Click here to switch to the map view.

The map label for this gene is kdsC [H]

Identifier: 158335351

GI number: 158335351

Start: 2199265

End: 2199777

Strand: Direct

Name: kdsC [H]

Synonym: AM1_2196

Alternate gene names: 158335351

Gene position: 2199265-2199777 (Clockwise)

Preceding gene: 158335350

Following gene: 158335352

Centisome position: 33.82

GC content: 49.71

Gene sequence:

>513_bases
ATGAGTATCTCCCCAGACCTACAATCTCGGCTCGCCAATGTTAAGCTTTTGGCCTTAGATGTGGATGGCGTCTTAACGGA
CGGCGGGCTGTACTACACCGAAACCGGCACCGAGCTGAAAAAGTTTAATGTCAAAGACGGTCAAGGCTTAAAGCTGCTGA
TGCAGTCAGGGGTTGACGTCGCCATTATTACAGCCAGCGATTCCCCCGTAACGCGGCATCGAGCCAAAAAGCTCGGCATT
CAGCATGTCTTTCTTGGGGTTGAAGAGAAGCTCTCGGTGCTCAAATCCCTTTGCCAAACTCTCAATATTGAGCTGTCTCA
AGTGGCCTATGCAGGGGATGATGTCAATGATGTGCCCATCTTGCAAAATATTGGCTGTCCATTCACCGTGAATGATGCCA
TGCCGACTAACCGAGGCGCTGCCATTTACATTACTCATAAAAACGGCGGGTGTGGCGCAGTACGAGAACTTTGTGATTTA
CTGATTCAAAGTCAGGCCGGTTCTTCATCCTAG

Upstream 100 bases:

>100_bases
GCGATGGTCCTAATATGATCCCGCTCCATCAGCTCGAAGATGTGTTGCGGCCCATCCTTGAGGTGCATAAAATCATGAAC
TCAACTCCCGTATTAGCCTG

Downstream 100 bases:

>100_bases
TTCCTGACAAGGATCTGCCAAAATGCAACAAAAGCTAAAACTCCGGTCGCGTCAGGATATTGTCCCCCTGGAAAAAGCGG
TTCTGGGACAATACTATTTT

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSISPDLQSRLANVKLLALDVDGVLTDGGLYYTETGTELKKFNVKDGQGLKLLMQSGVDVAIITASDSPVTRHRAKKLGI
QHVFLGVEEKLSVLKSLCQTLNIELSQVAYAGDDVNDVPILQNIGCPFTVNDAMPTNRGAAIYITHKNGGCGAVRELCDL
LIQSQAGSSS

Sequences:

>Translated_170_residues
MSISPDLQSRLANVKLLALDVDGVLTDGGLYYTETGTELKKFNVKDGQGLKLLMQSGVDVAIITASDSPVTRHRAKKLGI
QHVFLGVEEKLSVLKSLCQTLNIELSQVAYAGDDVNDVPILQNIGCPFTVNDAMPTNRGAAIYITHKNGGCGAVRELCDL
LIQSQAGSSS
>Mature_169_residues
SISPDLQSRLANVKLLALDVDGVLTDGGLYYTETGTELKKFNVKDGQGLKLLMQSGVDVAIITASDSPVTRHRAKKLGIQ
HVFLGVEEKLSVLKSLCQTLNIELSQVAYAGDDVNDVPILQNIGCPFTVNDAMPTNRGAAIYITHKNGGCGAVRELCDLL
IQSQAGSSS

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI2367202, Length=163, Percent_Identity=42.9447852760736, Blast_Score=136, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18117; Mature: 17986

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISPDLQSRLANVKLLALDVDGVLTDGGLYYTETGTELKKFNVKDGQGLKLLMQSGVDV
CCCCHHHHHHHCCEEEEEEECCCEEECCCEEEECCCCCEEEECCCCCCCHHHHHHCCCCE
AIITASDSPVTRHRAKKLGIQHVFLGVEEKLSVLKSLCQTLNIELSQVAYAGDDVNDVPI
EEEEECCCCHHHHHHHHHCHHHEEECHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCH
LQNIGCPFTVNDAMPTNRGAAIYITHKNGGCGAVRELCDLLIQSQAGSSS
HHHCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SISPDLQSRLANVKLLALDVDGVLTDGGLYYTETGTELKKFNVKDGQGLKLLMQSGVDV
CCCHHHHHHHCCEEEEEEECCCEEECCCEEEECCCCCEEEECCCCCCCHHHHHHCCCCE
AIITASDSPVTRHRAKKLGIQHVFLGVEEKLSVLKSLCQTLNIELSQVAYAGDDVNDVPI
EEEEECCCCHHHHHHHHHCHHHEEECHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCH
LQNIGCPFTVNDAMPTNRGAAIYITHKNGGCGAVRELCDLLIQSQAGSSS
HHHCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]