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The map label for this gene is pqqL [C]

Identifier: 158337971

GI number: 158337971

Start: 4901089

End: 4902408

Strand: Reverse

Name: pqqL [C]

Synonym: AM1_4857

Alternate gene names: 158337971

Gene position: 4902408-4901089 (Counterclockwise)

Preceding gene: 158337972

Following gene: 158337969

Centisome position: 75.38

GC content: 52.12

Gene sequence:

>1320_bases
ATGCTGTCTCTCCCTGCTCCCACCGCTTCGGTTCCCGTTACTTCAGGATTACTCTGCCAGAAGTTTGAGTTAGCCAATGG
GCTGACGGTACTAATCACAGAAAACCCCATTGCAGATATCGTCTCAGCACGTATTTTCGTCGGGGCTGGTAGCACTCGTG
AGACCTCTGGGCAGGCCGGGCTTGCCTTCGTGATGGCGGCCACCCTTACCAAAGGGACCCACCGATTGTCCTCTGCTGAG
ATTGCTGAACAGGTGGAATCTGTCGGGGCCAGCTTAGGAGTTGAACGCGCGCCGGACTATTTCTTACTCAGCCTGAAAAC
CGTTTCTGAAGATTTCTTAGATATCCTGTCCCTGGCAGCTGAGTTACTCCAATTTCCGTCTTTTCCCCCATCTGAAGTGG
AGTTGGAAAAGAAGCTGGCCCTGCAATCGATTCGGTCTCAGCAAGAACAGCCCTTTACCTTGGCCCTGAAAGGACTTCGA
CAGTCCCTATTCCCCCCAGGCCATCCCTACACTCAAATCGGCCCCGGAGATCCTGACCAGATTGCTCAGCTTCAACCTGC
CGATCTGCATCAGTACCATCAGACCTATTTTCGGCCTGACAATATGGTGATTAGTCTCTCAGGGAATTTGCAGGCGGCTG
AGGCCGTGCACTATTGCCAGCAAATATTTGGAGATTGGCCCGTCCCAGAGCAGCCATTGCTTCCGCCTATTGGGTTACAG
CCAGTCAGCTCGATGGAGACTGGTTCAAATCTTGCCATAACGACACAACCGACCCAGCAAAGTATTGTCATGCTGGGGCA
TCTAGCCCCTTCAGTTCAGGAGCCGGACTATGTTGCCTTGAAGTTGCTGTATACCTACCTCTGTAGCGGTCTGTCTAGTC
GCTTGTTTGTGGAGCTGCGAGAAAAGCAGGGTCTAGCCTATGAGGTATCGGGGTTCTATCCGACTCGCTTAGGACCATCG
CATTTTGTTGTGTATTTGGGGACCGCTGCGGATAATACTGCGATCGCACTGGCGAAACTACAAGCTGAAATCCATCGCCT
AAGTCAACAGCCCCTGGCAGATGAGGCGCTAGAAACTGCCAAAAGTAAGCTGCTAGGACAATATGTTTTGGGCAAACAGA
GTAATGCCCAACTGGCTCATCTGATGGGCTGGTATGAAGCGCTGGGATTAGGGATTCACTATGATCAGACTTTCCCCAAA
CAGATTGCCAGCTTAGATGTTGAAACCGTCTATCAGGCTGCTGGTCAGCATCTGCAGCAATCCCATCTTTCCTTAGTCGG
GTCAGAGGCCGCTGTACAGCCTTGGCTCGCCCTGTCTTAA

Upstream 100 bases:

>100_bases
AGGCCCTTGAGCCCCCAACCTTGCAACATCTCGTTCACCAGTACTTGTCCCCAAGTCACTACGCCATCACCACCTTGCAA
CCCTGCTCTTATTGATCTGA

Downstream 100 bases:

>100_bases
TCGGCGGAATCTACTTTTTCTAAATATTGACTGCTGAGTAAATACGCGCCATTCTCCATGCGCACGCTCCAGTAATCCCC
CGGTTCTCGGCTGAGGACCG

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MLSLPAPTASVPVTSGLLCQKFELANGLTVLITENPIADIVSARIFVGAGSTRETSGQAGLAFVMAATLTKGTHRLSSAE
IAEQVESVGASLGVERAPDYFLLSLKTVSEDFLDILSLAAELLQFPSFPPSEVELEKKLALQSIRSQQEQPFTLALKGLR
QSLFPPGHPYTQIGPGDPDQIAQLQPADLHQYHQTYFRPDNMVISLSGNLQAAEAVHYCQQIFGDWPVPEQPLLPPIGLQ
PVSSMETGSNLAITTQPTQQSIVMLGHLAPSVQEPDYVALKLLYTYLCSGLSSRLFVELREKQGLAYEVSGFYPTRLGPS
HFVVYLGTAADNTAIALAKLQAEIHRLSQQPLADEALETAKSKLLGQYVLGKQSNAQLAHLMGWYEALGLGIHYDQTFPK
QIASLDVETVYQAAGQHLQQSHLSLVGSEAAVQPWLALS

Sequences:

>Translated_439_residues
MLSLPAPTASVPVTSGLLCQKFELANGLTVLITENPIADIVSARIFVGAGSTRETSGQAGLAFVMAATLTKGTHRLSSAE
IAEQVESVGASLGVERAPDYFLLSLKTVSEDFLDILSLAAELLQFPSFPPSEVELEKKLALQSIRSQQEQPFTLALKGLR
QSLFPPGHPYTQIGPGDPDQIAQLQPADLHQYHQTYFRPDNMVISLSGNLQAAEAVHYCQQIFGDWPVPEQPLLPPIGLQ
PVSSMETGSNLAITTQPTQQSIVMLGHLAPSVQEPDYVALKLLYTYLCSGLSSRLFVELREKQGLAYEVSGFYPTRLGPS
HFVVYLGTAADNTAIALAKLQAEIHRLSQQPLADEALETAKSKLLGQYVLGKQSNAQLAHLMGWYEALGLGIHYDQTFPK
QIASLDVETVYQAAGQHLQQSHLSLVGSEAAVQPWLALS
>Mature_439_residues
MLSLPAPTASVPVTSGLLCQKFELANGLTVLITENPIADIVSARIFVGAGSTRETSGQAGLAFVMAATLTKGTHRLSSAE
IAEQVESVGASLGVERAPDYFLLSLKTVSEDFLDILSLAAELLQFPSFPPSEVELEKKLALQSIRSQQEQPFTLALKGLR
QSLFPPGHPYTQIGPGDPDQIAQLQPADLHQYHQTYFRPDNMVISLSGNLQAAEAVHYCQQIFGDWPVPEQPLLPPIGLQ
PVSSMETGSNLAITTQPTQQSIVMLGHLAPSVQEPDYVALKLLYTYLCSGLSSRLFVELREKQGLAYEVSGFYPTRLGPS
HFVVYLGTAADNTAIALAKLQAEIHRLSQQPLADEALETAKSKLLGQYVLGKQSNAQLAHLMGWYEALGLGIHYDQTFPK
QIASLDVETVYQAAGQHLQQSHLSLVGSEAAVQPWLALS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=263, Percent_Identity=23.574144486692, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=219, Percent_Identity=24.6575342465753, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR007863 [H]

Pfam domain/function: PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47510; Mature: 47510

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLPAPTASVPVTSGLLCQKFELANGLTVLITENPIADIVSARIFVGAGSTRETSGQAG
CCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHEEEEECCCCCCCCCCCH
LAFVMAATLTKGTHRLSSAEIAEQVESVGASLGVERAPDYFLLSLKTVSEDFLDILSLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ELLQFPSFPPSEVELEKKLALQSIRSQQEQPFTLALKGLRQSLFPPGHPYTQIGPGDPDQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IAQLQPADLHQYHQTYFRPDNMVISLSGNLQAAEAVHYCQQIFGDWPVPEQPLLPPIGLQ
HHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PVSSMETGSNLAITTQPTQQSIVMLGHLAPSVQEPDYVALKLLYTYLCSGLSSRLFVELR
CCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
EKQGLAYEVSGFYPTRLGPSHFVVYLGTAADNTAIALAKLQAEIHRLSQQPLADEALETA
HHCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KSKLLGQYVLGKQSNAQLAHLMGWYEALGLGIHYDQTFPKQIASLDVETVYQAAGQHLQQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
SHLSLVGSEAAVQPWLALS
HHHHHHCCHHHHCCCCCCC
>Mature Secondary Structure
MLSLPAPTASVPVTSGLLCQKFELANGLTVLITENPIADIVSARIFVGAGSTRETSGQAG
CCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHEEEEECCCCCCCCCCCH
LAFVMAATLTKGTHRLSSAEIAEQVESVGASLGVERAPDYFLLSLKTVSEDFLDILSLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
ELLQFPSFPPSEVELEKKLALQSIRSQQEQPFTLALKGLRQSLFPPGHPYTQIGPGDPDQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IAQLQPADLHQYHQTYFRPDNMVISLSGNLQAAEAVHYCQQIFGDWPVPEQPLLPPIGLQ
HHCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PVSSMETGSNLAITTQPTQQSIVMLGHLAPSVQEPDYVALKLLYTYLCSGLSSRLFVELR
CCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
EKQGLAYEVSGFYPTRLGPSHFVVYLGTAADNTAIALAKLQAEIHRLSQQPLADEALETA
HHCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KSKLLGQYVLGKQSNAQLAHLMGWYEALGLGIHYDQTFPKQIASLDVETVYQAAGQHLQQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
SHLSLVGSEAAVQPWLALS
HHHHHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]