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The map label for this gene is ilvH [H]

Identifier: 158335275

GI number: 158335275

Start: 2107307

End: 2107825

Strand: Direct

Name: ilvH [H]

Synonym: AM1_2118

Alternate gene names: 158335275

Gene position: 2107307-2107825 (Clockwise)

Preceding gene: 158335274

Following gene: 158335278

Centisome position: 32.4

GC content: 48.17

Gene sequence:

>519_bases
ATGAAACATACACTGTCCGTCTTAGTTGAAGACGAAGCTGGCGTTCTCACTCGCATCGCCGGACTTTTTGCCCGACGAGG
ATTTAACATCGAAAGTTTAGCCGTTGGACCTGCCGAGCAAATTGGGGTCTCTCGCATTACGATGGTCGTTCCCGGTGATA
ATCGCAGCATTGAGCAGCTCACCAAGCAGCTCTATAAGCTAATCAATGTTCTTAAGGTTCAGGATATTACTGAAGTCCCC
TGTGTGGAGCGGGAGCTGATGTTGATTAAAGTCAATGCCGCGGCGTCTCTACGCTCTGAGATTGTGGAAATTGTCCAAAT
CTTTCGTGCCAAAGTGGTGGATGTTTCTGAGGACGCTCTCACCATCGAGGTCTCAGGTGACCCAGGCAAGATGGTGGCAA
TTGTGCAAATGCTGAACAAGTTCGGCATTCAAGAAATTGCCCGAACTGGCAAGATTGCCTTAACCCGAGAATCACGCGTC
AATACTGAATATCTGAAATCTTTAGCAGCCAAGGTTTAG

Upstream 100 bases:

>100_bases
TTCCCTATCCAGCAGCCACAGCCAGAACAGTTGCACTGCGCCTAGATTTGGTTGCATAATCAGGCCATTACACCACCCCA
AGCTGGGGCTGAATCAAACC

Downstream 100 bases:

>100_bases
CAACTCAAAGATCTGCCAGCCTCAAAGGATTCAAGAGCAGTCTTAATAACTGCCGTCGTCATTCTCTGGTCCACCTGAAC
CCGGGCCTGGGTACTTGGGT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQIGVSRITMVVPGDNRSIEQLTKQLYKLINVLKVQDITEVP
CVERELMLIKVNAAASLRSEIVEIVQIFRAKVVDVSEDALTIEVSGDPGKMVAIVQMLNKFGIQEIARTGKIALTRESRV
NTEYLKSLAAKV

Sequences:

>Translated_172_residues
MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQIGVSRITMVVPGDNRSIEQLTKQLYKLINVLKVQDITEVP
CVERELMLIKVNAAASLRSEIVEIVQIFRAKVVDVSEDALTIEVSGDPGKMVAIVQMLNKFGIQEIARTGKIALTRESRV
NTEYLKSLAAKV
>Mature_172_residues
MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQIGVSRITMVVPGDNRSIEQLTKQLYKLINVLKVQDITEVP
CVERELMLIKVNAAASLRSEIVEIVQIFRAKVVDVSEDALTIEVSGDPGKMVAIVQMLNKFGIQEIARTGKIALTRESRV
NTEYLKSLAAKV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=161, Percent_Identity=39.7515527950311, Blast_Score=132, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=29.9019607843137, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18887; Mature: 18887

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQIGVSRITMVVPGDNRSIEQL
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHEECCCHHHCCCEEEEEEECCCCCCHHHH
TKQLYKLINVLKVQDITEVPCVERELMLIKVNAAASLRSEIVEIVQIFRAKVVDVSEDAL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEE
TIEVSGDPGKMVAIVQMLNKFGIQEIARTGKIALTRESRVNTEYLKSLAAKV
EEEECCCCCHHHHHHHHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKHTLSVLVEDEAGVLTRIAGLFARRGFNIESLAVGPAEQIGVSRITMVVPGDNRSIEQL
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHEECCCHHHCCCEEEEEEECCCCCCHHHH
TKQLYKLINVLKVQDITEVPCVERELMLIKVNAAASLRSEIVEIVQIFRAKVVDVSEDAL
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEE
TIEVSGDPGKMVAIVQMLNKFGIQEIARTGKIALTRESRVNTEYLKSLAAKV
EEEECCCCCHHHHHHHHHHHHCHHHHHHCCCEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]