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The map label for this gene is 158336168

Identifier: 158336168

GI number: 158336168

Start: 3054595

End: 3055584

Strand: Reverse

Name: 158336168

Synonym: AM1_3030

Alternate gene names: NA

Gene position: 3055584-3054595 (Counterclockwise)

Preceding gene: 158336169

Following gene: 158336167

Centisome position: 46.98

GC content: 54.65

Gene sequence:

>990_bases
GTGACGGCCATTGCCTGGTCACCCAATAGCCAGCAGGTGGCCGCCTGCGATGGAGCGGGTAATGTTCAATGTCTCAATCG
AATCACCCAACAAACCCATAGTCTGCAAACGGGCACCGGACAGTCAGTGGATGCATTGGCTTACTCCGCTGATGGCCGTT
TTCTCGCAGCAGGAGGGCAAGATGGCCGTGTTTCGATTTGGGAGATGAGCGGCGACGCACCGACGCTGTTTACCTGTTTA
GAGAACCCTCGCACCTGGGTGGATCAACTGGCCTGGCATCCTCGGCGTCCAGAATTGGTGTTTAGCCTGGGGCGCTATGC
CCAGGTTTGGGAGGTTGAGACCCAGCAAGTCCTGACGACTCTCGCCTTTGAAAACTCTTCCGTTTTAGATTTAGCCTGGC
ATCCGCAACAGGATTGGCTGGCGGTCGGTGGCCATCAAGGGGTCAAAATTTGGCAGGATTGGGATCAAGATCCCGCCATT
CGAGAGCTTCCAGGATCGAGTATCTGTGTCTCTTGGTCGCCGGACGGGCAATATTTAGCGTCAGGAAATTTAGATCGCAC
TATGGTGGTGTGGCCTTCAGAAGAAGACGTACCCTGGCGGATGACGGGTTTCCCTGGCAAAGTTCGGCAAATAGCCTGGT
CAGCGGATGCTGAATCCGTTGATGCTGACCCCCTGCTGTCCGCAGCCAGTGGTAACTGCATTACGACTTGGCACCGCCTA
GGCAGTGGCTGGGAAGCAGAGCTGTTAGAAGAGCACACGCAAGCAGTCAATGCCATTGCCTTTCAGCCTAATACCACTCT
TTTAGTATCTGCTGCAGCGGATGACTTTCTCTGTCTGTGGCAAGGTGGGGGTAAGCTAGTCCAAGCGCAAAAAAGTATCA
GTGGTTCAGCCCTGGCTTGGAGTCCAGATGGTCAGACCCTAGCTTTAGGGGGCCAGCAAGGAGAATGGCAGCTTTGGACC
CAAAGTGCACGAGGTCAAGGATTTTTCTAG

Upstream 100 bases:

>100_bases
GCAATTTAGATGAAGATCAGTTAAGAAAGGGGTTCCAAGCTTGCCTCGTGTAACTCAGCCACGACTTGGACGCAAATGGC
GTGGGCGTTTAGATGATTAT

Downstream 100 bases:

>100_bases
TTGTTGAATGGGGAGTAGTTCTAATGGATTTGTTTAAAGCATCCACGCCTAAAGCGGATCCAGAACAGATTGCACGGCTG
AAAGCCTGGGTGTATGAAGC

Product: WD repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTAIAWSPNSQQVAACDGAGNVQCLNRITQQTHSLQTGTGQSVDALAYSADGRFLAAGGQDGRVSIWEMSGDAPTLFTCL
ENPRTWVDQLAWHPRRPELVFSLGRYAQVWEVETQQVLTTLAFENSSVLDLAWHPQQDWLAVGGHQGVKIWQDWDQDPAI
RELPGSSICVSWSPDGQYLASGNLDRTMVVWPSEEDVPWRMTGFPGKVRQIAWSADAESVDADPLLSAASGNCITTWHRL
GSGWEAELLEEHTQAVNAIAFQPNTTLLVSAAADDFLCLWQGGGKLVQAQKSISGSALAWSPDGQTLALGGQQGEWQLWT
QSARGQGFF

Sequences:

>Translated_329_residues
MTAIAWSPNSQQVAACDGAGNVQCLNRITQQTHSLQTGTGQSVDALAYSADGRFLAAGGQDGRVSIWEMSGDAPTLFTCL
ENPRTWVDQLAWHPRRPELVFSLGRYAQVWEVETQQVLTTLAFENSSVLDLAWHPQQDWLAVGGHQGVKIWQDWDQDPAI
RELPGSSICVSWSPDGQYLASGNLDRTMVVWPSEEDVPWRMTGFPGKVRQIAWSADAESVDADPLLSAASGNCITTWHRL
GSGWEAELLEEHTQAVNAIAFQPNTTLLVSAAADDFLCLWQGGGKLVQAQKSISGSALAWSPDGQTLALGGQQGEWQLWT
QSARGQGFF
>Mature_328_residues
TAIAWSPNSQQVAACDGAGNVQCLNRITQQTHSLQTGTGQSVDALAYSADGRFLAAGGQDGRVSIWEMSGDAPTLFTCLE
NPRTWVDQLAWHPRRPELVFSLGRYAQVWEVETQQVLTTLAFENSSVLDLAWHPQQDWLAVGGHQGVKIWQDWDQDPAIR
ELPGSSICVSWSPDGQYLASGNLDRTMVVWPSEEDVPWRMTGFPGKVRQIAWSADAESVDADPLLSAASGNCITTWHRLG
SGWEAELLEEHTQAVNAIAFQPNTTLLVSAAADDFLCLWQGGGKLVQAQKSISGSALAWSPDGQTLALGGQQGEWQLWTQ
SARGQGFF

Specific function: Unknown

COG id: COG2319

COG function: function code R; FOG: WD40 repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 13 WD repeats [H]

Homologues:

Organism=Homo sapiens, GI62234461, Length=381, Percent_Identity=24.9343832020997, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4757988, Length=306, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19913371, Length=335, Percent_Identity=21.4925373134328, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI83779014, Length=276, Percent_Identity=25, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI19913367, Length=287, Percent_Identity=21.2543554006969, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19913365, Length=287, Percent_Identity=21.2543554006969, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI15150805, Length=287, Percent_Identity=21.2543554006969, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI213021190, Length=287, Percent_Identity=20.9059233449477, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI213021188, Length=287, Percent_Identity=20.9059233449477, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI213021186, Length=287, Percent_Identity=20.9059233449477, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI5032159, Length=287, Percent_Identity=20.9059233449477, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17536759, Length=331, Percent_Identity=26.2839879154079, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320056, Length=213, Percent_Identity=25.8215962441315, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17137500, Length=278, Percent_Identity=24.4604316546763, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI18858099, Length=281, Percent_Identity=24.1992882562278, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020472
- InterPro:   IPR011600
- InterPro:   IPR015943
- InterPro:   IPR001680
- InterPro:   IPR011046
- InterPro:   IPR019782
- InterPro:   IPR019775
- InterPro:   IPR017986
- InterPro:   IPR019781 [H]

Pfam domain/function: PF00656 Peptidase_C14; PF00400 WD40 [H]

EC number: NA

Molecular weight: Translated: 35868; Mature: 35737

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00678 WD_REPEATS_1 ; PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIAWSPNSQQVAACDGAGNVQCLNRITQQTHSLQTGTGQSVDALAYSADGRFLAAGGQ
CCEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCC
DGRVSIWEMSGDAPTLFTCLENPRTWVDQLAWHPRRPELVFSLGRYAQVWEVETQQVLTT
CCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHH
LAFENSSVLDLAWHPQQDWLAVGGHQGVKIWQDWDQDPAIRELPGSSICVSWSPDGQYLA
HEECCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCHHHCCCCEEEEEECCCCCEEE
SGNLDRTMVVWPSEEDVPWRMTGFPGKVRQIAWSADAESVDADPLLSAASGNCITTWHRL
CCCCCEEEEEECCCCCCCEEECCCCCHHEEEEECCCCCCCCCCCHHHCCCCCEEEEHHHC
GSGWEAELLEEHTQAVNAIAFQPNTTLLVSAAADDFLCLWQGGGKLVQAQKSISGSALAW
CCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCEEEEECCCCEEEEEHHCCCCCEEEE
SPDGQTLALGGQQGEWQLWTQSARGQGFF
CCCCCEEEECCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TAIAWSPNSQQVAACDGAGNVQCLNRITQQTHSLQTGTGQSVDALAYSADGRFLAAGGQ
CEEEECCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCC
DGRVSIWEMSGDAPTLFTCLENPRTWVDQLAWHPRRPELVFSLGRYAQVWEVETQQVLTT
CCEEEEEEECCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHCCCEEEEEHHHHHHHHH
LAFENSSVLDLAWHPQQDWLAVGGHQGVKIWQDWDQDPAIRELPGSSICVSWSPDGQYLA
HEECCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCHHHCCCCEEEEEECCCCCEEE
SGNLDRTMVVWPSEEDVPWRMTGFPGKVRQIAWSADAESVDADPLLSAASGNCITTWHRL
CCCCCEEEEEECCCCCCCEEECCCCCHHEEEEECCCCCCCCCCCHHHCCCCCEEEEHHHC
GSGWEAELLEEHTQAVNAIAFQPNTTLLVSAAADDFLCLWQGGGKLVQAQKSISGSALAW
CCCCHHHHHHHHHHHHEEEEECCCCEEEEEECCCCEEEEECCCCEEEEEHHCCCCCEEEE
SPDGQTLALGGQQGEWQLWTQSARGQGFF
CCCCCEEEECCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]