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The map label for this gene is arcB [C]

Identifier: 158334668

GI number: 158334668

Start: 1488544

End: 1490184

Strand: Direct

Name: arcB [C]

Synonym: AM1_1500

Alternate gene names: 158334668

Gene position: 1488544-1490184 (Clockwise)

Preceding gene: 158334667

Following gene: 158334669

Centisome position: 22.89

GC content: 46.74

Gene sequence:

>1641_bases
ATGAAAAATAGCACTGCGAATATTTTGATTGTTGATGACAACGTGGACAACCTAAATGTCTTAGCTGGAATGTTAGCAGA
ACAAAACTATAAGGTCAGACGAGCCATTAATGGATCAATTGCACTCAGAGCAATCAAAGCGTCGATTCCTGATCTAATTT
TGCTAGATATTGTGTTACCAGATATGACTGGATATGATATTTGCACCCAATTAAAACAGCATCCAAGCACCCAGGACATC
CCGGTGATTTTCATTAGTTCCCTCAATGACACCGAGGACAAAGTGAAGGCCTTTGCGGTAGGCGGCGTGGATTATGTGTC
TAAACCCTTCGAAATGGCTGAAGTTTGCGCTCGGATCCGCAATCAGCTAGAAATTCAGTTCGCAAAGGCAGAAATCGAAT
CCCTCAATGCCGAGTTGGAGCAGCGCGTTCAAGAACGAACCGCTGAACTAACTGCCGTTACTGTAACCCTAGAGAAACAG
ATCCAGGAACGCCAAAAAGCCGAACAGGCCTTGCGACACAGTGAAAGTCGCTTCCGGGCAATGATTGAAAATGCGTCTGA
TCTCATCCTTTTACTCGATCCACAAGGGATAGTTCATTACTCTAGCCCCTCTGTGGAAAGGAATTTGGGATATCTCCCCA
CCGATCTGCAGGGGCAGTCCTTAGTCCATTTACTCCATCCCCAGGATCAGTCTAGTATTACCCAATTATTAGCCGAGGTA
CTGGCAACGCCAAGCAAAGTTGCCGTTCCCCTAGAAATTCGGTGGCAGCATCAAGCGGGACACTGGTGCACACTAGAAGC
GATGGCCCAACAGTTTTCTGATACCACCGGATTTTCCGGCATTGTGGTCAATGCTAGAGATATTACCGAACGACAAAAAA
TGGAGGCGATGCAACGAGCCTTAGAACAGGAACAAGAGTTAAGTGAGCTGAAACTCCGCTTTTTCTCCATGGCATCCCAT
GAGTTTCGGACGCCCCTAAGTGTCATTCTGATGGCAGCTCAGATTCTTGGAAGCTCGGAGTCCCAGAGCCTAGACAACAA
ACAACAGCGGAATATTGAGCGTATCCATACGAGCGCGCAATATTTGAAAAAGATGCTAGCAGATATCTTAGATATTGCTC
GGTTAGAAGCACAAAAAAGGGAGTTCAATCCGCGACCTGTTTGCGTGAAAACGATGTGCGATCGCATCCTGGATACTCAG
CAAACCTCCCATGGGGGAATTCCCAGAATTCGCTGTGCCTATACGGGGTTATCTGCGGAAATAGCCCTAGATCCGGATCT
GTTCCAGTCTATTCTGAACAATCTGCTTGCCAATGCCCTTAAGTATTCAGCCCCAGAACAGTTGGTGCAGGTCAAATTAA
CGCAAGAGTTAGACCAAATTGAATTAATGATCATCGATCAAGGCATTGGGATTCCCAAGGCTAGTCAATCCCAATTATTT
GAAGCCTTTCATCGGGGGGATAATGTGGGTGAGATCGAAGGATCAGGTTTGGGATTGGCCATCGTCAAAAAATGTGTTGA
TCTCCATGGTGGCCATCTGTCATTTGTGAGTGAGGCTTCTGGTACCACCTTTACGGTACGATTGCCGATCCAGACCAATC
GACACCAGGCTGATCCACTCATTAGACAGACCGTAGCTTAG

Upstream 100 bases:

>100_bases
TGAAAGGATCGAAACTAGTTTGTCCCTTTAGCAGTGCAAGTATCCCTTTTATTGCCAACAATATGGGAGACCCAAACTTA
AATAGATTAAATCACGAACA

Downstream 100 bases:

>100_bases
GCAGTAATGGTAGGGGGGACATGAGACTTTTACTGGTAGAAGATGACTACCCACTGGCAGCCGTTTTTGCGGAAGCCCTG
GAAGATTCTGGCTATATCGT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKNSTANILIVDDNVDNLNVLAGMLAEQNYKVRRAINGSIALRAIKASIPDLILLDIVLPDMTGYDICTQLKQHPSTQDI
PVIFISSLNDTEDKVKAFAVGGVDYVSKPFEMAEVCARIRNQLEIQFAKAEIESLNAELEQRVQERTAELTAVTVTLEKQ
IQERQKAEQALRHSESRFRAMIENASDLILLLDPQGIVHYSSPSVERNLGYLPTDLQGQSLVHLLHPQDQSSITQLLAEV
LATPSKVAVPLEIRWQHQAGHWCTLEAMAQQFSDTTGFSGIVVNARDITERQKMEAMQRALEQEQELSELKLRFFSMASH
EFRTPLSVILMAAQILGSSESQSLDNKQQRNIERIHTSAQYLKKMLADILDIARLEAQKREFNPRPVCVKTMCDRILDTQ
QTSHGGIPRIRCAYTGLSAEIALDPDLFQSILNNLLANALKYSAPEQLVQVKLTQELDQIELMIIDQGIGIPKASQSQLF
EAFHRGDNVGEIEGSGLGLAIVKKCVDLHGGHLSFVSEASGTTFTVRLPIQTNRHQADPLIRQTVA

Sequences:

>Translated_546_residues
MKNSTANILIVDDNVDNLNVLAGMLAEQNYKVRRAINGSIALRAIKASIPDLILLDIVLPDMTGYDICTQLKQHPSTQDI
PVIFISSLNDTEDKVKAFAVGGVDYVSKPFEMAEVCARIRNQLEIQFAKAEIESLNAELEQRVQERTAELTAVTVTLEKQ
IQERQKAEQALRHSESRFRAMIENASDLILLLDPQGIVHYSSPSVERNLGYLPTDLQGQSLVHLLHPQDQSSITQLLAEV
LATPSKVAVPLEIRWQHQAGHWCTLEAMAQQFSDTTGFSGIVVNARDITERQKMEAMQRALEQEQELSELKLRFFSMASH
EFRTPLSVILMAAQILGSSESQSLDNKQQRNIERIHTSAQYLKKMLADILDIARLEAQKREFNPRPVCVKTMCDRILDTQ
QTSHGGIPRIRCAYTGLSAEIALDPDLFQSILNNLLANALKYSAPEQLVQVKLTQELDQIELMIIDQGIGIPKASQSQLF
EAFHRGDNVGEIEGSGLGLAIVKKCVDLHGGHLSFVSEASGTTFTVRLPIQTNRHQADPLIRQTVA
>Mature_546_residues
MKNSTANILIVDDNVDNLNVLAGMLAEQNYKVRRAINGSIALRAIKASIPDLILLDIVLPDMTGYDICTQLKQHPSTQDI
PVIFISSLNDTEDKVKAFAVGGVDYVSKPFEMAEVCARIRNQLEIQFAKAEIESLNAELEQRVQERTAELTAVTVTLEKQ
IQERQKAEQALRHSESRFRAMIENASDLILLLDPQGIVHYSSPSVERNLGYLPTDLQGQSLVHLLHPQDQSSITQLLAEV
LATPSKVAVPLEIRWQHQAGHWCTLEAMAQQFSDTTGFSGIVVNARDITERQKMEAMQRALEQEQELSELKLRFFSMASH
EFRTPLSVILMAAQILGSSESQSLDNKQQRNIERIHTSAQYLKKMLADILDIARLEAQKREFNPRPVCVKTMCDRILDTQ
QTSHGGIPRIRCAYTGLSAEIALDPDLFQSILNNLLANALKYSAPEQLVQVKLTQELDQIELMIIDQGIGIPKASQSQLF
EAFHRGDNVGEIEGSGLGLAIVKKCVDLHGGHLSFVSEASGTTFTVRLPIQTNRHQADPLIRQTVA

Specific function: Member Of The Two-Component Regulatory System Arcb/Arca. Sensor-Regulator Protein For Anaerobic Repression Of The Arc Modulon. Activates Arca Via A Four-Step Phosphorelay. Arcb Can Also Dephosphorylate Arca By A Reverse Phosphorelay Involving His- 717 And

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=412, Percent_Identity=28.1553398058252, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=30.3501945525292, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788713, Length=297, Percent_Identity=28.956228956229, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=31.8367346938775, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=27.734375, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=383, Percent_Identity=28.1984334203655, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082128, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=243, Percent_Identity=26.7489711934156, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790860, Length=118, Percent_Identity=33.0508474576271, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=246, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789808, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=137, Percent_Identity=32.8467153284672, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=32.7433628318584, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787894, Length=297, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=382, Percent_Identity=24.0837696335079, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786784, Length=174, Percent_Identity=32.183908045977, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788279, Length=243, Percent_Identity=27.9835390946502, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=27.8761061946903, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=389, Percent_Identity=23.9074550128535, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=31.6666666666667, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788394, Length=138, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=24.9027237354086, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786911, Length=184, Percent_Identity=29.8913043478261, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082012, Length=133, Percent_Identity=32.3308270676692, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=139, Percent_Identity=28.0575539568345, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=364, Percent_Identity=25.8241758241758, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60841; Mature: 60841

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSTANILIVDDNVDNLNVLAGMLAEQNYKVRRAINGSIALRAIKASIPDLILLDIVLP
CCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCEEHHHHCC
DMTGYDICTQLKQHPSTQDIPVIFISSLNDTEDKVKAFAVGGVDYVSKPFEMAEVCARIR
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHEECCHHHHCCCHHHHHHHHHHH
NQLEIQFAKAEIESLNAELEQRVQERTAELTAVTVTLEKQIQERQKAEQALRHSESRFRA
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
MIENASDLILLLDPQGIVHYSSPSVERNLGYLPTDLQGQSLVHLLHPQDQSSITQLLAEV
HHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
LATPSKVAVPLEIRWQHQAGHWCTLEAMAQQFSDTTGFSGIVVNARDITERQKMEAMQRA
HCCCCCEEEEEEEEEECCCCCEEEHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
LEQEQELSELKLRFFSMASHEFRTPLSVILMAAQILGSSESQSLDNKQQRNIERIHTSAQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHH
YLKKMLADILDIARLEAQKREFNPRPVCVKTMCDRILDTQQTSHGGIPRIRCAYTGLSAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEE
IALDPDLFQSILNNLLANALKYSAPEQLVQVKLTQELDQIELMIIDQGIGIPKASQSQLF
EEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
EAFHRGDNVGEIEGSGLGLAIVKKCVDLHGGHLSFVSEASGTTFTVRLPIQTNRHQADPL
HHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCHH
IRQTVA
HHHHCC
>Mature Secondary Structure
MKNSTANILIVDDNVDNLNVLAGMLAEQNYKVRRAINGSIALRAIKASIPDLILLDIVLP
CCCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHCCCCCEEHHHHCC
DMTGYDICTQLKQHPSTQDIPVIFISSLNDTEDKVKAFAVGGVDYVSKPFEMAEVCARIR
CCCCHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHEECCHHHHCCCHHHHHHHHHHH
NQLEIQFAKAEIESLNAELEQRVQERTAELTAVTVTLEKQIQERQKAEQALRHSESRFRA
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
MIENASDLILLLDPQGIVHYSSPSVERNLGYLPTDLQGQSLVHLLHPQDQSSITQLLAEV
HHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
LATPSKVAVPLEIRWQHQAGHWCTLEAMAQQFSDTTGFSGIVVNARDITERQKMEAMQRA
HCCCCCEEEEEEEEEECCCCCEEEHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHH
LEQEQELSELKLRFFSMASHEFRTPLSVILMAAQILGSSESQSLDNKQQRNIERIHTSAQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHH
YLKKMLADILDIARLEAQKREFNPRPVCVKTMCDRILDTQQTSHGGIPRIRCAYTGLSAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEE
IALDPDLFQSILNNLLANALKYSAPEQLVQVKLTQELDQIELMIIDQGIGIPKASQSQLF
EEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHH
EAFHRGDNVGEIEGSGLGLAIVKKCVDLHGGHLSFVSEASGTTFTVRLPIQTNRHQADPL
HHHHCCCCCCEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCCCCHH
IRQTVA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]