGGCACCCTAGTCCGTTTCCTGCTCCTCTTACTCA
CCCGTTAACAAGGCGAATCC

Downstream 100 bases:

>100_bases
TAAGTTTCCAGGGAGACTGAATCTAACGTTGCAACACTATGGGACAAGCCGAGCAAACGTCTAAAGCCAAAAAATCTGCA
AAGGGAAAATCCATCCTGTA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTKIQVVIIEDHDLSRVGLTAALQHSGTVDVLGSAANGRQGLEMIQQYKPDVAILDIGLPDIDGIEVTLQLKQFQQADDS
LQTKVLMLTANTSEDAVLAAFAAGADSYSLKEVSVEDLLSAIQLTHEGNAWIDPNIARIVLQQAKASKKTPQDAETDTTV
IKATDPEYQAILETEPLTDRELEVLELIVAGCSNAVIADKLYISVGTVKTHVRSILNKLCADDRTQAAVRALRSGLVT

Sequences:

>Translated_238_residues
MTKIQVVIIEDHDLSRVGLTAALQHSGTVDVLGSAANGRQGLEMIQQYKPDVAILDIGLPDIDGIEVTLQLKQFQQADDS
LQTKVLMLTANTSEDAVLAAFAAGADSYSLKEVSVEDLLSAIQLTHEGNAWIDPNIARIVLQQAKASKKTPQDAETDTTV
IKATDPEYQAILETEPLTDRELEVLELIVAGCSNAVIADKLYISVGTVKTHVRSILNKLCADDRTQAAVRALRSGLVT
>Mature_237_residues
TKIQVVIIEDHDLSRVGLTAALQHSGTVDVLGSAANGRQGLEMIQQYKPDVAILDIGLPDIDGIEVTLQLKQFQQADDSL
QTKVLMLTANTSEDAVLAAFAAGADSYSLKEVSVEDLLSAIQLTHEGNAWIDPNIARIVLQQAKASKKTPQDAETDTTVI
KATDPEYQAILETEPLTDRELEVLELIVAGCSNAVIADKLYISVGTVKTHVRSILNKLCADDRTQAAVRALRSGLVT

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787473, Length=224, Percent_Identity=29.4642857142857, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788521, Length=228, Percent_Identity=28.5087719298246, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788222, Length=233, Percent_Identity=25.7510729613734, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786747, Length=219, Percent_Identity=25.5707762557078, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787375, Length=172, Percent_Identity=29.0697674418605, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25616; Mature: 25485

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIQVVIIEDHDLSRVGLTAALQHSGTVDVLGSAANGRQGLEMIQQYKPDVAILDIGLP
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCC
DIDGIEVTLQLKQFQQADDSLQTKVLMLTANTSEDAVLAAFAAGADSYSLKEVSVEDLLS
CCCCEEEEEEEHHHHCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCHHCCHHHHHH
AIQLTHEGNAWIDPNIARIVLQQAKASKKTPQDAETDTTVIKATDPEYQAILETEPLTDR
HHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHEEEECCCCCCC
ELEVLELIVAGCSNAVIADKLYISVGTVKTHVRSILNKLCADDRTQAAVRALRSGLVT
HHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKIQVVIIEDHDLSRVGLTAALQHSGTVDVLGSAANGRQGLEMIQQYKPDVAILDIGLP
CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCC
DIDGIEVTLQLKQFQQADDSLQTKVLMLTANTSEDAVLAAFAAGADSYSLKEVSVEDLLS
CCCCEEEEEEEHHHHCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCHHCCHHHHHH
AIQLTHEGNAWIDPNIARIVLQQAKASKKTPQDAETDTTVIKATDPEYQAILETEPLTDR
HHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHEEEECCCCCCC
ELEVLELIVAGCSNAVIADKLYISVGTVKTHVRSILNKLCADDRTQAAVRALRSGLVT
HHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]