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The map label for this gene is 158337173

Identifier: 158337173

GI number: 158337173

Start: 4093383

End: 4093775

Strand: Reverse

Name: 158337173

Synonym: AM1_4050

Alternate gene names: NA

Gene position: 4093775-4093383 (Counterclockwise)

Preceding gene: 158337174

Following gene: 158337171

Centisome position: 62.95

GC content: 47.84

Gene sequence:

>393_bases
ATGTCACCTTGGCCAGCGTTAATCAGCTTGCTTGCGTTATTACTATATTTTGTGGTCACCATTAATGTGGGGCGTGCCCG
AGCAAAATATGGCATTCCAGCCCCTCAAATGTTTGGCAATCCTGATTTTGAGCGGGTGTTACGAGTCCAGCAAAATATGC
TGGAGCAGCTAATTTTTTTCTTGCCGGCTCTATGGATCTTCTGTTTCTATCTCAATCCGCTATGGGGATCGGGATTAGGC
ATACTCTGGGTAGTTGGACGTGCTCTTTATGCTTGGGGATATTATCAGGCCGCCGAGAAACGAGGTCCTGGCTTTGCTAT
TGCGTCTTTAAGCAGTCTAGTGCTGGTCCTAGCAGGGCTAGTCGGTGTTGTCTTAGCCTTGATACCTGCCTAA

Upstream 100 bases:

>100_bases
AAAGATTGCGTCTTTTTTCTTCCCAAGACGAACATATCGCCATTCTGAATCTGAAACCCTACAAATTGCCTAAACCTAAT
CAAATAGAGGAGTATTGTTG

Downstream 100 bases:

>100_bases
CTTCACAGCCTCTTACACAACCCATTGACTTAAGGAGTGGCAAAACTGCTCTAGGTCTAAGGCATGAATGCGTTGATCCT
GCTGGGCACGTTTGCGATCT

Product: microsomal glutathione S-transferase 2

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MSPWPALISLLALLLYFVVTINVGRARAKYGIPAPQMFGNPDFERVLRVQQNMLEQLIFFLPALWIFCFYLNPLWGSGLG
ILWVVGRALYAWGYYQAAEKRGPGFAIASLSSLVLVLAGLVGVVLALIPA

Sequences:

>Translated_130_residues
MSPWPALISLLALLLYFVVTINVGRARAKYGIPAPQMFGNPDFERVLRVQQNMLEQLIFFLPALWIFCFYLNPLWGSGLG
ILWVVGRALYAWGYYQAAEKRGPGFAIASLSSLVLVLAGLVGVVLALIPA
>Mature_129_residues
SPWPALISLLALLLYFVVTINVGRARAKYGIPAPQMFGNPDFERVLRVQQNMLEQLIFFLPALWIFCFYLNPLWGSGLGI
LWVVGRALYAWGYYQAAEKRGPGFAIASLSSLVLVLAGLVGVVLALIPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MAPEG family [H]

Homologues:

Organism=Homo sapiens, GI4505181, Length=103, Percent_Identity=39.8058252427184, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001129 [H]

Pfam domain/function: PF01124 MAPEG [H]

EC number: 2.5.1.18

Molecular weight: Translated: 14341; Mature: 14210

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPWPALISLLALLLYFVVTINVGRARAKYGIPAPQMFGNPDFERVLRVQQNMLEQLIFF
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHH
LPALWIFCFYLNPLWGSGLGILWVVGRALYAWGYYQAAEKRGPGFAIASLSSLVLVLAGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGVVLALIPA
HHHHHHHHCC
>Mature Secondary Structure 
SPWPALISLLALLLYFVVTINVGRARAKYGIPAPQMFGNPDFERVLRVQQNMLEQLIFF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHH
LPALWIFCFYLNPLWGSGLGILWVVGRALYAWGYYQAAEKRGPGFAIASLSSLVLVLAGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGVVLALIPA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]