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The map label for this gene is nlpD [C]

Identifier: 158334675

GI number: 158334675

Start: 1495318

End: 1497003

Strand: Reverse

Name: nlpD [C]

Synonym: AM1_1508

Alternate gene names: 158334675

Gene position: 1497003-1495318 (Counterclockwise)

Preceding gene: 158334676

Following gene: 158334674

Centisome position: 23.02

GC content: 50.12

Gene sequence:

>1686_bases
ATGATCACGGTCAGTGCCATCGGCGGACTAACAACTGGGCAGACGGCTGTAGCTGCCGTTTCTCCGGCTCATCAAAAGCT
ATCCACCTCTACATCTGTGCAGTTGCCAGATCTGATCGGTTCTCCTCGATATAAATTATCGACCTATTCAAACCAGAACC
TCACCCAGTCCTCTAGGCTATTTCAACAGCGGATTGTGCAGCGCTCATCTGCACTCATTGCCTCTGAGCCGACTCTAGGG
TCTAAGCCCACTACATTGCTGACTACTAAACCGGTTGGTTCTCTGGCCCTTAAATCTGCACCTCTGGAGTCTGAAAGATC
TTCTAAATCACTAGTGTCTAAGGCAGGCGTTTCTTTCACGCAAAGTACCTTGGTTGGAGTGTCTCAAGAGTTGGCTGACG
AGCTGATGACTCCCTTGACCTCTAAAAATCTGCTAGAAGCCATCGATATTCTCGACCTTGACAATATTGAAGAGAGTTTA
GAACTCAGCACATCAGCCATCCTAGAGGTGGAGCCTATCCTGTTGGCTGAGTTACCTAGCCAACCCCTACTTGATTTAGA
TGAGCTTCTGCCTCAATCCCAACAGTCTGATGTTGAGTTGAGTTCAGCCTCTATTAACAATCCCTTAGACTTGTCTGCCA
CCCTTGAGGGCAACCCCCAAGGGATTGAATCTCTGGATGTCTCAACGTCTGAGAAAGATAGCCCTGAGGAAACGACTGCT
GTCAAATCAGTGGACTCTACCTCCCTGGCTGTCCTCCCCGATATCGATTTGTCTCAAACGATCATTCCGAACGAGCAAAA
TTCAGCCCTCATCGACTCTGGAGCGATAGTTCATCAGGTCAAACCGGGGGAGACGCTAGACGATATCTCTCGCCTTTACC
AGGTTTCGGCGAAGGAAATTACGAAGGCGAATCGCATTAGTGATCCAGCTTCTATTGGCCCCACAACGAAGCTTCGCATT
CCTGCCCATCAATCCCTTGCCTTGTCGTTAACAACAGTTGAGGACATTGTTGCTCTTAACGATTCTGAGACAAAGACGAA
GCCTAGTGATGTGTTAGGGGAAGGGGAAAAGACACCGGTTGAAACATCCAAGGAGCCTAAAGCAACCCAGGATGATACCA
AGTCTCTCTCAACTAAAACTTCTCCGCCGGTCGCCATTCTACCGATTCAGTCCGCCCCCAGTACGAAGTTAAATAGTGAT
GCGACGAAGATCGCCACTCGTAATCTGTTGCCTCAGGTTCCGAGTTTAGAGTTACCACCTCTCTCTTCCGTTGATCGTTA
CCTCCCTAGCCAAATGCTGCCGGGCCCCCAAAAGTATTTGTGGCCTGCTAAAGGCATTCTGACTTCTGGGTTCGGCTGGC
GTTGGGGACGACCCCATCGGGGTATCGATATTGCTGCCCCTGTGGGTACACCGGTTATAGCATCTGCCCCTGGCATTGTG
ACCACTGCGGGCTGGAATCGCTGGGGATATGGCAATTTAGTTGAGATCCGTCACCCAGATGGTAGCTTGACCTTATATGC
CCATAACCACCGTATTAAAACCCGCGTCGGACAATCTGTTTACCAAGGCCAACAGATTGCTGAGATGGGGAGCACTGGAC
TCAGTACTGGGCCTCACACCCACTTCGAACTCCATCCTGCGGGTAAAGGTGCGATTAACCCGGTTCCCTTCCTTAGAAAG
CTCTAA

Upstream 100 bases:

>100_bases
GTCCTCATTGAAACGAGAAATTCCGCAGAAGATTGATATCACTTCGTCAGGGGTATCAACTCTCCTTCGTCGAACTCGTT
CTGTCAGTGTTCTAGGTTTC

Downstream 100 bases:

>100_bases
AGGCATTCATAGAATACTCAAAGAACAACGAAAAGGCCATGAATATATTCATGGCCTTTTCGTTGTTCTTTGGAATTGGA
TTAAGTCAGTCTTCACTTCT

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MITVSAIGGLTTGQTAVAAVSPAHQKLSTSTSVQLPDLIGSPRYKLSTYSNQNLTQSSRLFQQRIVQRSSALIASEPTLG
SKPTTLLTTKPVGSLALKSAPLESERSSKSLVSKAGVSFTQSTLVGVSQELADELMTPLTSKNLLEAIDILDLDNIEESL
ELSTSAILEVEPILLAELPSQPLLDLDELLPQSQQSDVELSSASINNPLDLSATLEGNPQGIESLDVSTSEKDSPEETTA
VKSVDSTSLAVLPDIDLSQTIIPNEQNSALIDSGAIVHQVKPGETLDDISRLYQVSAKEITKANRISDPASIGPTTKLRI
PAHQSLALSLTTVEDIVALNDSETKTKPSDVLGEGEKTPVETSKEPKATQDDTKSLSTKTSPPVAILPIQSAPSTKLNSD
ATKIATRNLLPQVPSLELPPLSSVDRYLPSQMLPGPQKYLWPAKGILTSGFGWRWGRPHRGIDIAAPVGTPVIASAPGIV
TTAGWNRWGYGNLVEIRHPDGSLTLYAHNHRIKTRVGQSVYQGQQIAEMGSTGLSTGPHTHFELHPAGKGAINPVPFLRK
L

Sequences:

>Translated_561_residues
MITVSAIGGLTTGQTAVAAVSPAHQKLSTSTSVQLPDLIGSPRYKLSTYSNQNLTQSSRLFQQRIVQRSSALIASEPTLG
SKPTTLLTTKPVGSLALKSAPLESERSSKSLVSKAGVSFTQSTLVGVSQELADELMTPLTSKNLLEAIDILDLDNIEESL
ELSTSAILEVEPILLAELPSQPLLDLDELLPQSQQSDVELSSASINNPLDLSATLEGNPQGIESLDVSTSEKDSPEETTA
VKSVDSTSLAVLPDIDLSQTIIPNEQNSALIDSGAIVHQVKPGETLDDISRLYQVSAKEITKANRISDPASIGPTTKLRI
PAHQSLALSLTTVEDIVALNDSETKTKPSDVLGEGEKTPVETSKEPKATQDDTKSLSTKTSPPVAILPIQSAPSTKLNSD
ATKIATRNLLPQVPSLELPPLSSVDRYLPSQMLPGPQKYLWPAKGILTSGFGWRWGRPHRGIDIAAPVGTPVIASAPGIV
TTAGWNRWGYGNLVEIRHPDGSLTLYAHNHRIKTRVGQSVYQGQQIAEMGSTGLSTGPHTHFELHPAGKGAINPVPFLRK
L
>Mature_561_residues
MITVSAIGGLTTGQTAVAAVSPAHQKLSTSTSVQLPDLIGSPRYKLSTYSNQNLTQSSRLFQQRIVQRSSALIASEPTLG
SKPTTLLTTKPVGSLALKSAPLESERSSKSLVSKAGVSFTQSTLVGVSQELADELMTPLTSKNLLEAIDILDLDNIEESL
ELSTSAILEVEPILLAELPSQPLLDLDELLPQSQQSDVELSSASINNPLDLSATLEGNPQGIESLDVSTSEKDSPEETTA
VKSVDSTSLAVLPDIDLSQTIIPNEQNSALIDSGAIVHQVKPGETLDDISRLYQVSAKEITKANRISDPASIGPTTKLRI
PAHQSLALSLTTVEDIVALNDSETKTKPSDVLGEGEKTPVETSKEPKATQDDTKSLSTKTSPPVAILPIQSAPSTKLNSD
ATKIATRNLLPQVPSLELPPLSSVDRYLPSQMLPGPQKYLWPAKGILTSGFGWRWGRPHRGIDIAAPVGTPVIASAPGIV
TTAGWNRWGYGNLVEIRHPDGSLTLYAHNHRIKTRVGQSVYQGQQIAEMGSTGLSTGPHTHFELHPAGKGAINPVPFLRK
L

Specific function: May Be Involved In Stationary-Phase Survival. [C]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

Organism=Escherichia coli, GI1789099, Length=120, Percent_Identity=44.1666666666667, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082174, Length=282, Percent_Identity=28.7234042553192, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87081989, Length=99, Percent_Identity=44.4444444444444, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082297, Length=125, Percent_Identity=36.8, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR007340
- InterPro:   IPR016047
- InterPro:   IPR002886 [H]

Pfam domain/function: PF04225 OapA; PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 59710; Mature: 59710

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVSAIGGLTTGQTAVAAVSPAHQKLSTSTSVQLPDLIGSPRYKLSTYSNQNLTQSSRL
CEEEEECCCCCCCCHHEEEECCHHHHHCCCCCEECHHHHCCCCEEEEECCCCCCHHHHHH
FQQRIVQRSSALIASEPTLGSKPTTLLTTKPVGSLALKSAPLESERSSKSLVSKAGVSFT
HHHHHHHHHHCEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHCCCHH
QSTLVGVSQELADELMTPLTSKNLLEAIDILDLDNIEESLELSTSAILEVEPILLAELPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHEECCCC
QPLLDLDELLPQSQQSDVELSSASINNPLDLSATLEGNPQGIESLDVSTSEKDSPEETTA
CCCCCHHHHCCCCCCCCCEEHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
VKSVDSTSLAVLPDIDLSQTIIPNEQNSALIDSGAIVHQVKPGETLDDISRLYQVSAKEI
HHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHH
TKANRISDPASIGPTTKLRIPAHQSLALSLTTVEDIVALNDSETKTKPSDVLGEGEKTPV
HHHHCCCCCCCCCCCEEEECCCCCCEEEEEEEHHHHHEECCCCCCCCCHHHHCCCCCCCC
ETSKEPKATQDDTKSLSTKTSPPVAILPIQSAPSTKLNSDATKIATRNLLPQVPSLELPP
CCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
LSSVDRYLPSQMLPGPQKYLWPAKGILTSGFGWRWGRPHRGIDIAAPVGTPVIASAPGIV
CHHHHHHCCHHHCCCCHHHCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCEECCCCEE
TTAGWNRWGYGNLVEIRHPDGSLTLYAHNHRIKTRVGQSVYQGQQIAEMGSTGLSTGPHT
EECCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
HFELHPAGKGAINPVPFLRKL
EEEECCCCCCCCCCCHHHHCC
>Mature Secondary Structure
MITVSAIGGLTTGQTAVAAVSPAHQKLSTSTSVQLPDLIGSPRYKLSTYSNQNLTQSSRL
CEEEEECCCCCCCCHHEEEECCHHHHHCCCCCEECHHHHCCCCEEEEECCCCCCHHHHHH
FQQRIVQRSSALIASEPTLGSKPTTLLTTKPVGSLALKSAPLESERSSKSLVSKAGVSFT
HHHHHHHHHHCEEECCCCCCCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHCCCHH
QSTLVGVSQELADELMTPLTSKNLLEAIDILDLDNIEESLELSTSAILEVEPILLAELPS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHEECCCC
QPLLDLDELLPQSQQSDVELSSASINNPLDLSATLEGNPQGIESLDVSTSEKDSPEETTA
CCCCCHHHHCCCCCCCCCEEHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHH
VKSVDSTSLAVLPDIDLSQTIIPNEQNSALIDSGAIVHQVKPGETLDDISRLYQVSAKEI
HHCCCCCCEEEECCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHH
TKANRISDPASIGPTTKLRIPAHQSLALSLTTVEDIVALNDSETKTKPSDVLGEGEKTPV
HHHHCCCCCCCCCCCEEEECCCCCCEEEEEEEHHHHHEECCCCCCCCCHHHHCCCCCCCC
ETSKEPKATQDDTKSLSTKTSPPVAILPIQSAPSTKLNSDATKIATRNLLPQVPSLELPP
CCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
LSSVDRYLPSQMLPGPQKYLWPAKGILTSGFGWRWGRPHRGIDIAAPVGTPVIASAPGIV
CHHHHHHCCHHHCCCCHHHCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCEECCCCEE
TTAGWNRWGYGNLVEIRHPDGSLTLYAHNHRIKTRVGQSVYQGQQIAEMGSTGLSTGPHT
EECCCCCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
HFELHPAGKGAINPVPFLRKL
EEEECCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]