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The map label for this gene is phoB [H]

Identifier: 158334970

GI number: 158334970

Start: 1795689

End: 1796336

Strand: Direct

Name: phoB [H]

Synonym: AM1_1808

Alternate gene names: 158334970

Gene position: 1795689-1796336 (Clockwise)

Preceding gene: 158334969

Following gene: 158334976

Centisome position: 27.61

GC content: 46.76

Gene sequence:

>648_bases
ATGCAAGACGTTATCACAGCTGATCAAAATCAACTGCTACTCATTGATGATGATCCGAATCTGATTTTATTAGTGAAGGA
TTACCTAGAATTACGTGGGTATGAGGTGACAACGGCCAAGAATGGTCGGGAAGCCCTGCGTGTTCTAGAGAAGAGTATTC
CTAATCTAATCATCTGTGATGTGATGATGCCAGAGATGGACGGCTATGCGTTTGTCAAACGTGTTCGGGATAATCCTCAA
ACCAGCTATCTCCCCGTTCTCTTTTTGTCAGCTAAGGGACAAATTCAAGACCGGGTCACCGGACTCAACACCGGGGCTGA
TGTATATATGATTAAGCCCTTTGAACCCGATGAATTAGTGGCGCAAATCGAAGCATCCCTAAAGCAAGCCTCTCGAATGA
TGCAGAAACAAGCGAACTCCTTAGAAGGAGAGCTATCGGTTCAAGTCCCCTTTGATGTCGATTTAACCCCAACAGAGACA
AAAGTCATTCAGCTTGTTGCCAAAGGCATGTCCAACCGAGAGATCGCAGATGACCTGAGCGTTAGTCAACGCACGGTCGA
AAGCCACGTCAGCAATATGCTCGGAAAAACAGGCTTAAACAACCGTACAGAACTCGCTCGCTGGGCCATTGAGCAACGCA
TGGTCTAG

Upstream 100 bases:

>100_bases
GTAATAATACGGTATACATTAGCGGTACTCGGCAACTTTAACTACGGTGACAAGATTTCTGGGTAACGCTAAGCATAAAG
ACACGGGTGGCTTCTAGAGT

Downstream 100 bases:

>100_bases
GTACGGTTCCGAGATCCCTCAAGTGACAACAGCCACAACATCAAAGACAACACACCAACCTGCAATGCGAAGTTTGGCAG
TGTAGTAGCGATATCTTTCC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MQDVITADQNQLLLIDDDPNLILLVKDYLELRGYEVTTAKNGREALRVLEKSIPNLIICDVMMPEMDGYAFVKRVRDNPQ
TSYLPVLFLSAKGQIQDRVTGLNTGADVYMIKPFEPDELVAQIEASLKQASRMMQKQANSLEGELSVQVPFDVDLTPTET
KVIQLVAKGMSNREIADDLSVSQRTVESHVSNMLGKTGLNNRTELARWAIEQRMV

Sequences:

>Translated_215_residues
MQDVITADQNQLLLIDDDPNLILLVKDYLELRGYEVTTAKNGREALRVLEKSIPNLIICDVMMPEMDGYAFVKRVRDNPQ
TSYLPVLFLSAKGQIQDRVTGLNTGADVYMIKPFEPDELVAQIEASLKQASRMMQKQANSLEGELSVQVPFDVDLTPTET
KVIQLVAKGMSNREIADDLSVSQRTVESHVSNMLGKTGLNNRTELARWAIEQRMV
>Mature_215_residues
MQDVITADQNQLLLIDDDPNLILLVKDYLELRGYEVTTAKNGREALRVLEKSIPNLIICDVMMPEMDGYAFVKRVRDNPQ
TSYLPVLFLSAKGQIQDRVTGLNTGADVYMIKPFEPDELVAQIEASLKQASRMMQKQANSLEGELSVQVPFDVDLTPTET
KVIQLVAKGMSNREIADDLSVSQRTVESHVSNMLGKTGLNNRTELARWAIEQRMV

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=208, Percent_Identity=29.3269230769231, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1786599, Length=202, Percent_Identity=28.7128712871287, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1789809, Length=136, Percent_Identity=36.7647058823529, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367329, Length=222, Percent_Identity=36.4864864864865, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788550, Length=147, Percent_Identity=32.6530612244898, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI87082012, Length=119, Percent_Identity=37.8151260504202, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=36.5079365079365, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790552, Length=205, Percent_Identity=30.2439024390244, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787375, Length=161, Percent_Identity=32.9192546583851, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786747, Length=156, Percent_Identity=29.4871794871795, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=37.9032258064516, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788521, Length=209, Percent_Identity=29.6650717703349, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=30.3030303030303, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787473, Length=212, Percent_Identity=31.6037735849057, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790102, Length=199, Percent_Identity=30.1507537688442, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789402, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=121, Percent_Identity=32.2314049586777, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790860, Length=206, Percent_Identity=24.7572815533981, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=132, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790863, Length=110, Percent_Identity=30, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24140; Mature: 24140

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVITADQNQLLLIDDDPNLILLVKDYLELRGYEVTTAKNGREALRVLEKSIPNLIICD
CCCCEECCCCCEEEEECCCCEEEEEEHHHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEE
VMMPEMDGYAFVKRVRDNPQTSYLPVLFLSAKGQIQDRVTGLNTGADVYMIKPFEPDELV
EECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEECCCCHHHHH
AQIEASLKQASRMMQKQANSLEGELSVQVPFDVDLTPTETKVIQLVAKGMSNREIADDLS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
VSQRTVESHVSNMLGKTGLNNRTELARWAIEQRMV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDVITADQNQLLLIDDDPNLILLVKDYLELRGYEVTTAKNGREALRVLEKSIPNLIICD
CCCCEECCCCCEEEEECCCCEEEEEEHHHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEE
VMMPEMDGYAFVKRVRDNPQTSYLPVLFLSAKGQIQDRVTGLNTGADVYMIKPFEPDELV
EECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCEEEECCCCHHHHH
AQIEASLKQASRMMQKQANSLEGELSVQVPFDVDLTPTETKVIQLVAKGMSNREIADDLS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
VSQRTVESHVSNMLGKTGLNNRTELARWAIEQRMV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]