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The map label for this gene is menH [H]

Identifier: 158337137

GI number: 158337137

Start: 4062638

End: 4063414

Strand: Reverse

Name: menH [H]

Synonym: AM1_4012

Alternate gene names: 158337137

Gene position: 4063414-4062638 (Counterclockwise)

Preceding gene: 158337144

Following gene: 158337136

Centisome position: 62.48

GC content: 42.6

Gene sequence:

>777_bases
ATGTCACCAAAATCTATTGTGCCGTCTGATGTTGGGTTATGGATGATTCATGGCAATCTCCAAACCCCTAAAGTATGGCA
CCCCATCACAACGCAACTTCATCAAGCGGTCAGGCCCAAGCTCAACCTATCCATTTTCTTGGAAGATCTATGGACCAGTC
CAGGAGACTCTTTAGAGGAATGGGCAGCTCTATTTTGTCAACGCGTTCACACCCATCACTTTAAGTCTCGTTTCTTACTG
GGTTATTCCTTGGGCGGTCGGTTAGCTTTTCATGCGCTGCTACATCGACCTGAATTATGGCAAGGAGCGATCATTATCAG
TGCTGACTCGGGGTTGGAATCAGAGTGCGATCGCAACCGCTGTCTCCAAAGAGATAAAGCTTGGAGCAACAAATTTCTGC
ATGATAAGTGGGAAAACCTGATGCAGGAGTGGAATTCACTCTCCGTATTCTGTGGACGCCAGCCTACCTATTCAGTCTTA
GAAAAAGATTTTTCTCGCATTAAACTCTCACAGATATTTCAGATCTTCTCCAAGGGACACCAAAGCAATCTCCTCCCAAA
TTTACAAACTCTCAACGCACCAATTTTGTATATATCAGGGTCAGAAGACATGCATTATTGCCAAATTGGCCAAAAGCTAG
ATCGTCATTGTTTATCAATCAATCATCGCATTATTTTAAATGCTGGGCATCGTGTTCCCTGGGAGAAAAAAAATTCATTC
TTACTAGTCTTAACTCATTTTTTAACCAGAGGTTATAATACTCAAAAAGCAAACTGA

Upstream 100 bases:

>100_bases
GTGCAGTGTAGACATTGAATCGAGCATCTATCCTAGGGCCAGCCTGTGCGTCTTGACAGCGCCCCTTCTATTAGCTAAGT
GAAATCATATACTGAGCATC

Downstream 100 bases:

>100_bases
GACAGGATTACATAATTCCATTATCCAGATTTATTTACTGAAGCAAGCATCAAGCGAATAAAGTTTATAGCCAACAGAGC
CAAGCAATATTTTAAGTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: SHCHC synthase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSPKSIVPSDVGLWMIHGNLQTPKVWHPITTQLHQAVRPKLNLSIFLEDLWTSPGDSLEEWAALFCQRVHTHHFKSRFLL
GYSLGGRLAFHALLHRPELWQGAIIISADSGLESECDRNRCLQRDKAWSNKFLHDKWENLMQEWNSLSVFCGRQPTYSVL
EKDFSRIKLSQIFQIFSKGHQSNLLPNLQTLNAPILYISGSEDMHYCQIGQKLDRHCLSINHRIILNAGHRVPWEKKNSF
LLVLTHFLTRGYNTQKAN

Sequences:

>Translated_258_residues
MSPKSIVPSDVGLWMIHGNLQTPKVWHPITTQLHQAVRPKLNLSIFLEDLWTSPGDSLEEWAALFCQRVHTHHFKSRFLL
GYSLGGRLAFHALLHRPELWQGAIIISADSGLESECDRNRCLQRDKAWSNKFLHDKWENLMQEWNSLSVFCGRQPTYSVL
EKDFSRIKLSQIFQIFSKGHQSNLLPNLQTLNAPILYISGSEDMHYCQIGQKLDRHCLSINHRIILNAGHRVPWEKKNSF
LLVLTHFLTRGYNTQKAN
>Mature_257_residues
SPKSIVPSDVGLWMIHGNLQTPKVWHPITTQLHQAVRPKLNLSIFLEDLWTSPGDSLEEWAALFCQRVHTHHFKSRFLLG
YSLGGRLAFHALLHRPELWQGAIIISADSGLESECDRNRCLQRDKAWSNKFLHDKWENLMQEWNSLSVFCGRQPTYSVLE
KDFSRIKLSQIFQIFSKGHQSNLLPNLQTLNAPILYISGSEDMHYCQIGQKLDRHCLSINHRIILNAGHRVPWEKKNSFL
LVLTHFLTRGYNTQKAN

Specific function: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. MenH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =4.2.99.20 [H]

Molecular weight: Translated: 29875; Mature: 29743

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPKSIVPSDVGLWMIHGNLQTPKVWHPITTQLHQAVRPKLNLSIFLEDLWTSPGDSLEE
CCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCHHH
WAALFCQRVHTHHFKSRFLLGYSLGGRLAFHALLHRPELWQGAIIISADSGLESECDRNR
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
CLQRDKAWSNKFLHDKWENLMQEWNSLSVFCGRQPTYSVLEKDFSRIKLSQIFQIFSKGH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QSNLLPNLQTLNAPILYISGSEDMHYCQIGQKLDRHCLSINHRIILNAGHRVPWEKKNSF
CCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCE
LLVLTHFLTRGYNTQKAN
EHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SPKSIVPSDVGLWMIHGNLQTPKVWHPITTQLHQAVRPKLNLSIFLEDLWTSPGDSLEE
CCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCHHH
WAALFCQRVHTHHFKSRFLLGYSLGGRLAFHALLHRPELWQGAIIISADSGLESECDRNR
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
CLQRDKAWSNKFLHDKWENLMQEWNSLSVFCGRQPTYSVLEKDFSRIKLSQIFQIFSKGH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QSNLLPNLQTLNAPILYISGSEDMHYCQIGQKLDRHCLSINHRIILNAGHRVPWEKKNSF
CCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCE
LLVLTHFLTRGYNTQKAN
EHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA