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The map label for this gene is crt [H]

Identifier: 158334786

GI number: 158334786

Start: 1590936

End: 1591772

Strand: Direct

Name: crt [H]

Synonym: AM1_1621

Alternate gene names: 158334786

Gene position: 1590936-1591772 (Clockwise)

Preceding gene: 158334784

Following gene: 158334787

Centisome position: 24.46

GC content: 53.64

Gene sequence:

>837_bases
ATGAGCTACACCACGTTCAACGTTGAAATCAAAAACGCCATCGCTTGGGTCACCTTCGACTACCCACCTGTTAATATTCA
GGGCCTGCCAATGCTGGCCGACCTCAATATGCTGGCCCAAAGGCTGGAAACGGATCGCACCATCAAAGTTGTCGTATTTC
AATCCGCCCATCCCGAGATTTTCGTGGCCCATGCCGACACGAATTTCCTCAAAGACATGTCTGCGATCGCAGTCTCTCGC
GACGAAGTCAAACTCCTGGATTTGCAGGTGGTGCTAGAGCGGATTAGCAAGCTGCCCCAGGCCACCATCGCCAAGATCGA
AGGCTTTGCCCGCGGCGGTGGTCATGAATTTGCCCTAGCCTGCGATATGCGATTTGCCGCCCGAGGGAAAGCCAAATTCA
TGCAGATGGAAGTTGCCATGGGCATTCTTCCGTGTGGCGGAGGCGCATCGCGGATGGCCCGTCAGATCGGGTTAGGGCGA
GCTCTGGAAATTATTTTAGGTGCAAAAGACTTTGATGCCGACCAGGCCGAAGCCTATGGCACCATCAACAAAGCCTTCGA
TCCAGAAGAGATTGGCCCATTTGTGGAAGCCTTGGCGAACCGGATCGCCCTTTGGCCCGCTGAATCGATCAACGCCTGCA
AACAAAGCGTCTACGCCTCCATCGACAAACCCATTGATGAAGCCCTGCAGGAAGAAGCCTATTGGCTGTATCAGGCCACG
AGCCAGACCCCGGCCTTAAAGCGCTTTACCTGGGCAGATGAGAACGGGGCCCAGTTCGATATGAACAACCAACACAATTG
GCAAGAAATGGTCATTAGTGTGCAGGAGATCCAATAA

Upstream 100 bases:

>100_bases
GGTTTTGGGGCCGATGGCCGGAAGGAATCGCAGGTGCGATCGCAAATCTTACACACCCAAACAAACCATCCCAATTCATC
ACTCAATAAGGAAATAGCAA

Downstream 100 bases:

>100_bases
TGAACACAGAATGCAAGACCCTCAAGCCTGTGGAAGATACCGGGTTTCAACCCATTAATCGGGCCTACAACACCGTATTC
CGTCCCAATCGATTAAGCCT

Product: enoyl-CoA hydratase/isomerase family protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSYTTFNVEIKNAIAWVTFDYPPVNIQGLPMLADLNMLAQRLETDRTIKVVVFQSAHPEIFVAHADTNFLKDMSAIAVSR
DEVKLLDLQVVLERISKLPQATIAKIEGFARGGGHEFALACDMRFAARGKAKFMQMEVAMGILPCGGGASRMARQIGLGR
ALEIILGAKDFDADQAEAYGTINKAFDPEEIGPFVEALANRIALWPAESINACKQSVYASIDKPIDEALQEEAYWLYQAT
SQTPALKRFTWADENGAQFDMNNQHNWQEMVISVQEIQ

Sequences:

>Translated_278_residues
MSYTTFNVEIKNAIAWVTFDYPPVNIQGLPMLADLNMLAQRLETDRTIKVVVFQSAHPEIFVAHADTNFLKDMSAIAVSR
DEVKLLDLQVVLERISKLPQATIAKIEGFARGGGHEFALACDMRFAARGKAKFMQMEVAMGILPCGGGASRMARQIGLGR
ALEIILGAKDFDADQAEAYGTINKAFDPEEIGPFVEALANRIALWPAESINACKQSVYASIDKPIDEALQEEAYWLYQAT
SQTPALKRFTWADENGAQFDMNNQHNWQEMVISVQEIQ
>Mature_277_residues
SYTTFNVEIKNAIAWVTFDYPPVNIQGLPMLADLNMLAQRLETDRTIKVVVFQSAHPEIFVAHADTNFLKDMSAIAVSRD
EVKLLDLQVVLERISKLPQATIAKIEGFARGGGHEFALACDMRFAARGKAKFMQMEVAMGILPCGGGASRMARQIGLGRA
LEIILGAKDFDADQAEAYGTINKAFDPEEIGPFVEALANRIALWPAESINACKQSVYASIDKPIDEALQEEAYWLYQATS
QTPALKRFTWADENGAQFDMNNQHNWQEMVISVQEIQ

Specific function: Unknown

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI68989263, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI20127408, Length=198, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=30.2631578947368, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=30.2631578947368, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI157694520, Length=177, Percent_Identity=31.638418079096, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4502327, Length=151, Percent_Identity=37.0860927152318, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI194097323, Length=228, Percent_Identity=25.4385964912281, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788682, Length=186, Percent_Identity=33.8709677419355, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790281, Length=185, Percent_Identity=32.972972972973, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787659, Length=192, Percent_Identity=29.1666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558304, Length=189, Percent_Identity=29.1005291005291, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=155, Percent_Identity=35.4838709677419, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144276, Length=199, Percent_Identity=31.6582914572864, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508953, Length=199, Percent_Identity=31.6582914572864, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=199, Percent_Identity=31.6582914572864, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=231, Percent_Identity=27.7056277056277, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=236, Percent_Identity=27.5423728813559, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=138, Percent_Identity=34.0579710144928, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=226, Percent_Identity=28.3185840707965, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653477, Length=226, Percent_Identity=28.3185840707965, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653139, Length=160, Percent_Identity=34.375, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583077, Length=208, Percent_Identity=30.2884615384615, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583079, Length=208, Percent_Identity=30.2884615384615, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19921000, Length=208, Percent_Identity=30.2884615384615, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 30893; Mature: 30761

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTTFNVEIKNAIAWVTFDYPPVNIQGLPMLADLNMLAQRLETDRTIKVVVFQSAHPEI
CCEEEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
FVAHADTNFLKDMSAIAVSRDEVKLLDLQVVLERISKLPQATIAKIEGFARGGGHEFALA
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
CDMRFAARGKAKFMQMEVAMGILPCGGGASRMARQIGLGRALEIILGAKDFDADQAEAYG
ECCHHHHCCCHHHHHEEEHHEEEECCCCHHHHHHHHCCCHHHHEEECCCCCCCCHHHHHC
TINKAFDPEEIGPFVEALANRIALWPAESINACKQSVYASIDKPIDEALQEEAYWLYQAT
CCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEC
SQTPALKRFTWADENGAQFDMNNQHNWQEMVISVQEIQ
CCCCCHHEEEECCCCCCEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SYTTFNVEIKNAIAWVTFDYPPVNIQGLPMLADLNMLAQRLETDRTIKVVVFQSAHPEI
CEEEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCEE
FVAHADTNFLKDMSAIAVSRDEVKLLDLQVVLERISKLPQATIAKIEGFARGGGHEFALA
EEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
CDMRFAARGKAKFMQMEVAMGILPCGGGASRMARQIGLGRALEIILGAKDFDADQAEAYG
ECCHHHHCCCHHHHHEEEHHEEEECCCCHHHHHHHHCCCHHHHEEECCCCCCCCHHHHHC
TINKAFDPEEIGPFVEALANRIALWPAESINACKQSVYASIDKPIDEALQEEAYWLYQAT
CCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEEEC
SQTPALKRFTWADENGAQFDMNNQHNWQEMVISVQEIQ
CCCCCHHEEEECCCCCCEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]