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The map label for this gene is cvrA [H]

Identifier: 158336967

GI number: 158336967

Start: 3892860

End: 3894725

Strand: Reverse

Name: cvrA [H]

Synonym: AM1_3840

Alternate gene names: 158336967

Gene position: 3894725-3892860 (Counterclockwise)

Preceding gene: 158336968

Following gene: 158336965

Centisome position: 59.88

GC content: 50.96

Gene sequence:

>1866_bases
ATGGAAGGAAATTTAGAAATTACCCTGTTAATGGTGATCACTGTTGTGGCAGGGATTTCAGCCCAGGTGATTGCTGATTT
TCTCAAAGTTCCCAGTATTGTTTTTCTGCTGCTGTTTGGCATTGCCATGGGGCCGAGTGGTTTTGGGGTGCTCCACCCCA
GCTTGCTGGGGAATGGTTTAGAGGTGATGGTCTCTCTCTGTGTGGCGCTTATCCTGTTTGAAGGGGGGCTGAACTTACAG
CTGAGGGAGGTGGAAGAAGTTTCCACTAGCTTGCGCAATTTGGTGACGGTGGGAGCGTTGGTCACTTTGTTCGGCGGGGG
TCTCGCAGCCCACTGGTTGAGCGAGTTCCCTTGGCAAATTGCTTTTCTCTATGCCTCTCTGGTGGTAGTGACGGGGCCAA
CGGTGGTGGCTCCCCTGCTGAAACAGGTGAATGCCGACCGACAGGTGTCGACCCTTTTAGAAGGGGAAGGCGTCCTGATT
GATCCAGTTGGGGCAATTTTAGCGGTTGTCGTCCTCAATATTGTCCTGCAAGGGAATGCTGATCCGTTCACTATTGTCAG
TGGTCTGCTGTTGCGTCTGGGGATTGGAGGCGTTATTGGGATTGGGGGCGGCTGGCTGTTGGGCCTGTTTCTCAAACGAG
CCCGATTTCTCTCGGAAGACTTGAAAAATTTATCGGTTTTAGCGGGGCTGTGGGGGTTATTTGGCCTCTCCCAAGCCTTG
ATTAGCGAATCAGGATTGATGACAGCGGTAGCGGCGGGCATCATGCTTAAAATTGCCGCGTTGCCAGAAGAGCGACTGCT
GCTGCGGTTTAAGAATCAACTGAGCATTCTGGCGATTTCAGTTTTATTTATTCTGCTGTCTGCCGATTTGTCCATTGCCA
GTATTTTTGCGTTGGGTTGGGGAGGAACATTTACGGTTGCAGCGTTAATGCTGATTGTGCGCCCTCTGAATGTCCTGGTA
TCGACCTGGTCCAGTGACCTGAATTGGCGGCAAAAGGCATTTTTATCTTGGGTGGCCCCTCGGGGAATTGTAGCGGCATC
GGTGGCCTCCTTATTTGCGATTTCCCTGACCAAGCAAGGAATCAATGGCGGTGATGCCATTAAAGCCCTCGTCTTTTTAA
CCATTATTTTGACGGTTTGTGTGCAGGGACTCTCTGCCCGATGGGTGGCTGGCTGGCTCAAGGTCCGCTCGGATGAGGCG
AGAGGGGCTATGATTGTGGGCTGCAATCCGTTTGGTCGAACGGTTGCCCATCTGATCAAGAGTCGGGGCGAAGATGTGGT
GATGATTGATGCCAATCCTGAATACTGCAAGCAGGCGAAAGCCGAGAATCTGACGGTGTATCGAACCAGTGCCCTGAATA
TGGATGCTCTGGATAATCTGGGTCTGGCTTCCATCGGCACCTTTTTAACAGCCACCAGTAATTCTGAGGTCAACTCGGTA
CTGGCTCAGCGGGTAATGGAAGAATTTCGACCCCCGCGAGTATTAGCGGTCTATCCCGATCAGTCGCCAGAAACGGAAGT
GGCTGAACCGGCGGAAAAATTGGCAAGCCCAGAGGTAAAGCGGGCGTTTTCTTCTCAGCTGTCCATTAAAGAATGGAATC
AGTACCTCAGCACGAATGAGGTCAAAATTACCGATACGGTCTTGGATATCGATGAGCATAAATTTAAACGGCAGCGAGAT
CATCTGCAGGCTTTGATTAATGCTGGAACCGTTATTCCGCTGCTCGTTCAGCGCCAAGACCAATTGCGTATTGCGAAGGC
GGATGAAGAGTGGCAACCTTGCGATCGCATCACCTATGGTCTTCATATCCCTAAACCTAAATTTGGACTTGCTATCCCTA
ACGAAACCATGCAGGTTTCTTCATAA

Upstream 100 bases:

>100_bases
GACGGGGAATAGGAGAGCTATGGGTTTTGCTAAGATTAGTAAGCTCAACATAAATTCACCACCCTGGATAATGGCTCAAC
GGGCCTCAAGACGATAGGAC

Downstream 100 bases:

>100_bases
GGTATCTTGGTTGTTCTGATAGCTCTGTGTACCGAGAGCGGGTCTGTTGTTCTTGAAGCCTCAAGATTTGGCTAAGTCGC
TACAGGTAGAAATGGCACTG

Product: sodium/hydrogen exchanger family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MEGNLEITLLMVITVVAGISAQVIADFLKVPSIVFLLLFGIAMGPSGFGVLHPSLLGNGLEVMVSLCVALILFEGGLNLQ
LREVEEVSTSLRNLVTVGALVTLFGGGLAAHWLSEFPWQIAFLYASLVVVTGPTVVAPLLKQVNADRQVSTLLEGEGVLI
DPVGAILAVVVLNIVLQGNADPFTIVSGLLLRLGIGGVIGIGGGWLLGLFLKRARFLSEDLKNLSVLAGLWGLFGLSQAL
ISESGLMTAVAAGIMLKIAALPEERLLLRFKNQLSILAISVLFILLSADLSIASIFALGWGGTFTVAALMLIVRPLNVLV
STWSSDLNWRQKAFLSWVAPRGIVAASVASLFAISLTKQGINGGDAIKALVFLTIILTVCVQGLSARWVAGWLKVRSDEA
RGAMIVGCNPFGRTVAHLIKSRGEDVVMIDANPEYCKQAKAENLTVYRTSALNMDALDNLGLASIGTFLTATSNSEVNSV
LAQRVMEEFRPPRVLAVYPDQSPETEVAEPAEKLASPEVKRAFSSQLSIKEWNQYLSTNEVKITDTVLDIDEHKFKRQRD
HLQALINAGTVIPLLVQRQDQLRIAKADEEWQPCDRITYGLHIPKPKFGLAIPNETMQVSS

Sequences:

>Translated_621_residues
MEGNLEITLLMVITVVAGISAQVIADFLKVPSIVFLLLFGIAMGPSGFGVLHPSLLGNGLEVMVSLCVALILFEGGLNLQ
LREVEEVSTSLRNLVTVGALVTLFGGGLAAHWLSEFPWQIAFLYASLVVVTGPTVVAPLLKQVNADRQVSTLLEGEGVLI
DPVGAILAVVVLNIVLQGNADPFTIVSGLLLRLGIGGVIGIGGGWLLGLFLKRARFLSEDLKNLSVLAGLWGLFGLSQAL
ISESGLMTAVAAGIMLKIAALPEERLLLRFKNQLSILAISVLFILLSADLSIASIFALGWGGTFTVAALMLIVRPLNVLV
STWSSDLNWRQKAFLSWVAPRGIVAASVASLFAISLTKQGINGGDAIKALVFLTIILTVCVQGLSARWVAGWLKVRSDEA
RGAMIVGCNPFGRTVAHLIKSRGEDVVMIDANPEYCKQAKAENLTVYRTSALNMDALDNLGLASIGTFLTATSNSEVNSV
LAQRVMEEFRPPRVLAVYPDQSPETEVAEPAEKLASPEVKRAFSSQLSIKEWNQYLSTNEVKITDTVLDIDEHKFKRQRD
HLQALINAGTVIPLLVQRQDQLRIAKADEEWQPCDRITYGLHIPKPKFGLAIPNETMQVSS
>Mature_621_residues
MEGNLEITLLMVITVVAGISAQVIADFLKVPSIVFLLLFGIAMGPSGFGVLHPSLLGNGLEVMVSLCVALILFEGGLNLQ
LREVEEVSTSLRNLVTVGALVTLFGGGLAAHWLSEFPWQIAFLYASLVVVTGPTVVAPLLKQVNADRQVSTLLEGEGVLI
DPVGAILAVVVLNIVLQGNADPFTIVSGLLLRLGIGGVIGIGGGWLLGLFLKRARFLSEDLKNLSVLAGLWGLFGLSQAL
ISESGLMTAVAAGIMLKIAALPEERLLLRFKNQLSILAISVLFILLSADLSIASIFALGWGGTFTVAALMLIVRPLNVLV
STWSSDLNWRQKAFLSWVAPRGIVAASVASLFAISLTKQGINGGDAIKALVFLTIILTVCVQGLSARWVAGWLKVRSDEA
RGAMIVGCNPFGRTVAHLIKSRGEDVVMIDANPEYCKQAKAENLTVYRTSALNMDALDNLGLASIGTFLTATSNSEVNSV
LAQRVMEEFRPPRVLAVYPDQSPETEVAEPAEKLASPEVKRAFSSQLSIKEWNQYLSTNEVKITDTVLDIDEHKFKRQRD
HLQALINAGTVIPLLVQRQDQLRIAKADEEWQPCDRITYGLHIPKPKFGLAIPNETMQVSS

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018421
- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 66856; Mature: 66856

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNLEITLLMVITVVAGISAQVIADFLKVPSIVFLLLFGIAMGPSGFGVLHPSLLGNGL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHCCHH
EVMVSLCVALILFEGGLNLQLREVEEVSTSLRNLVTVGALVTLFGGGLAAHWLSEFPWQI
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
AFLYASLVVVTGPTVVAPLLKQVNADRQVSTLLEGEGVLIDPVGAILAVVVLNIVLQGNA
HHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
DPFTIVSGLLLRLGIGGVIGIGGGWLLGLFLKRARFLSEDLKNLSVLAGLWGLFGLSQAL
CHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISESGLMTAVAAGIMLKIAALPEERLLLRFKNQLSILAISVLFILLSADLSIASIFALGW
HHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGTFTVAALMLIVRPLNVLVSTWSSDLNWRQKAFLSWVAPRGIVAASVASLFAISLTKQG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
INGGDAIKALVFLTIILTVCVQGLSARWVAGWLKVRSDEARGAMIVGCNPFGRTVAHLIK
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCEEEEECCHHHHHHHHHHH
SRGEDVVMIDANPEYCKQAKAENLTVYRTSALNMDALDNLGLASIGTFLTATSNSEVNSV
CCCCCEEEECCCHHHHHHCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHEECCCCHHHHH
LAQRVMEEFRPPRVLAVYPDQSPETEVAEPAEKLASPEVKRAFSSQLSIKEWNQYLSTNE
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCC
VKITDTVLDIDEHKFKRQRDHLQALINAGTVIPLLVQRQDQLRIAKADEEWQPCDRITYG
EEEEHHEECCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHEEECCCCCCCCHHHCEEC
LHIPKPKFGLAIPNETMQVSS
EECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEGNLEITLLMVITVVAGISAQVIADFLKVPSIVFLLLFGIAMGPSGFGVLHPSLLGNGL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHCCHH
EVMVSLCVALILFEGGLNLQLREVEEVSTSLRNLVTVGALVTLFGGGLAAHWLSEFPWQI
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
AFLYASLVVVTGPTVVAPLLKQVNADRQVSTLLEGEGVLIDPVGAILAVVVLNIVLQGNA
HHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCC
DPFTIVSGLLLRLGIGGVIGIGGGWLLGLFLKRARFLSEDLKNLSVLAGLWGLFGLSQAL
CHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISESGLMTAVAAGIMLKIAALPEERLLLRFKNQLSILAISVLFILLSADLSIASIFALGW
HHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGTFTVAALMLIVRPLNVLVSTWSSDLNWRQKAFLSWVAPRGIVAASVASLFAISLTKQG
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
INGGDAIKALVFLTIILTVCVQGLSARWVAGWLKVRSDEARGAMIVGCNPFGRTVAHLIK
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCEEEEECCHHHHHHHHHHH
SRGEDVVMIDANPEYCKQAKAENLTVYRTSALNMDALDNLGLASIGTFLTATSNSEVNSV
CCCCCEEEECCCHHHHHHCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHEECCCCHHHHH
LAQRVMEEFRPPRVLAVYPDQSPETEVAEPAEKLASPEVKRAFSSQLSIKEWNQYLSTNE
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCC
VKITDTVLDIDEHKFKRQRDHLQALINAGTVIPLLVQRQDQLRIAKADEEWQPCDRITYG
EEEEHHEECCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHEEECCCCCCCCHHHCEEC
LHIPKPKFGLAIPNETMQVSS
EECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA