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The map label for this gene is hlyD [H]

Identifier: 158337136

GI number: 158337136

Start: 4059349

End: 4060902

Strand: Reverse

Name: hlyD [H]

Synonym: AM1_4011

Alternate gene names: 158337136

Gene position: 4060902-4059349 (Counterclockwise)

Preceding gene: 158337137

Following gene: 158337135

Centisome position: 62.44

GC content: 37.64

Gene sequence:

>1554_bases
TTGGGGGCAAAGGTTTTGACTATTTCTGATCAAGAATTAGGCAAAAAAAACGATCAAAGATCAAGCTTAAATCAGCCTAA
AATACAAAATTTTGTATATAAAAACAATGACATTATTGATTGGTCTGCATCATTACAATCACTCCTAGATCAGCCTCCGG
CAGAGATGCCTCTCCGAATTATTTCGAGCGGATTAGTATTCTTACTTGCTTTTCTCGGCTGGGCTTGGCTAGGAAAAATA
GAAGATATAGGGACGGCAAAAGGAAAGCTAGTCCCAAAAGGTGAGACATATAAGGTTGAATCTGTTGCTATCGGGAAGGT
CAGCAGAATTGCGGTTAAAGAAGGAGAAACTGTTGCGGCTGGACAAGTCATTGCTGAACTAGATACTTCTTTAGATAAAA
AAGAAGTCAAGCGATTAGAACAAATGCTGTCTAGCTACCAACAAGAGCTAAAGCAAAAACAATCTCTACTCAATAAAGTT
TACTTAGAAGCTCAAACTCATCAACGAATTTCTACCTCAGAGAATTTGGGTCAAGAGTCTGCCATAAAATCAGCTGAAGA
TAGGGCAGATACTCTACTTCAGTTGCTAATACAACAAAAGCAAGAGCTTAATGCTTACAATGCCAGGCATAAACGCTTAA
AACTCTTGTCAAACTTATCAAGATCCCGAGTAAAGCAATTAGAGCTAGACCTCAAATCCAATCAAGGTCGTGTGAAAAAA
TTAAAGTCTTTGAAAAAGCAAGGTGCTATCTCTAGCGAGTTAGTCTTCCAGGCCAATCAAAATCTTAGTCAAGTTCAGAG
TCAGATCACAGAAAGTAAATTACAAGACATTACTAGTGTCAGCCAGCAAATCTTTCAAAATGAGCAATCGATGCGAACTC
TTGCTGCAAAAATGACACAAGATCAAGGAGAGCTCTATTCTGCTTATCGACAAGTTGAACAACTAAAGGCAGAGTTAAAT
CGGAATAAAGCGGAAAGAACTCGACTAAAGCTAGAAGCATACCAAAAAATTGACCAGCTTAAACTAGAAACCACCCAGGC
AAAAACTAAAGTATCTGAAACCAAGAATCAGATGCTCAAAGCCAAAGCGACTCTAGACCAAAAGCTCTTTAAAGCACCTA
TTGATGGTGTTGTTTTATCATTTAATTTAAAGAATGAAGGTAAGGTAGTCAATTCAGGGCAAACTGTAGCTGAAATTGCA
CCTCACAACACTCCTTTAATAATTTCTGCAGTTTTACCCAATAAGGAAGCAGGCTTTATAAAAAAGGATCAGCCAGCGAA
AGTCAAATTTGATGCCTATTCATATCAAGATTATGGGGTAGTACCAGGTAAGGTATCTTCAATTTCATCAGACTCAAAAT
ATGATCCGAAGCTAGGAAATGTTTACCAAGTTGAAGTTGAATTAGAGCGTCATCACATCGTAGATAATAACAAGAGAATT
AAATTTAGACCTGGCCAATCGGCAACAGCTAATATTGTTATCCGTCAGCGTCGTATTATCGATGTTTTATTAGATCCAAT
CAAGCAACTGAAGAGTGGCAATACGAAAAAATAA

Upstream 100 bases:

>100_bases
AATATTAAATTTTTGATGCATCTAAATCATTTTCTGTCTAAAATAAAAATGTTTTGACCAATAATCTGCGATAAAGTAGA
ATATTTTTTACAAAAAGGTT

Downstream 100 bases:

>100_bases
CATTGCTTGAATTCTCATCTCTTAATCAATGAATAGAATACATCATCTTCTTTCAGTCATCTCCGGCTACTGAACAGTCT
TCGAGTGGTTTTCATCCTAA

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MGAKVLTISDQELGKKNDQRSSLNQPKIQNFVYKNNDIIDWSASLQSLLDQPPAEMPLRIISSGLVFLLAFLGWAWLGKI
EDIGTAKGKLVPKGETYKVESVAIGKVSRIAVKEGETVAAGQVIAELDTSLDKKEVKRLEQMLSSYQQELKQKQSLLNKV
YLEAQTHQRISTSENLGQESAIKSAEDRADTLLQLLIQQKQELNAYNARHKRLKLLSNLSRSRVKQLELDLKSNQGRVKK
LKSLKKQGAISSELVFQANQNLSQVQSQITESKLQDITSVSQQIFQNEQSMRTLAAKMTQDQGELYSAYRQVEQLKAELN
RNKAERTRLKLEAYQKIDQLKLETTQAKTKVSETKNQMLKAKATLDQKLFKAPIDGVVLSFNLKNEGKVVNSGQTVAEIA
PHNTPLIISAVLPNKEAGFIKKDQPAKVKFDAYSYQDYGVVPGKVSSISSDSKYDPKLGNVYQVEVELERHHIVDNNKRI
KFRPGQSATANIVIRQRRIIDVLLDPIKQLKSGNTKK

Sequences:

>Translated_517_residues
MGAKVLTISDQELGKKNDQRSSLNQPKIQNFVYKNNDIIDWSASLQSLLDQPPAEMPLRIISSGLVFLLAFLGWAWLGKI
EDIGTAKGKLVPKGETYKVESVAIGKVSRIAVKEGETVAAGQVIAELDTSLDKKEVKRLEQMLSSYQQELKQKQSLLNKV
YLEAQTHQRISTSENLGQESAIKSAEDRADTLLQLLIQQKQELNAYNARHKRLKLLSNLSRSRVKQLELDLKSNQGRVKK
LKSLKKQGAISSELVFQANQNLSQVQSQITESKLQDITSVSQQIFQNEQSMRTLAAKMTQDQGELYSAYRQVEQLKAELN
RNKAERTRLKLEAYQKIDQLKLETTQAKTKVSETKNQMLKAKATLDQKLFKAPIDGVVLSFNLKNEGKVVNSGQTVAEIA
PHNTPLIISAVLPNKEAGFIKKDQPAKVKFDAYSYQDYGVVPGKVSSISSDSKYDPKLGNVYQVEVELERHHIVDNNKRI
KFRPGQSATANIVIRQRRIIDVLLDPIKQLKSGNTKK
>Mature_516_residues
GAKVLTISDQELGKKNDQRSSLNQPKIQNFVYKNNDIIDWSASLQSLLDQPPAEMPLRIISSGLVFLLAFLGWAWLGKIE
DIGTAKGKLVPKGETYKVESVAIGKVSRIAVKEGETVAAGQVIAELDTSLDKKEVKRLEQMLSSYQQELKQKQSLLNKVY
LEAQTHQRISTSENLGQESAIKSAEDRADTLLQLLIQQKQELNAYNARHKRLKLLSNLSRSRVKQLELDLKSNQGRVKKL
KSLKKQGAISSELVFQANQNLSQVQSQITESKLQDITSVSQQIFQNEQSMRTLAAKMTQDQGELYSAYRQVEQLKAELNR
NKAERTRLKLEAYQKIDQLKLETTQAKTKVSETKNQMLKAKATLDQKLFKAPIDGVVLSFNLKNEGKVVNSGQTVAEIAP
HNTPLIISAVLPNKEAGFIKKDQPAKVKFDAYSYQDYGVVPGKVSSISSDSKYDPKLGNVYQVEVELERHHIVDNNKRIK
FRPGQSATANIVIRQRRIIDVLLDPIKQLKSGNTKK

Specific function: Involved in the transport of hemolysin A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 58077; Mature: 57946

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAKVLTISDQELGKKNDQRSSLNQPKIQNFVYKNNDIIDWSASLQSLLDQPPAEMPLRI
CCCEEEEECCHHHCCCCCHHHCCCCCHHHHHEECCCCEEEHHHHHHHHHCCCCHHHHHHH
ISSGLVFLLAFLGWAWLGKIEDIGTAKGKLVPKGETYKVESVAIGKVSRIAVKEGETVAA
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEEECCCHHEEEECCCCCHHH
GQVIAELDTSLDKKEVKRLEQMLSSYQQELKQKQSLLNKVYLEAQTHQRISTSENLGQES
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHH
AIKSAEDRADTLLQLLIQQKQELNAYNARHKRLKLLSNLSRSRVKQLELDLKSNQGRVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LKSLKKQGAISSELVFQANQNLSQVQSQITESKLQDITSVSQQIFQNEQSMRTLAAKMTQ
HHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DQGELYSAYRQVEQLKAELNRNKAERTRLKLEAYQKIDQLKLETTQAKTKVSETKNQMLK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKATLDQKLFKAPIDGVVLSFNLKNEGKVVNSGQTVAEIAPHNTPLIISAVLPNKEAGFI
HHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCHHHHCCCCCCEEEEEECCCCCCCCC
KKDQPAKVKFDAYSYQDYGVVPGKVSSISSDSKYDPKLGNVYQVEVELERHHIVDNNKRI
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHCCCCCCEE
KFRPGQSATANIVIRQRRIIDVLLDPIKQLKSGNTKK
EECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GAKVLTISDQELGKKNDQRSSLNQPKIQNFVYKNNDIIDWSASLQSLLDQPPAEMPLRI
CCEEEEECCHHHCCCCCHHHCCCCCHHHHHEECCCCEEEHHHHHHHHHCCCCHHHHHHH
ISSGLVFLLAFLGWAWLGKIEDIGTAKGKLVPKGETYKVESVAIGKVSRIAVKEGETVAA
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEEECCCHHEEEECCCCCHHH
GQVIAELDTSLDKKEVKRLEQMLSSYQQELKQKQSLLNKVYLEAQTHQRISTSENLGQES
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHH
AIKSAEDRADTLLQLLIQQKQELNAYNARHKRLKLLSNLSRSRVKQLELDLKSNQGRVKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LKSLKKQGAISSELVFQANQNLSQVQSQITESKLQDITSVSQQIFQNEQSMRTLAAKMTQ
HHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DQGELYSAYRQVEQLKAELNRNKAERTRLKLEAYQKIDQLKLETTQAKTKVSETKNQMLK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKATLDQKLFKAPIDGVVLSFNLKNEGKVVNSGQTVAEIAPHNTPLIISAVLPNKEAGFI
HHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCCHHHHCCCCCCEEEEEECCCCCCCCC
KKDQPAKVKFDAYSYQDYGVVPGKVSSISSDSKYDPKLGNVYQVEVELERHHIVDNNKRI
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECHHCCCCCCEE
KFRPGQSATANIVIRQRRIIDVLLDPIKQLKSGNTKK
EECCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3891743; 1495479 [H]