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The map label for this gene is wecB [C]

Identifier: 158336256

GI number: 158336256

Start: 3146381

End: 3147496

Strand: Reverse

Name: wecB [C]

Synonym: AM1_3118

Alternate gene names: 158336256

Gene position: 3147496-3146381 (Counterclockwise)

Preceding gene: 158336257

Following gene: 158336255

Centisome position: 48.4

GC content: 48.03

Gene sequence:

>1116_bases
ATGCCAAATTCTCCCCTTCCGATCTGTATCGTCTTAGGGACGCGTCCAGAAGCCATTAAACTTGCCCCCGTCATTCAAGC
CTTTCGGGCTGATGCTCGATTCGCCACTCAAGTCTTATTAACGGGACAACATAAAGAAATGGTCGACCAAGTGATGCAAA
TCTTCGATCTCGAAGCTGACCATAACTTAGATATCATGCAAGCCAAACAAACTTTAGCTGACATCACTTGTCGGAGTTTG
CAAGGACTACAGACCCTTTTACAAGAACTACACCCCAAAGCGGTTCTAGTACAGGGAGACACAACAACTGCCTTTGCTGC
AGGCCTAGCCGCCTTTTATCAACAAATTCCTGTCGGCCATGTTGAAGCAGGCTTACGCACTGATAATATCTACAACCCTT
ATCCAGAAGAAGCTAACCGGCGCTTAATCTCTCAAATCACCCAACTCCACTTTGCACCTACCACTAAAGCTGTAGAAAAC
TTAAAAGCTTCCGGAGTTACAGGAACGATTCACCACACTGGCAACACCGTTATTGATGCCCTACTGACCGTCGCGGACAA
ACACCCCTCCTGCAATATTCCCAATTTAGACTGGAGCCAGTATCGAACCATTCTGGCAACCGTTCATCGTCGAGAAAACT
GGGGCGCCCCCTTACAGGATATTGCCCAGGGGTTCCTCCAAGTTCTAGACAAATTTCCTGATACCGCACTAATTCTGCCG
CTCCACCGTAACCCAACCGTTAGAGAGCCCTTAACGGCAATCTTGGGGAACCATCCGCGCATTTTCTTAACTGAGCCTCT
GGACTATACTGATTTAGTCGGTGCTATTCAGCGATGTCATCTGTTACTGACAGACTCTGGAGGGTTGCAAGAAGAAGCTC
CCAGTCTTGGTAAACCTGTCTTAGTCTTAAGAGAAACCACCGAAAGACCTGAAGCCGTGACAGCCGGTACCGCCAAGCTG
ATCGGCACCAGTACCCAAAAAATCTTGGCCGAAGCTAGCCTGCTCTTAGAAAATGAAGAGGCTTACAACGATATGGCCAA
AGCCATTAACCCCTTTGGAGATGGACAAGCGTCCCAACGGATCATCACCGCTATTCAAGATTTTCTGCAGCTTTAA

Upstream 100 bases:

>100_bases
TGCGCCTCTCTTTTACGATAAACATGAGTTATCTTGAAGCTTGAGCCCGGTTTAACCGGGTTTTTCAGTAGTATGGTCTT
TATGCATTTCTAGCGTCAGC

Downstream 100 bases:

>100_bases
TTTCCGAAATTCTAGATTTTCATAGGTTCTCAATTGATGTATGCAGATAAAGAGCCCTTAGACCCTAGAGAGATGACCAC
CCCAAATGCCATAATGACGA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPNSPLPICIVLGTRPEAIKLAPVIQAFRADARFATQVLLTGQHKEMVDQVMQIFDLEADHNLDIMQAKQTLADITCRSL
QGLQTLLQELHPKAVLVQGDTTTAFAAGLAAFYQQIPVGHVEAGLRTDNIYNPYPEEANRRLISQITQLHFAPTTKAVEN
LKASGVTGTIHHTGNTVIDALLTVADKHPSCNIPNLDWSQYRTILATVHRRENWGAPLQDIAQGFLQVLDKFPDTALILP
LHRNPTVREPLTAILGNHPRIFLTEPLDYTDLVGAIQRCHLLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKL
IGTSTQKILAEASLLLENEEAYNDMAKAINPFGDGQASQRIITAIQDFLQL

Sequences:

>Translated_371_residues
MPNSPLPICIVLGTRPEAIKLAPVIQAFRADARFATQVLLTGQHKEMVDQVMQIFDLEADHNLDIMQAKQTLADITCRSL
QGLQTLLQELHPKAVLVQGDTTTAFAAGLAAFYQQIPVGHVEAGLRTDNIYNPYPEEANRRLISQITQLHFAPTTKAVEN
LKASGVTGTIHHTGNTVIDALLTVADKHPSCNIPNLDWSQYRTILATVHRRENWGAPLQDIAQGFLQVLDKFPDTALILP
LHRNPTVREPLTAILGNHPRIFLTEPLDYTDLVGAIQRCHLLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKL
IGTSTQKILAEASLLLENEEAYNDMAKAINPFGDGQASQRIITAIQDFLQL
>Mature_370_residues
PNSPLPICIVLGTRPEAIKLAPVIQAFRADARFATQVLLTGQHKEMVDQVMQIFDLEADHNLDIMQAKQTLADITCRSLQ
GLQTLLQELHPKAVLVQGDTTTAFAAGLAAFYQQIPVGHVEAGLRTDNIYNPYPEEANRRLISQITQLHFAPTTKAVENL
KASGVTGTIHHTGNTVIDALLTVADKHPSCNIPNLDWSQYRTILATVHRRENWGAPLQDIAQGFLQVLDKFPDTALILPL
HRNPTVREPLTAILGNHPRIFLTEPLDYTDLVGAIQRCHLLLTDSGGLQEEAPSLGKPVLVLRETTERPEAVTAGTAKLI
GTSTQKILAEASLLLENEEAYNDMAKAINPFGDGQASQRIITAIQDFLQL

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:
GO:0006047: UDP-N-acetylglucosamine 2-epimerase
GO:0008761: UDP-N-acetylglucosamine 2-epimerase
GO:0009103: UDP-N-acetylglucosamine 2-epimerase
GO:0016853: UDP-N-acetylglucosamine 2-epimerase

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=48.6559139784946, Blast_Score=343, Evalue=9e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40678; Mature: 40547

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSPLPICIVLGTRPEAIKLAPVIQAFRADARFATQVLLTGQHKEMVDQVMQIFDLEAD
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
HNLDIMQAKQTLADITCRSLQGLQTLLQELHPKAVLVQGDTTTAFAAGLAAFYQQIPVGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCH
VEAGLRTDNIYNPYPEEANRRLISQITQLHFAPTTKAVENLKASGVTGTIHHTGNTVIDA
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
LLTVADKHPSCNIPNLDWSQYRTILATVHRRENWGAPLQDIAQGFLQVLDKFPDTALILP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
LHRNPTVREPLTAILGNHPRIFLTEPLDYTDLVGAIQRCHLLLTDSGGLQEEAPSLGKPV
ECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCCCCHHCCCCCCCE
LVLRETTERPEAVTAGTAKLIGTSTQKILAEASLLLENEEAYNDMAKAINPFGDGQASQR
EEEECCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHH
IITAIQDFLQL
HHHHHHHHHCC
>Mature Secondary Structure 
PNSPLPICIVLGTRPEAIKLAPVIQAFRADARFATQVLLTGQHKEMVDQVMQIFDLEAD
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
HNLDIMQAKQTLADITCRSLQGLQTLLQELHPKAVLVQGDTTTAFAAGLAAFYQQIPVGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCH
VEAGLRTDNIYNPYPEEANRRLISQITQLHFAPTTKAVENLKASGVTGTIHHTGNTVIDA
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCHHHHHH
LLTVADKHPSCNIPNLDWSQYRTILATVHRRENWGAPLQDIAQGFLQVLDKFPDTALILP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
LHRNPTVREPLTAILGNHPRIFLTEPLDYTDLVGAIQRCHLLLTDSGGLQEEAPSLGKPV
ECCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCCCCHHCCCCCCCE
LVLRETTERPEAVTAGTAKLIGTSTQKILAEASLLLENEEAYNDMAKAINPFGDGQASQR
EEEECCCCCCCHHHCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHH
IITAIQDFLQL
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]