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The map label for this gene is aphA [H]

Identifier: 158336996

GI number: 158336996

Start: 3920439

End: 3922415

Strand: Reverse

Name: aphA [H]

Synonym: AM1_3869

Alternate gene names: 158336996

Gene position: 3922415-3920439 (Counterclockwise)

Preceding gene: 158336997

Following gene: 158336995

Centisome position: 60.31

GC content: 48.25

Gene sequence:

>1977_bases
GTGGCGACTCAGCCGATTGAAGAGGGTTCCACAGATGTTGTTCAACGCCAGCTGGCTGAGATTCAACAACAGCAATCGCA
GCAGCAGCGCTTTTACAGCGCTCTACAAAGTGCGATGGAAGGAATTGCTCAACTCGACCCGCAGGGTTGTTTTATGGAGG
TTAATCGGACCTATGCCCATGATGTTGGCTATAGTCCCGAAGAATTAGTGGGGTTGCCCTGGCAAACCACCGTGTTTGCC
AACGACATTCCCATTTTGGAATCGGCTTACAACATTATGCTAGACACGGGCAAGATTTCTGTGGAAGCACGAGGAGCCAC
TAAACAAGGGGCCGTTTTCTATCAGCAGCTCACGATGGTGGCGAATCGGAACGACCAGGGCGAGTTTCTAGGGCATTTTT
GTTTTATGCAGAATATCAGCGATCGCAAACTGGCCGAAGTCAAGCGAATTGAAAGCGAACAGCGATTTCAGGCTATAGCT
GACTGTTCATCCACGCTGATCTGGGTCGCGGATCAGCGAAATCAACGGACCTATTTCAACGCAGAATGGCTGAAGTTTAC
GGGTAGGTCTTTAAAGCGAGAAATTGAAGAGGGGTGGGCAACGGGAATTCATCCTGCAGATGTTCATGACTGCCTAGCAG
CCTTTGCCTTGGCCTTTGAAGAACAGCGATCGGTTCAACTCGAATATCGGTACCTGAATCATGCGGGCCACTACCGATGG
TTACTCGATTCTGGACGACCCCGATTTTTGCCGAATGGGGAGTTTGTGGGCTATGTGGGATCTTGCATTGATATCACTCC
CTTTAAGCAGGTGGCTGACTCCCTAGAACAAGCGAACTACCAATTACAGGAAAATATCAATAAGAGTATTGATGCCTTAG
TGGGGGCAAATGCCCAATTAGAGGAAAGTGAGGCTCGATTTCGCTCCTTGGCAGACTCCTTACCTGCATTGATCTGGGTC
TGCGATACTGAACAACTCTGCACTTACGTTAATCAGACTTGGCAAACCTTTACGGGACGTTCTCTGGAGCAAGAAACCAA
TTTAGGCTGGCTGGATACCATTCATCCTGATGATCGCCCCCGGTTTATTGACCAGCTCCAGACTTGCTTTTCTGAAGAAA
TCCCTTTGCATTTAGAGTATCGACGATGCGATCGCAACGGCACGTACCGCTGGATTCTCAATACCGGTATTCCTCGATAT
ATCGCCGATCAGTTTGCGGGGATGATCGGCTGCGGCCTAGATATCACGGTGTCGAAGCAAAATCAGGTTGCCTTAGAACA
AGCTATCTCTGAATTAACGCGTTCGAACCGAGACTTAGAAGAATTTGCCTATGTTGCTTCCCATGATCTGCGAGAGCCAT
TACGCAAAATTAGAAGCTTTTCTGAATTACTGGTCGAAGATTATGCAGACCAGATTGATGACACGGGTCGCCGCTACTTT
GATTACGTGATTGATGGTGCTGCGCGAATGGATGCCTTAGTGCAATCTGTCCTGCAATATTCTCGGGTTGGTCGTCAGCA
AGAGATCCCTGAACCCGTTGATCTAAATACTGTCGTCCAACAAATCGCCAATGATTTCAGTTTAGTGATTGAACAAAAGC
AAGGCTGGATTATTTATGATGAGTTGCCGACGATCATCATCAGCAAAATCGAAAGCGTGCAGCTCTTTCAAAACCTGATT
GGCAATGCCCTCAAGTTTCATGGTGTTCAACCGCCCCATATTACGGTTAAAGCCCAACGCCAAGGCACTCATTGGCAGAT
TTCAGTCAGCGATACGGGAATTGGTATCGCGCCGGAATTTTGCGATCGCGTGTTCACCATGTTTGCCCGTCAACATCAGC
GCGATCAATATCCCGGTACAGGCATTGGTCTCTCCATTTGCCGAAAAATTGTCGAGAACTATGGGGGCCAGATTCATTTT
GAGACCGAAGTTGGCAAAGGCACCACCTTTATTTTCACCCTGCCAGCGATGGACTAA

Upstream 100 bases:

>100_bases
GCTGCCCTATCTACCGGTGGTAGACGATCAGCAGCTAGTTGGGATTTTAAGCCTGGAGCAGTTACGCATCTGGGAACTGA
CCTCAGTCCAGTCCAACGTT

Downstream 100 bases:

>100_bases
GCTCTTAGCAATGTTCATTGCCGAGGCTGCAACGTGACCGCTCCTGCCACCTCCAACTTTTATCGCCTCCACCCCCGCGT
TCAACAGTGGATTGCCAGCA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 657

Protein sequence:

>658_residues
MATQPIEEGSTDVVQRQLAEIQQQQSQQQRFYSALQSAMEGIAQLDPQGCFMEVNRTYAHDVGYSPEELVGLPWQTTVFA
NDIPILESAYNIMLDTGKISVEARGATKQGAVFYQQLTMVANRNDQGEFLGHFCFMQNISDRKLAEVKRIESEQRFQAIA
DCSSTLIWVADQRNQRTYFNAEWLKFTGRSLKREIEEGWATGIHPADVHDCLAAFALAFEEQRSVQLEYRYLNHAGHYRW
LLDSGRPRFLPNGEFVGYVGSCIDITPFKQVADSLEQANYQLQENINKSIDALVGANAQLEESEARFRSLADSLPALIWV
CDTEQLCTYVNQTWQTFTGRSLEQETNLGWLDTIHPDDRPRFIDQLQTCFSEEIPLHLEYRRCDRNGTYRWILNTGIPRY
IADQFAGMIGCGLDITVSKQNQVALEQAISELTRSNRDLEEFAYVASHDLREPLRKIRSFSELLVEDYADQIDDTGRRYF
DYVIDGAARMDALVQSVLQYSRVGRQQEIPEPVDLNTVVQQIANDFSLVIEQKQGWIIYDELPTIIISKIESVQLFQNLI
GNALKFHGVQPPHITVKAQRQGTHWQISVSDTGIGIAPEFCDRVFTMFARQHQRDQYPGTGIGLSICRKIVENYGGQIHF
ETEVGKGTTFIFTLPAMD

Sequences:

>Translated_658_residues
MATQPIEEGSTDVVQRQLAEIQQQQSQQQRFYSALQSAMEGIAQLDPQGCFMEVNRTYAHDVGYSPEELVGLPWQTTVFA
NDIPILESAYNIMLDTGKISVEARGATKQGAVFYQQLTMVANRNDQGEFLGHFCFMQNISDRKLAEVKRIESEQRFQAIA
DCSSTLIWVADQRNQRTYFNAEWLKFTGRSLKREIEEGWATGIHPADVHDCLAAFALAFEEQRSVQLEYRYLNHAGHYRW
LLDSGRPRFLPNGEFVGYVGSCIDITPFKQVADSLEQANYQLQENINKSIDALVGANAQLEESEARFRSLADSLPALIWV
CDTEQLCTYVNQTWQTFTGRSLEQETNLGWLDTIHPDDRPRFIDQLQTCFSEEIPLHLEYRRCDRNGTYRWILNTGIPRY
IADQFAGMIGCGLDITVSKQNQVALEQAISELTRSNRDLEEFAYVASHDLREPLRKIRSFSELLVEDYADQIDDTGRRYF
DYVIDGAARMDALVQSVLQYSRVGRQQEIPEPVDLNTVVQQIANDFSLVIEQKQGWIIYDELPTIIISKIESVQLFQNLI
GNALKFHGVQPPHITVKAQRQGTHWQISVSDTGIGIAPEFCDRVFTMFARQHQRDQYPGTGIGLSICRKIVENYGGQIHF
ETEVGKGTTFIFTLPAMD
>Mature_657_residues
ATQPIEEGSTDVVQRQLAEIQQQQSQQQRFYSALQSAMEGIAQLDPQGCFMEVNRTYAHDVGYSPEELVGLPWQTTVFAN
DIPILESAYNIMLDTGKISVEARGATKQGAVFYQQLTMVANRNDQGEFLGHFCFMQNISDRKLAEVKRIESEQRFQAIAD
CSSTLIWVADQRNQRTYFNAEWLKFTGRSLKREIEEGWATGIHPADVHDCLAAFALAFEEQRSVQLEYRYLNHAGHYRWL
LDSGRPRFLPNGEFVGYVGSCIDITPFKQVADSLEQANYQLQENINKSIDALVGANAQLEESEARFRSLADSLPALIWVC
DTEQLCTYVNQTWQTFTGRSLEQETNLGWLDTIHPDDRPRFIDQLQTCFSEEIPLHLEYRRCDRNGTYRWILNTGIPRYI
ADQFAGMIGCGLDITVSKQNQVALEQAISELTRSNRDLEEFAYVASHDLREPLRKIRSFSELLVEDYADQIDDTGRRYFD
YVIDGAARMDALVQSVLQYSRVGRQQEIPEPVDLNTVVQQIANDFSLVIEQKQGWIIYDELPTIIISKIESVQLFQNLIG
NALKFHGVQPPHITVKAQRQGTHWQISVSDTGIGIAPEFCDRVFTMFARQHQRDQYPGTGIGLSICRKIVENYGGQIHFE
TEVGKGTTFIFTLPAMD

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=397, Percent_Identity=27.2040302267003, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=25.9052924791086, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=26.171875, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=26.171875, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=29.1479820627803, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=29.045643153527, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786912, Length=211, Percent_Identity=28.9099526066351, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=23.8493723849372, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=220, Percent_Identity=24.5454545454545, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=25.9398496240602, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=28.4444444444444, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75050; Mature: 74919

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQPIEEGSTDVVQRQLAEIQQQQSQQQRFYSALQSAMEGIAQLDPQGCFMEVNRTYAH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHH
DVGYSPEELVGLPWQTTVFANDIPILESAYNIMLDTGKISVEARGATKQGAVFYQQLTMV
CCCCCHHHHCCCCCEEEEEECCCCHHHHHHHEEEECCEEEEEECCCCCCCHHHHHHHHHH
ANRNDQGEFLGHFCFMQNISDRKLAEVKRIESEQRFQAIADCSSTLIWVADQRNQRTYFN
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEC
AEWLKFTGRSLKREIEEGWATGIHPADVHDCLAAFALAFEEQRSVQLEYRYLNHAGHYRW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEE
LLDSGRPRFLPNGEFVGYVGSCIDITPFKQVADSLEQANYQLQENINKSIDALVGANAQL
EEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
EESEARFRSLADSLPALIWVCDTEQLCTYVNQTWQTFTGRSLEQETNLGWLDTIHPDDRP
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCCCCH
RFIDQLQTCFSEEIPLHLEYRRCDRNGTYRWILNTGIPRYIADQFAGMIGCGLDITVSKQ
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCC
NQVALEQAISELTRSNRDLEEFAYVASHDLREPLRKIRSFSELLVEDYADQIDDTGRRYF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYVIDGAARMDALVQSVLQYSRVGRQQEIPEPVDLNTVVQQIANDFSLVIEQKQGWIIYD
HHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEC
ELPTIIISKIESVQLFQNLIGNALKFHGVQPPHITVKAQRQGTHWQISVSDTGIGIAPEF
CHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHH
CDRVFTMFARQHQRDQYPGTGIGLSICRKIVENYGGQIHFETEVGKGTTFIFTLPAMD
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCC
>Mature Secondary Structure 
ATQPIEEGSTDVVQRQLAEIQQQQSQQQRFYSALQSAMEGIAQLDPQGCFMEVNRTYAH
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHH
DVGYSPEELVGLPWQTTVFANDIPILESAYNIMLDTGKISVEARGATKQGAVFYQQLTMV
CCCCCHHHHCCCCCEEEEEECCCCHHHHHHHEEEECCEEEEEECCCCCCCHHHHHHHHHH
ANRNDQGEFLGHFCFMQNISDRKLAEVKRIESEQRFQAIADCSSTLIWVADQRNQRTYFN
HCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEC
AEWLKFTGRSLKREIEEGWATGIHPADVHDCLAAFALAFEEQRSVQLEYRYLNHAGHYRW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEE
LLDSGRPRFLPNGEFVGYVGSCIDITPFKQVADSLEQANYQLQENINKSIDALVGANAQL
EEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
EESEARFRSLADSLPALIWVCDTEQLCTYVNQTWQTFTGRSLEQETNLGWLDTIHPDDRP
HHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHCCCCEEECCCCCCCH
RFIDQLQTCFSEEIPLHLEYRRCDRNGTYRWILNTGIPRYIADQFAGMIGCGLDITVSKQ
HHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCC
NQVALEQAISELTRSNRDLEEFAYVASHDLREPLRKIRSFSELLVEDYADQIDDTGRRYF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYVIDGAARMDALVQSVLQYSRVGRQQEIPEPVDLNTVVQQIANDFSLVIEQKQGWIIYD
HHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEECCCCEEEEC
ELPTIIISKIESVQLFQNLIGNALKFHGVQPPHITVKAQRQGTHWQISVSDTGIGIAPEF
CHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHH
CDRVFTMFARQHQRDQYPGTGIGLSICRKIVENYGGQIHFETEVGKGTTFIFTLPAMD
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]