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The map label for this gene is trxB [H]

Identifier: 158336488

GI number: 158336488

Start: 3386331

End: 3387287

Strand: Reverse

Name: trxB [H]

Synonym: AM1_3352

Alternate gene names: 158336488

Gene position: 3387287-3386331 (Counterclockwise)

Preceding gene: 158336489

Following gene: 158336486

Centisome position: 52.08

GC content: 47.75

Gene sequence:

>957_bases
TTGGATACCTATGAATTTGATGTTGTGATTATTGGTGGTGGTCCTGCAGGCTGTACCTGTGCCCTCTACACATCGCGAGC
GAATTTCAAGACGGTTATTTTAGACAAAAACCCTGCTGTAGGTGCTTTGGCCATCACTCATAAAATTGCCAACTATCCTG
GAGTTGCCGGTGATATCAGTGGCGAAGAACTCTTGACTGTCATGAGAGAGCAAGCCATGGAGTTTGGCACGCACTATCAG
CAAGCACAAGTCTTTGGTCTAGATATTACCGGTGCCCAAAAAAAGGTTTACACCCCTGAAGGGACATTTGTGGGCCGAGC
GATTGTATTAGCCACAGGGGCAATGGGTCGCAAGGCCTCTTTTGATGGAGAAGCTGAGTTTTTAGGTCGGGGAGTCAGCT
ACTGCGCCACCTGTGATGCCGCTTTTTACAAAGATCGGCCTGTTGCAGTTGTAGGGCTGAACCGTGAAGCCATTGAGGAA
GCTCAAGTCCTCACTAAATTTTCGTCTATGGTTCACTGGGTAACCGTAAAGACCCCGCCAGCGGAAGATACCCATGCTCA
GGATTTGCTAAGTTTACCCAATGTGAAACATTGGAGCCGATCTAGGCTGCTATCAATTCAGGGTAGCGACATGGGCGTTT
CAGGGGTACAAGTTAAGGTCAGAGATCAAGATGAACCAATCGGTTTAGAGGTGGATGGGGTATTTGTCTATCAAAATGGC
TCCAAACCTATTACTGATTTTGTAGGTGATCAAGTTCACTTCAATCCCGATGGTGGAGTCAAGGTTGATGAACTGATGGC
AACCAGTGTAGATGGTGTGTGGGCTATTGGAGATATCCGCAATACCCCTTTTAAGCAAGCGGTGGTTGCAGCGGGAGATG
GGTGTGTGGCCGCAATGGCGATTGATCGCTTTCTCAATAGTCGCAAGCTATTTAAACCAGACTGGGATCATTCCTAA

Upstream 100 bases:

>100_bases
CAAGTATGCCTCGCCTATCCTCCACCCACGAACAGCTCATGATGACGCTGTTATGCAAGGAAATGAAGAATTCTGCCCTA
CTTCCTGGAGACTAAAGACC

Downstream 100 bases:

>100_bases
CTCAACTGACCGAGACCAGGTCACTCCCGTTGGCTCACAAAATAGTGATGTGTTGCTCGATCCACCAATGCGCCACTTTC
TGTGAGCATGTGAATTTCTC

Product: pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDTYEFDVVIIGGGPAGCTCALYTSRANFKTVILDKNPAVGALAITHKIANYPGVAGDISGEELLTVMREQAMEFGTHYQ
QAQVFGLDITGAQKKVYTPEGTFVGRAIVLATGAMGRKASFDGEAEFLGRGVSYCATCDAAFYKDRPVAVVGLNREAIEE
AQVLTKFSSMVHWVTVKTPPAEDTHAQDLLSLPNVKHWSRSRLLSIQGSDMGVSGVQVKVRDQDEPIGLEVDGVFVYQNG
SKPITDFVGDQVHFNPDGGVKVDELMATSVDGVWAIGDIRNTPFKQAVVAAGDGCVAAMAIDRFLNSRKLFKPDWDHS

Sequences:

>Translated_318_residues
MDTYEFDVVIIGGGPAGCTCALYTSRANFKTVILDKNPAVGALAITHKIANYPGVAGDISGEELLTVMREQAMEFGTHYQ
QAQVFGLDITGAQKKVYTPEGTFVGRAIVLATGAMGRKASFDGEAEFLGRGVSYCATCDAAFYKDRPVAVVGLNREAIEE
AQVLTKFSSMVHWVTVKTPPAEDTHAQDLLSLPNVKHWSRSRLLSIQGSDMGVSGVQVKVRDQDEPIGLEVDGVFVYQNG
SKPITDFVGDQVHFNPDGGVKVDELMATSVDGVWAIGDIRNTPFKQAVVAAGDGCVAAMAIDRFLNSRKLFKPDWDHS
>Mature_318_residues
MDTYEFDVVIIGGGPAGCTCALYTSRANFKTVILDKNPAVGALAITHKIANYPGVAGDISGEELLTVMREQAMEFGTHYQ
QAQVFGLDITGAQKKVYTPEGTFVGRAIVLATGAMGRKASFDGEAEFLGRGVSYCATCDAAFYKDRPVAVVGLNREAIEE
AQVLTKFSSMVHWVTVKTPPAEDTHAQDLLSLPNVKHWSRSRLLSIQGSDMGVSGVQVKVRDQDEPIGLEVDGVFVYQNG
SKPITDFVGDQVHFNPDGGVKVDELMATSVDGVWAIGDIRNTPFKQAVVAAGDGCVAAMAIDRFLNSRKLFKPDWDHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=33.3333333333333, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=28.7096774193548, Blast_Score=102, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=33.015873015873, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=32.9073482428115, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34268; Mature: 34268

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTYEFDVVIIGGGPAGCTCALYTSRANFKTVILDKNPAVGALAITHKIANYPGVAGDIS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEHHHHCCCCCCCCCC
GEELLTVMREQAMEFGTHYQQAQVFGLDITGAQKKVYTPEGTFVGRAIVLATGAMGRKAS
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCCCCEEEEEEECCCCCCCC
FDGEAEFLGRGVSYCATCDAAFYKDRPVAVVGLNREAIEEAQVLTKFSSMVHWVTVKTPP
CCCCHHHHHCCCHHEEECCHHHCCCCCEEEEECCHHHHHHHHHHHHHHCEEEEEEEECCC
AEDTHAQDLLSLPNVKHWSRSRLLSIQGSDMGVSGVQVKVRDQDEPIGLEVDGVFVYQNG
CCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEECC
SKPITDFVGDQVHFNPDGGVKVDELMATSVDGVWAIGDIRNTPFKQAVVAAGDGCVAAMA
CCCHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHEEECCCCHHHHHH
IDRFLNSRKLFKPDWDHS
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDTYEFDVVIIGGGPAGCTCALYTSRANFKTVILDKNPAVGALAITHKIANYPGVAGDIS
CCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEHHHHCCCCCCCCCC
GEELLTVMREQAMEFGTHYQQAQVFGLDITGAQKKVYTPEGTFVGRAIVLATGAMGRKAS
HHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCCCCEEEEEEECCCCCCCC
FDGEAEFLGRGVSYCATCDAAFYKDRPVAVVGLNREAIEEAQVLTKFSSMVHWVTVKTPP
CCCCHHHHHCCCHHEEECCHHHCCCCCEEEEECCHHHHHHHHHHHHHHCEEEEEEEECCC
AEDTHAQDLLSLPNVKHWSRSRLLSIQGSDMGVSGVQVKVRDQDEPIGLEVDGVFVYQNG
CCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEEEEEEEEECC
SKPITDFVGDQVHFNPDGGVKVDELMATSVDGVWAIGDIRNTPFKQAVVAAGDGCVAAMA
CCCHHHHCCCEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCHHHHEEECCCCHHHHHH
IDRFLNSRKLFKPDWDHS
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]