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The map label for this gene is coaE [H]

Identifier: 158335912

GI number: 158335912

Start: 2806009

End: 2806611

Strand: Reverse

Name: coaE [H]

Synonym: AM1_2770

Alternate gene names: 158335912

Gene position: 2806611-2806009 (Counterclockwise)

Preceding gene: 158335917

Following gene: 158335901

Centisome position: 43.15

GC content: 47.26

Gene sequence:

>603_bases
ATGGCTCGACGAATCATTGGGTTGACGGGAGGGATTGCGACGGGTAAGTCCAGCGTTGCAGCTTATCTAGAGTCGCAATA
TAAGCTACCTATCTTGGATGCCGATATCTATGCCCGTGATGCTGTGAAACCGGGGTCGGTAGCATTAGCCAGTATTGCCC
AACGCTATGGCGCAGAGATTCTGCTAGCAGACGGCAATCTGGATCGGAAACAGCTAGGTAATATTGTCTTTAATGATGAG
TCTGAACGCACTTGGCTGGAAGGCCAAATTCATCCTTATGTGCGAGAGCAAATTCTGGCTGCTCAACGACAACTCACGGA
TCCGATAGTGGTGGCAGTGGTGCCATTGCTGTTTGAAGCAAAAATGACGGATTTAGCTACAGAAATTTGGGTGGTGGTTT
GTACGGATGAGCAGCAGTGTCAGCGGTTGATGCGACGGGACTCGATTTCTAGATCACAAGCGAAAACCAGAATTGCTAGC
CAAATGCCTGTAATTGAAAAAGCTCACCGGGCTACAGTCGTGATTGATAATAACTCTGATCTAACTCGCCTATATAACCA
AGTTGATCAGGCTATGAATGTTGCATCAACTCCTCAAACCTAA

Upstream 100 bases:

>100_bases
ATGAATTTTTCAATGGGGTCTGGTTTTGTACTAGGACCTAATCAACGCCTAAAGTGGGGGGCTAAGATCTAGCAAGCAGT
CTGTTGGCAAAGCGAAAAAA

Downstream 100 bases:

>100_bases
CGCTGGTGAAGCCTCAAATAGTATGGACAAATAGATGTACACTGGGTTTCTTCAATTGATTATGGAAGAATAAGCTCAGC
TATATTTTCGCTTAGAGGTG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MARRIIGLTGGIATGKSSVAAYLESQYKLPILDADIYARDAVKPGSVALASIAQRYGAEILLADGNLDRKQLGNIVFNDE
SERTWLEGQIHPYVREQILAAQRQLTDPIVVAVVPLLFEAKMTDLATEIWVVVCTDEQQCQRLMRRDSISRSQAKTRIAS
QMPVIEKAHRATVVIDNNSDLTRLYNQVDQAMNVASTPQT

Sequences:

>Translated_200_residues
MARRIIGLTGGIATGKSSVAAYLESQYKLPILDADIYARDAVKPGSVALASIAQRYGAEILLADGNLDRKQLGNIVFNDE
SERTWLEGQIHPYVREQILAAQRQLTDPIVVAVVPLLFEAKMTDLATEIWVVVCTDEQQCQRLMRRDSISRSQAKTRIAS
QMPVIEKAHRATVVIDNNSDLTRLYNQVDQAMNVASTPQT
>Mature_199_residues
ARRIIGLTGGIATGKSSVAAYLESQYKLPILDADIYARDAVKPGSVALASIAQRYGAEILLADGNLDRKQLGNIVFNDES
ERTWLEGQIHPYVREQILAAQRQLTDPIVVAVVPLLFEAKMTDLATEIWVVVCTDEQQCQRLMRRDSISRSQAKTRIASQ
MPVIEKAHRATVVIDNNSDLTRLYNQVDQAMNVASTPQT

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=37.2222222222222, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=37.2222222222222, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI110227607, Length=174, Percent_Identity=30.4597701149425, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI110227605, Length=174, Percent_Identity=30.4597701149425, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227603, Length=174, Percent_Identity=30.4597701149425, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227601, Length=174, Percent_Identity=30.4597701149425, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI205277394, Length=174, Percent_Identity=30.4597701149425, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786292, Length=190, Percent_Identity=37.3684210526316, Blast_Score=120, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=35.2331606217617, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=29.7872340425532, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=39.0862944162437, Blast_Score=126, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24644728, Length=181, Percent_Identity=35.9116022099448, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658602, Length=192, Percent_Identity=30.7291666666667, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22168; Mature: 22036

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRIIGLTGGIATGKSSVAAYLESQYKLPILDADIYARDAVKPGSVALASIAQRYGAEI
CCCEEEEECCCCCCCHHHHHHHHHCCCCCCEECCCHHHHCCCCCCHHHHHHHHHHHCCEE
LLADGNLDRKQLGNIVFNDESERTWLEGQIHPYVREQILAAQRQLTDPIVVAVVPLLFEA
EEECCCCCHHHHCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KMTDLATEIWVVVCTDEQQCQRLMRRDSISRSQAKTRIASQMPVIEKAHRATVVIDNNSD
HHHHHHHEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCH
LTRLYNQVDQAMNVASTPQT
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ARRIIGLTGGIATGKSSVAAYLESQYKLPILDADIYARDAVKPGSVALASIAQRYGAEI
CCEEEEECCCCCCCHHHHHHHHHCCCCCCEECCCHHHHCCCCCCHHHHHHHHHHHCCEE
LLADGNLDRKQLGNIVFNDESERTWLEGQIHPYVREQILAAQRQLTDPIVVAVVPLLFEA
EEECCCCCHHHHCCEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KMTDLATEIWVVVCTDEQQCQRLMRRDSISRSQAKTRIASQMPVIEKAHRATVVIDNNSD
HHHHHHHEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCCEEEEEECCCH
LTRLYNQVDQAMNVASTPQT
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA