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The map label for this gene is ubiE [C]

Identifier: 158337401

GI number: 158337401

Start: 4298542

End: 4299171

Strand: Direct

Name: ubiE [C]

Synonym: AM1_4280

Alternate gene names: 158337401

Gene position: 4298542-4299171 (Clockwise)

Preceding gene: 158337400

Following gene: 158337403

Centisome position: 66.09

GC content: 46.67

Gene sequence:

>630_bases
ATGGTATCCAAATTACACGCTTTTTTGGCACAGCAGCTCGGACATCCCTCTGGTATATGGGGGCGACTCCTACTGCGATT
ACTCAATCGAGAAAATGCCGGGATGAATCGGTTGGCCTTTGAGCAACTGGCGATACGTCAGGGCGATCGCATCCTAGAAA
TTGGATTTGGTGGGGGCAGTTTGCTGGCTCGTATCTTAGCAACAGGTCTACCCAAAACAGTGGTTGGACTGGACTATGCG
GAAGATGCTCTGACTGTCACCCAGCGAAAATTATGGCGATATGTTCATTCAGGCCAACTGACGCTACAGCAAGGCAATGC
CAGCCATCTTCCGTTCCCGGACCAGCAGTTTGATCATATTTGTACGGTCAATACTCTCTACTTTTGGCCGGATGCTCAAA
CTGTGTTTCAAGAATGCTATCGCGTGTTAACACCGTCAGGAACAGTGGTCGTTTGTTACAACACCAAAGACTTTCTGGAA
CAACAAGGGTTAACTCAGCAAGGATTTAAGGGATATGAGGTGAAAACGGTGGAAAAGTTTTTGGATGAAATTGGATTTCA
GTCAATAGAAACCTTCTCTAGACAGGATTCCAGTAATGGCCAATATCATTGCACCTGTGGAAAACGGTGA

Upstream 100 bases:

>100_bases
CGCCCTTGGAGAAGAAACGTTATCAATATTCAAAAGCACTTGTGAAACACTGGGTTCAACACAGAGCACTTCGGTGAATC
ATGTGATGAGAGAACCACAA

Downstream 100 bases:

>100_bases
CATTGAACCTAAGTCCAGACTGTAAATACATAAACAAAATAAGCCCCATATAAAGCCCCCATGATTCCCAGGGCAATGCG
ACCTTTTAGGGATCGATAGT

Product: UbiE/COQ5 family methlytransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase UbiE/COQ5 Family; Methyltransferase Domain Protein; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; SAM-Dependent Methyltransferase UbiE Family; Methyltransferase Domain-Containing Protein; UbiE/COQ5 Methyltransferase; Methyl Transferase; UbiE/COQ5 Family Methlytransferase; Sam-Dependent Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Multidrug Resistance Protein; Methyltransferase Domain Family; SAM Dependent Methyltransferase YrrH; UbiE/COQ5 Family Methyltransferase

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MVSKLHAFLAQQLGHPSGIWGRLLLRLLNRENAGMNRLAFEQLAIRQGDRILEIGFGGGSLLARILATGLPKTVVGLDYA
EDALTVTQRKLWRYVHSGQLTLQQGNASHLPFPDQQFDHICTVNTLYFWPDAQTVFQECYRVLTPSGTVVVCYNTKDFLE
QQGLTQQGFKGYEVKTVEKFLDEIGFQSIETFSRQDSSNGQYHCTCGKR

Sequences:

>Translated_209_residues
MVSKLHAFLAQQLGHPSGIWGRLLLRLLNRENAGMNRLAFEQLAIRQGDRILEIGFGGGSLLARILATGLPKTVVGLDYA
EDALTVTQRKLWRYVHSGQLTLQQGNASHLPFPDQQFDHICTVNTLYFWPDAQTVFQECYRVLTPSGTVVVCYNTKDFLE
QQGLTQQGFKGYEVKTVEKFLDEIGFQSIETFSRQDSSNGQYHCTCGKR
>Mature_209_residues
MVSKLHAFLAQQLGHPSGIWGRLLLRLLNRENAGMNRLAFEQLAIRQGDRILEIGFGGGSLLARILATGLPKTVVGLDYA
EDALTVTQRKLWRYVHSGQLTLQQGNASHLPFPDQQFDHICTVNTLYFWPDAQTVFQECYRVLTPSGTVVVCYNTKDFLE
QQGLTQQGFKGYEVKTVEKFLDEIGFQSIETFSRQDSSNGQYHCTCGKR

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 23575; Mature: 23575

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKLHAFLAQQLGHPSGIWGRLLLRLLNRENAGMNRLAFEQLAIRQGDRILEIGFGGGS
CCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHH
LLARILATGLPKTVVGLDYAEDALTVTQRKLWRYVHSGQLTLQQGNASHLPFPDQQFDHI
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCE
CTVNTLYFWPDAQTVFQECYRVLTPSGTVVVCYNTKDFLEQQGLTQQGFKGYEVKTVEKF
EEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHH
LDEIGFQSIETFSRQDSSNGQYHCTCGKR
HHHHCHHHHHHHHHCCCCCCCEEEECCCC
>Mature Secondary Structure
MVSKLHAFLAQQLGHPSGIWGRLLLRLLNRENAGMNRLAFEQLAIRQGDRILEIGFGGGS
CCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHH
LLARILATGLPKTVVGLDYAEDALTVTQRKLWRYVHSGQLTLQQGNASHLPFPDQQFDHI
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCE
CTVNTLYFWPDAQTVFQECYRVLTPSGTVVVCYNTKDFLEQQGLTQQGFKGYEVKTVEKF
EEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCCCCCCHHHHHHH
LDEIGFQSIETFSRQDSSNGQYHCTCGKR
HHHHCHHHHHHHHHCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA