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The map label for this gene is umuC [H]

Identifier: 158335679

GI number: 158335679

Start: 2563279

End: 2564487

Strand: Direct

Name: umuC [H]

Synonym: AM1_2529

Alternate gene names: 158335679

Gene position: 2563279-2564487 (Clockwise)

Preceding gene: 158335678

Following gene: 158335681

Centisome position: 39.41

GC content: 52.52

Gene sequence:

>1209_bases
ATGGCGCTCAATCCCCACTTGCAACATAAGCCGGTTGTGATCGCTTCCAATAATGATGGGGTCGTTGTGACCGGCAATGC
TGCGGCGAAAGCCTTAGGCTTAGGCATGGGGGTGCCGCTGTTCAAGGCCCAAGATCTGATTAAAAAGCATGACGTACGAG
TCTTTAGCTCCAACTACGCGTTGTATGGTGACCTCTCCCAGCGGGTGATGGCAGTCTTGGAGCAGCACACACCTGAACAA
GAAATCTACTCCATTGATGAGTGCTTTATCCGTATGCCGGAATTTGCTGAGGCCACGACCTATGCCCGCAACATCAAAGA
GACGGTGAAAAAATGGACGGGGATTCCAGTTTCGATGGGGATGGCCACGTCCAAAACGTTAGCGAAAATTGCCAACCACG
TTGCTAAAAAACAGAAGGGATATGATGGCGTCTTTGATCTGTCCACGGCCCGCAATGCGGAAGGGATTCTGGCCACCTTT
CCTGTGAAAGAGATTTGGGGAATTGGACGGCAATACAATAAGTGGCTACTCAGCCAGGGCATTGAAACGGCAAAGGAACT
GCGAGATGCCAATGAAGGGATGATCCGTCAGAAAATGGGGGTGGTCGGTGTGCGGATAATTCATGAGCTTCAGGGAATTT
CTTGTCTGCCCCTAGAGCTGGTGGCCAAGCCCAAAAAAGAAATTTGTGTGTCTCGCTCCTTTGGTCAGCCCGTCACAGAG
TTGGCGGATTTGCAAGATGCGATCGCAGCCTACGCATCAAGAGCGGCAGAGAAGCTGCGCCAGGAACAGCAGGTGGCAGA
GGCCATGGTTGTATTCGCCCGCACCAGCCCTTTTAAGTCAGGATATTTTCGCCAATCCGCAACAGTGCAGTTCCCTATTG
CCACTAGCTATACGCCCGCCATAGTCGAAGCGGCCCGCAAAGCCATGGAGCGACTCTACGAACCGGACCGGGAATTTCAG
AAGGCAGGTGTGCTGATGGTGGGTCTTTGTTCTGAAACGACTATCCAAGGGCATCTCTGGGAGAAAGATGAGGGTTGGGA
GAAACGAAAGAGACTGATGTCGATTATGGATGAGGTGAATACTCGGTTTGGCCGAGGCACGATCGGCATTGCAGCGTCGG
GGGCAAAGCAGACCTGGAAAATGCAGTCAAAGTGGCGATCGCCGAGGTATACAACCTGCTGGGCAGAGTTACCTGTGGCG
AGTTGTTGA

Upstream 100 bases:

>100_bases
AGGTGTGGGGTGTGGTCACCTATGTGGTGCATGGGTTGCAGGTTTGAAACAGCGTCTAATCGGGCTGTGTGACTGCAACT
CGTTCTATGCCTCCTGTGAA

Downstream 100 bases:

>100_bases
AGGAGATAGCCTCAGGCTAGTGGCTTGCAGTTTCACTCCCCTCGATTAGATAGGTGCCAAACCCCAAAGAAGTTCAAGGT
GTTTTCGCTGATTGGGTTCT

Product: DNA polymerase V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MALNPHLQHKPVVIASNNDGVVVTGNAAAKALGLGMGVPLFKAQDLIKKHDVRVFSSNYALYGDLSQRVMAVLEQHTPEQ
EIYSIDECFIRMPEFAEATTYARNIKETVKKWTGIPVSMGMATSKTLAKIANHVAKKQKGYDGVFDLSTARNAEGILATF
PVKEIWGIGRQYNKWLLSQGIETAKELRDANEGMIRQKMGVVGVRIIHELQGISCLPLELVAKPKKEICVSRSFGQPVTE
LADLQDAIAAYASRAAEKLRQEQQVAEAMVVFARTSPFKSGYFRQSATVQFPIATSYTPAIVEAARKAMERLYEPDREFQ
KAGVLMVGLCSETTIQGHLWEKDEGWEKRKRLMSIMDEVNTRFGRGTIGIAASGAKQTWKMQSKWRSPRYTTCWAELPVA
SC

Sequences:

>Translated_402_residues
MALNPHLQHKPVVIASNNDGVVVTGNAAAKALGLGMGVPLFKAQDLIKKHDVRVFSSNYALYGDLSQRVMAVLEQHTPEQ
EIYSIDECFIRMPEFAEATTYARNIKETVKKWTGIPVSMGMATSKTLAKIANHVAKKQKGYDGVFDLSTARNAEGILATF
PVKEIWGIGRQYNKWLLSQGIETAKELRDANEGMIRQKMGVVGVRIIHELQGISCLPLELVAKPKKEICVSRSFGQPVTE
LADLQDAIAAYASRAAEKLRQEQQVAEAMVVFARTSPFKSGYFRQSATVQFPIATSYTPAIVEAARKAMERLYEPDREFQ
KAGVLMVGLCSETTIQGHLWEKDEGWEKRKRLMSIMDEVNTRFGRGTIGIAASGAKQTWKMQSKWRSPRYTTCWAELPVA
SC
>Mature_401_residues
ALNPHLQHKPVVIASNNDGVVVTGNAAAKALGLGMGVPLFKAQDLIKKHDVRVFSSNYALYGDLSQRVMAVLEQHTPEQE
IYSIDECFIRMPEFAEATTYARNIKETVKKWTGIPVSMGMATSKTLAKIANHVAKKQKGYDGVFDLSTARNAEGILATFP
VKEIWGIGRQYNKWLLSQGIETAKELRDANEGMIRQKMGVVGVRIIHELQGISCLPLELVAKPKKEICVSRSFGQPVTEL
ADLQDAIAAYASRAAEKLRQEQQVAEAMVVFARTSPFKSGYFRQSATVQFPIATSYTPAIVEAARKAMERLYEPDREFQK
AGVLMVGLCSETTIQGHLWEKDEGWEKRKRLMSIMDEVNTRFGRGTIGIAASGAKQTWKMQSKWRSPRYTTCWAELPVAS
C

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:
GO:0003684: DNA polymerase V, putative
GO:0003887: DNA polymerase V, putative
GO:0006281: DNA polymerase V, putative

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=401, Percent_Identity=41.645885286783, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1786425, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 44721; Mature: 44590

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNPHLQHKPVVIASNNDGVVVTGNAAAKALGLGMGVPLFKAQDLIKKHDVRVFSSNYA
CCCCCCCCCCCEEEEECCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCEE
LYGDLSQRVMAVLEQHTPEQEIYSIDECFIRMPEFAEATTYARNIKETVKKWTGIPVSMG
EECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEECC
MATSKTLAKIANHVAKKQKGYDGVFDLSTARNAEGILATFPVKEIWGIGRQYNKWLLSQG
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHH
IETAKELRDANEGMIRQKMGVVGVRIIHELQGISCLPLELVAKPKKEICVSRSFGQPVTE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHCCCCCHHHH
LADLQDAIAAYASRAAEKLRQEQQVAEAMVVFARTSPFKSGYFRQSATVQFPIATSYTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHH
IVEAARKAMERLYEPDREFQKAGVLMVGLCSETTIQGHLWEKDEGWEKRKRLMSIMDEVN
HHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCEECCEECCCCCCHHHHHHHHHHHHHHH
TRFGRGTIGIAASGAKQTWKMQSKWRSPRYTTCWAELPVASC
HHCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEHCCCCCCCC
>Mature Secondary Structure 
ALNPHLQHKPVVIASNNDGVVVTGNAAAKALGLGMGVPLFKAQDLIKKHDVRVFSSNYA
CCCCCCCCCCEEEEECCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCEE
LYGDLSQRVMAVLEQHTPEQEIYSIDECFIRMPEFAEATTYARNIKETVKKWTGIPVSMG
EECHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEECC
MATSKTLAKIANHVAKKQKGYDGVFDLSTARNAEGILATFPVKEIWGIGRQYNKWLLSQG
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHHHHHCCHHHHHHHHHHH
IETAKELRDANEGMIRQKMGVVGVRIIHELQGISCLPLELVAKPKKEICVSRSFGQPVTE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHCCCCCHHHH
LADLQDAIAAYASRAAEKLRQEQQVAEAMVVFARTSPFKSGYFRQSATVQFPIATSYTPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHH
IVEAARKAMERLYEPDREFQKAGVLMVGLCSETTIQGHLWEKDEGWEKRKRLMSIMDEVN
HHHHHHHHHHHHHCCCHHHHHCCEEEEEECCCCEECCEECCCCCCHHHHHHHHHHHHHHH
TRFGRGTIGIAASGAKQTWKMQSKWRSPRYTTCWAELPVASC
HHCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]