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The map label for this gene is apaH [H]

Identifier: 158338027

GI number: 158338027

Start: 4960611

End: 4961366

Strand: Reverse

Name: apaH [H]

Synonym: AM1_4914

Alternate gene names: 158338027

Gene position: 4961366-4960611 (Counterclockwise)

Preceding gene: 158338032

Following gene: 158338023

Centisome position: 76.29

GC content: 47.62

Gene sequence:

>756_bases
ATGAGTGCACAACAACTGCGTCGATTTGTCATCGGGGATATTCATGGTCACTATCAAGGGTTACTTGATCTAGTATCCCT
ACTTGAGATTGGCGAATCTGATCAAATCTACTTTTTAGGTGACCTTATTGATCGAGGCCCTGATAGCTCTAAAGTCGTAG
ATTTTGTTCGAGAACAGTCTTACACCTGTTTGTTAGGAAATCATGAGCAGCTGATGGTAGCGGCTTTGGCGAATCTTTCC
CCAAATTCATCCGTATTGCAAATGTGGTTGCAGGCAGGGGGGCGAGAAACCCTGCAAAGCTACAGCTCCAAACAGCATCT
TTGGGAGCATTTGAGTTGGATTAAAACCCTGCCAAATCATCTCGATTTAGGAGATTATTGGCTCGTCCATGCTGGGATTA
ACCCAGATCTGCCGTTAGAACGTCAGACGGCCCAGGAATTTTGTTGGATTCGACGGGAATTCCACAATATGCCACAGCCC
TATTTCCCAGACAGAATGATTATTACCGGCCATACCATGACCTTCACATTCTCAGGGGTTGAACCTGGCCAAATCGTTCA
AGGTGCAGGCTGGCTCGGGATTGATACTGGCGCTTACCATCCAGGCAGTGGTTGGTTAACAGCCCTGGAACTGTCCTCGT
CCACCGTGTATCAGATCAATGTCCATAGCAATGTCTCTCGGGTCAAGCCCCTGGCAGATGTGTTGGTGTCTTTGCCCCAT
GGCCAGGACACACTATCAATGCCAATGTCTAGTTAA

Upstream 100 bases:

>100_bases
TAGTGGTAACTGTAGTTTTAGCGATTTTGTCTTTAGATTTTAGTCTTTTCAACGTATAGCATGGCTATTGTTACCCCTGG
ACCTTGCATAGCATTTGTGG

Downstream 100 bases:

>100_bases
CCCATAAAAAAATCAGGCGTTGAGAGCAGCCCCAACACCTGAATATAGAAATCTATAGATAGGAATGTGTTACACGCCAA
CCGTTTCTGACGTCTTGGTT

Product: serine/threonine protein phosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSAQQLRRFVIGDIHGHYQGLLDLVSLLEIGESDQIYFLGDLIDRGPDSSKVVDFVREQSYTCLLGNHEQLMVAALANLS
PNSSVLQMWLQAGGRETLQSYSSKQHLWEHLSWIKTLPNHLDLGDYWLVHAGINPDLPLERQTAQEFCWIRREFHNMPQP
YFPDRMIITGHTMTFTFSGVEPGQIVQGAGWLGIDTGAYHPGSGWLTALELSSSTVYQINVHSNVSRVKPLADVLVSLPH
GQDTLSMPMSS

Sequences:

>Translated_251_residues
MSAQQLRRFVIGDIHGHYQGLLDLVSLLEIGESDQIYFLGDLIDRGPDSSKVVDFVREQSYTCLLGNHEQLMVAALANLS
PNSSVLQMWLQAGGRETLQSYSSKQHLWEHLSWIKTLPNHLDLGDYWLVHAGINPDLPLERQTAQEFCWIRREFHNMPQP
YFPDRMIITGHTMTFTFSGVEPGQIVQGAGWLGIDTGAYHPGSGWLTALELSSSTVYQINVHSNVSRVKPLADVLVSLPH
GQDTLSMPMSS
>Mature_250_residues
SAQQLRRFVIGDIHGHYQGLLDLVSLLEIGESDQIYFLGDLIDRGPDSSKVVDFVREQSYTCLLGNHEQLMVAALANLSP
NSSVLQMWLQAGGRETLQSYSSKQHLWEHLSWIKTLPNHLDLGDYWLVHAGINPDLPLERQTAQEFCWIRREFHNMPQPY
FPDRMIITGHTMTFTFSGVEPGQIVQGAGWLGIDTGAYHPGSGWLTALELSSSTVYQINVHSNVSRVKPLADVLVSLPHG
QDTLSMPMSS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 28127; Mature: 27996

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQQLRRFVIGDIHGHYQGLLDLVSLLEIGESDQIYFLGDLIDRGPDSSKVVDFVREQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCC
YTCLLGNHEQLMVAALANLSPNSSVLQMWLQAGGRETLQSYSSKQHLWEHLSWIKTLPNH
CEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LDLGDYWLVHAGINPDLPLERQTAQEFCWIRREFHNMPQPYFPDRMIITGHTMTFTFSGV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCC
EPGQIVQGAGWLGIDTGAYHPGSGWLTALELSSSTVYQINVHSNVSRVKPLADVLVSLPH
CCCCEEECCCEEEECCCCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCC
GQDTLSMPMSS
CCCCCCCCCCC
>Mature Secondary Structure 
SAQQLRRFVIGDIHGHYQGLLDLVSLLEIGESDQIYFLGDLIDRGPDSSKVVDFVREQS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHHHHHHHHHCC
YTCLLGNHEQLMVAALANLSPNSSVLQMWLQAGGRETLQSYSSKQHLWEHLSWIKTLPNH
CEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LDLGDYWLVHAGINPDLPLERQTAQEFCWIRREFHNMPQPYFPDRMIITGHTMTFTFSGV
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCC
EPGQIVQGAGWLGIDTGAYHPGSGWLTALELSSSTVYQINVHSNVSRVKPLADVLVSLPH
CCCCEEECCCEEEECCCCCCCCCCCEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCC
GQDTLSMPMSS
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA