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The map label for this gene is acoC [H]

Identifier: 158335274

GI number: 158335274

Start: 2106280

End: 2107251

Strand: Direct

Name: acoC [H]

Synonym: AM1_2117

Alternate gene names: 158335274

Gene position: 2106280-2107251 (Clockwise)

Preceding gene: 158335273

Following gene: 158335275

Centisome position: 32.39

GC content: 52.67

Gene sequence:

>972_bases
TTGAGTACATCCAGAACTTGGCAACAGCAAATCGGCCACCAGCGAGACTGGGCTTGGCGGGGATGGCAAATTCGCTATAC
CTTTATGCGCGGACAACAGGAGACAACGCAGCCCCCCATGCTGCTATTACATGGGTTCGGAGCTTCGATCGGCCATTGGC
GATTCAATATACCGGTGTTTGCCAAAGACCGAACCATCTATGCGCTAGATTTACTAGGATTTGGGGCATCCGAGAAAGTC
TCTACCGACTATTTAGTGACCCTATGGGTGGAACAGGTTCATGACTTTTGGCAGACCTATATCCGCACCCCAATGGTTTT
GGTGGGTAATTCTTTAGGATCCTTGGTCAGTCTTACGGCTGCAGCCCTTTACCCAGAGATGGTGGCGGGATTGGCCATGC
TAACCCTGCCGGATACATCGGTGTTGAAAAATCCTTCATGGGTCAAACCTGCGATCGCACCTTTGAAACTCGCCCTCAAT
CCCGTAGCCGCATTCGCCAAAGCCTTGTTCACTGCGCCCCCAATCTTCAACCCGTTTTTTCAATTCATTCGCCAGCCCAA
GATTATTCGTTCCTGGGTCAAGAAAGCCTATATCGATACCACGTCCGTTGAAGATGATCTCGTCGATATCCTTTCCAGCC
CTGCCTATGATCAGGGGGCCGCAGATGCCCTCCGAGCCATGGTCAACACTATGTCCAAGCCCCAAGTCCCTCAACATACG
GCTAAGGAGATGCTGCCTCAATTAACGATTCCGATTCTGTTGGTGTGGGGGCAGCAAGATGTCATGATCCCACCCAAATT
GGGACCGCTCTTTGCCCGCTGCAATCCTCGAATCCAGCTGGTCGAGTTAGCCCATGCGGGCCATTGCCCCCATGATGAAT
GTCCAGACCGACTCAACCCTATTCTTCTAGACTGGCTCGCCGCTCACTTCCCTATCCAGCAGCCACAGCCAGAACAGTTG
CACTGCGCCTAG

Upstream 100 bases:

>100_bases
CAGTTTTTAGATCGTTCTGATCCAGCTGCAGACAATAAACCGTCCTCTGCCCCATAGGGATATCACTAGAATTGAGTCGA
CAGTAGGGTAGGCAATCGGA

Downstream 100 bases:

>100_bases
ATTTGGTTGCATAATCAGGCCATTACACCACCCCAAGCTGGGGCTGAATCAAACCATGAAACATACACTGTCCGTCTTAG
TTGAAGACGAAGCTGGCGTT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSTSRTWQQQIGHQRDWAWRGWQIRYTFMRGQQETTQPPMLLLHGFGASIGHWRFNIPVFAKDRTIYALDLLGFGASEKV
STDYLVTLWVEQVHDFWQTYIRTPMVLVGNSLGSLVSLTAAALYPEMVAGLAMLTLPDTSVLKNPSWVKPAIAPLKLALN
PVAAFAKALFTAPPIFNPFFQFIRQPKIIRSWVKKAYIDTTSVEDDLVDILSSPAYDQGAADALRAMVNTMSKPQVPQHT
AKEMLPQLTIPILLVWGQQDVMIPPKLGPLFARCNPRIQLVELAHAGHCPHDECPDRLNPILLDWLAAHFPIQQPQPEQL
HCA

Sequences:

>Translated_323_residues
MSTSRTWQQQIGHQRDWAWRGWQIRYTFMRGQQETTQPPMLLLHGFGASIGHWRFNIPVFAKDRTIYALDLLGFGASEKV
STDYLVTLWVEQVHDFWQTYIRTPMVLVGNSLGSLVSLTAAALYPEMVAGLAMLTLPDTSVLKNPSWVKPAIAPLKLALN
PVAAFAKALFTAPPIFNPFFQFIRQPKIIRSWVKKAYIDTTSVEDDLVDILSSPAYDQGAADALRAMVNTMSKPQVPQHT
AKEMLPQLTIPILLVWGQQDVMIPPKLGPLFARCNPRIQLVELAHAGHCPHDECPDRLNPILLDWLAAHFPIQQPQPEQL
HCA
>Mature_322_residues
STSRTWQQQIGHQRDWAWRGWQIRYTFMRGQQETTQPPMLLLHGFGASIGHWRFNIPVFAKDRTIYALDLLGFGASEKVS
TDYLVTLWVEQVHDFWQTYIRTPMVLVGNSLGSLVSLTAAALYPEMVAGLAMLTLPDTSVLKNPSWVKPAIAPLKLALNP
VAAFAKALFTAPPIFNPFFQFIRQPKIIRSWVKKAYIDTTSVEDDLVDILSSPAYDQGAADALRAMVNTMSKPQVPQHTA
KEMLPQLTIPILLVWGQQDVMIPPKLGPLFARCNPRIQLVELAHAGHCPHDECPDRLNPILLDWLAAHFPIQQPQPEQLH
CA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=293, Percent_Identity=23.5494880546075, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI218777837, Length=284, Percent_Identity=23.2394366197183, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24586387, Length=289, Percent_Identity=27.681660899654, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586391, Length=289, Percent_Identity=27.681660899654, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586389, Length=289, Percent_Identity=27.681660899654, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586385, Length=288, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 36376; Mature: 36244

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSRTWQQQIGHQRDWAWRGWQIRYTFMRGQQETTQPPMLLLHGFGASIGHWRFNIPVF
CCCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEECEEE
AKDRTIYALDLLGFGASEKVSTDYLVTLWVEQVHDFWQTYIRTPMVLVGNSLGSLVSLTA
ECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHH
AALYPEMVAGLAMLTLPDTSVLKNPSWVKPAIAPLKLALNPVAAFAKALFTAPPIFNPFF
HHHHHHHHHCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QFIRQPKIIRSWVKKAYIDTTSVEDDLVDILSSPAYDQGAADALRAMVNTMSKPQVPQHT
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
AKEMLPQLTIPILLVWGQQDVMIPPKLGPLFARCNPRIQLVELAHAGHCPHDECPDRLNP
HHHHHHHHCEEEEEEECCCCEECCCCCCCHHHCCCCCEEEEEEHHCCCCCCCCCHHHCCH
ILLDWLAAHFPIQQPQPEQLHCA
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
STSRTWQQQIGHQRDWAWRGWQIRYTFMRGQQETTQPPMLLLHGFGASIGHWRFNIPVF
CCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEECEEE
AKDRTIYALDLLGFGASEKVSTDYLVTLWVEQVHDFWQTYIRTPMVLVGNSLGSLVSLTA
ECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHH
AALYPEMVAGLAMLTLPDTSVLKNPSWVKPAIAPLKLALNPVAAFAKALFTAPPIFNPFF
HHHHHHHHHCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QFIRQPKIIRSWVKKAYIDTTSVEDDLVDILSSPAYDQGAADALRAMVNTMSKPQVPQHT
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHH
AKEMLPQLTIPILLVWGQQDVMIPPKLGPLFARCNPRIQLVELAHAGHCPHDECPDRLNP
HHHHHHHHCEEEEEEECCCCEECCCCCCCHHHCCCCCEEEEEEHHCCCCCCCCCHHHCCH
ILLDWLAAHFPIQQPQPEQLHCA
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]