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The map label for this gene is arcB [H]

Identifier: 158337403

GI number: 158337403

Start: 4299928

End: 4302300

Strand: Direct

Name: arcB [H]

Synonym: AM1_4282

Alternate gene names: 158337403

Gene position: 4299928-4302300 (Clockwise)

Preceding gene: 158337401

Following gene: 158337406

Centisome position: 66.11

GC content: 49.09

Gene sequence:

>2373_bases
TTGTCTGTTCCCTCTCTTCCTTCTCTGAATAAGTCTCCCCAGAACAAGCGGCGTTTAAGGGGTCGCTTTCTCATTGGCGG
AATTACCCTCGTGGTTGGCGTCGCAGCCTACTATAGCTATCGGATTGTTCGAGAATTATTGTTAGATAACCTCAAAAATA
ATGCCCTGCTCCAAGTCCAGCAGGGGAACCAGGAGTTGAATCAATGGTTAGTGGCGCGTAAAACCGAAGCCGCCACCCTC
GCCAATACCCCTAGCCTGCGGACGATGGATTGGGGAACGGTGGGACCTTTTCTCAAACCAGAGAAACAGCGCCTCGAGCA
TTTTTACTATTTATCGATGATCTCTCCTGATGGGTCTTACTACAGCACCAAAGGAGGAAAAGCTATAGGGAAAAATCTTA
AGGACCGTAAGCATGTCCAACTTTCTTTGAAAGGGCAAACCTATGTGTCCGATCCGGTCATTTCTCGGACGGCTGAGGGA
ACGATTGTGGCAGTGACGACGCCCATTCGACAAACGCCCCAATCCGAGAGTCCTGTTATTGGTGTTTTGGCAGGACTAAT
TGATATCCACTGCTTGGAGAAGGTGGTTCAAGGATTGGAGTACGGGTCAGGTAGTTATGCGTTTGCTCTGAACTCGGAAG
GCATGCCCATTGTCCATCCTGATCAGTCATTGATGAGTACGATTAATGATCAAAACCCCACTAGTTTATTGGAGGCCAAG
GATCAAAACTTAGCTGCGATCTCACAGCGGATGGTGGCTCGTTCCCAAGGGATTGAACTCACTCGGATTAATAATCAGGC
TGTATATGTCGCCTACTTGCCCTTAGCGGAGGCAGACTGGTCGATTGCCTTAGTGATTCCCCAAGGCAATATCGAGTCTC
AGCTACAGCTCCTAGATCTGATTGCGATGGTGTTGGTCGGCTTAATCGTGGCCATGCTGATCTTGTTATGGCGGGTACAG
ACCTTTGAACGTATTCAACTCCAACGCACGGCTGATTTAGCTGCAGCTGCCAATCAGGCTAAAAGCGAGTTTCTCTCCAA
TATGAGCCACGAGTTAAGAACGCCCCTCAATGCCATTCTGGGATTTAGCCAGCTTTTGCAGCAAGACCCTCAAATCCCTC
CACACCAGCAAAAACAGCTCGACATCATTAACCAAAGTGGCACTCACCTACTGGCGCTGATTAACGACATTTTGGAGATG
TCGAAAATTGAGGCGGGATTTAGCACCTTAAAACAGAGTCCGATTGAGTTGCAGGAGTTGCTGGACAGTGTAAAGGCGAT
GATGGAGCTCAAAGCAACCGCTAAGCAGCTCGGGTTCGAGTTTGTCTATAGCCCTGCCCTGCCTCAATTTATTGAGGTCG
ATGCTGGGAAGGTGCGCCAAATTCTGATGAATCTCCTCAGTAATGCCATTAAGTTTACGCAAAAGGGCTATGTCTCCTTA
ACGGTGGATGCGATTTATCCCGCTTCAGACTCATCTGGCCTGATGCAATTGCGTTTTGCTGTTAAAGACACGGGATTAGG
GATTGCCCCCGAGGAAATTGAACAGCTCTTTACCCCCTTTGTGCAGACTGCTTCAGGACGAATAACACAAATGGGAACGG
GTTTAGGCTTGGCTCTGAGTCGCAAGTTTGCTCAGCTGATGAAGGGCGATATTACCGTGGACAGTGTTGTTGACCAAGGC
AGTACGTTTACTTGTTGGATTGAAGTCCAACAAATTGGCAGTGCGGTCCCCTCCCAGGTTTTTCCACAGATCAAAGGGTT
AGCCCCAGGTCAAGCTCCTGTACGCATGTTGGTGGCAGAAGATCAGTGGGACAGTCGTGCCGTGCTAGCCCAACTGCTGC
AATCTGTCGGCTTTGAAGTGGCTGAAGCTGCCAATGGCGAAGAAGCGGTGCGACTGGTTCAGTCTTGGCACCCCCATCTT
GTGTGGATGGATATGAGAATGCCAGTTCTGGATGGCTTGGCTGCAACGCAACAGATTAAAGCCCGATCTCAGCCTCCGAT
TATTATTGCGCTGACCGCGAATGCGTTTGTTGAAGATCGGCAAGAGGCATTAAGGGTGGGCTGTGACGATTTTGTCGCTA
AACCCTACCAAATTGAACAAATTTACGCCAAAATCGCAGAGCATTTAGGAGTCCAATACGAGGTTGTGACGCCTGATCAG
CCCAGCCATAGCGAAACTACCTCTCAAGAGATCAGCTTGCACTGTATGCCCGCGACGTGGCGATCGCAATTGCAGGAGAC
GGCTCAATGTTTAGATCAACTGGGTGTTCATCAACTGTTGGAAGAGATCCCCGAGCAACATCAAGCCCTAAAAGTAAGGC
TAGAACAGTTAGTTCAAGACTTTCGTTTCGATCTGATTTGTCAGCTGGTTTAA

Upstream 100 bases:

>100_bases
TAGCGGGAATCCTAAGTAAAGTGGGAGCTCAGCAGAAATAACGATGAACGGTGTACCGTTCGCCTAGTCATAAATTGTCA
CCCATACTTCCCCTCCCCAA

Downstream 100 bases:

>100_bases
AGGATTATTGGGGCTTCCATTCGTGGAGATTGCGCTTGAGAAATACGCTAAAAATAGCGCTATTTGTAAGTCGGAAAAAC
GACGTAAATCTTGCGATTAC

Product: two-component hybrid sensor and regulator histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MSVPSLPSLNKSPQNKRRLRGRFLIGGITLVVGVAAYYSYRIVRELLLDNLKNNALLQVQQGNQELNQWLVARKTEAATL
ANTPSLRTMDWGTVGPFLKPEKQRLEHFYYLSMISPDGSYYSTKGGKAIGKNLKDRKHVQLSLKGQTYVSDPVISRTAEG
TIVAVTTPIRQTPQSESPVIGVLAGLIDIHCLEKVVQGLEYGSGSYAFALNSEGMPIVHPDQSLMSTINDQNPTSLLEAK
DQNLAAISQRMVARSQGIELTRINNQAVYVAYLPLAEADWSIALVIPQGNIESQLQLLDLIAMVLVGLIVAMLILLWRVQ
TFERIQLQRTADLAAAANQAKSEFLSNMSHELRTPLNAILGFSQLLQQDPQIPPHQQKQLDIINQSGTHLLALINDILEM
SKIEAGFSTLKQSPIELQELLDSVKAMMELKATAKQLGFEFVYSPALPQFIEVDAGKVRQILMNLLSNAIKFTQKGYVSL
TVDAIYPASDSSGLMQLRFAVKDTGLGIAPEEIEQLFTPFVQTASGRITQMGTGLGLALSRKFAQLMKGDITVDSVVDQG
STFTCWIEVQQIGSAVPSQVFPQIKGLAPGQAPVRMLVAEDQWDSRAVLAQLLQSVGFEVAEAANGEEAVRLVQSWHPHL
VWMDMRMPVLDGLAATQQIKARSQPPIIIALTANAFVEDRQEALRVGCDDFVAKPYQIEQIYAKIAEHLGVQYEVVTPDQ
PSHSETTSQEISLHCMPATWRSQLQETAQCLDQLGVHQLLEEIPEQHQALKVRLEQLVQDFRFDLICQLV

Sequences:

>Translated_790_residues
MSVPSLPSLNKSPQNKRRLRGRFLIGGITLVVGVAAYYSYRIVRELLLDNLKNNALLQVQQGNQELNQWLVARKTEAATL
ANTPSLRTMDWGTVGPFLKPEKQRLEHFYYLSMISPDGSYYSTKGGKAIGKNLKDRKHVQLSLKGQTYVSDPVISRTAEG
TIVAVTTPIRQTPQSESPVIGVLAGLIDIHCLEKVVQGLEYGSGSYAFALNSEGMPIVHPDQSLMSTINDQNPTSLLEAK
DQNLAAISQRMVARSQGIELTRINNQAVYVAYLPLAEADWSIALVIPQGNIESQLQLLDLIAMVLVGLIVAMLILLWRVQ
TFERIQLQRTADLAAAANQAKSEFLSNMSHELRTPLNAILGFSQLLQQDPQIPPHQQKQLDIINQSGTHLLALINDILEM
SKIEAGFSTLKQSPIELQELLDSVKAMMELKATAKQLGFEFVYSPALPQFIEVDAGKVRQILMNLLSNAIKFTQKGYVSL
TVDAIYPASDSSGLMQLRFAVKDTGLGIAPEEIEQLFTPFVQTASGRITQMGTGLGLALSRKFAQLMKGDITVDSVVDQG
STFTCWIEVQQIGSAVPSQVFPQIKGLAPGQAPVRMLVAEDQWDSRAVLAQLLQSVGFEVAEAANGEEAVRLVQSWHPHL
VWMDMRMPVLDGLAATQQIKARSQPPIIIALTANAFVEDRQEALRVGCDDFVAKPYQIEQIYAKIAEHLGVQYEVVTPDQ
PSHSETTSQEISLHCMPATWRSQLQETAQCLDQLGVHQLLEEIPEQHQALKVRLEQLVQDFRFDLICQLV
>Mature_789_residues
SVPSLPSLNKSPQNKRRLRGRFLIGGITLVVGVAAYYSYRIVRELLLDNLKNNALLQVQQGNQELNQWLVARKTEAATLA
NTPSLRTMDWGTVGPFLKPEKQRLEHFYYLSMISPDGSYYSTKGGKAIGKNLKDRKHVQLSLKGQTYVSDPVISRTAEGT
IVAVTTPIRQTPQSESPVIGVLAGLIDIHCLEKVVQGLEYGSGSYAFALNSEGMPIVHPDQSLMSTINDQNPTSLLEAKD
QNLAAISQRMVARSQGIELTRINNQAVYVAYLPLAEADWSIALVIPQGNIESQLQLLDLIAMVLVGLIVAMLILLWRVQT
FERIQLQRTADLAAAANQAKSEFLSNMSHELRTPLNAILGFSQLLQQDPQIPPHQQKQLDIINQSGTHLLALINDILEMS
KIEAGFSTLKQSPIELQELLDSVKAMMELKATAKQLGFEFVYSPALPQFIEVDAGKVRQILMNLLSNAIKFTQKGYVSLT
VDAIYPASDSSGLMQLRFAVKDTGLGIAPEEIEQLFTPFVQTASGRITQMGTGLGLALSRKFAQLMKGDITVDSVVDQGS
TFTCWIEVQQIGSAVPSQVFPQIKGLAPGQAPVRMLVAEDQWDSRAVLAQLLQSVGFEVAEAANGEEAVRLVQSWHPHLV
WMDMRMPVLDGLAATQQIKARSQPPIIIALTANAFVEDRQEALRVGCDDFVAKPYQIEQIYAKIAEHLGVQYEVVTPDQP
SHSETTSQEISLHCMPATWRSQLQETAQCLDQLGVHQLLEEIPEQHQALKVRLEQLVQDFRFDLICQLV

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=406, Percent_Identity=33.9901477832512, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1788713, Length=399, Percent_Identity=30.3258145363409, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081816, Length=432, Percent_Identity=30.787037037037, Blast_Score=172, Evalue=8e-44,
Organism=Escherichia coli, GI1789149, Length=257, Percent_Identity=36.9649805447471, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI145693157, Length=400, Percent_Identity=32.25, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1790436, Length=322, Percent_Identity=25.4658385093168, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=26.8722466960352, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=327, Percent_Identity=25.6880733944954, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=278, Percent_Identity=28.4172661870504, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=36.4485981308411, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789809, Length=137, Percent_Identity=32.8467153284672, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=27.6497695852535, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=363, Percent_Identity=22.8650137741047, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87368; Mature: 87237

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPSLPSLNKSPQNKRRLRGRFLIGGITLVVGVAAYYSYRIVRELLLDNLKNNALLQVQ
CCCCCCCCCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
QGNQELNQWLVARKTEAATLANTPSLRTMDWGTVGPFLKPEKQRLEHFYYLSMISPDGSY
CCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCE
YSTKGGKAIGKNLKDRKHVQLSLKGQTYVSDPVISRTAEGTIVAVTTPIRQTPQSESPVI
EECCCCHHHHCCCCCCCEEEEEECCCEEECCCHHHCCCCCEEEEEECCCCCCCCCCCCHH
GVLAGLIDIHCLEKVVQGLEYGSGSYAFALNSEGMPIVHPDQSLMSTINDQNPTSLLEAK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCHHHHHHHCCCCCHHHHHCC
DQNLAAISQRMVARSQGIELTRINNQAVYVAYLPLAEADWSIALVIPQGNIESQLQLLDL
CCHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
IAMVLVGLIVAMLILLWRVQTFERIQLQRTADLAAAANQAKSEFLSNMSHELRTPLNAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFSQLLQQDPQIPPHQQKQLDIINQSGTHLLALINDILEMSKIEAGFSTLKQSPIELQEL
HHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LDSVKAMMELKATAKQLGFEFVYSPALPQFIEVDAGKVRQILMNLLSNAIKFTQKGYVSL
HHHHHHHHHHHHHHHHCCHHEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
TVDAIYPASDSSGLMQLRFAVKDTGLGIAPEEIEQLFTPFVQTASGRITQMGTGLGLALS
EEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
RKFAQLMKGDITVDSVVDQGSTFTCWIEVQQIGSAVPSQVFPQIKGLAPGQAPVRMLVAE
HHHHHHHCCCCCHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEC
DQWDSRAVLAQLLQSVGFEVAEAANGEEAVRLVQSWHPHLVWMDMRMPVLDGLAATQQIK
CCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
ARSQPPIIIALTANAFVEDRQEALRVGCDDFVAKPYQIEQIYAKIAEHLGVQYEVVTPDQ
HCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCC
PSHSETTSQEISLHCMPATWRSQLQETAQCLDQLGVHQLLEEIPEQHQALKVRLEQLVQD
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRFDLICQLV
HHHHHHHHCC
>Mature Secondary Structure 
SVPSLPSLNKSPQNKRRLRGRFLIGGITLVVGVAAYYSYRIVRELLLDNLKNNALLQVQ
CCCCCCCCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
QGNQELNQWLVARKTEAATLANTPSLRTMDWGTVGPFLKPEKQRLEHFYYLSMISPDGSY
CCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCE
YSTKGGKAIGKNLKDRKHVQLSLKGQTYVSDPVISRTAEGTIVAVTTPIRQTPQSESPVI
EECCCCHHHHCCCCCCCEEEEEECCCEEECCCHHHCCCCCEEEEEECCCCCCCCCCCCHH
GVLAGLIDIHCLEKVVQGLEYGSGSYAFALNSEGMPIVHPDQSLMSTINDQNPTSLLEAK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCHHHHHHHCCCCCHHHHHCC
DQNLAAISQRMVARSQGIELTRINNQAVYVAYLPLAEADWSIALVIPQGNIESQLQLLDL
CCHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHH
IAMVLVGLIVAMLILLWRVQTFERIQLQRTADLAAAANQAKSEFLSNMSHELRTPLNAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFSQLLQQDPQIPPHQQKQLDIINQSGTHLLALINDILEMSKIEAGFSTLKQSPIELQEL
HHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LDSVKAMMELKATAKQLGFEFVYSPALPQFIEVDAGKVRQILMNLLSNAIKFTQKGYVSL
HHHHHHHHHHHHHHHHCCHHEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEE
TVDAIYPASDSSGLMQLRFAVKDTGLGIAPEEIEQLFTPFVQTASGRITQMGTGLGLALS
EEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHH
RKFAQLMKGDITVDSVVDQGSTFTCWIEVQQIGSAVPSQVFPQIKGLAPGQAPVRMLVAE
HHHHHHHCCCCCHHHHHCCCCEEEEEEEHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEC
DQWDSRAVLAQLLQSVGFEVAEAANGEEAVRLVQSWHPHLVWMDMRMPVLDGLAATQQIK
CCCCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
ARSQPPIIIALTANAFVEDRQEALRVGCDDFVAKPYQIEQIYAKIAEHLGVQYEVVTPDQ
HCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCC
PSHSETTSQEISLHCMPATWRSQLQETAQCLDQLGVHQLLEEIPEQHQALKVRLEQLVQD
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRFDLICQLV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]