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The map label for this gene is 158335318

Identifier: 158335318

GI number: 158335318

Start: 2157378

End: 2157941

Strand: Direct

Name: 158335318

Synonym: AM1_2162

Alternate gene names: NA

Gene position: 2157378-2157941 (Clockwise)

Preceding gene: 158335317

Following gene: 158335319

Centisome position: 33.17

GC content: 50.89

Gene sequence:

>564_bases
ATGAGAGATCAGCTCAAAACCCAACTGCAAATTTTAGGACTCTGTGCAGTCACACTGTGGAGCATCCAGCTTATCAATTG
GTTGACGGGTGATTTACTGATTCAGTTTGGTATTCAACCCCGTAGCCTTGTTGGCCTACGGGGTATTCTATTTGCGCCTT
TTCTACACGGCAACTTCAGACATCTAATCGCGAATACAGCTCCTTTTCTGGTCTTGGGCGGATTGGTGATGGTCCGCCGG
ATTATGGACTTTTTCTCCGTCAGTCTGATTGTGATGGTGGTGGGTGGTCTAGGCACCTGGCTGATTGGCGGCAGTGATAC
CCTCCATATTGGGGCCAGTGGCTTGGTCTTCGGTTACCTGGGCTATCTGCTATTTCGGGGATACTTTGAGCGCAGTTGGC
CGGCCATTACCCTGTCGGTGTTTGTGGCCATTGTCTATGGCAGTATGCTGTTTGGCTTGTTACCGACCATGCCCCATATT
TCTTGGGAAGGCCACCTGTTTGGATTTATCGGGGGCGGACTAGCGGCGAAATGGCTGACCGCAAAACCCAAATCAGCAGC
CTAA

Upstream 100 bases:

>100_bases
AATTTGCTGAAGTGGTAGCAGGCCGTCTTATCTTGGAGTCAAGAGTGGCGATCTCACTGCTGAGCTGATTATGCTTGAGA
TGTAGCGCATCGCAACCTGC

Downstream 100 bases:

>100_bases
TTGCCCCAAGAAGCTCACAAATAAGCGGTAGAATTATTAAGTAATTTTTCAAAATGTTACTATGCCTCGCCGCGCTAATG
CTCCCAAACAAGAGAAGAAA

Product: rhomboid family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRDQLKTQLQILGLCAVTLWSIQLINWLTGDLLIQFGIQPRSLVGLRGILFAPFLHGNFRHLIANTAPFLVLGGLVMVRR
IMDFFSVSLIVMVVGGLGTWLIGGSDTLHIGASGLVFGYLGYLLFRGYFERSWPAITLSVFVAIVYGSMLFGLLPTMPHI
SWEGHLFGFIGGGLAAKWLTAKPKSAA

Sequences:

>Translated_187_residues
MRDQLKTQLQILGLCAVTLWSIQLINWLTGDLLIQFGIQPRSLVGLRGILFAPFLHGNFRHLIANTAPFLVLGGLVMVRR
IMDFFSVSLIVMVVGGLGTWLIGGSDTLHIGASGLVFGYLGYLLFRGYFERSWPAITLSVFVAIVYGSMLFGLLPTMPHI
SWEGHLFGFIGGGLAAKWLTAKPKSAA
>Mature_187_residues
MRDQLKTQLQILGLCAVTLWSIQLINWLTGDLLIQFGIQPRSLVGLRGILFAPFLHGNFRHLIANTAPFLVLGGLVMVRR
IMDFFSVSLIVMVVGGLGTWLIGGSDTLHIGASGLVFGYLGYLLFRGYFERSWPAITLSVFVAIVYGSMLFGLLPTMPHI
SWEGHLFGFIGGGLAAKWLTAKPKSAA

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 20451; Mature: 20451

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDQLKTQLQILGLCAVTLWSIQLINWLTGDLLIQFGIQPRSLVGLRGILFAPFLHGNFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
HLIANTAPFLVLGGLVMVRRIMDFFSVSLIVMVVGGLGTWLIGGSDTLHIGASGLVFGYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCHHHHHHHH
GYLLFRGYFERSWPAITLSVFVAIVYGSMLFGLLPTMPHISWEGHLFGFIGGGLAAKWLT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCHHHHHHHC
AKPKSAA
CCCCCCC
>Mature Secondary Structure
MRDQLKTQLQILGLCAVTLWSIQLINWLTGDLLIQFGIQPRSLVGLRGILFAPFLHGNFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHH
HLIANTAPFLVLGGLVMVRRIMDFFSVSLIVMVVGGLGTWLIGGSDTLHIGASGLVFGYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCHHHHHHHH
GYLLFRGYFERSWPAITLSVFVAIVYGSMLFGLLPTMPHISWEGHLFGFIGGGLAAKWLT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCHHHHHHHC
AKPKSAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]