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The map label for this gene is wzb [C]

Identifier: 158336239

GI number: 158336239

Start: 3131610

End: 3132080

Strand: Reverse

Name: wzb [C]

Synonym: AM1_3100

Alternate gene names: 158336239

Gene position: 3132080-3131610 (Counterclockwise)

Preceding gene: 158336240

Following gene: 158336237

Centisome position: 48.16

GC content: 47.56

Gene sequence:

>471_bases
ATGCCCCAAAAGCTTTTGTTTGTCTGTCTAGGCAATATTTGCCGCTCCCCCTCTGCCGAAGGGATTATGAATCACCTGCT
GCAGCAAGAGCAGCTCACCCATGAATACCAATGTGATTCTGCAGGCACTAGCAGCTATCATATTGGCGCTTCTCCAGACC
GGAGAATGGCGGCAGCTGGCTTACGACAAGGTATCGTACTCACCGGCAACAGCCGCCAAGTTGAACCAGAAGATTTTGCG
GAGTTCGATCTAATTCTGGCCATGGATCGCCAAAACTACCGCGATTTGGTAGCCATGAATCCAGATGAGCAATATGCCGA
TAAAATCCACATGATGTGCGATTTTTGCTCTAATTTTGCCGATAAAGAGGTGCCCGATCCTTATTATGGAGGGCCTTCAG
GGTTTGATTATGTGATTGATCTTCTGCTGGATGCTTGCAGTGGCTTATTGGATCATTTGCACAAATCTTAG

Upstream 100 bases:

>100_bases
TCGAACAGGGACCGCTGGCCCGCTTGCACTTAAAGCACCATATCCCCTACGGTTTACATGGCAGTTTTACGCCAACGCTG
TTTTAACCGGTCCCAACCCG

Downstream 100 bases:

>100_bases
GGATCGTTCTCTATCGCCCCTAATAAATTATGTTCCATGGCAAACCTGACGATTTCGGCTCGATTGCTGGTTTCTGTTTT
TTGCAAGAGCTTACTCACAT

Product: low molecular weight protein-tyrosine-phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MPQKLLFVCLGNICRSPSAEGIMNHLLQQEQLTHEYQCDSAGTSSYHIGASPDRRMAAAGLRQGIVLTGNSRQVEPEDFA
EFDLILAMDRQNYRDLVAMNPDEQYADKIHMMCDFCSNFADKEVPDPYYGGPSGFDYVIDLLLDACSGLLDHLHKS

Sequences:

>Translated_156_residues
MPQKLLFVCLGNICRSPSAEGIMNHLLQQEQLTHEYQCDSAGTSSYHIGASPDRRMAAAGLRQGIVLTGNSRQVEPEDFA
EFDLILAMDRQNYRDLVAMNPDEQYADKIHMMCDFCSNFADKEVPDPYYGGPSGFDYVIDLLLDACSGLLDHLHKS
>Mature_155_residues
PQKLLFVCLGNICRSPSAEGIMNHLLQQEQLTHEYQCDSAGTSSYHIGASPDRRMAAAGLRQGIVLTGNSRQVEPEDFAE
FDLILAMDRQNYRDLVAMNPDEQYADKIHMMCDFCSNFADKEVPDPYYGGPSGFDYVIDLLLDACSGLLDHLHKS

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=157, Percent_Identity=38.2165605095541, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI6005988, Length=157, Percent_Identity=35.6687898089172, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=42.8571428571429, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=136, Percent_Identity=34.5588235294118, Blast_Score=97, Evalue=8e-22,
Organism=Drosophila melanogaster, GI78706770, Length=149, Percent_Identity=36.241610738255, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706772, Length=149, Percent_Identity=36.241610738255, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706766, Length=151, Percent_Identity=33.7748344370861, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI78706768, Length=151, Percent_Identity=33.7748344370861, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI78711846, Length=152, Percent_Identity=33.5526315789474, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI78706764, Length=129, Percent_Identity=35.6589147286822, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648069, Length=123, Percent_Identity=30.8943089430894, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17436; Mature: 17305

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKLLFVCLGNICRSPSAEGIMNHLLQQEQLTHEYQCDSAGTSSYHIGASPDRRMAAAG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHH
LRQGIVLTGNSRQVEPEDFAEFDLILAMDRQNYRDLVAMNPDEQYADKIHMMCDFCSNFA
HHCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHC
DKEVPDPYYGGPSGFDYVIDLLLDACSGLLDHLHKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQKLLFVCLGNICRSPSAEGIMNHLLQQEQLTHEYQCDSAGTSSYHIGASPDRRMAAAG
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHH
LRQGIVLTGNSRQVEPEDFAEFDLILAMDRQNYRDLVAMNPDEQYADKIHMMCDFCSNFA
HHCCEEEECCCCCCCHHHHHHHHHHEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHC
DKEVPDPYYGGPSGFDYVIDLLLDACSGLLDHLHKS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]