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The map label for this gene is rsbU [H]

Identifier: 158336918

GI number: 158336918

Start: 3843301

End: 3844725

Strand: Direct

Name: rsbU [H]

Synonym: AM1_3789

Alternate gene names: 158336918

Gene position: 3843301-3844725 (Clockwise)

Preceding gene: 158336917

Following gene: 158336919

Centisome position: 59.09

GC content: 47.51

Gene sequence:

>1425_bases
ATGTCTCGAGTTCCACTTCCAAACCAACCTTCCCAATCTTTGGATTTAGACTATCCAGGGGTGGCGACAAACGTGGCAAC
TGTGACAGCGCTGCAAGAGCTTGTTTCCCATCTCCGTCGAGAACAGGCAAAAGCGCAAGATTTATTGAGTTCCCTAAGCT
TTTCGTTAAGGAGCTTTAATAATCTCAATCAGTTCCTCGCCTTAATTCCTCTAATTGTTAGCCGTGTGACCGATGCGGAT
GCTGCCGCTTTAATTTTGTTTCGTCCTAATGGACAAGTCTCTTTAGAGCAGCTTTACTGCCACGAAGGACAGCAATGTCG
AAATATTCGCTTAGCCCTAGAAAATGTGACCCGTCAGTTTACGGTTAATGGTTCTCCTGCTAAGCAACCGAACCTAGTTC
TAGAACAACAGCTGGGCCATCTTTTGGGCACAAACTATCAGTGGTTTAGTACCGCTATTTTAGTCCGAAATTTTGAACTC
CATGAGCGCGGTCGGCTGTACCTGTTTAGCAGCAATCCTGACTATGAATGGACTGAAACGCGGCAAAAGCTGGCTCAATT
AGTTGCGGATCAAACGGCGGTTGCCATTGAAAATGACACCCTGACCACCCAACTCCGTAAGCAAGAGCGGATTACCCGTG
AGCTAGAGATTGGGGCAGAGATTCAAGCTCGCTTATTACCCAACTATTCTCCCAAAATTGAAGGTGTTGCCCTAGCGGCC
ACCTGTCAAACCGCCAATCAGGTGGGGGGAGATTATTACGACTTTATTCCGATTTATCGACAGTTACCGACCTCCCGCCA
ATATCGCCTCAACCAGGCCGATCGTTGGGGGCTGGTCATTGGTGATGTCATGGGTAAAGGCGTCCCTGCTGGGCTGATTA
TGACCATGACCCGCGGTATTTTGCGGGCAGATGCGTTGCATCATCACTCTCCAGCTGAGATTTTGAAAAATCTCAATCAG
GTCATGTATGCCGATTTAGAAAATTCTAATCGGTTTGTGACGCTGTTTTATTCAGAATATGACCCTAAGACTCGTCAACT
AAGCTTTAGTAACGCGGCTCATAATCCGCCGTTGCTGTGGCGCGCTCGGGAAAATGTGATTGAGCGTTTAGATACAGACG
GTATGCTGATTGGCCTAGATGCCAATACCGAGTATCAGGAGGATAAGGTTACTCTCTCTCCAGGGGATACGATTATCTAC
TATACCGATGGCTTTACGGATGCTGCCGGTCCCAATGGTGATCGCTTCGATGAAGAGAACTTAATTGCGGTGTTTCAAGA
AGCTTGCCACACCTGCCATGGCCCGCAAGAGATTCTGGATTACCTATTTGAGCGCTTGCAAGCTTTTATGGGTGAGCGCA
ACCAAAGTGGTGATGATGTAACCCTGATCGTCATGCAAATCACACCCATGTTGATGACGTTTTAA

Upstream 100 bases:

>100_bases
GCCCAAAGGGTTGACAAGAGTGCTAAGCTTACTGGGCATAACTATCAATAAGTAACGCAACACTCGTTTTCCCCTACGAT
ACTGGCTTGTATTTGCCTTT

Downstream 100 bases:

>100_bases
GAGCGCCGCTTGAGTTTTAACATTCCTTCTAGGGATGTTAGGGGGTGTTGCATAAATGGTAACTCACCCAATAGCGAGGT
TGAAACCCACCATAATCAGG

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSRVPLPNQPSQSLDLDYPGVATNVATVTALQELVSHLRREQAKAQDLLSSLSFSLRSFNNLNQFLALIPLIVSRVTDAD
AAALILFRPNGQVSLEQLYCHEGQQCRNIRLALENVTRQFTVNGSPAKQPNLVLEQQLGHLLGTNYQWFSTAILVRNFEL
HERGRLYLFSSNPDYEWTETRQKLAQLVADQTAVAIENDTLTTQLRKQERITRELEIGAEIQARLLPNYSPKIEGVALAA
TCQTANQVGGDYYDFIPIYRQLPTSRQYRLNQADRWGLVIGDVMGKGVPAGLIMTMTRGILRADALHHHSPAEILKNLNQ
VMYADLENSNRFVTLFYSEYDPKTRQLSFSNAAHNPPLLWRARENVIERLDTDGMLIGLDANTEYQEDKVTLSPGDTIIY
YTDGFTDAAGPNGDRFDEENLIAVFQEACHTCHGPQEILDYLFERLQAFMGERNQSGDDVTLIVMQITPMLMTF

Sequences:

>Translated_474_residues
MSRVPLPNQPSQSLDLDYPGVATNVATVTALQELVSHLRREQAKAQDLLSSLSFSLRSFNNLNQFLALIPLIVSRVTDAD
AAALILFRPNGQVSLEQLYCHEGQQCRNIRLALENVTRQFTVNGSPAKQPNLVLEQQLGHLLGTNYQWFSTAILVRNFEL
HERGRLYLFSSNPDYEWTETRQKLAQLVADQTAVAIENDTLTTQLRKQERITRELEIGAEIQARLLPNYSPKIEGVALAA
TCQTANQVGGDYYDFIPIYRQLPTSRQYRLNQADRWGLVIGDVMGKGVPAGLIMTMTRGILRADALHHHSPAEILKNLNQ
VMYADLENSNRFVTLFYSEYDPKTRQLSFSNAAHNPPLLWRARENVIERLDTDGMLIGLDANTEYQEDKVTLSPGDTIIY
YTDGFTDAAGPNGDRFDEENLIAVFQEACHTCHGPQEILDYLFERLQAFMGERNQSGDDVTLIVMQITPMLMTF
>Mature_473_residues
SRVPLPNQPSQSLDLDYPGVATNVATVTALQELVSHLRREQAKAQDLLSSLSFSLRSFNNLNQFLALIPLIVSRVTDADA
AALILFRPNGQVSLEQLYCHEGQQCRNIRLALENVTRQFTVNGSPAKQPNLVLEQQLGHLLGTNYQWFSTAILVRNFELH
ERGRLYLFSSNPDYEWTETRQKLAQLVADQTAVAIENDTLTTQLRKQERITRELEIGAEIQARLLPNYSPKIEGVALAAT
CQTANQVGGDYYDFIPIYRQLPTSRQYRLNQADRWGLVIGDVMGKGVPAGLIMTMTRGILRADALHHHSPAEILKNLNQV
MYADLENSNRFVTLFYSEYDPKTRQLSFSNAAHNPPLLWRARENVIERLDTDGMLIGLDANTEYQEDKVTLSPGDTIIYY
TDGFTDAAGPNGDRFDEENLIAVFQEACHTCHGPQEILDYLFERLQAFMGERNQSGDDVTLIVMQITPMLMTF

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 53513; Mature: 53382

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVPLPNQPSQSLDLDYPGVATNVATVTALQELVSHLRREQAKAQDLLSSLSFSLRSFN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLNQFLALIPLIVSRVTDADAAALILFRPNGQVSLEQLYCHEGQQCRNIRLALENVTRQF
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHCCCHHHHHHHHHHHHHCEEE
TVNGSPAKQPNLVLEQQLGHLLGTNYQWFSTAILVRNFELHERGRLYLFSSNPDYEWTET
EECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHH
RQKLAQLVADQTAVAIENDTLTTQLRKQERITRELEIGAEIQARLLPNYSPKIEGVALAA
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEE
TCQTANQVGGDYYDFIPIYRQLPTSRQYRLNQADRWGLVIGDVMGKGVPAGLIMTMTRGI
EHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHH
LRADALHHHSPAEILKNLNQVMYADLENSNRFVTLFYSEYDPKTRQLSFSNAAHNPPLLW
HHHHHHCCCCHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCEEE
RARENVIERLDTDGMLIGLDANTEYQEDKVTLSPGDTIIYYTDGFTDAAGPNGDRFDEEN
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCH
LIAVFQEACHTCHGPQEILDYLFERLQAFMGERNQSGDDVTLIVMQITPMLMTF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHCC
>Mature Secondary Structure 
SRVPLPNQPSQSLDLDYPGVATNVATVTALQELVSHLRREQAKAQDLLSSLSFSLRSFN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLNQFLALIPLIVSRVTDADAAALILFRPNGQVSLEQLYCHEGQQCRNIRLALENVTRQF
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEHHHHHHCCCHHHHHHHHHHHHHCEEE
TVNGSPAKQPNLVLEQQLGHLLGTNYQWFSTAILVRNFELHERGRLYLFSSNPDYEWTET
EECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCEEEEEECCCCCCHHHH
RQKLAQLVADQTAVAIENDTLTTQLRKQERITRELEIGAEIQARLLPNYSPKIEGVALAA
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCEEEEE
TCQTANQVGGDYYDFIPIYRQLPTSRQYRLNQADRWGLVIGDVMGKGVPAGLIMTMTRGI
EHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHH
LRADALHHHSPAEILKNLNQVMYADLENSNRFVTLFYSEYDPKTRQLSFSNAAHNPPLLW
HHHHHHCCCCHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCEEE
RARENVIERLDTDGMLIGLDANTEYQEDKVTLSPGDTIIYYTDGFTDAAGPNGDRFDEEN
HHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCCCH
LIAVFQEACHTCHGPQEILDYLFERLQAFMGERNQSGDDVTLIVMQITPMLMTF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]