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The map label for this gene is fbp [H]

Identifier: 158334954

GI number: 158334954

Start: 1781977

End: 1782510

Strand: Direct

Name: fbp [H]

Synonym: AM1_1791

Alternate gene names: 158334954

Gene position: 1781977-1782510 (Clockwise)

Preceding gene: 158334953

Following gene: 158334964

Centisome position: 27.4

GC content: 48.31

Gene sequence:

>534_bases
TTGCGTAATATCTTAATCAGTTTCGGGATTCTCCTTGTTTGTAGCGCCGTTTTGGTCATTGCCCAAATCACGAACGGTAC
ACCCGAAGTATCCGCAGAACCCTTACAAACAGATAACCTGACAACCGTTGCTGCTATTTCTGTTGCCCAAACTCCCACAT
CTGACATGCATTCAACTGACACTGAAGATTCCGATTACACCACCACTGCATCTGGCTTGCAATATCGCGACTTAGTAGAA
GGCACAGGTGAGCAACCTATGCTAGGCCAAATGGTCGTCGTTCACTATACTGGCACCTTAACCGATGGGAGTAAATTCGA
TAGCTCTCGAGACCGCGGACAGCCATTCTCATTCCCCATTGGTAAGGGACGAGTTATCAAAGGTTGGGACGAAGGTGTTG
GCACCATGAAAGTAGGTGGTCGCCGAGAGCTAGTCATTCCCCCTGATTTGGGTTATGGCTCAAGAGGCGCCGGTGGTGTC
ATTCCTCCCAATGCCACCCTAGTTTTTGATGTTGAATTACTGAGAATTCAGTAG

Upstream 100 bases:

>100_bases
CGACAAGTGCGAGACTTAGAAAATAAGCTTTGGCGATAGCCTCCTCAATCAAAACCAACCCTTCAAAGCATCACCATCCT
AAAACGATCGGAGGAATACC

Downstream 100 bases:

>100_bases
CTAAAACCTTATAAAAAGCACAAATGCGCCCGATTTATCTATAGTTCGGGCGCATTTGTGCTTTTGGGCAATTAAATGGT
GTCAAGCCAGATGTTTTTAG

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRNILISFGILLVCSAVLVIAQITNGTPEVSAEPLQTDNLTTVAAISVAQTPTSDMHSTDTEDSDYTTTASGLQYRDLVE
GTGEQPMLGQMVVVHYTGTLTDGSKFDSSRDRGQPFSFPIGKGRVIKGWDEGVGTMKVGGRRELVIPPDLGYGSRGAGGV
IPPNATLVFDVELLRIQ

Sequences:

>Translated_177_residues
MRNILISFGILLVCSAVLVIAQITNGTPEVSAEPLQTDNLTTVAAISVAQTPTSDMHSTDTEDSDYTTTASGLQYRDLVE
GTGEQPMLGQMVVVHYTGTLTDGSKFDSSRDRGQPFSFPIGKGRVIKGWDEGVGTMKVGGRRELVIPPDLGYGSRGAGGV
IPPNATLVFDVELLRIQ
>Mature_177_residues
MRNILISFGILLVCSAVLVIAQITNGTPEVSAEPLQTDNLTTVAAISVAQTPTSDMHSTDTEDSDYTTTASGLQYRDLVE
GTGEQPMLGQMVVVHYTGTLTDGSKFDSSRDRGQPFSFPIGKGRVIKGWDEGVGTMKVGGRRELVIPPDLGYGSRGAGGV
IPPNATLVFDVELLRIQ

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=107, Percent_Identity=57.0093457943925, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI4503725, Length=107, Percent_Identity=57.0093457943925, Blast_Score=124, Evalue=4e-29,
Organism=Homo sapiens, GI4758380, Length=92, Percent_Identity=59.7826086956522, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI4503729, Length=99, Percent_Identity=57.5757575757576, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI224809329, Length=98, Percent_Identity=54.0816326530612, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI224809327, Length=98, Percent_Identity=54.0816326530612, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI4758384, Length=98, Percent_Identity=54.0816326530612, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI224809331, Length=98, Percent_Identity=54.0816326530612, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI206725530, Length=89, Percent_Identity=57.3033707865169, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI17149844, Length=89, Percent_Identity=57.3033707865169, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI17149842, Length=89, Percent_Identity=57.3033707865169, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI192448443, Length=89, Percent_Identity=52.8089887640449, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI33469985, Length=88, Percent_Identity=51.1363636363636, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI8923659, Length=92, Percent_Identity=47.8260869565217, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI4503727, Length=99, Percent_Identity=43.4343434343434, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI206725547, Length=100, Percent_Identity=43, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI31317231, Length=101, Percent_Identity=43.5643564356436, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI17149839, Length=51, Percent_Identity=60.7843137254902, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI150010552, Length=116, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI7706131, Length=105, Percent_Identity=37.1428571428571, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI87082390, Length=110, Percent_Identity=52.7272727272727, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=51.8181818181818, Blast_Score=100, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71993519, Length=104, Percent_Identity=58.6538461538462, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540882, Length=97, Percent_Identity=54.639175257732, Blast_Score=111, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17561782, Length=90, Percent_Identity=56.6666666666667, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561778, Length=98, Percent_Identity=43.8775510204082, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71993555, Length=64, Percent_Identity=56.25, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506169, Length=112, Percent_Identity=36.6071428571429, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17506167, Length=112, Percent_Identity=36.6071428571429, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324194, Length=92, Percent_Identity=57.6086956521739, Blast_Score=110, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320727, Length=107, Percent_Identity=54.2056074766355, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323482, Length=106, Percent_Identity=43.3962264150943, Blast_Score=85, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=106, Percent_Identity=42.4528301886792, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=60.7476635514019, Blast_Score=133, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281363946, Length=89, Percent_Identity=64.0449438202247, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17352457, Length=89, Percent_Identity=64.0449438202247, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24583150, Length=98, Percent_Identity=53.0612244897959, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24647110, Length=114, Percent_Identity=46.4912280701754, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356629, Length=103, Percent_Identity=54.3689320388349, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18829; Mature: 18829

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNILISFGILLVCSAVLVIAQITNGTPEVSAEPLQTDNLTTVAAISVAQTPTSDMHSTD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCC
TEDSDYTTTASGLQYRDLVEGTGEQPMLGQMVVVHYTGTLTDGSKFDSSRDRGQPFSFPI
CCCCCCEECCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
GKGRVIKGWDEGVGTMKVGGRRELVIPPDLGYGSRGAGGVIPPNATLVFDVELLRIQ
CCCCEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure
MRNILISFGILLVCSAVLVIAQITNGTPEVSAEPLQTDNLTTVAAISVAQTPTSDMHSTD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCC
TEDSDYTTTASGLQYRDLVEGTGEQPMLGQMVVVHYTGTLTDGSKFDSSRDRGQPFSFPI
CCCCCCEECCCCCCHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
GKGRVIKGWDEGVGTMKVGGRRELVIPPDLGYGSRGAGGVIPPNATLVFDVELLRIQ
CCCCEEECCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]