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The map label for this gene is glcK [H]

Identifier: 158336055

GI number: 158336055

Start: 2949382

End: 2950266

Strand: Reverse

Name: glcK [H]

Synonym: AM1_2913

Alternate gene names: 158336055

Gene position: 2950266-2949382 (Counterclockwise)

Preceding gene: 158336056

Following gene: 158336050

Centisome position: 45.36

GC content: 52.09

Gene sequence:

>885_bases
ATGACCGAGAACCTGGTACTAGGGATTGATTTAGGAGGGACAGCGATTAAGCTGGGTTGCTGTAGCCCTCAAGGTACTTG
TGTGCGCTCGATTACGGTGCCGACACCACAACCCTCTACGCCTGAACCCGTGGTGGATGCGATCTCAACGGCAGTTCACG
CTTTAGATCCCGATAAAACGCTTCCAGTAATTGGTATTGGCATGCCCGGACCGGCTGATAATACGGGCCGTATTGCTAGG
GTCTCCATCAACTTGGATGATTGGTTAGATGTACCCTTAGCAGAGTGGATAGAAGATAAAACGGGACGACCCACTACCAT
TGCCAATGATGCCAATTGTGCAGGACTCGGCGAAGCTCTCTATGGAGCCGGACAGTCTTTTCAGAACTTGATTATGCTCA
CCTTAGGTACGGGAGTGGGCGGTGCCATCATTATGAATGGCGAGCTGTATACCGGGCGAGATGGGGCGGCGGGGGAATTA
GGACTGATTACCCTTTGGCCCGATGGTCCCCCCTGCAATAGCGGTAATAATGGTTCTCTAGAGCAATTTGCCTCGGTACG
TGCCATTCGCCGAGACCATCAGTGTGAGCCCCATGAGTTAGCGGTGCGAGAAGACGAAAGTGCGATCGCATTTTGGCAAG
ATTATGGTCGGAACTTAGGTGCAGGATTAGCCAGCCTGATCTATGTACTGACGCCTGAAGCAGTGATTTTAGGGGGTGGA
ATTGCAGCGAGTACTGAGTTATTTCTACCCTGGGTGCAAGCAGAAATCGAGCGTCGGGTGATGCCAACGTCTCGGGAAAA
TTTAGTGATTCTGCCTGCTGCTTTGGGCAACCAGGCAGGGATGATTGGAGCGGCTCAATTAGCTCGACAGCGGTTCGGAT
ACTAA

Upstream 100 bases:

>100_bases
ATGAAAAGCTCGGACCCGTAGGACAAGAGCAGGGTATTTGCTCCTATGCAGTAGCATTATTGACCTCAGATTCGTAGATG
AGAGCTGAGTAAGATCTGCG

Downstream 100 bases:

>100_bases
GGGTTCTGCAGGTGTACTGTCATGATGATTCGCATTGTTGCCGTTGTCTGCTAGACAGGCACCCACTAATCCGGCAAAAA
GAGGATGGGGGTCATTGGGG

Product: sugar kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MTENLVLGIDLGGTAIKLGCCSPQGTCVRSITVPTPQPSTPEPVVDAISTAVHALDPDKTLPVIGIGMPGPADNTGRIAR
VSINLDDWLDVPLAEWIEDKTGRPTTIANDANCAGLGEALYGAGQSFQNLIMLTLGTGVGGAIIMNGELYTGRDGAAGEL
GLITLWPDGPPCNSGNNGSLEQFASVRAIRRDHQCEPHELAVREDESAIAFWQDYGRNLGAGLASLIYVLTPEAVILGGG
IAASTELFLPWVQAEIERRVMPTSRENLVILPAALGNQAGMIGAAQLARQRFGY

Sequences:

>Translated_294_residues
MTENLVLGIDLGGTAIKLGCCSPQGTCVRSITVPTPQPSTPEPVVDAISTAVHALDPDKTLPVIGIGMPGPADNTGRIAR
VSINLDDWLDVPLAEWIEDKTGRPTTIANDANCAGLGEALYGAGQSFQNLIMLTLGTGVGGAIIMNGELYTGRDGAAGEL
GLITLWPDGPPCNSGNNGSLEQFASVRAIRRDHQCEPHELAVREDESAIAFWQDYGRNLGAGLASLIYVLTPEAVILGGG
IAASTELFLPWVQAEIERRVMPTSRENLVILPAALGNQAGMIGAAQLARQRFGY
>Mature_293_residues
TENLVLGIDLGGTAIKLGCCSPQGTCVRSITVPTPQPSTPEPVVDAISTAVHALDPDKTLPVIGIGMPGPADNTGRIARV
SINLDDWLDVPLAEWIEDKTGRPTTIANDANCAGLGEALYGAGQSFQNLIMLTLGTGVGGAIIMNGELYTGRDGAAGELG
LITLWPDGPPCNSGNNGSLEQFASVRAIRRDHQCEPHELAVREDESAIAFWQDYGRNLGAGLASLIYVLTPEAVILGGGI
AASTELFLPWVQAEIERRVMPTSRENLVILPAALGNQAGMIGAAQLARQRFGY

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=267, Percent_Identity=28.4644194756554, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI298566315, Length=267, Percent_Identity=28.4644194756554, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI298566325, Length=267, Percent_Identity=28.4644194756554, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4885285, Length=267, Percent_Identity=28.4644194756554, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1786891, Length=275, Percent_Identity=25.8181818181818, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787878, Length=248, Percent_Identity=25.4032258064516, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787363, Length=308, Percent_Identity=29.2207792207792, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081733, Length=304, Percent_Identity=28.2894736842105, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790522, Length=300, Percent_Identity=28, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082230, Length=257, Percent_Identity=29.9610894941634, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 30866; Mature: 30735

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENLVLGIDLGGTAIKLGCCSPQGTCVRSITVPTPQPSTPEPVVDAISTAVHALDPDKT
CCCCEEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCC
LPVIGIGMPGPADNTGRIARVSINLDDWLDVPLAEWIEDKTGRPTTIANDANCAGLGEAL
CCEEEECCCCCCCCCCCEEEEEECCHHCCCCCHHHHHHCCCCCCCEEECCCCCCHHHHHH
YGAGQSFQNLIMLTLGTGVGGAIIMNGELYTGRDGAAGELGLITLWPDGPPCNSGNNGSL
HHCCCCCCEEEEEEECCCCCCEEEECCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCH
EQFASVRAIRRDHQCEPHELAVREDESAIAFWQDYGRNLGAGLASLIYVLTPEAVILGGG
HHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHHHCCCHHHHHHHHHHHHCCCEEEEECC
IAASTELFLPWVQAEIERRVMPTSRENLVILPAALGNQAGMIGAAQLARQRFGY
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TENLVLGIDLGGTAIKLGCCSPQGTCVRSITVPTPQPSTPEPVVDAISTAVHALDPDKT
CCCEEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCC
LPVIGIGMPGPADNTGRIARVSINLDDWLDVPLAEWIEDKTGRPTTIANDANCAGLGEAL
CCEEEECCCCCCCCCCCEEEEEECCHHCCCCCHHHHHHCCCCCCCEEECCCCCCHHHHHH
YGAGQSFQNLIMLTLGTGVGGAIIMNGELYTGRDGAAGELGLITLWPDGPPCNSGNNGSL
HHCCCCCCEEEEEEECCCCCCEEEECCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCH
EQFASVRAIRRDHQCEPHELAVREDESAIAFWQDYGRNLGAGLASLIYVLTPEAVILGGG
HHHHHHHHHHHHCCCCCCCEEEECCCCEEHHHHHHCCCHHHHHHHHHHHHCCCEEEEECC
IAASTELFLPWVQAEIERRVMPTSRENLVILPAALGNQAGMIGAAQLARQRFGY
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]