Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 158338058

GI number: 158338058

Start: 4982828

End: 4984585

Strand: Reverse

Name: yciR [C]

Synonym: AM1_4945

Alternate gene names: 158338058

Gene position: 4984585-4982828 (Counterclockwise)

Preceding gene: 158338059

Following gene: 158338056

Centisome position: 76.64

GC content: 45.56

Gene sequence:

>1758_bases
ATGTCAAAGGCTGCTTTAGCAAAGGTATTATCGGCTCTAGAGATTTTAGTGCTGGAATACCAAGATGACCAATCTTTTCA
GGTGATTGGTCATCTGCCATCCTGGTATCGGTCTTTAATGGGAGCGAATCAAGAGCCATCTGCAGTGATTTATCTAGCGG
ATGCATTTCCTTTTCTGACTTATTTTCTGGACGATGCGTTGCAGTTTTGGCAAACTGAGCAAGAACAAGTCCTAAAATCT
GGCTTGTGGGTTGAGGTGGATCAGTCGGGAACTGAAATTCCCCTGGAAGCATCAGCCCTGGGCTTAGACGACCAAAGAAT
CATACTGATTGCTTTATCCCAGACGACCTATACAGAAAAGTCAGTTTTAATTCAGCAAGGTCGAGAAAATGCCCTGGCCC
AAAGTGCTGAGCGTAAACGAGCAGCCGAGCAGCTGCGCCATAGTATTTTTTATGATTGGCTAACGGAATTACCCAACCAG
TCCTTTATTCGATTGCGGTTGGTGGATGCTCTGTCCCAGACCAAAACTGGGCCAGATGGCTCTTTTGCCCTTCTCTACAT
TGATATTAAGCACTTTAAGGCCATTAACACCCGCTTAGGATTATGGGCCGGTGACCAACTATTGATGATGGTTGCCCAGC
GATTGTCTGAGCTTTTAAGGCCCGATGATATCGCAGCTCGTTTCGGTGGAGATGATTTTGTTGTTCTCCTTCGGCCCGTT
GATGGTGAACAAGAGACTCGAAAAATTACCGAAAAAATTCAGCGCCATCTCTTGGTCCCTTACGCGATCCACTCCCAAGA
CATTCATATACAGTTTGATATGGGGATTGCCATGGGCTCGTCTCTGTATCAACAACCAGAAGATTTAATCCGTGATGCTT
GTACGGCACTGGAATATGCCAAAAGTCATGGGGCAGAGAACTATGCGATTTTTCACCAGACGATGCATTTGCAATCCCTG
ACCCGCATGCAGTTGGAACATGATTTGTCCCGGGCGGTTTGGCAAAATGAGTTACGGGTTTGCTATCAACCCATCATCTC
CTTAGCAGATGGTTCTCTGCAGGCCTTTGAAGCGTTAGTGCGATGGCAACATCCCACATTAGGGTTGTTGTCACCGGATC
AGTTTATTGCGATCGCAGAAGATAGCGGCCTGATTATTCCCATTGGCGCCTGGATCTTAAGAGAAGCCTGTGAACAGATC
CATAAATGGCGTAATCAAACCCATTTGCCGTTGAGTATGCATGTCAATTTATCGGCTCGACAGCTCGATCAGCTAGATTT
GCTGGATTCAATCCGAGGCATCTTAGCCGAAACACAGCTTGACCCTAGGGGATTAAAGCTAGAAATTACCGAGACGATGG
TGTTCAACAATTTGGAATATGCGGCGGCAATGCTGCGGCAAATAAAAGGCTTGGGGATTCAACTCAGTATGGATGACTTT
GGAACGGGGTATGCCTCTTTAAGTTATCTCCATCAACTCCCCGTCGATAATCTTAAGATCGATCGATCCTTTGTGGAAAC
CATTGATACTTCTGGAACAGAATCAGAGATTATTCAAGCCGTTATTCAGCTTGCCCATAGTTTGAATATTGATGTGGTAG
CTGAAGGGGTAGAGACTGTAGAGCAGGCCAACCGGCTGAAAAACTTGGGATGTGAATATGCGCAAGGCTACTTGTTTGCT
AAACCTATGGAACCAGGACAAATAGAAAAAGTTCTCCACAAAAATTTTGCTTCTCTATTCGACGCTGTTCAAGTTTAA

Upstream 100 bases:

>100_bases
GAGGTTGCCGTCCAGGTCATGGCAGAAGTTTGGGATGCCTGTAATCGTAATAGTGCTTCCAGAAAAAATGGTGCCAGAAG
ACATGTGGAATAGTTGAACG

Downstream 100 bases:

>100_bases
TTGGGGACTCTTAAAAGTTTTTAGCTCAAAGTCCAACCGAAAGATCTGCTAGTTTTGATCGATTGCTGTTCTAGCTGATA
TTTATCGACTAGTTTCACCA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MSKAALAKVLSALEILVLEYQDDQSFQVIGHLPSWYRSLMGANQEPSAVIYLADAFPFLTYFLDDALQFWQTEQEQVLKS
GLWVEVDQSGTEIPLEASALGLDDQRIILIALSQTTYTEKSVLIQQGRENALAQSAERKRAAEQLRHSIFYDWLTELPNQ
SFIRLRLVDALSQTKTGPDGSFALLYIDIKHFKAINTRLGLWAGDQLLMMVAQRLSELLRPDDIAARFGGDDFVVLLRPV
DGEQETRKITEKIQRHLLVPYAIHSQDIHIQFDMGIAMGSSLYQQPEDLIRDACTALEYAKSHGAENYAIFHQTMHLQSL
TRMQLEHDLSRAVWQNELRVCYQPIISLADGSLQAFEALVRWQHPTLGLLSPDQFIAIAEDSGLIIPIGAWILREACEQI
HKWRNQTHLPLSMHVNLSARQLDQLDLLDSIRGILAETQLDPRGLKLEITETMVFNNLEYAAAMLRQIKGLGIQLSMDDF
GTGYASLSYLHQLPVDNLKIDRSFVETIDTSGTESEIIQAVIQLAHSLNIDVVAEGVETVEQANRLKNLGCEYAQGYLFA
KPMEPGQIEKVLHKNFASLFDAVQV

Sequences:

>Translated_585_residues
MSKAALAKVLSALEILVLEYQDDQSFQVIGHLPSWYRSLMGANQEPSAVIYLADAFPFLTYFLDDALQFWQTEQEQVLKS
GLWVEVDQSGTEIPLEASALGLDDQRIILIALSQTTYTEKSVLIQQGRENALAQSAERKRAAEQLRHSIFYDWLTELPNQ
SFIRLRLVDALSQTKTGPDGSFALLYIDIKHFKAINTRLGLWAGDQLLMMVAQRLSELLRPDDIAARFGGDDFVVLLRPV
DGEQETRKITEKIQRHLLVPYAIHSQDIHIQFDMGIAMGSSLYQQPEDLIRDACTALEYAKSHGAENYAIFHQTMHLQSL
TRMQLEHDLSRAVWQNELRVCYQPIISLADGSLQAFEALVRWQHPTLGLLSPDQFIAIAEDSGLIIPIGAWILREACEQI
HKWRNQTHLPLSMHVNLSARQLDQLDLLDSIRGILAETQLDPRGLKLEITETMVFNNLEYAAAMLRQIKGLGIQLSMDDF
GTGYASLSYLHQLPVDNLKIDRSFVETIDTSGTESEIIQAVIQLAHSLNIDVVAEGVETVEQANRLKNLGCEYAQGYLFA
KPMEPGQIEKVLHKNFASLFDAVQV
>Mature_584_residues
SKAALAKVLSALEILVLEYQDDQSFQVIGHLPSWYRSLMGANQEPSAVIYLADAFPFLTYFLDDALQFWQTEQEQVLKSG
LWVEVDQSGTEIPLEASALGLDDQRIILIALSQTTYTEKSVLIQQGRENALAQSAERKRAAEQLRHSIFYDWLTELPNQS
FIRLRLVDALSQTKTGPDGSFALLYIDIKHFKAINTRLGLWAGDQLLMMVAQRLSELLRPDDIAARFGGDDFVVLLRPVD
GEQETRKITEKIQRHLLVPYAIHSQDIHIQFDMGIAMGSSLYQQPEDLIRDACTALEYAKSHGAENYAIFHQTMHLQSLT
RMQLEHDLSRAVWQNELRVCYQPIISLADGSLQAFEALVRWQHPTLGLLSPDQFIAIAEDSGLIIPIGAWILREACEQIH
KWRNQTHLPLSMHVNLSARQLDQLDLLDSIRGILAETQLDPRGLKLEITETMVFNNLEYAAAMLRQIKGLGIQLSMDDFG
TGYASLSYLHQLPVDNLKIDRSFVETIDTSGTESEIIQAVIQLAHSLNIDVVAEGVETVEQANRLKNLGCEYAQGYLFAK
PMEPGQIEKVLHKNFASLFDAVQV

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=33.6405529953917, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081921, Length=445, Percent_Identity=31.685393258427, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI226510982, Length=426, Percent_Identity=30.5164319248826, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=36.6935483870968, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081845, Length=249, Percent_Identity=34.9397590361446, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=35.4166666666667, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=34.4398340248963, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=33.6099585062241, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=33.4645669291339, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788502, Length=262, Percent_Identity=31.6793893129771, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1788849, Length=474, Percent_Identity=27.0042194092827, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87082096, Length=200, Percent_Identity=33.5, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787410, Length=136, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082007, Length=134, Percent_Identity=33.5820895522388, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=31.4814814814815, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788381, Length=179, Percent_Identity=29.0502793296089, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=27.906976744186, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 65969; Mature: 65838

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAALAKVLSALEILVLEYQDDQSFQVIGHLPSWYRSLMGANQEPSAVIYLADAFPFLT
CCHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEEHHHHHHH
YFLDDALQFWQTEQEQVLKSGLWVEVDQSGTEIPLEASALGLDDQRIILIALSQTTYTEK
HHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCHHH
SVLIQQGRENALAQSAERKRAAEQLRHSIFYDWLTELPNQSFIRLRLVDALSQTKTGPDG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCC
SFALLYIDIKHFKAINTRLGLWAGDQLLMMVAQRLSELLRPDDIAARFGGDDFVVLLRPV
CEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECC
DGEQETRKITEKIQRHLLVPYAIHSQDIHIQFDMGIAMGSSLYQQPEDLIRDACTALEYA
CCCHHHHHHHHHHHHHEECCEEECCCEEEEEEECCHHHCCHHHCCHHHHHHHHHHHHHHH
KSHGAENYAIFHQTMHLQSLTRMQLEHDLSRAVWQNELRVCYQPIISLADGSLQAFEALV
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RWQHPTLGLLSPDQFIAIAEDSGLIIPIGAWILREACEQIHKWRNQTHLPLSMHVNLSAR
HCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
QLDQLDLLDSIRGILAETQLDPRGLKLEITETMVFNNLEYAAAMLRQIKGLGIQLSMDDF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCEEEECCCC
GTGYASLSYLHQLPVDNLKIDRSFVETIDTSGTESEIIQAVIQLAHSLNIDVVAEGVETV
CCCHHHHHHHHHCCCCCEEECHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EQANRLKNLGCEYAQGYLFAKPMEPGQIEKVLHKNFASLFDAVQV
HHHHHHHHCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKAALAKVLSALEILVLEYQDDQSFQVIGHLPSWYRSLMGANQEPSAVIYLADAFPFLT
CHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEEHHHHHHH
YFLDDALQFWQTEQEQVLKSGLWVEVDQSGTEIPLEASALGLDDQRIILIALSQTTYTEK
HHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCCHHHCCCCCCEEEEEEECCCCCHHH
SVLIQQGRENALAQSAERKRAAEQLRHSIFYDWLTELPNQSFIRLRLVDALSQTKTGPDG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCC
SFALLYIDIKHFKAINTRLGLWAGDQLLMMVAQRLSELLRPDDIAARFGGDDFVVLLRPV
CEEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECC
DGEQETRKITEKIQRHLLVPYAIHSQDIHIQFDMGIAMGSSLYQQPEDLIRDACTALEYA
CCCHHHHHHHHHHHHHEECCEEECCCEEEEEEECCHHHCCHHHCCHHHHHHHHHHHHHHH
KSHGAENYAIFHQTMHLQSLTRMQLEHDLSRAVWQNELRVCYQPIISLADGSLQAFEALV
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RWQHPTLGLLSPDQFIAIAEDSGLIIPIGAWILREACEQIHKWRNQTHLPLSMHVNLSAR
HCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHH
QLDQLDLLDSIRGILAETQLDPRGLKLEITETMVFNNLEYAAAMLRQIKGLGIQLSMDDF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCEEEECCCC
GTGYASLSYLHQLPVDNLKIDRSFVETIDTSGTESEIIQAVIQLAHSLNIDVVAEGVETV
CCCHHHHHHHHHCCCCCEEECHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
EQANRLKNLGCEYAQGYLFAKPMEPGQIEKVLHKNFASLFDAVQV
HHHHHHHHCCCHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]