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The map label for this gene is dtd

Identifier: 158337684

GI number: 158337684

Start: 4602774

End: 4603229

Strand: Direct

Name: dtd

Synonym: AM1_4568

Alternate gene names: 158337684

Gene position: 4602774-4603229 (Clockwise)

Preceding gene: 158337681

Following gene: 158337685

Centisome position: 70.77

GC content: 44.74

Gene sequence:

>456_bases
ATGCGTATTATTTTGCAAAGAGTTAATGAATCACGAGTCGAAGTTGCAGGTCAAATTATTGGCAGAATTGAAAAAGGCCT
CAATTTATTAGTAGGAATTACCCCCTCGGATACAGACCAAGAAGTGGCTTGGATGGCTCGTAAATGCTTGGAACTGAGAA
TCTTTCCGGATCAGTCTGGAAAGCTGTCCCAGTCCGTCCAGGATATAGAGGGGGGATTATTAGTGATCAGCCAATTTACC
TTGTATGGAGATTGTCGAAAAGGACGGCGACCTTCCTTTGATAAAGCGGCACCTGGTGCTATGGCAGAACAGATTTATGA
GCAATTCGTGACCAAACTGAGAGCCAGCGGCTTACAGGTGGAAACGGGACAGTTTGGTGCCATGATGAACGTTTATATCG
AAAATGATGGTCCTGTGACGTTAATCTTAGAACGAGAGGCTGAGAGCGAAAGATAG

Upstream 100 bases:

>100_bases
TCACGGGAAGGTCTGAGGGCTGTGCCTTCCACAACCTAGCTGTAACTAGCTCTCCTGCTTGAATTACTGCAAATTAACTA
CATATATCTCCTTAAATCTG

Downstream 100 bases:

>100_bases
GAATAACCTTCTTGACTTTGATTTGAATTCTGGTTCGATGGCGCTCTCAAACCAACAGATACCAAAGATAGATACCGTTA
GGGATTGCCATTTCTAGCAG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRIILQRVNESRVEVAGQIIGRIEKGLNLLVGITPSDTDQEVAWMARKCLELRIFPDQSGKLSQSVQDIEGGLLVISQFT
LYGDCRKGRRPSFDKAAPGAMAEQIYEQFVTKLRASGLQVETGQFGAMMNVYIENDGPVTLILEREAESER

Sequences:

>Translated_151_residues
MRIILQRVNESRVEVAGQIIGRIEKGLNLLVGITPSDTDQEVAWMARKCLELRIFPDQSGKLSQSVQDIEGGLLVISQFT
LYGDCRKGRRPSFDKAAPGAMAEQIYEQFVTKLRASGLQVETGQFGAMMNVYIENDGPVTLILEREAESER
>Mature_151_residues
MRIILQRVNESRVEVAGQIIGRIEKGLNLLVGITPSDTDQEVAWMARKCLELRIFPDQSGKLSQSVQDIEGGLLVISQFT
LYGDCRKGRRPSFDKAAPGAMAEQIYEQFVTKLRASGLQVETGQFGAMMNVYIENDGPVTLILEREAESER

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:
GO:0005737: D-tyrosyl-tRNA(Tyr) deacylase
GO:0016787: D-tyrosyl-tRNA(Tyr) deacylase
GO:0016788: D-tyrosyl-tRNA(Tyr) deacylase
GO:0019478: D-tyrosyl-tRNA(Tyr) deacylase

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=43.7086092715232, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=40.9722222222222, Blast_Score=114, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=36.9127516778523, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319982, Length=149, Percent_Identity=39.5973154362416, Blast_Score=118, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=43.1506849315069, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_ACAM1 (B0BZ98)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001518860.1
- ProteinModelPortal:   B0BZ98
- SMR:   B0BZ98
- GeneID:   5683370
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4568
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   AMAR329726:AM1_4568-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16833; Mature: 16833

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILQRVNESRVEVAGQIIGRIEKGLNLLVGITPSDTDQEVAWMARKCLELRIFPDQSG
CCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCCCCC
KLSQSVQDIEGGLLVISQFTLYGDCRKGRRPSFDKAAPGAMAEQIYEQFVTKLRASGLQV
CHHHHHHHHCCCEEEEEHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGQFGAMMNVYIENDGPVTLILEREAESER
ECCCCCEEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRIILQRVNESRVEVAGQIIGRIEKGLNLLVGITPSDTDQEVAWMARKCLELRIFPDQSG
CCCEEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCCCCC
KLSQSVQDIEGGLLVISQFTLYGDCRKGRRPSFDKAAPGAMAEQIYEQFVTKLRASGLQV
CHHHHHHHHCCCEEEEEHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGQFGAMMNVYIENDGPVTLILEREAESER
ECCCCCEEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA