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The map label for this gene is rfc

Identifier: 158335371

GI number: 158335371

Start: 2222348

End: 2223736

Strand: Reverse

Name: rfc

Synonym: AM1_2216

Alternate gene names: NA

Gene position: 2223736-2222348 (Counterclockwise)

Preceding gene: 158335372

Following gene: 158335370

Centisome position: 34.19

GC content: 52.63

Gene sequence:

>1389_bases
ATGCATACCATTTGGCAGACATTGACCTTGAACAACATCCAATCCCTGCAATGGCGACAAGGCAGTCTGTTCTGGCGACT
GCTTGCCTTCCTTCGCCAGTGGCGGCAGGGGAGTTGGCTGCTGAACTGGCACCAGGAAATTGGTGCAGTCTTGCTGACGG
CGGTTTTTACCTTGGCTCCCTTTGTCCCTAATAGCCTGACGGGATTATTGGCAATGGCTTGTGGCTGTTATTGGCTGTTG
TTGACCCTTTCGGATGACCTGAAACCCCATCGATTTTCCCCGATTTATCTACTCGTGTTTTTGTTTTGGGGGATTACGGT
GATGGCTACAGCCCTATCGCCGGTGAAGTTGGCAGCGGTCTCTGGGTTGGTCAAAATGACCCTGTATGTATTTGTCTTTG
TTCTGGCAGAGCGGGTGGTGCGGTCGCCTCGACTACGCTCCTGGCTGATCGCCGTCTATCTGCATACAGCGATCATTGTG
TCTATTTATGGGGTGCGGCAAAAATTCTTTGGGGCAGAGGCCTTAGCTACTTGGGTAGATCCCAATTCCACCACCGCCGA
TGAGGTCAGAGTCTACAGCTATTTGGGCAATCCCAACCTGCTGGCAGCCTATATTCTGCCCGCCATCCTCTTTAGCATCT
GTGCCGTGGTGGCTTGGCAGCGTTGGGGTGCGAAGCTCTTGGCCGGGACGATGCTGCTGGTTCACTGTGCCTGTATGTAC
TGGACGGGCTGCCGAGGGGCTTGGATTGGTTTAGTCCTGGCGATTTTTGTGATGGCCATGATGGTGCTCTATTGGATACT
GCCCCGCTTACCGCAGTTGTGGCAGATTTGGGTATTTCCCCTCACCATTGGCACGATTGTGGGCGCAGTCGCCTTAGGGA
TTTTATTTGTGGCTCCTCTCCGTAACCGAGCCTTGAGCGCCTTCTCCGGTCATGAAGATAGTAGCAATAGCTTTCGACTG
AATGTCTGGGCCGGGGTGCAGGATATGATCCGAAAACGTCCCGTGTTGGGGATTGGCCCGGGTAATGTGGCCTTTAACCA
GATTTACCCCCTATTTCAACGACCCAATTACACTGCCCTGAGTGCCTATTCCATTTATTTAGAAACCTTGGTGGAGACCG
GGGTGGTTGGGTTTGCCAGTTTAATGTGGCTTCTCGCCCTGATTTTTCAGCAAACCTGGGTGCAGTTTCACAAGCTACGT
CAGCTCCAAAGCCAGGATGTTTGGTGGTTAGTGGGTGCGATCGCATCCATCATCGGTATGTTAATGCACGGGTTTGTGGA
TACCGTTTGGTATCGCCCTGAAATCAATACCCTGTGGTGGTTAACGGTAGCCATCGTCGCCAGCTATTACCGTCAAACCA
CAGCGGCTGATACCGCCGTATCGCTCTAA

Upstream 100 bases:

>100_bases
TCGAAAAATATGTCAGCCGACTTTTTAGTAAAACGGGCACCAATAGCCGGACAGAACTGGTACGCTTTGCCTTGGAGAAC
GGTCTGACACAGTAACTCTT

Downstream 100 bases:

>100_bases
GGGAAGGGCGAATCACTTGCCCATCAGAAACTATTTAGATTTCTGGGGCGTCAGAGGATGTACCAATCGGTTGTTGAATC
TCTCTGAACTCCTTGTAAGG

Product: O-antigen polymerase

Products: NA

Alternate protein names: Bicarbonate Transporter; Inorganic Carbon Transporter; O-Antigen Polymerase Family; Heptosyltransferase Family; ExoQ Family Exopolysaccharide Biosynthesis Membrane Protein; Related Polysaccharide Transport Proteins; IctB Family Bicarbonate Transporter; O-Antigen Polymerase Superfamily; Integral Membrane Protein; Bicarbonate Transporter ICT Family Protein; Exopolysaccharide Biosynthesis Family Protein

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MHTIWQTLTLNNIQSLQWRQGSLFWRLLAFLRQWRQGSWLLNWHQEIGAVLLTAVFTLAPFVPNSLTGLLAMACGCYWLL
LTLSDDLKPHRFSPIYLLVFLFWGITVMATALSPVKLAAVSGLVKMTLYVFVFVLAERVVRSPRLRSWLIAVYLHTAIIV
SIYGVRQKFFGAEALATWVDPNSTTADEVRVYSYLGNPNLLAAYILPAILFSICAVVAWQRWGAKLLAGTMLLVHCACMY
WTGCRGAWIGLVLAIFVMAMMVLYWILPRLPQLWQIWVFPLTIGTIVGAVALGILFVAPLRNRALSAFSGHEDSSNSFRL
NVWAGVQDMIRKRPVLGIGPGNVAFNQIYPLFQRPNYTALSAYSIYLETLVETGVVGFASLMWLLALIFQQTWVQFHKLR
QLQSQDVWWLVGAIASIIGMLMHGFVDTVWYRPEINTLWWLTVAIVASYYRQTTAADTAVSL

Sequences:

>Translated_462_residues
MHTIWQTLTLNNIQSLQWRQGSLFWRLLAFLRQWRQGSWLLNWHQEIGAVLLTAVFTLAPFVPNSLTGLLAMACGCYWLL
LTLSDDLKPHRFSPIYLLVFLFWGITVMATALSPVKLAAVSGLVKMTLYVFVFVLAERVVRSPRLRSWLIAVYLHTAIIV
SIYGVRQKFFGAEALATWVDPNSTTADEVRVYSYLGNPNLLAAYILPAILFSICAVVAWQRWGAKLLAGTMLLVHCACMY
WTGCRGAWIGLVLAIFVMAMMVLYWILPRLPQLWQIWVFPLTIGTIVGAVALGILFVAPLRNRALSAFSGHEDSSNSFRL
NVWAGVQDMIRKRPVLGIGPGNVAFNQIYPLFQRPNYTALSAYSIYLETLVETGVVGFASLMWLLALIFQQTWVQFHKLR
QLQSQDVWWLVGAIASIIGMLMHGFVDTVWYRPEINTLWWLTVAIVASYYRQTTAADTAVSL
>Mature_462_residues
MHTIWQTLTLNNIQSLQWRQGSLFWRLLAFLRQWRQGSWLLNWHQEIGAVLLTAVFTLAPFVPNSLTGLLAMACGCYWLL
LTLSDDLKPHRFSPIYLLVFLFWGITVMATALSPVKLAAVSGLVKMTLYVFVFVLAERVVRSPRLRSWLIAVYLHTAIIV
SIYGVRQKFFGAEALATWVDPNSTTADEVRVYSYLGNPNLLAAYILPAILFSICAVVAWQRWGAKLLAGTMLLVHCACMY
WTGCRGAWIGLVLAIFVMAMMVLYWILPRLPQLWQIWVFPLTIGTIVGAVALGILFVAPLRNRALSAFSGHEDSSNSFRL
NVWAGVQDMIRKRPVLGIGPGNVAFNQIYPLFQRPNYTALSAYSIYLETLVETGVVGFASLMWLLALIFQQTWVQFHKLR
QLQSQDVWWLVGAIASIIGMLMHGFVDTVWYRPEINTLWWLTVAIVASYYRQTTAADTAVSL

Specific function: Unknown

COG id: COG3307

COG function: function code M; Lipid A core - O-antigen ligase and related enzymes

Gene ontology:
GO:0005488: O-Antigen polymerase, putative

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52263; Mature: 52263

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTIWQTLTLNNIQSLQWRQGSLFWRLLAFLRQWRQGSWLLNWHQEIGAVLLTAVFTLAP
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHC
FVPNSLTGLLAMACGCYWLLLTLSDDLKPHRFSPIYLLVFLFWGITVMATALSPVKLAAV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
SGLVKMTLYVFVFVLAERVVRSPRLRSWLIAVYLHTAIIVSIYGVRQKFFGAEALATWVD
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCC
PNSTTADEVRVYSYLGNPNLLAAYILPAILFSICAVVAWQRWGAKLLAGTMLLVHCACMY
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTGCRGAWIGLVLAIFVMAMMVLYWILPRLPQLWQIWVFPLTIGTIVGAVALGILFVAPL
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNRALSAFSGHEDSSNSFRLNVWAGVQDMIRKRPVLGIGPGNVAFNQIYPLFQRPNYTAL
HHHHHHHHCCCCCCCCCEEEEEECCHHHHHHCCCCEEECCCCHHHHHHHHHHCCCCCCHH
SAYSIYLETLVETGVVGFASLMWLLALIFQQTWVQFHKLRQLQSQDVWWLVGAIASIIGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LMHGFVDTVWYRPEINTLWWLTVAIVASYYRQTTAADTAVSL
HHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA