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The map label for this gene is trxB [H]

Identifier: 158338023

GI number: 158338023

Start: 4957431

End: 4958858

Strand: Reverse

Name: trxB [H]

Synonym: AM1_4910

Alternate gene names: 158338023

Gene position: 4958858-4957431 (Counterclockwise)

Preceding gene: 158338027

Following gene: 158338022

Centisome position: 76.25

GC content: 51.12

Gene sequence:

>1428_bases
TTGCAAAACGGCTCAAAAAGCCAATGCTCCATCCGCAGCCGTTACCTTACTGTTCTTATGAGTGAAGCGATTGAAAACTT
GGTGGTCATTGGATCAGGGCCCGCTGGCTATACGGCGGCTATTTACGCTGCCCGAGCAAACTTAAAGCCCTTTATGTTTG
CCGGATATCAGGCTGGGGGACTGCCGGGTGGGCAACTAATGACGACCACAGAAGTAGAGAATTTCCCAGGTTTCCCGGAT
GGGATTACTGGACCGCAGCTGATGGATCGGATGAAGCTACAGGCCCTACGTTGGGGAAGTGAGATTGTCACGGAAGACGT
AATATCCGTTGACTTCCAACAGTTCCCGTTTGTGATCCAGTCTGAAGAAAGAACGGTGAAGGCCCATAGCGTGGTTATTG
CGACCGGGGCAACGGCCAAACGATTGGGCTTGCCGTCAGAAAAAGAGTTTTGGAGTCGAGGAATTTCGGCCTGCGCCATT
TGTGATGGGGCAACACCTATTTTCAAGAATGAGGAACTCGCCGTGGTGGGGGGAGGAGATTCTGCGGCTGAAGAAGCGGT
TTATCTGACGAAATATGGCTCTCATGTGCATCTACTGGTTCGCTCAGAGCAGATGCGGGCGAGCAAAGCCATGCAGGATC
GGGTGATGCGAAATCCTAAAGTTACTGTCCATTGGCAAACCGAGGTGGTGGATGTCTTTGGCGATACACAGCTCCAAGGA
CTCAAAATCAAAAACCGTCAGACTGCAGAGATCCAAGAACTGCAGGTGCGGGGGCTATTTTATGCCATCGGCCATCAGCC
CAATACCCAACTCTTTACCCAACAGCTGGATTTGGATAAGACGGGCTACATCCTGACTCAGCCCGATTCGGTCAGCACTA
ATATTTTTGGCGTGTTTGCGGCTGGAGATGTTCAAGAGCATGAGTTTAGACAAGCGATTACTGCTGCTGGAACGGGGTGC
ATGGCGGCTTTATTAGCAGAGCGCTGGTTGTCATCTCAGGATTTGATTAACGAGTTTCACCAATCGGAAGCCTCTGAACA
AACGGAAGATGGGACCCATCCGCCAGAGTACAAGCTGTCGGCAGCGTTTGATCCCAACACCACTCGCCATCAAGGGGCAT
TTGCCTTGCGGAAGTTGTTTCATGAGAGCGATCGCATCATCGTAGTCAAATATGCATCTCCCACCTGTGGCCCCTGCCAT
ATCCTCCAGCCGATCTTGAGTCGCGTCATTGATGAATTTGAAGGACAGGTGCACTACGTGGAGATTGACATTGCCGAAGA
TCCAGATATTGCCGAATCTGCCTCCATAACAGGGACCCCAACAGTGCAGGTATTCCAGGATAAATCCTTATTACGGGAGT
TCAAAGGGATTAAAGCAAAGCAAGCGTACCGGGACGCGATCAACGAACTGCTGGCGGCAACTTCATAG

Upstream 100 bases:

>100_bases
GACTCAGACATGGGCAAACTTTTTAAGCGGATGATGGCAGCAGAATAATTTCACTATAGTAAAGCGTTGGAGATTTTTTG
AGTCAAAGGCTTTAGAACAA

Downstream 100 bases:

>100_bases
AGATTTGAATTCCTGATGGGTTATAAACCCTCTTGTAAACGAAGAGAGTTACAATGTGATAAGCATATGTAAAATTTTGT
AATCTTTATTTCATAACCGT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MQNGSKSQCSIRSRYLTVLMSEAIENLVVIGSGPAGYTAAIYAARANLKPFMFAGYQAGGLPGGQLMTTTEVENFPGFPD
GITGPQLMDRMKLQALRWGSEIVTEDVISVDFQQFPFVIQSEERTVKAHSVVIATGATAKRLGLPSEKEFWSRGISACAI
CDGATPIFKNEELAVVGGGDSAAEEAVYLTKYGSHVHLLVRSEQMRASKAMQDRVMRNPKVTVHWQTEVVDVFGDTQLQG
LKIKNRQTAEIQELQVRGLFYAIGHQPNTQLFTQQLDLDKTGYILTQPDSVSTNIFGVFAAGDVQEHEFRQAITAAGTGC
MAALLAERWLSSQDLINEFHQSEASEQTEDGTHPPEYKLSAAFDPNTTRHQGAFALRKLFHESDRIIVVKYASPTCGPCH
ILQPILSRVIDEFEGQVHYVEIDIAEDPDIAESASITGTPTVQVFQDKSLLREFKGIKAKQAYRDAINELLAATS

Sequences:

>Translated_475_residues
MQNGSKSQCSIRSRYLTVLMSEAIENLVVIGSGPAGYTAAIYAARANLKPFMFAGYQAGGLPGGQLMTTTEVENFPGFPD
GITGPQLMDRMKLQALRWGSEIVTEDVISVDFQQFPFVIQSEERTVKAHSVVIATGATAKRLGLPSEKEFWSRGISACAI
CDGATPIFKNEELAVVGGGDSAAEEAVYLTKYGSHVHLLVRSEQMRASKAMQDRVMRNPKVTVHWQTEVVDVFGDTQLQG
LKIKNRQTAEIQELQVRGLFYAIGHQPNTQLFTQQLDLDKTGYILTQPDSVSTNIFGVFAAGDVQEHEFRQAITAAGTGC
MAALLAERWLSSQDLINEFHQSEASEQTEDGTHPPEYKLSAAFDPNTTRHQGAFALRKLFHESDRIIVVKYASPTCGPCH
ILQPILSRVIDEFEGQVHYVEIDIAEDPDIAESASITGTPTVQVFQDKSLLREFKGIKAKQAYRDAINELLAATS
>Mature_475_residues
MQNGSKSQCSIRSRYLTVLMSEAIENLVVIGSGPAGYTAAIYAARANLKPFMFAGYQAGGLPGGQLMTTTEVENFPGFPD
GITGPQLMDRMKLQALRWGSEIVTEDVISVDFQQFPFVIQSEERTVKAHSVVIATGATAKRLGLPSEKEFWSRGISACAI
CDGATPIFKNEELAVVGGGDSAAEEAVYLTKYGSHVHLLVRSEQMRASKAMQDRVMRNPKVTVHWQTEVVDVFGDTQLQG
LKIKNRQTAEIQELQVRGLFYAIGHQPNTQLFTQQLDLDKTGYILTQPDSVSTNIFGVFAAGDVQEHEFRQAITAAGTGC
MAALLAERWLSSQDLINEFHQSEASEQTEDGTHPPEYKLSAAFDPNTTRHQGAFALRKLFHESDRIIVVKYASPTCGPCH
ILQPILSRVIDEFEGQVHYVEIDIAEDPDIAESASITGTPTVQVFQDKSLLREFKGIKAKQAYRDAINELLAATS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=47.9233226837061, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI87081763, Length=299, Percent_Identity=28.7625418060201, Blast_Score=141, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=53.3546325878594, Blast_Score=347, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=50.9554140127389, Blast_Score=333, Evalue=4e-92,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 52182; Mature: 52182

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNGSKSQCSIRSRYLTVLMSEAIENLVVIGSGPAGYTAAIYAARANLKPFMFAGYQAGG
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCC
LPGGQLMTTTEVENFPGFPDGITGPQLMDRMKLQALRWGSEIVTEDVISVDFQQFPFVIQ
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCEEEE
SEERTVKAHSVVIATGATAKRLGLPSEKEFWSRGISACAICDGATPIFKNEELAVVGGGD
CCCCEEEEEEEEEECCCCHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCC
SAAEEAVYLTKYGSHVHLLVRSEQMRASKAMQDRVMRNPKVTVHWQTEVVDVFGDTQLQG
CHHHCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCEEC
LKIKNRQTAEIQELQVRGLFYAIGHQPNTQLFTQQLDLDKTGYILTQPDSVSTNIFGVFA
EEECCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEE
AGDVQEHEFRQAITAAGTGCMAALLAERWLSSQDLINEFHQSEASEQTEDGTHPPEYKLS
ECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
AAFDPNTTRHQGAFALRKLFHESDRIIVVKYASPTCGPCHILQPILSRVIDEFEGQVHYV
EECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
EIDIAEDPDIAESASITGTPTVQVFQDKSLLREFKGIKAKQAYRDAINELLAATS
EEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNGSKSQCSIRSRYLTVLMSEAIENLVVIGSGPAGYTAAIYAARANLKPFMFAGYQAGG
CCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCCEEEECCCCCC
LPGGQLMTTTEVENFPGFPDGITGPQLMDRMKLQALRWGSEIVTEDVISVDFQQFPFVIQ
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCEEEE
SEERTVKAHSVVIATGATAKRLGLPSEKEFWSRGISACAICDGATPIFKNEELAVVGGGD
CCCCEEEEEEEEEECCCCHHHCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCC
SAAEEAVYLTKYGSHVHLLVRSEQMRASKAMQDRVMRNPKVTVHWQTEVVDVFGDTQLQG
CHHHCEEEEEECCCEEEEEEECHHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCEEC
LKIKNRQTAEIQELQVRGLFYAIGHQPNTQLFTQQLDLDKTGYILTQPDSVSTNIFGVFA
EEECCCCCHHHHHHHHHEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEE
AGDVQEHEFRQAITAAGTGCMAALLAERWLSSQDLINEFHQSEASEQTEDGTHPPEYKLS
ECCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
AAFDPNTTRHQGAFALRKLFHESDRIIVVKYASPTCGPCHILQPILSRVIDEFEGQVHYV
EECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
EIDIAEDPDIAESASITGTPTVQVFQDKSLLREFKGIKAKQAYRDAINELLAATS
EEEECCCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]