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The map label for this gene is hetI [H]

Identifier: 158337053

GI number: 158337053

Start: 3978038

End: 3978778

Strand: Reverse

Name: hetI [H]

Synonym: AM1_3926

Alternate gene names: 158337053

Gene position: 3978778-3978038 (Counterclockwise)

Preceding gene: 158337058

Following gene: 158337052

Centisome position: 61.18

GC content: 47.37

Gene sequence:

>741_bases
ATGTCCGATTGTCAATGGATACCCACTCATACAGTCACCCCGATTGCCCCCCAGACACTGCATATCTGGCGACTCCCTTT
AAGAACAGACGGAGCTAGTCATTGGTGGGACTTACTCTCTAGGGATGAGCAGCAGCGAGCCCAACGGTTTGTGCGATCGC
AAGATCAGGACAAGTATGTGCAGGTCCGCGGAACTCTACGATGCTTATTGGGCCAATATTTGCAGATACCCGGTCACACC
CTGCGCTTTGATTATGGAGATTATGGCAAGCCTCAACTCGTATCGTCTTGCAATTCATTAAATCTGCAATTTAACGTTTC
TCATTCCCATGAGTTAGCGTTAATTGCCATTACTCAGGCGACGGCAGTAGGTATTGATATTGAGCAGATGAACCCACAAG
CTAGATATATAAATATCAGCCAACGTTTTTTTTCCGTAGCAGAACACGAGATTCTCTTGCAACAGCCTGTAGAACAGCAG
TGTCATACTTTTTTTCAACTGTGGACCCGGAAAGAGGCTTGTGTGAAGGCAATGGGTGGCAGCATTGCTCATGTGCTCGA
TCAAATTAATGTGGCTCAGGGATTAAATCAAACCAGTATTGCTATTGAGGTGCAGGAGGAGCCCCATCAACTCTTTCTGC
GTAACCTTATCCCAGATCCTAACTTTGCCGGAGCCGTAGCAACCCAAGCGCCCTTGCAACATCTACACCTATGGCAGTGG
GACTCTATCAGTTCAGGCTAA

Upstream 100 bases:

>100_bases
TATACATCTCTCAAACTATGTCTCTCACTTTAGCAAGGGATGTAGACGCAACCCTTGCCGGGTTGAAACCTGCGGTGAGG
AAAGTATCAAAGCGACGAAT

Downstream 100 bases:

>100_bases
TTAATTTGTCTGGAACATTAATTGGAATCACTGACAAGCAAAGGCTAAGATAAATTAAAGATATGTTACGATTTTTAATA
TAAAGAGTACAATTCAAGTC

Product: phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSDCQWIPTHTVTPIAPQTLHIWRLPLRTDGASHWWDLLSRDEQQRAQRFVRSQDQDKYVQVRGTLRCLLGQYLQIPGHT
LRFDYGDYGKPQLVSSCNSLNLQFNVSHSHELALIAITQATAVGIDIEQMNPQARYINISQRFFSVAEHEILLQQPVEQQ
CHTFFQLWTRKEACVKAMGGSIAHVLDQINVAQGLNQTSIAIEVQEEPHQLFLRNLIPDPNFAGAVATQAPLQHLHLWQW
DSISSG

Sequences:

>Translated_246_residues
MSDCQWIPTHTVTPIAPQTLHIWRLPLRTDGASHWWDLLSRDEQQRAQRFVRSQDQDKYVQVRGTLRCLLGQYLQIPGHT
LRFDYGDYGKPQLVSSCNSLNLQFNVSHSHELALIAITQATAVGIDIEQMNPQARYINISQRFFSVAEHEILLQQPVEQQ
CHTFFQLWTRKEACVKAMGGSIAHVLDQINVAQGLNQTSIAIEVQEEPHQLFLRNLIPDPNFAGAVATQAPLQHLHLWQW
DSISSG
>Mature_245_residues
SDCQWIPTHTVTPIAPQTLHIWRLPLRTDGASHWWDLLSRDEQQRAQRFVRSQDQDKYVQVRGTLRCLLGQYLQIPGHTL
RFDYGDYGKPQLVSSCNSLNLQFNVSHSHELALIAITQATAVGIDIEQMNPQARYINISQRFFSVAEHEILLQQPVEQQC
HTFFQLWTRKEACVKAMGGSIAHVLDQINVAQGLNQTSIAIEVQEEPHQLFLRNLIPDPNFAGAVATQAPLQHLHLWQWD
SISSG

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

Organism=Homo sapiens, GI20357568, Length=156, Percent_Identity=29.4871794871795, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1789886, Length=97, Percent_Identity=37.1134020618557, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 28066; Mature: 27935

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDCQWIPTHTVTPIAPQTLHIWRLPLRTDGASHWWDLLSRDEQQRAQRFVRSQDQDKYV
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEE
QVRGTLRCLLGQYLQIPGHTLRFDYGDYGKPQLVSSCNSLNLQFNVSHSHELALIAITQA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCEEEEEEECCCCCEEEEEEECH
TAVGIDIEQMNPQARYINISQRFFSVAEHEILLQQPVEQQCHTFFQLWTRKEACVKAMGG
HEEEEEHHHCCCCCEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
SIAHVLDQINVAQGLNQTSIAIEVQEEPHQLFLRNLIPDPNFAGAVATQAPLQHLHLWQW
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEECC
DSISSG
CCCCCC
>Mature Secondary Structure 
SDCQWIPTHTVTPIAPQTLHIWRLPLRTDGASHWWDLLSRDEQQRAQRFVRSQDQDKYV
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEE
QVRGTLRCLLGQYLQIPGHTLRFDYGDYGKPQLVSSCNSLNLQFNVSHSHELALIAITQA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCEEEEEEECCCCCEEEEEEECH
TAVGIDIEQMNPQARYINISQRFFSVAEHEILLQQPVEQQCHTFFQLWTRKEACVKAMGG
HEEEEEHHHCCCCCEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
SIAHVLDQINVAQGLNQTSIAIEVQEEPHQLFLRNLIPDPNFAGAVATQAPLQHLHLWQW
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEECC
DSISSG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]