Click here to switch to the map view.

The map label for this gene is lhr [C]

Identifier: 158336995

GI number: 158336995

Start: 3918204

End: 3920405

Strand: Reverse

Name: lhr [C]

Synonym: AM1_3868

Alternate gene names: 158336995

Gene position: 3920405-3918204 (Counterclockwise)

Preceding gene: 158336996

Following gene: 158336994

Centisome position: 60.28

GC content: 52.59

Gene sequence:

>2202_bases
GTGACCGCTCCTGCCACCTCCAACTTTTATCGCCTCCACCCCCGCGTTCAACAGTGGATTGCCAGCAAAAAATGGCCCTC
CCTGCGAGAAATCCAGGAGTTAGCTATCCCCCCTATCTTGGCCGGGGATAAGGATGTGATTATTACTGCAGCCACGGCCC
AAGGCAAAACCGAAGCGGCTTTTCTGCCCGTATTTTCACAACTGGTCGATCAGCCTGCCAAAGGCATTCAGGTGATTGGA
CTGGGGCCGCTTAAAGCCTTGATCAATGATCAGCATCGTCGTCTATCGGCCATTGGCGATTGCCTGGATGTGCCCGTATG
TCCCTGGCATGGGGATATTGGCTCTGGTCCCAAGCAACGCCTGCTCAAACAGCCTGCTGGTGTGCTGCTGATTACCCCGG
AGTCATTGGAAGCCCTGTTTGTTCTCCGGGGGCAAGAGCTGAATCGCTTATTTGCCTCCCTCTCCTACATTGTGATTGAT
GAAATGCATTCCTTTATCAGCATTGAGCGGGGCCGCCAGCTCCAATCCCTGATGCAGCGAGTTGAACAAGTGGTGGGGCG
TCCGGTTCCTCGGATTGGCTTGAGTGCCACTTTGGGGGATATGTCCTTAGCCGCAGAATTCCTCCGCCCAGGACAGCAAG
AACGGGTCCAGCTCGTCCAGTCCTTTGCCAAAGGCGATGAATTGAAGCTACAGCTCCGAGGCTATCGATCATCGCCAACC
CCAGACCCGGATGAAGAGGAAGACGAAACCACGCCACCCCCAGATGCCTTGGACATTGCTCAGCACCTTTTCCAATCCCT
GCGTGGGGAAAAGAATCTGATTTTTATCAACAGTCGCCGCCAGGTGGAGCGCTATGCCGATATTTTGCGCAATCTCTCAG
CAGAATACCGGGTGCCCAATGAGTTTATGCCCCATCATGGCAGCCTTTCCAAGGAGCTGCGGGCCGAGGCGGAAGAAGCC
CTTAAGCGAGATCATCCTGTCAACGTGATTTGCACCATGACCTTAGAAATGGGGATTGATGTGGGCGCTGTCCAGTCCAT
TGCTCAGATTGGCCCCCCTAGCTCCGTGGCCAGTACTCGCCAACGATTAGGACGCTCTGGCCGACGGGCAGGCGATCCAG
CCATTATGCGGGTCTATGTATCGGTGCCCCAATTAGATTCCTACACTTCCCCAGAGCAAGCGTTATATCCCGATTTAGTG
CAAGCCATCGCCATTATCAATTTGCTGCTAGAGGGCTGGTATGAACCGCCGATTGCTGGACGTCTGCATATTTCCACTCT
GATTCAACAGTTGCTATCCAGCATTGCCCAACAGGGCGGTATTCGGGCCGATCAGGCTTGGCATGACTTCTGCGAGGCAG
GTCCCTTCCAAGAAATGGAGCAAGGACTGTTTATCAAGCTTTTGCGATGCTTAGGAGAGCGCGATCTAATCCAGCAAAGC
CAGGATGGCCTGTTACTGTTGGGTCTGAAAGGCGAGCGATTGGTCAATCACTACACGTTTTACACAGCTTTTTCCACAAC
CGAAGAGTACCGAATCAGCACACCAGAGAATGTGTTGGGTACCTTACCCACTTCCATGCCCATTGCCGAGGAGATGGTGT
TGCTGTTTGCAGGCCGACGCTGGCAAGTCCAGTCTGTAGATAGTGAAAAACAGGTGGTGATGGTAGTCCCCGCAGATGGG
GAAGGACAAGCGCCCCGTTTTGGAGGCAGCAGTGGTTTTGTTCATGATCGCGTGCGGCAAACTATGCGCGAGATTTACCG
TTCCACGGATATGCCCGTTTACCTGGATGACACGGCTAAAACACTCTTAAAGGAAGCAAGAACTCAATTTCGCGATTGTG
GTTTAGATCAAGAATATATCGTTGGTGAAGATGAGCAGGTCTTGCTCTTTCCCTGGCGAGGCAGCTTGGTGATGAATACC
CTACAAATGTTGCTGTTAGATAGTGGCTTGAAGGCGAGCCAAGAGGGGCTAGCCATTAAGGTCAAGGGGGTGGAACCGGA
TGAGCTGATGCCCTATTTTCAGTCTTTGGTGAATCTAGGTCCTGCTAACCCGCTACGTTTAGCCGATGTAGTGCGAACGA
AACGCAGTGAAAAATATGACTGGGTGTTGACGGACGAGTTATTGAACCATAACTACGTAGCTCGCTTTTTCGATCCCCAA
GGCACTTGGGAAACGGTTTCAGAAATCTGTAGTGGAGGTTAG

Upstream 100 bases:

>100_bases
GATTCATTTTGAGACCGAAGTTGGCAAAGGCACCACCTTTATTTTCACCCTGCCAGCGATGGACTAAGCTCTTAGCAATG
TTCATTGCCGAGGCTGCAAC

Downstream 100 bases:

>100_bases
GTTAGATCAGTCGGCATCCGGTTCACCATAACCAACAATGGTAGATATCAATCATTGGGATACTCTATTTCAGTGCATTC
AGCAGCATGACCTATTGGGT

Product: DEAD/DEAH box RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 732

Protein sequence:

>733_residues
MTAPATSNFYRLHPRVQQWIASKKWPSLREIQELAIPPILAGDKDVIITAATAQGKTEAAFLPVFSQLVDQPAKGIQVIG
LGPLKALINDQHRRLSAIGDCLDVPVCPWHGDIGSGPKQRLLKQPAGVLLITPESLEALFVLRGQELNRLFASLSYIVID
EMHSFISIERGRQLQSLMQRVEQVVGRPVPRIGLSATLGDMSLAAEFLRPGQQERVQLVQSFAKGDELKLQLRGYRSSPT
PDPDEEEDETTPPPDALDIAQHLFQSLRGEKNLIFINSRRQVERYADILRNLSAEYRVPNEFMPHHGSLSKELRAEAEEA
LKRDHPVNVICTMTLEMGIDVGAVQSIAQIGPPSSVASTRQRLGRSGRRAGDPAIMRVYVSVPQLDSYTSPEQALYPDLV
QAIAIINLLLEGWYEPPIAGRLHISTLIQQLLSSIAQQGGIRADQAWHDFCEAGPFQEMEQGLFIKLLRCLGERDLIQQS
QDGLLLLGLKGERLVNHYTFYTAFSTTEEYRISTPENVLGTLPTSMPIAEEMVLLFAGRRWQVQSVDSEKQVVMVVPADG
EGQAPRFGGSSGFVHDRVRQTMREIYRSTDMPVYLDDTAKTLLKEARTQFRDCGLDQEYIVGEDEQVLLFPWRGSLVMNT
LQMLLLDSGLKASQEGLAIKVKGVEPDELMPYFQSLVNLGPANPLRLADVVRTKRSEKYDWVLTDELLNHNYVARFFDPQ
GTWETVSEICSGG

Sequences:

>Translated_733_residues
MTAPATSNFYRLHPRVQQWIASKKWPSLREIQELAIPPILAGDKDVIITAATAQGKTEAAFLPVFSQLVDQPAKGIQVIG
LGPLKALINDQHRRLSAIGDCLDVPVCPWHGDIGSGPKQRLLKQPAGVLLITPESLEALFVLRGQELNRLFASLSYIVID
EMHSFISIERGRQLQSLMQRVEQVVGRPVPRIGLSATLGDMSLAAEFLRPGQQERVQLVQSFAKGDELKLQLRGYRSSPT
PDPDEEEDETTPPPDALDIAQHLFQSLRGEKNLIFINSRRQVERYADILRNLSAEYRVPNEFMPHHGSLSKELRAEAEEA
LKRDHPVNVICTMTLEMGIDVGAVQSIAQIGPPSSVASTRQRLGRSGRRAGDPAIMRVYVSVPQLDSYTSPEQALYPDLV
QAIAIINLLLEGWYEPPIAGRLHISTLIQQLLSSIAQQGGIRADQAWHDFCEAGPFQEMEQGLFIKLLRCLGERDLIQQS
QDGLLLLGLKGERLVNHYTFYTAFSTTEEYRISTPENVLGTLPTSMPIAEEMVLLFAGRRWQVQSVDSEKQVVMVVPADG
EGQAPRFGGSSGFVHDRVRQTMREIYRSTDMPVYLDDTAKTLLKEARTQFRDCGLDQEYIVGEDEQVLLFPWRGSLVMNT
LQMLLLDSGLKASQEGLAIKVKGVEPDELMPYFQSLVNLGPANPLRLADVVRTKRSEKYDWVLTDELLNHNYVARFFDPQ
GTWETVSEICSGG
>Mature_732_residues
TAPATSNFYRLHPRVQQWIASKKWPSLREIQELAIPPILAGDKDVIITAATAQGKTEAAFLPVFSQLVDQPAKGIQVIGL
GPLKALINDQHRRLSAIGDCLDVPVCPWHGDIGSGPKQRLLKQPAGVLLITPESLEALFVLRGQELNRLFASLSYIVIDE
MHSFISIERGRQLQSLMQRVEQVVGRPVPRIGLSATLGDMSLAAEFLRPGQQERVQLVQSFAKGDELKLQLRGYRSSPTP
DPDEEEDETTPPPDALDIAQHLFQSLRGEKNLIFINSRRQVERYADILRNLSAEYRVPNEFMPHHGSLSKELRAEAEEAL
KRDHPVNVICTMTLEMGIDVGAVQSIAQIGPPSSVASTRQRLGRSGRRAGDPAIMRVYVSVPQLDSYTSPEQALYPDLVQ
AIAIINLLLEGWYEPPIAGRLHISTLIQQLLSSIAQQGGIRADQAWHDFCEAGPFQEMEQGLFIKLLRCLGERDLIQQSQ
DGLLLLGLKGERLVNHYTFYTAFSTTEEYRISTPENVLGTLPTSMPIAEEMVLLFAGRRWQVQSVDSEKQVVMVVPADGE
GQAPRFGGSSGFVHDRVRQTMREIYRSTDMPVYLDDTAKTLLKEARTQFRDCGLDQEYIVGEDEQVLLFPWRGSLVMNTL
QMLLLDSGLKASQEGLAIKVKGVEPDELMPYFQSLVNLGPANPLRLADVVRTKRSEKYDWVLTDELLNHNYVARFFDPQG
TWETVSEICSGG

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=517, Percent_Identity=25.7253384912959, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321020, Length=412, Percent_Identity=24.2718446601942, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 81848; Mature: 81717

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPATSNFYRLHPRVQQWIASKKWPSLREIQELAIPPILAGDKDVIITAATAQGKTEAA
CCCCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCEEEEEECCCCCCCHH
FLPVFSQLVDQPAKGIQVIGLGPLKALINDQHRRLSAIGDCLDVPVCPWHGDIGSGPKQR
HHHHHHHHHCCCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
LLKQPAGVLLITPESLEALFVLRGQELNRLFASLSYIVIDEMHSFISIERGRQLQSLMQR
HHHCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VEQVVGRPVPRIGLSATLGDMSLAAEFLRPGQQERVQLVQSFAKGDELKLQLRGYRSSPT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
PDPDEEEDETTPPPDALDIAQHLFQSLRGEKNLIFINSRRQVERYADILRNLSAEYRVPN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCH
EFMPHHGSLSKELRAEAEEALKRDHPVNVICTMTLEMGIDVGAVQSIAQIGPPSSVASTR
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCHHHHHHHHHCCCCHHHHHHH
QRLGRSGRRAGDPAIMRVYVSVPQLDSYTSPEQALYPDLVQAIAIINLLLEGWYEPPIAG
HHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLHISTLIQQLLSSIAQQGGIRADQAWHDFCEAGPFQEMEQGLFIKLLRCLGERDLIQQS
EEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHCC
QDGLLLLGLKGERLVNHYTFYTAFSTTEEYRISTPENVLGTLPTSMPIAEEMVLLFAGRR
CCCEEEEECCCCHHHHHEEEEEEECCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHCCCC
WQVQSVDSEKQVVMVVPADGEGQAPRFGGSSGFVHDRVRQTMREIYRSTDMPVYLDDTAK
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHH
TLLKEARTQFRDCGLDQEYIVGEDEQVLLFPWRGSLVMNTLQMLLLDSGLKASQEGLAIK
HHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEE
VKGVEPDELMPYFQSLVNLGPANPLRLADVVRTKRSEKYDWVLTDELLNHNYVARFFDPQ
EECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHCCCCEEEEECCC
GTWETVSEICSGG
CCHHHHHHHHCCC
>Mature Secondary Structure 
TAPATSNFYRLHPRVQQWIASKKWPSLREIQELAIPPILAGDKDVIITAATAQGKTEAA
CCCCCCCEEEECHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCEEEEEECCCCCCCHH
FLPVFSQLVDQPAKGIQVIGLGPLKALINDQHRRLSAIGDCLDVPVCPWHGDIGSGPKQR
HHHHHHHHHCCCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
LLKQPAGVLLITPESLEALFVLRGQELNRLFASLSYIVIDEMHSFISIERGRQLQSLMQR
HHHCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VEQVVGRPVPRIGLSATLGDMSLAAEFLRPGQQERVQLVQSFAKGDELKLQLRGYRSSPT
HHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCC
PDPDEEEDETTPPPDALDIAQHLFQSLRGEKNLIFINSRRQVERYADILRNLSAEYRVPN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCH
EFMPHHGSLSKELRAEAEEALKRDHPVNVICTMTLEMGIDVGAVQSIAQIGPPSSVASTR
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCHHHHHHHHHCCCCHHHHHHH
QRLGRSGRRAGDPAIMRVYVSVPQLDSYTSPEQALYPDLVQAIAIINLLLEGWYEPPIAG
HHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLHISTLIQQLLSSIAQQGGIRADQAWHDFCEAGPFQEMEQGLFIKLLRCLGERDLIQQS
EEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHCC
QDGLLLLGLKGERLVNHYTFYTAFSTTEEYRISTPENVLGTLPTSMPIAEEMVLLFAGRR
CCCEEEEECCCCHHHHHEEEEEEECCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHCCCC
WQVQSVDSEKQVVMVVPADGEGQAPRFGGSSGFVHDRVRQTMREIYRSTDMPVYLDDTAK
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHH
TLLKEARTQFRDCGLDQEYIVGEDEQVLLFPWRGSLVMNTLQMLLLDSGLKASQEGLAIK
HHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEE
VKGVEPDELMPYFQSLVNLGPANPLRLADVVRTKRSEKYDWVLTDELLNHNYVARFFDPQ
EECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEHHHHCCCCEEEEECCC
GTWETVSEICSGG
CCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]