Click here to switch to the map view.

The map label for this gene is tcrA [H]

Identifier: 158336595

GI number: 158336595

Start: 3496029

End: 3496724

Strand: Reverse

Name: tcrA [H]

Synonym: AM1_3461

Alternate gene names: 158336595

Gene position: 3496724-3496029 (Counterclockwise)

Preceding gene: 158336596

Following gene: 158336594

Centisome position: 53.76

GC content: 52.59

Gene sequence:

>696_bases
ATGCGAGTATTACTGGTCGAAGATGAACCGGATCTGGGCGCTGCCATTCAGCGCACTCTCACCCAGGAAGCTTATATTGT
GGATTGGGCGAAAGATGGCAGGGAAGCTTGGGGCTATCTAGAAAGCCAGTGGACCCAGTACACCCTGGCGATCTTCGACT
GGTTATTGCCGGGATTGTCCGGGATAGATCTGTGCCAGCGACTTCGGGCTCAGCAGAGTCCTTTGCCCGTCCTGATGTTG
ACCGCCAAGGATCAACCGGAAGATACCGCAACAGGGCTGGATGCGGGAGCGGATGATTATCTGGTTAAACCCTTTCGCAA
AATTGAATTACTGGCCCGTTTGCGGGCACTGCAGCGACGATCGCCCCATTTTCAGCCTCAACAACTTCAGGTGGGGCCGC
TCACGTTAGACTATGGCACCCACAATGTCTCTATCCTGAATCAGGAACAAGGTCAGAGCGTCTTGTTGACCCATAAAGAG
TTTCAGCTTTTAGAGTATTTTATGCAGCATCCCCGACAAATTGTGAGTCGCGATCAGATCCTTAACCAGCTTTGGGGCGC
GGAAGCCGACACCATCAGTAATGTGGTAGCTGCCCTTATGCGTCAACTGCGACGTAAGCTAGCTGAACTGGGCTGTGACG
ATGCCATTGAGACCGTCTATGGGGTGGGTTATCGTCTCCATCTAACCCATGAATGA

Upstream 100 bases:

>100_bases
CTGAATTGGAACACTATCGAGATCGCTGGGCCACCAACCAGCCCCGACCTCAACCCGGTGATATCTGTCCTTTGATTTCA
ACCGTTTCCTTGTAACGCTT

Downstream 100 bases:

>100_bases
GCGGACGTTATTTCGTCAGACCCGATGGCGGTTGGCAAGCTGGTATGCCGGGGTGATGGGTATTATTTTGACCCTCAGTG
GCTTTGGTGTCTATGAGGCG

Product: two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRVLLVEDEPDLGAAIQRTLTQEAYIVDWAKDGREAWGYLESQWTQYTLAIFDWLLPGLSGIDLCQRLRAQQSPLPVLML
TAKDQPEDTATGLDAGADDYLVKPFRKIELLARLRALQRRSPHFQPQQLQVGPLTLDYGTHNVSILNQEQGQSVLLTHKE
FQLLEYFMQHPRQIVSRDQILNQLWGAEADTISNVVAALMRQLRRKLAELGCDDAIETVYGVGYRLHLTHE

Sequences:

>Translated_231_residues
MRVLLVEDEPDLGAAIQRTLTQEAYIVDWAKDGREAWGYLESQWTQYTLAIFDWLLPGLSGIDLCQRLRAQQSPLPVLML
TAKDQPEDTATGLDAGADDYLVKPFRKIELLARLRALQRRSPHFQPQQLQVGPLTLDYGTHNVSILNQEQGQSVLLTHKE
FQLLEYFMQHPRQIVSRDQILNQLWGAEADTISNVVAALMRQLRRKLAELGCDDAIETVYGVGYRLHLTHE
>Mature_231_residues
MRVLLVEDEPDLGAAIQRTLTQEAYIVDWAKDGREAWGYLESQWTQYTLAIFDWLLPGLSGIDLCQRLRAQQSPLPVLML
TAKDQPEDTATGLDAGADDYLVKPFRKIELLARLRALQRRSPHFQPQQLQVGPLTLDYGTHNVSILNQEQGQSVLLTHKE
FQLLEYFMQHPRQIVSRDQILNQLWGAEADTISNVVAALMRQLRRKLAELGCDDAIETVYGVGYRLHLTHE

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=37.5545851528384, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.117903930131, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.5, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=38.0530973451327, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=35.2422907488987, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=36.283185840708, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=34.7639484978541, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.7758620689655, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=29.3103448275862, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.0429184549356, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=28.2700421940928, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26362; Mature: 26362

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDEPDLGAAIQRTLTQEAYIVDWAKDGREAWGYLESQWTQYTLAIFDWLLPGLS
CEEEEECCCCCHHHHHHHHHHHHHEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIDLCQRLRAQQSPLPVLMLTAKDQPEDTATGLDAGADDYLVKPFRKIELLARLRALQRR
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
SPHFQPQQLQVGPLTLDYGTHNVSILNQEQGQSVLLTHKEFQLLEYFMQHPRQIVSRDQI
CCCCCCCCEEECCEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LNQLWGAEADTISNVVAALMRQLRRKLAELGCDDAIETVYGVGYRLHLTHE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MRVLLVEDEPDLGAAIQRTLTQEAYIVDWAKDGREAWGYLESQWTQYTLAIFDWLLPGLS
CEEEEECCCCCHHHHHHHHHHHHHEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GIDLCQRLRAQQSPLPVLMLTAKDQPEDTATGLDAGADDYLVKPFRKIELLARLRALQRR
HHHHHHHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
SPHFQPQQLQVGPLTLDYGTHNVSILNQEQGQSVLLTHKEFQLLEYFMQHPRQIVSRDQI
CCCCCCCCEEECCEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LNQLWGAEADTISNVVAALMRQLRRKLAELGCDDAIETVYGVGYRLHLTHE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]